cis-terpenones as an effective chemopreventive agent against aflatoxin B1-induced cytotoxicity and TCDD-induced P450 1A/B activity in HepG2 cells

Chemical Research in Toxicology

Volumn 19, Issue 11, 2006, Pages 1415-1419

  Zhou, Qibing ^a   Xie, Hang ^b   Zhang, Lin ^a   Stewart, Jennifer K ^a   Gu, Xing Xing ^b   Ryan, John J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AFLATOXIN B1; CARCINOGEN; CHLOROPHYLL; CYTOCHROME P450 1A; HEXAHYDRO 2 ACETYLOXYTRIMETHYLPHENANTHREN 9(10H) ONE; HEXAHYDRO 2 HYDROXYTRIMETHYLPHENANTHREN 9(10H) ONE; HEXAHYDRO 2 METHOXYTRIMETHYLPHENANTHREN 9(10H) ONE; KETONE DERIVATIVE; NATURAL PRODUCT; OLTIPRAZ; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER RISK; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FOOD CONTAMINATION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; LIVER TOXICITY; STRUCTURE ACTIVITY RELATION;

AFLATOXIN B1; CARCINOGENS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMOPREVENTION; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; TERPENES; TETRACHLORODIBENZODIOXIN;

EID: 33845260553     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx0601307     Document Type: Article

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