-
1
-
-
61949463911
-
IL-17 and Th17 cells
-
Korn T., Bettelli E., Oukka M., Kuchroo V.K. IL-17 and Th17 cells. Annual Review of Immunology 2009, 27:485-517.
-
(2009)
Annual Review of Immunology
, vol.27
, pp. 485-517
-
-
Korn, T.1
Bettelli, E.2
Oukka, M.3
Kuchroo, V.K.4
-
2
-
-
84873620273
-
Helper T-cell identity and evolution of differential transcriptomes and epigenomes
-
Vahedi G., Poholek C.A., Hand T.W., Laurence A., Kanno Y., O'Shea J.J., et al. Helper T-cell identity and evolution of differential transcriptomes and epigenomes. Immunological Reviews 2013, 252:24-40.
-
(2013)
Immunological Reviews
, vol.252
, pp. 24-40
-
-
Vahedi, G.1
Poholek, C.A.2
Hand, T.W.3
Laurence, A.4
Kanno, Y.5
O'Shea, J.J.6
-
3
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
Sakaguchi S., Yamaguchi T., Nomura T., Ono M. Regulatory T cells and immune tolerance. Cell 2008, 133:775-787.
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
4
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature Immunology 2005, 6:1133-1141.
-
(2005)
Nature Immunology
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
-
5
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington L.E., Hatton R.D., Mangan P.R., Turner H., Murphy T.L., Murphy K.M., et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunology 2005, 6:1123-1132.
-
(2005)
Nature Immunology
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
-
6
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
-
8
-
-
42649115767
-
TH17 cells in development: an updated view of their molecular identity and genetic programming
-
Dong C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nature Reviews Immunology 2008, 8:337-348.
-
(2008)
Nature Reviews Immunology
, vol.8
, pp. 337-348
-
-
Dong, C.1
-
9
-
-
67651001561
-
The AP-1 transcription factor Batf controls T(H)17 differentiation
-
Schraml B.U., Hildner K., Ise W., Lee W.L., Smith W.A., Solomon B., et al. The AP-1 transcription factor Batf controls T(H)17 differentiation. Nature 2009, 460:405-409.
-
(2009)
Nature
, vol.460
, pp. 405-409
-
-
Schraml, B.U.1
Hildner, K.2
Ise, W.3
Lee, W.L.4
Smith, W.A.5
Solomon, B.6
-
10
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 2008, 28:29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
-
11
-
-
58549094107
-
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
-
Huber M., Brustle A., Reinhard K., Guralnik A., Walter G., Mahiny A., et al. IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:20846-20851.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 20846-20851
-
-
Huber, M.1
Brustle, A.2
Reinhard, K.3
Guralnik, A.4
Walter, G.5
Mahiny, A.6
-
12
-
-
64049089798
-
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling
-
Chung Y., Chang S.H., Martinez G.J., Yang X.O., Nurieva R., Kang H.S., et al. Critical regulation of early Th17 cell differentiation by interleukin-1 signaling. Immunity 2009, 30:576-587.
-
(2009)
Immunity
, vol.30
, pp. 576-587
-
-
Chung, Y.1
Chang, S.H.2
Martinez, G.J.3
Yang, X.O.4
Nurieva, R.5
Kang, H.S.6
-
13
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani M., Madar A., Galan C., Sellars M., Mace K., Pauli F., et al. A validated regulatory network for Th17 cell specification. Cell 2012, 151:289-303.
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M.1
Madar, A.2
Galan, C.3
Sellars, M.4
Mace, K.5
Pauli, F.6
-
14
-
-
45749101727
-
Induction and effector functions of T(H)17 cells
-
Bettelli E., Korn T., Oukka M., Kuchroo V.K. Induction and effector functions of T(H)17 cells. Nature 2008, 453:1051-1057.
-
(2008)
Nature
, vol.453
, pp. 1051-1057
-
-
Bettelli, E.1
Korn, T.2
Oukka, M.3
Kuchroo, V.K.4
-
15
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson N.J., Boniface K., Chan J.R., McKenzie B.S., Blumenschein W.M., Mattson J.D., et al. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nature Immunology 2007, 8:950-957.
