-
1
-
-
0031772126
-
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release
-
Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, and Lemasters JJ. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol Cell Biol 18: 6353-6364, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6353-6364
-
-
Bradham, C.A.1
Qian, T.2
Streetz, K.3
Trautwein, C.4
Brenner, D.A.5
Lemasters, J.J.6
-
2
-
-
0031005579
-
Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases
-
Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadeve S, Jenkins G, Hannun Y, Lemasters JJ, Thurman RG, and Brenner DA. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology 25: 1128-1135, 1997.
-
(1997)
Hepatology
, vol.25
, pp. 1128-1135
-
-
Bradham, C.A.1
Stachlewitz, R.F.2
Gao, W.3
Qian, T.4
Jayadeve, S.5
Jenkins, G.6
Hannun, Y.7
Lemasters, J.J.8
Thurman, R.G.9
Brenner, D.A.10
-
3
-
-
0032530727
-
Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver
-
Chen J, Ishac EJ, Dent P, Kinos G, and Gao B. Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver. Biochem J 334: 669-676, 1998.
-
(1998)
Biochem J
, vol.334
, pp. 669-676
-
-
Chen, J.1
Ishac, E.J.2
Dent, P.3
Kinos, G.4
Gao, B.5
-
4
-
-
0346890213
-
Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway
-
Chen W, White MA, and Cobb MH. Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway. J Biol Chem 277: 49105-49110, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 49105-49110
-
-
Chen, W.1
White, M.A.2
Cobb, M.H.3
-
5
-
-
0037186169
-
Retinoic acid inhibits hepatic Jun N-terminal kinase-dependent signaling pathway in ethanol-fed rats
-
Chung J, Chaves PRG, Russell RM, and Wang XD. Retinoic acid inhibits hepatic Jun N-terminal kinase-dependent signaling pathway in ethanol-fed rats. Oncogene 21: 1539-1547, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 1539-1547
-
-
Chung, J.1
Chaves, P.R.G.2
Russell, R.M.3
Wang, X.D.4
-
6
-
-
4243860191
-
Hepatoctye resistance to oxidative injury results from ERK-dependent inhibition of JNK activation
-
Czaja MJ and Liu H. Hepatoctye resistance to oxidative injury results from ERK-dependent inhibition of JNK activation (Abstract). Hepatology 36: 300A, 2002.
-
(2002)
Hepatology
, vol.36
-
-
Czaja, M.J.1
Liu, H.2
-
7
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252, 2000.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
8
-
-
0035889252
-
Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signaling
-
De Samaele E, Zazzeroni F, Papa S, Nguyen DU, Jin R, Jones J, Cong R, and Franzoso G. Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signaling. Nature 414: 308-313, 2001.
-
(2001)
Nature
, vol.414
, pp. 308-313
-
-
De Samaele, E.1
Zazzeroni, F.2
Papa, S.3
Nguyen, D.U.4
Jin, R.5
Jones, J.6
Cong, R.7
Franzoso, G.8
-
9
-
-
0037174934
-
JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery
-
Donovan N, Becker EB, Konish Y, and Bonni A. JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem 277: 40944-40949, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 40944-40949
-
-
Donovan, N.1
Becker, E.B.2
Konish, Y.3
Bonni, A.4
-
10
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, Lydon NB, Kantarjian H, Capdeville R, OhnoJones S, and Sawyers CL. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 344: 1031-1037, 2001.
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
Peng, B.4
Buchdunger, E.5
Ford, J.M.6
Lydon, N.B.7
Kantarjian, H.8
Capdeville, R.9
OhnoJones, S.10
Sawyers, C.L.11
-
11
-
-
0036241214
-
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner
-
Graf D, Kurz AK, Fischer R, Reinehr R, and Häussinger D. Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase-dependent manner. Gastroenterology 122: 1411-1427, 2002.
