Evaluation of the hepatotoxic and hepatoprotective effect of Rwandese herbal drugs on in vivo (guinea pigs barbiturate-induced sleeping time) and in vitro (rat precision-cut liver slices, PCLS) models

Experimental and Toxicologic Pathology

Volumn 62, Issue 3, 2010, Pages 289-299

  Mukazayire, Marie Jeanne ^a,b   Allaeys, Véronique ^c   Buc Calderon, Pedro ^c   Stévigny, Caroline ^a   Bigendako, Marie Josée ^b   Duez, Pierre ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b Institut de Recherche Scientifique et Technologique (IRST)   (Rwanda)

^c UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

Crassocephalum vitellinum; Guinea pigs; Guizotia scabra; Hepatoprotection; Hepatotoxicity; Microglossa pyrifolia; Ocimum lamiifolium; Rat precision cut liver slices (PCLS); Sleeping time; Vernonia lasiopus

Indexed keywords

ACETYLCYSTEINE; ALKALOID; ANTHRAQUINONE DERIVATIVE; CARBON TETRACHLORIDE; CRASSOCEPHALUM VITELLINUM EXTRACT; FLAVONOID; GUIZOTIA SCABRA EXTRACT; LIVER PROTECTIVE AGENT; MICROGLOSSA PYRIFOLIA EXTRACT; OCIMUM LAMIIFOLIUM EXTRACT; PARACETAMOL; PHYTOSTEROL; PLANT EXTRACT; SAPONIN; TANNIN; TERPENOID; UNCLASSIFIED DRUG; VERNONIA LASIOPUS EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASIL; CONTROLLED STUDY; CRASSOCEPHALUM VITELLINUM; DRUG DETERMINATION; DRUG MECHANISM; DRUG SCREENING; EXPERIMENTAL GUINEA PIG; FEMALE; GUIZOTIA SCABRA; INTERMETHOD COMPARISON; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; MEDICINAL PLANT; MICROGLOSSA PYRIFOLIA; NONHUMAN; OCIMUM LAMIIFOLIUM; PHYTOCHEMISTRY; RAT; SLEEP TIME; TOXICITY TESTING; VERNONIA; VERNONIA LASIOPUS;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; BARBITURATES; DISEASE MODELS, ANIMAL; FEMALE; GUINEA PIGS; HYPNOTICS AND SEDATIVES; LIVER; MALE; OCIMUM; ORGAN CULTURE TECHNIQUES; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; RATS; RWANDA; SLEEP;

ANIMALIA; CAVIA; CRASSOCEPHALUM; GUIZOTIA SCABRA; MICROGLOSSA PYRIFOLIA; OCIMUM; RATTUS; VERNONIA LASIOPUS;

EID: 77952892146     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.04.005     Document Type: Article

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