-
(2007)
Nature Immunology
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
-
16
-
-
34548125305
-
Interleukins 1[beta] and 6 but not transforming growth factor-[beta] are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez E.V., Napolitani G., Lanzavecchia A., Sallusto F. Interleukins 1[beta] and 6 but not transforming growth factor-[beta] are essential for the differentiation of interleukin 17-producing human T helper cells. Nature Immunology 2007, 8:942-949.
-
(2007)
Nature Immunology
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
17
-
-
47549112840
-
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
-
Yang L., Anderson D.E., Baecher-Allan C., Hastings W.D., Bettelli E., Oukka M., et al. IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008, 454:350-352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
Hastings, W.D.4
Bettelli, E.5
Oukka, M.6
-
18
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua D.J., Sherlock J., Chen Y., Murphy C.A., Joyce B., Seymour B., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003, 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
-
19
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. Journal of Experimental Medicine 2005, 201:233-240.
-
(2005)
Journal of Experimental Medicine
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
-
20
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez E.V., Rivino L., Geginat J., Jarrossay D., Gattorno M., Lanzavecchia A., et al. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nature Immunology 2007, 8:639-646.
-
(2007)
Nature Immunology
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
-
21
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato F., Cosmi L., Santarlasci V., Maggi L., Liotta F., Mazzinghi B., et al. Phenotypic and functional features of human Th17 cells. Journal of Experimental Medicine 2007, 204:1849-1861.
-
(2007)
Journal of Experimental Medicine
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
-
22
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota K., Yoshitomi H., Hashimoto M., Maeda S., Teradaira S., Sugimoto N., et al. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. Journal of Experimental Medicine 2007, 204:2803-2812.
-
(2007)
Journal of Experimental Medicine
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
Yoshitomi, H.2
Hashimoto, M.3
Maeda, S.4
Teradaira, S.5
Sugimoto, N.6
-
23
-
-
54949139265
-
The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation
-
Annunziato F., Cosmi L., Liotta F., Maggi E., Romagnani S. The phenotype of human Th17 cells and their precursors, the cytokines that mediate their differentiation and the role of Th17 cells in inflammation. International Immunology 2008, 20:1361-1368.
-
(2008)
International Immunology
, vol.20
, pp. 1361-1368
-
-
Annunziato, F.1
Cosmi, L.2
Liotta, F.3
Maggi, E.4
Romagnani, S.5
-
24
-
-
59649091305
-
CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells
-
Kleinewietfeld M., Starke M., Di Mitri D., Borsellino G., Battistini L., Rotzschke O., et al. CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells. Blood 2009, 113:827-836.
-
(2009)
Blood
, vol.113
, pp. 827-836
-
-
Kleinewietfeld, M.1
Starke, M.2
Di Mitri, D.3
Borsellino, G.4
Battistini, L.5
Rotzschke, O.6
-
25
-
-
72649083022
-
Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression
-
Brucklacher-Waldert V., Steinbach K., Lioznov M., Kolster M., Holscher C., Tolosa E. Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression. Journal of Immunology 2009, 183:5494-5501.
-
(2009)
Journal of Immunology
, vol.183
, pp. 5494-5501
-
-
Brucklacher-Waldert, V.1
Steinbach, K.2
Lioznov, M.3
Kolster, M.4
Holscher, C.5
Tolosa, E.6
-
26
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
Ivanov I.I., Atarashi K., Manel N., Brodie E.L., Shima T., Karaoz U., et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009, 139:485-498.
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
Brodie, E.L.4
Shima, T.5
Karaoz, U.6
-
27
-
-
84862657675
-
Regulation of epithelial immunity by IL-17 family cytokines
-
Pappu R., Rutz S., Ouyang W. Regulation of epithelial immunity by IL-17 family cytokines. Trends in Immunology 2012, 33:343-349.
-
(2012)
Trends in Immunology
, vol.33
, pp. 343-349
-
-
Pappu, R.1
Rutz, S.2
Ouyang, W.3
-
28
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang W., Kolls J.K., Zheng Y. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity 2008, 28:454-467.
