A New Experimental Model of Isolated Perfused Pig Liver to Support Acute Hepatic Failure

Transplantation Proceedings

Volumn 39, Issue 6, 2007, Pages 2028-2030

  Carraro, A ^a   Gringeri, E ^a   Calabrese, F ^a   Violi, P ^a   Brolese, A ^a   Zanus, G ^a   Boccagni, P ^a   Valente, M L ^a   Bassi, D ^a   D'Amico Jr , F ^a   D'Amico, D F ^a   Cillo, U ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL TISSUE; ARTERIAL BLOOD; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; FEMALE; GRAFT RECIPIENT; HEMODYNAMICS; HOMEOSTASIS; ISOLATED LIVER; LIVER FAILURE; LIVER PERFUSION; METABOLIC CAPACITY; NONHUMAN; PORTAL VEIN BLOOD; PRIORITY JOURNAL; SWINE;

ANIMALS; DISEASE MODELS, ANIMAL; EXTRACORPOREAL CIRCULATION; HUMANS; LIVER; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; PERFUSION; SWINE; WAITING LISTS;

EID: 34547566447     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2007.05.070     Document Type: Article

References (12)

1. Lee W.M. Acute liver failure. Am J Med 96 suppl 1A (1994) 3S
2. Williams R., and Gimson A.E. Intensive liver care and management of acute liver failure. Dig Dis Sci 36 (1991) 820
3. Munoz S.J. Difficult management problems in fulminant hepatic failure. Semin Liver Dis 13 (1993) 395
4. Nishimura A., Umehara Y., Umehara M., et al. Plasma exchange-based plasma recycling dialysis system as a potential platform for artificial liver support. Artif Organs 30 (2006) 629
5. Fernandez-Merino F.J., Nuno-Garza J., Lopez-Hervas P., et al. Survival and complication rates in liver transplant patients showing primary dysfunction versus normofunction. Transplant Proc 35 (2003) 1793
6. Chamuleau R.A., Poyck P.P., and van de Kerkhove M.P. Bioartificial livers: its pros and cons. Ther Apher Dial 10 (2006) 168
7. Riedel G.L., Scholle J.L., Shepherd A.P., et al. Effects of hematocrit on oxygenation of the isolated perfused rat liver. Am J Physiol 245 (1983) G769
8. Kusmic C., Boggi U., Bellini R., et al. Oxidative stress in fulminant hepatic failure: comparison of two pig models with and without liver necrosis. Hepatogastroenterology 48 (2001) 762
9. Travis D.L., Paulsen A.W., and Genyk Y. Development of an in situ isolated porcine liver perfusion model for tightly controlled physiologic and pharmacologic studies. J Invest Surg 9 (1996) 131
10. Patience C., Takeuchi Y., and Weiss A.R. Infection of human cells by an endogenous retrovirus of pigs. Nature Med 3 (1997) 282
11. Deng Y.M., Tuch B.E., and Rawlinson W.D. Transmission of porcine endogenous retroviruses in severe combined immunodeficient mice xenotransplanted with fetal porcine pancreatic cells. Transplantation 70 (2000) 1010
12. Switzer W.M., Michler R.E., Shanmugam V., et al. Lack of cross species transmission of porcine endogenous retrovirus infection to non- human primate recipients of porcine cells, tissues or organs. Transplantation 71 (2001) 959