-
(2002)
Gastroenterology
, vol.122
, pp. 1411-1427
-
-
Graf, D.1
Kurz, A.K.2
Fischer, R.3
Reinehr, R.4
Häussinger, D.5
-
12
-
-
0034931503
-
c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
-
Han Z, Boyle DL, Chang L, Bennett B, Karin M, Yang L, Manning AM, and Firestein GS. c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 108: 73-81, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 73-81
-
-
Han, Z.1
Boyle, D.L.2
Chang, L.3
Bennett, B.4
Karin, M.5
Yang, L.6
Manning, A.M.7
Firestein, G.S.8
-
13
-
-
0037404039
-
Bile acid regulation of hepatic physiology. IV. Bile acids and death receptors
-
Higuchi H and Gores GJ. Bile Acid Regulation of Hepatic Physiology. IV. Bile acids and death receptors. Am J Physiol Gastrointest Liver Physiol 284: G734-G738, 2003.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Higuchi, H.1
Gores, G.J.2
-
14
-
-
85047700485
-
Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis
-
Hochedlinger K, Wagner ER, and Sabapthy K. Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis. Oncogene 21: 2441-2445, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 2441-2445
-
-
Hochedlinger, K.1
Wagner, E.R.2
Sabapthy, K.3
-
15
-
-
0032044237
-
Protein phosphatases and the regulation of MAP kinase activity
-
Keyse SM. Protein phosphatases and the regulation of MAP kinase activity. Semin Cell Dev Biol 9: 143-152, 1998.
-
(1998)
Semin Cell Dev Biol
, vol.9
, pp. 143-152
-
-
Keyse, S.M.1
-
16
-
-
0037066779
-
Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation
-
Koteish A, Yang S, Lin H, Huang X, and Diehl AM. Chronic ethanol exposure potentiates lipopolysaccharide liver injury despite inhibiting Jun N-terminal kinase and caspase 3 activation. J Biol Chem 277: 13037-13044, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 13037-13044
-
-
Koteish, A.1
Yang, S.2
Lin, H.3
Huang, X.4
Diehl, A.M.5
-
17
-
-
0033659477
-
Gene delivery of Cu/Znsuperoxide dismutase improves graft function after transplantation of fatty livers in the rat
-
Lehmann TG, Wheeler MD, Schwabe RF, Conner HD, Schoonhoven R, Bunzendahl H, Brenner DA, Jude Samulski R, Zhong Z, and Thurman RG. Gene delivery of Cu/Znsuperoxide dismutase improves graft function after transplantation of fatty livers in the rat. Hepatology 32: 1255-1264, 2000.
-
(2000)
Hepatology
, vol.32
, pp. 1255-1264
-
-
Lehmann, T.G.1
Wheeler, M.D.2
Schwabe, R.F.3
Conner, H.D.4
Schoonhoven, R.5
Bunzendahl, H.6
Brenner, D.A.7
Jude Samulski, R.8
Zhong, Z.9
Thurman, R.G.10
-
18
-
-
0036329891
-
Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells
-
Liedtke C, Plümpe J, Kubicka S, Bradham CA, Manns MP, Brenner DA, and Trautwein C. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology 36: 315-325, 2002.
-
(2002)
Hepatology
, vol.36
, pp. 315-325
-
-
Liedtke, C.1
Plümpe, J.2
Kubicka, S.3
Bradham, C.A.4
Manns, M.P.5
Brenner, D.A.6
Trautwein, C.7
-
19
-
-
0036086898
-
Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to cJun-mediated cell death from TNF-α
-
Liu H, Jones BE, Bradham C, and Czaja MJ. Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to cJun-mediated cell death from TNF-α. Am J Physiol Gastrointest Liver Physiol 282: G257-G266, 2002.
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.282
-
-
Liu, H.1
Jones, B.E.2
Bradham, C.3
Czaja, M.J.4
-
20
-
-
0036009411
-
NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun
-
Liu H, Lo CR, and Czaja MJ. NF-κB inhibition sensitizes hepatocytes to TNF-induced apoptosis through a sustained activation of JNK and c-Jun. Hepatology 35: 772-778, 2002.
-
(2002)
Hepatology
, vol.35
, pp. 772-778
-
-
Liu, H.1
Lo, C.R.2
Czaja, M.J.3
-
21
-
-
0036211298
-
Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes
-
Qiao L, Yacoub A, Studer E, Gupta S, Pei XY, Grant S, Hylemon PB, and Dent P. Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes. Hepatology 35: 779-789, 2002.
-
(2002)
Hepatology
, vol.35
, pp. 779-789
-
-
Qiao, L.1
Yacoub, A.2
Studer, E.3
Gupta, S.4
Pei, X.Y.5
Grant, S.6
Hylemon, P.B.7
Dent, P.8
-
22
-
-
0027933862
-
Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: Reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors
-
Rana B, Mischoulon D, Xie Y, Bucher NL, and Farmer SR. Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors. Mol Cell Biol 14: 5858-5869, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5858-5869
-
-
Rana, B.1
Mischoulon, D.2
Xie, Y.3
Bucher, N.L.4
Farmer, S.R.5
-
23
-
-
0036151709
-
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
-
Rao YP, Studer EJ, Stravitz T, Gupta S, Qiao L, Dent P, and Hylemon PB. Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology 35: 307-314, 2002.