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
29
-
-
79951743212
-
Functional specialization of interleukin-17 family members
-
Iwakura Y., Ishigame H., Saijo S., Nakae S. Functional specialization of interleukin-17 family members. Immunity 2011, 34:149-162.
-
(2011)
Immunity
, vol.34
, pp. 149-162
-
-
Iwakura, Y.1
Ishigame, H.2
Saijo, S.3
Nakae, S.4
-
30
-
-
84871321329
-
Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis
-
Puel A., Cypowyj S., Marodi L., Abel L., Picard C., Casanova J.L. Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis. Current Opinion in Allergy and Clinical Immunology 2012, 12:616-622.
-
(2012)
Current Opinion in Allergy and Clinical Immunology
, vol.12
, pp. 616-622
-
-
Puel, A.1
Cypowyj, S.2
Marodi, L.3
Abel, L.4
Picard, C.5
Casanova, J.L.6
-
31
-
-
41449110468
-
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
-
Milner J.D., Brenchley J.M., Laurence A., Freeman A.F., Hill B.J., Elias K.M., et al. Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature 2008, 452:773-776.
-
(2008)
Nature
, vol.452
, pp. 773-776
-
-
Milner, J.D.1
Brenchley, J.M.2
Laurence, A.3
Freeman, A.F.4
Hill, B.J.5
Elias, K.M.6
-
32
-
-
46949089128
-
Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3
-
Ma C.S., Chew G.Y., Simpson N., Priyadarshi A., Wong M., Grimbacher B., et al. Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. Journal of Experimental Medicine 2008, 205:1551-1557.
-
(2008)
Journal of Experimental Medicine
, vol.205
, pp. 1551-1557
-
-
Ma, C.S.1
Chew, G.Y.2
Simpson, N.3
Priyadarshi, A.4
Wong, M.5
Grimbacher, B.6
-
33
-
-
79961154447
-
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis
-
Liu L., Okada S., Kong X.F., Kreins A.Y., Cypowyj S., Abhyankar A., et al. Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis. Journal of Experimental Medicine 2011, 208:1635-1648.
-
(2011)
Journal of Experimental Medicine
, vol.208
, pp. 1635-1648
-
-
Liu, L.1
Okada, S.2
Kong, X.F.3
Kreins, A.Y.4
Cypowyj, S.5
Abhyankar, A.6
-
34
-
-
79960094057
-
STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis
-
van de Veerdonk F.L., Plantinga T.S., Hoischen A., Smeekens S.P., Joosten L.A., Gilissen C., et al. STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. New England Journal of Medicine 2011, 365:54-61.
-
(2011)
New England Journal of Medicine
, vol.365
, pp. 54-61
-
-
van de Veerdonk, F.L.1
Plantinga, T.S.2
Hoischen, A.3
Smeekens, S.P.4
Joosten, L.A.5
Gilissen, C.6
-
36
-
-
56349140640
-
Myelin proteolipid protein: an effective autoantigen and target of autoimmunity in multiple sclerosis
-
Greer J.M., Pender M.P. Myelin proteolipid protein: an effective autoantigen and target of autoimmunity in multiple sclerosis. Journal of Autoimmunity 2008, 31:281-287.
-
(2008)
Journal of Autoimmunity
, vol.31
, pp. 281-287
-
-
Greer, J.M.1
Pender, M.P.2
-
37
-
-
79960536431
-
Increased frequencies of myelin oligodendrocyte glycoprotein/MHC class II-binding CD4 cells in patients with multiple sclerosis
-
Raddassi K., Kent S.C., Yang J., Bourcier K., Bradshaw E.M., Seyfert-Margolis V., et al. Increased frequencies of myelin oligodendrocyte glycoprotein/MHC class II-binding CD4 cells in patients with multiple sclerosis. Journal of Immunology 2011, 187:1039-1046.
-
(2011)
Journal of Immunology
, vol.187
, pp. 1039-1046
-
-
Raddassi, K.1
Kent, S.C.2
Yang, J.3
Bourcier, K.4
Bradshaw, E.M.5
Seyfert-Margolis, V.6
-
38
-
-
79956116032
-
RORgammat drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
-
Codarri L., Gyulveszi G., Tosevski V., Hesske L., Fontana A., Magnenat L., et al. RORgammat drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation. Nature Immunology 2011, 12:560-567.
