Calcium and ER stress mediate hepatic apoptosis after burn injury

Journal of Cellular and Molecular Medicine

Volumn 13, Issue 8 B, 2009, Pages 1857-1865

  Jeschke, Marc G ^a,b   Gauglitz, Gerd G ^a,b   Song, Juquan ^a,b   Kulp, Gabriela A ^a,b   Finnerty, Celeste C ^a,b   Cox, Robert A ^a,b   Barral, José M ^a,b   Herndon, David N ^a,b   Boehning, Darren ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; Calcium; ER stress; Liver; Thermal injury; Unfolded protein response

Indexed keywords

RATTUS;

EID: 70149091640     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00644.x     Document Type: Article

References (40)

1. Brigham PA, McLoughlin E. Burn incidence and medical care use in the United States: estimates, trends and data sources. J Burn Care Rehabil. 1996 17 : 95 107.
2. World Health Organization (WHO). A graphical overview of the global burden of injuries. The injury chart book. Volume 29. Geneva : WHO 2002.
3. Herndon DN, Tompkins RG. Support of the metabolic response to burn injury. Lancet. 2004 363 : 1895 1902.
4. Herndon DN, Hart DW, Wolf SE, et al. Reversal of catabolism by beta-blockade after severe burns. N Engl J Med. 2001 345 : 1223 1229.
5. van den Berge G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. New Engl J Med. 2001 345 : 1359 1367.
6. Finnerty CC, Herndon DN, Przkora R, et al. Cytokine expression profile over time in severely burned pediatric patients. Shock. 2006 26 : 13 9.
7. Tracey KJ, Fong Y, Hesse DG, et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature. 1987 330 : 662 664.
8. Tracey KJ, Lowry SF, Fahey TJ, 3rd., et al. Cachectin/tumor necrosis factor induces lethal shock and stress hormone responses in the dog. Surg Gynecol Obstet. 1987 164 : 415 422.
9. Moshage H. Cytokines and the hepatic acute phase response. J Pathol. 1997 181 : 257 266.
10. Jeschke MG, Low JF, Spies M, et al. Cell proliferation, apoptosis, NF-kappaB expression, enzyme, protein, and weight changes in livers of burned rats. Am J Physiol Gastrointest Liver Physiol. 2001 280 : G1314 20.
11. Jeschke MG, Micak RP, Finnerty CC, et al. Changes in liver function and size after a severe thermal injury. Shock. 2007 28 : 172 177.
12. Jeschke MG, Rensing H, Klein D, et al. Insulin prevents liver damage and preserves liver function in lipopolysaccharide-induced endotoxemic rats. J Hepatol. 2005 42 : 870 879.
13. Klein D, Schubert T, Horch RE, et al. Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma. Ann Surg. 2004 240 : 340 349.
14. Price LA, Thombs B, Chen CL, et al. Liver disease in burn injury: evidence from a national sample of 31,338 adult patients. J Burns Wounds. 2007 7 : e1.
15. Jeschke MG, Barrow RE, Herndon DN. Extended hypermetabolic response of the liver in severely burned pediatric patients. Arch Surg. 2004 139 : 641 647.
16. Lockshin RA, Zakeri Z. Cell death in health and disease. J Cell Mol Med. 2007 11 : 1214 1224.
17. Reed JC. Apoptosis-based therapies. Nat Rev Drug Discov. 2002 1 : 111 121.
18. Yin XM, Ding WX. Death receptor activation-induced hepatocyte apoptosis and liver injury. Curr Mol Med. 2003 3 : 491 508.
19. Herndon DN, Wilmore DW, Mason AD Jr. Development and analysis of a small animal model simulating the human postburn hypermetabolic response. J Surg Res. 1978 25 : 394 403.
20. Boehning D, Joseph SK. Functional properties of recombinant type I and type III inositol 1, 4,5-trisphosphate receptor isoforms expressed in COS-7 cells. J Biol Chem. 2000 275 : 21492 21499.
21. Boehning D, Patterson RL, Sedaghat L, et al. Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis. Nat Cell Biol. 2003 5 : 1051 1061.
22. Wozniak AL, Wang X, Stieren ES, et al. Requirement of biphasic calcium release from the endoplasmic reticulum for Fas-mediated apoptosis. J Cell Biol. 2006 175 : 709 714.
23. Thastrup O, Cullen PJ, Drobak BK, et al. Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proc Natl Acad Sci USA. 1990 87 : 2466 2470.
24. Kawanishi T, Blank LM, Harootunian AT, et al. Ca2+ oscillations induced by hormonal stimulation of individual fura-2-loaded hepatocytes. J Biol Chem. 1989 264 : 12859 12866.
25. Burdakov D, Petersen OH, Verkhratsky A. Intraluminal calcium as a primary regulator of endoplasmic reticulum function. Cell Calcium. 2005 38 : 303 310.
26. Gorlach A, Klappa P, Kietzmann T. The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid Redox Signal. 2006 8 : 1391 1418.
27. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol. 2007 8 : 519 529.
28. Khan AA, Soloski MJ, Sharp AH, et al. Lymphocyte apoptosis: mediation by increased type 3 inositol 1,4,5-trisphosphate receptor. Science. 1996 273 : 503 507.
29. Puthalakath H, O'Reilly LA, Gunn P, et al. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell. 2007 129 : 1337 1349.
30. Dong Z, Saikumar P, Weinberg JM, et al. Calcium in cell injury and death. Annu Rev Pathol. 2006 1 : 405 434.
31. Blackshaw S, Sawa A, Sharp AH, et al. Type 3 inositol 1,4,5-trisphosphate receptor modulates cell death. FASEB J. 2000 14 : 1375 1379.
32. Li C, Fox CJ, Master SR, et al. Bcl-X(L) affects Ca(2+) homeostasis by altering expression of inositol 1,4,5-trisphosphate receptors. Proc Natl Acad Sci USA. 2002 99 : 9830 9835.
33. Jayaraman T, Marks AR. T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis. Mol Cell Biol. 1997 17 : 3005 3012.
34. Hajnoczky G, Csordas G, Madesh M, et al. Control of apoptosis by IP(3) and ryanodine receptor driven calcium signals. Cell Calcium. 2000 28 : 349 363. (Pubitemid 32050825)
35. Szalai G, Krishnamurthy R, Hajnoczky G. Apoptosis driven by IP(3)-linked mitochondrial calcium signals. EMBO J. 1999 18 : 6349 6361.
36. Joseph SK, Hajnoczky G. IP3 receptors in cell survival and apoptosis: Ca2+ release and beyond. Apoptosis. 2007 12 : 951 968.
37. Higuchi H, Gores GJ. Mechanisms of liver injury: an overview. Curr Mol Med. 2003 3 : 483 490.
38. Dosreis GA, Borges VM, Zin WA. The central role of Fas-ligand cell signaling in inflammatory lung diseases. J Cell Mol Med. 2004 8 : 285 293.
39. Ozcan U, Yilmaz E, Ozcan L, et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science. 2006 313 : 1137 1140.
40. Wiseman RL, Balch WE. A new pharmacology-drugging stressed folding pathways. Trends Mol Med. 2005 11 : 347 350.