-
(2002)
Hepatology
, vol.35
, pp. 307-314
-
-
Rao, Y.P.1
Studer, E.J.2
Stravitz, T.3
Gupta, S.4
Qiao, L.5
Dent, P.6
Hylemon, P.B.7
-
24
-
-
0034733547
-
The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade
-
Rust C, Karnitz LM, Paya CV, Moscat J, Simari RD, and Gores GJ. The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade. J Biol Chem 275: 20210-20216, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 20210-20216
-
-
Rust, C.1
Karnitz, L.M.2
Paya, C.V.3
Moscat, J.4
Simari, R.D.5
Gores, G.J.6
-
25
-
-
0012759969
-
JNK mediates TNF-α-induced apoptosis in hepatocytes in a transcriptionally indpendent manner
-
Schwabe RF, Bennett BL, Purbeck CA, and Brenner DA. JNK mediates TNF-α-induced apoptosis in hepatocytes in a transcriptionally indpendent manner (Abstract). Hepatology 36: 299A, 2002.
-
(2002)
Hepatology
, vol.36
-
-
Schwabe, R.F.1
Bennett, B.L.2
Purbeck, C.A.3
Brenner, D.A.4
-
26
-
-
0035400115
-
Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure
-
Streetz K, Fregien B, Plümpe J, Korber K, Kubicka S, Sass G, Bischoff SC, Manns MP, Tiegs G, and Trautwein C. Dissection of the intracellular pathways in hepatocytes suggests a role for Jun kinase and IFN regulatory factor-1 in Con A-induced liver failure. J Immunol 167: 514-523, 2001.
-
(2001)
J Immunol
, vol.167
, pp. 514-523
-
-
Streetz, K.1
Fregien, B.2
Plümpe, J.3
Korber, K.4
Kubicka, S.5
Sass, G.6
Bischoff, S.C.7
Manns, M.P.8
Tiegs, G.9
Trautwein, C.10
-
27
-
-
0035891320
-
Inhibition of JNK activation through NF-κB target genes
-
Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, and Lin A. Inhibition of JNK activation through NF-κB target genes. Nature 414: 313-317, 2001.
-
(2001)
Nature
, vol.414
, pp. 313-317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
Purcell, N.H.4
Li, Z.5
Karin, M.6
Lin, A.7
-
28
-
-
0012665183
-
JNK inhibitors protect from hepatic ischemia/reperfusion injury
-
Uehara T, Bennett B, Sakata ST, Satoh Y, and Brenner DA. JNK inhibitors protect from hepatic ischemia/reperfusion injury (Abstract). Hepatology 34: 348A, 2001.
-
(2001)
Hepatology
, vol.34
-
-
Uehara, T.1
Bennett, B.2
Sakata, S.T.3
Satoh, Y.4
Brenner, D.A.5
-
30
-
-
0035049449
-
Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release
-
Whitfield J, Neame SJ, Paquet L, Bernard O, and Ham J. Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release. Neuron 29: 629-643, 2001.
-
(2001)
Neuron
, vol.29
, pp. 629-643
-
-
Whitfield, J.1
Neame, S.J.2
Paquet, L.3
Bernard, O.4
Ham, J.5
-
31
-
-
0032185680
-
NF-κB activation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis
-
Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, and Czaja MJ. NF-κB activation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis. Am J Physiol Cell Physiol 275: C1058-C1066, 1998.
-
(1998)
Am J Physiol Cell Physiol
, vol.275
-
-
Xu, Y.1
Bialik, S.2
Jones, B.E.3
Iimuro, Y.4
Kitsis, R.N.5
Srinivasan, A.6
Brenner, D.A.7
Czaja, M.J.8
-
33
-
-
0031749682
-
Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation
-
Zwacka RM, Zhou W, Zhang Y, Darby CJ, Dudus L, Halldorson J, Oberley L, and Engelhardt JF. Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation. Nat Med 4: 698-704, 1998.
-
(1998)
Nat Med
, vol.4
, pp. 698-704
-
-
Zwacka, R.M.1
Zhou, W.2
Zhang, Y.3
Darby, C.J.4
Dudus, L.5
Halldorson, J.6
Oberley, L.7
Engelhardt, J.F.8
|