-
(2011)
Nature Immunology
, vol.12
, pp. 560-567
-
-
Codarri, L.1
Gyulveszi, G.2
Tosevski, V.3
Hesske, L.4
Fontana, A.5
Magnenat, L.6
-
39
-
-
79956152607
-
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
-
El-Behi M., Ciric B., Dai H., Yan Y., Cullimore M., Safavi F., et al. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF. Nature Immunology 2011, 12:568-575.
-
(2011)
Nature Immunology
, vol.12
, pp. 568-575
-
-
El-Behi, M.1
Ciric, B.2
Dai, H.3
Yan, Y.4
Cullimore, M.5
Safavi, F.6
-
40
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius D., Kivisakk P., He B., Kostulas N., Ozenci V., Fredrikson S., et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Multiple Sclerosis 1999, 5:101-104.
-
(1999)
Multiple Sclerosis
, vol.5
, pp. 101-104
-
-
Matusevicius, D.1
Kivisakk, P.2
He, B.3
Kostulas, N.4
Ozenci, V.5
Fredrikson, S.6
-
41
-
-
34948909646
-
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
-
Kebir H., Kreymborg K., Ifergan I., Dodelet-Devillers A., Cayrol R., Bernard M., et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nature Medicine 2007, 13:1173-1175.
-
(2007)
Nature Medicine
, vol.13
, pp. 1173-1175
-
-
Kebir, H.1
Kreymborg, K.2
Ifergan, I.3
Dodelet-Devillers, A.4
Cayrol, R.5
Bernard, M.6
-
42
-
-
39849101009
-
Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets
-
Han M.H., Hwang S.I., Roy D.B., Lundgren D.H., Price J.V., Ousman S.S., et al. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature 2008, 451:1076-1081.
-
(2008)
Nature
, vol.451
, pp. 1076-1081
-
-
Han, M.H.1
Hwang, S.I.2
Roy, D.B.3
Lundgren, D.H.4
Price, J.V.5
Ousman, S.S.6
-
43
-
-
72649089874
-
Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis
-
Brucklacher-Waldert V., Stuerner K., Kolster M., Wolthausen J., Tolosa E. Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis. Brain: A Journal of Neurology 2009, 132:3329-3341.
-
(2009)
Brain: A Journal of Neurology
, vol.132
, pp. 3329-3341
-
-
Brucklacher-Waldert, V.1
Stuerner, K.2
Kolster, M.3
Wolthausen, J.4
Tolosa, E.5
-
44
-
-
79955643472
-
Increased memory Th17 cells in patients with neuromyelitis optica and multiple sclerosis
-
Li Y., Wang H., Long Y., Lu Z., Hu X. Increased memory Th17 cells in patients with neuromyelitis optica and multiple sclerosis. Journal of Neuroimmunology 2011, 234:155-160.
-
(2011)
Journal of Neuroimmunology
, vol.234
, pp. 155-160
-
-
Li, Y.1
Wang, H.2
Long, Y.3
Lu, Z.4
Hu, X.5
-
45
-
-
47249128991
-
Th17 cells in human disease
-
Tesmer L.A., Lundy S.K., Sarkar S., Fox D.A. Th17 cells in human disease. Immunological Reviews 2008, 223:87-113.
-
(2008)
Immunological Reviews
, vol.223
, pp. 87-113
-
-
Tesmer, L.A.1
Lundy, S.K.2
Sarkar, S.3
Fox, D.A.4
-
46
-
-
65249175159
-
C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
-
Reboldi A., Coisne C., Baumjohann D., Benvenuto F., Bottinelli D., Lira S., et al. C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nature Immunology 2009, 10:514-523.
-
(2009)
Nature Immunology
, vol.10
, pp. 514-523
-
-
Reboldi, A.1
Coisne, C.2
Baumjohann, D.3
Benvenuto, F.4
Bottinelli, D.5
Lira, S.6
-
47
-
-
79955636935
-
IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease
-
Zepp J., Wu L., Li X. IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease. Trends in Immunology 2011, 32:232-239.
-
(2011)
Trends in Immunology
, vol.32
, pp. 232-239
-
-
Zepp, J.1
Wu, L.2
Li, X.3
-
48
-
-
77950349016
-
Th17 and regulatory T cells in mediating and restraining inflammation
-
Littman D.R., Rudensky A.Y. Th17 and regulatory T cells in mediating and restraining inflammation. Cell 2010, 140:845-858.
-
(2010)
Cell
, vol.140
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
49
-
-
67349250428
-
The gut microbiota shapes intestinal immune responses during health and disease
-
Round J.L., Mazmanian S.K. The gut microbiota shapes intestinal immune responses during health and disease. Nature Reviews Immunology 2009, 9:313-323.
-
(2009)
Nature Reviews Immunology
, vol.9
, pp. 313-323
-
-
Round, J.L.1
Mazmanian, S.K.2
-
50
-
-
53649100675
-
ATP drives lamina propria TH17 cell differentiation
-
Atarashi K., Nishimura J., Shima T., Umesaki Y., Yamamoto M., Onoue M., et al. ATP drives lamina propria TH17 cell differentiation. Nature 2008, 455:808-812.
-
(2008)
Nature
, vol.455
, pp. 808-812
-
-
Atarashi, K.1
Nishimura, J.2
Shima, T.3
Umesaki, Y.4
Yamamoto, M.5
Onoue, M.6
-
51
-
-
79952748674
-
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
-
Lee Y.K., Menezes J.S., Umesaki Y., Mazmanian S.K. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America 2011, 108(Suppl. 1):4615-4622.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.SUPPL. 1
, pp. 4615-4622
-
-
Lee, Y.K.1
Menezes, J.S.2
Umesaki, Y.3
Mazmanian, S.K.4
-
52
-
-
81855167104
-
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
-
Berer K., Mues M., Koutrolos M., Rasbi Z.A., Boziki M., Johner C., et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 2011, 479:538-541.
-
(2011)
Nature
, vol.479
, pp. 538-541
-
-
Berer, K.1
Mues, M.2
Koutrolos, M.3
Rasbi, Z.A.4
Boziki, M.5
Johner, C.6
-
53
-
-
0028340944
-
Hypertonic saline enhances cellular immune function
-
Junger W.G., Liu F.C., Loomis W.H., Hoyt D.B. Hypertonic saline enhances cellular immune function. Circulatory Shock 1994, 42:190-196.
-
(1994)
Circulatory Shock
, vol.42
, pp. 190-196
-
-
Junger, W.G.1
Liu, F.C.2
Loomis, W.H.3
Hoyt, D.B.4
-
54
-
-
3242674944
-
NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment
-
Go W.Y., Liu X., Roti M.A., Liu F., Ho S.N. NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:10673-10678.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 10673-10678
-
-
Go, W.Y.1
Liu, X.2
Roti, M.A.3
Liu, F.4
Ho, S.N.5
-
55
-
-
66749106368
-
Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism
-
Machnik A., Neuhofer W., Jantsch J., Dahlmann A., Tammela T., Machura K., et al. Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C-dependent buffering mechanism. Nature Medicine 2009, 15:545-552.
-
(2009)
Nature Medicine
, vol.15
, pp. 545-552
-
-
Machnik, A.1
Neuhofer, W.2
Jantsch, J.3
Dahlmann, A.4
Tammela, T.5
Machura, K.6
-
56
-
-
84879616239
-
Immune cells control skin lymphatic electrolyte homeostasis and blood pressure
-
Wiig H., Schroder A., Neuhofer W., Jantsch J., Kopp C., Karlsen T.V., et al. Immune cells control skin lymphatic electrolyte homeostasis and blood pressure. Journal of Clinical Investigation 2013, 123:2803-2815.
-
(2013)
Journal of Clinical Investigation
, vol.123
, pp. 2803-2815
-
-
Wiig, H.1
Schroder, A.2
Neuhofer, W.3
Jantsch, J.4
Kopp, C.5
Karlsen, T.V.6
-
57
-
-
77149143546
-
Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats
-
Machnik A., Dahlmann A., Kopp C., Goss J., Wagner H., van Rooijen N., et al. Mononuclear phagocyte system depletion blocks interstitial tonicity-responsive enhancer binding protein/vascular endothelial growth factor C expression and induces salt-sensitive hypertension in rats. Hypertension 2010, 55:755-761.
-
(2010)
Hypertension
, vol.55
, pp. 755-761
-
-
Machnik, A.1
Dahlmann, A.2
Kopp, C.3
Goss, J.4
Wagner, H.5
van Rooijen, N.6
-
58
-
-
84876787121
-
Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells
-
Kleinewietfeld M., Manzel A., Titze J., Kvakan H., Yosef N., Linker R.A., et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature 2013, 496:518-522.
-
(2013)
Nature
, vol.496
, pp. 518-522
-
-
Kleinewietfeld, M.1
Manzel, A.2
Titze, J.3
Kvakan, H.4
Yosef, N.5
Linker, R.A.6
-
59
-
-
84876798411
-
Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1
-
Wu C., Yosef N., Thalhamer T., Zhu C., Xiao S., Kishi Y., et al. Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Nature 2013, 496:513-517.
-
(2013)
Nature
, vol.496
, pp. 513-517
-
-
Wu, C.1
Yosef, N.2
Thalhamer, T.3
Zhu, C.4
Xiao, S.5
Kishi, Y.6
-
60
-
-
33746338535
-
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans
-
Roncarolo M.G., Gregori S., Battaglia M., Bacchetta R., Fleischhauer K., Levings M.K. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunological Reviews 2006, 212:28-50.
-
(2006)
Immunological Reviews
, vol.212
, pp. 28-50
-
-
Roncarolo, M.G.1
Gregori, S.2
Battaglia, M.3
Bacchetta, R.4
Fleischhauer, K.5
Levings, M.K.6
-
61
-
-
77954141914
-
FOXP3+ regulatory T cells in the human immune system
-
Sakaguchi S., Miyara M., Costantino C.M., Hafler D.A. FOXP3+ regulatory T cells in the human immune system. Nature Reviews Immunology 2010, 10:490-500.
-
(2010)
Nature Reviews Immunology
, vol.10
, pp. 490-500
-
-
Sakaguchi, S.1
Miyara, M.2
Costantino, C.M.3
Hafler, D.A.4
-
62
-
-
0035413350
-
CD4+CD25 high regulatory cells in human peripheral blood
-
Baecher-Allan C., Brown J.A., Freeman G.J., Hafler D.A. CD4+CD25 high regulatory cells in human peripheral blood. Journal of Immunology 2001, 167:1245-1253.
-
(2001)
Journal of Immunology
, vol.167
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
63
-
-
16844363097
-
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot J.D., Rudensky A.Y. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nature Immunology 2005, 6:331-337.
-
(2005)
Nature Immunology
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
64
-
-
34548755672
-
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
-
Baron U., Floess S., Wieczorek G., Baumann K., Grutzkau A., Dong J., et al. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. European Journal of Immunology 2007, 37:2378-2389.
-
(2007)
European Journal of Immunology
, vol.37
, pp. 2378-2389
-
-
Baron, U.1
Floess, S.2
Wieczorek, G.3
Baumann, K.4
Grutzkau, A.5
Dong, J.6
-
65
-
-
84875498856
-
Development and maintenance of regulatory T cells
-
Ohkura N., Kitagawa Y., Sakaguchi S. Development and maintenance of regulatory T cells. Immunity 2013, 38:414-423.
-
(2013)
Immunity
, vol.38
, pp. 414-423
-
-
Ohkura, N.1
Kitagawa, Y.2
Sakaguchi, S.3
-
66
-
-
32944456599
-
Cd4+Cd25+ regulatory T cells and their therapeutic potential
-
Randolph D.A., Fathman C.G. Cd4+Cd25+ regulatory T cells and their therapeutic potential. Annual Review of Medicine 2006, 57:381-402.
-
(2006)
Annual Review of Medicine
, vol.57
, pp. 381-402
-
-
Randolph, D.A.1
Fathman, C.G.2
-
68
-
-
39449126502
-
The Foxp3(+) regulatory T cell: a jack of all trades, master of regulation
-
Tang Q.Z., Bluestone J.A. The Foxp3(+) regulatory T cell: a jack of all trades, master of regulation. Nature Immunology 2008, 9:239-244.
-
(2008)
Nature Immunology
, vol.9
, pp. 239-244
-
-
Tang, Q.Z.1
Bluestone, J.A.2
-
69
-
-
0142250482
-
Regulatory T cells under scrutiny
-
Bach J.F. Regulatory T cells under scrutiny. Nature Reviews Immunology 2003, 3:189-198.
-
(2003)
Nature Reviews Immunology
, vol.3
, pp. 189-198
-
-
Bach, J.F.1
-
70
-
-
49849094011
-
Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other
-
Horwitz D.A., Zheng S.G., Gray J.D. Natural and TGF-beta-induced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other. Trends in Immunology 2008, 29:429-435.
-
(2008)
Trends in Immunology
, vol.29
, pp. 429-435
-
-
Horwitz, D.A.1
Zheng, S.G.2
Gray, J.D.3
-
71
-
-
34247277666
-
Foxp3 in control of the regulatory T cell lineage
-
Zheng Y., Rudensky A.Y. Foxp3 in control of the regulatory T cell lineage. Nature Immunology 2007, 8:457-462.
-
(2007)
Nature Immunology
, vol.8
, pp. 457-462
-
-
Zheng, Y.1
Rudensky, A.Y.2
-
72
-
-
15944425718
-
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset
-
Kleinewietfeld M., Puentes F., Borsellino G., Battistini L., Rotzschke O., Falk K. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood 2005, 105:2877-2886.
-
(2005)
Blood
, vol.105
, pp. 2877-2886
-
-
Kleinewietfeld, M.1
Puentes, F.2
Borsellino, G.3
Battistini, L.4
Rotzschke, O.5
Falk, K.6
-
73
-
-
34547098277
-
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
-
Borsellino G., Kleinewietfeld M., Di Mitri D., Sternjak A., Diamantini A., Giometto R., et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood 2007, 110:1225-1232.
-
(2007)
Blood
, vol.110
, pp. 1225-1232
-
-
Borsellino, G.1
Kleinewietfeld, M.2
Di Mitri, D.3
Sternjak, A.4
Diamantini, A.5
Giometto, R.6
-
74
-
-
33645778289
-
MHC class II expression identifies functionally distinct human regulatory T cells
-
Baecher-Allan C., Wolf E., Hafler D.A. MHC class II expression identifies functionally distinct human regulatory T cells. Journal of Immunology 2006, 176:4622-4631.
-
(2006)
Journal of Immunology
, vol.176
, pp. 4622-4631
-
-
Baecher-Allan, C.1
Wolf, E.2
Hafler, D.A.3
-
75
-
-
34548721641
-
Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis
-
Haas J., Fritzsching B., Trubswetter P., Korporal M., Milkova L., Fritz B., et al. Prevalence of newly generated naive regulatory T cells (Treg) is critical for Treg suppressive function and determines Treg dysfunction in multiple sclerosis. Journal of Immunology 2007, 179:1322-1330.
-
(2007)
Journal of Immunology
, vol.179
, pp. 1322-1330
-
-
Haas, J.1
Fritzsching, B.2
Trubswetter, P.3
Korporal, M.4
Milkova, L.5
Fritz, B.6
-
76
-
-
33751175422
-
Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death
-
Fritzsching B., Oberle N., Pauly E., Geffers R., Buer J., Poschl J., et al. Naive regulatory T cells: a novel subpopulation defined by resistance toward CD95L-mediated cell death. Blood 2006, 108:3371-3378.
-
(2006)
Blood
, vol.108
, pp. 3371-3378
-
-
Fritzsching, B.1
Oberle, N.2
Pauly, E.3
Geffers, R.4
Buer, J.5
Poschl, J.6
-
77
-
-
81055148068
-
CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells
-
Solstad T., Bains S.J., Landskron J., Aandahl E.M., Thiede B., Tasken K., et al. CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells. Blood 2011, 118:5141-5151.
-
(2011)
Blood
, vol.118
, pp. 5141-5151
-
-
Solstad, T.1
Bains, S.J.2
Landskron, J.3
Aandahl, E.M.4
Thiede, B.5
Tasken, K.6
-
78
-
-
44649189089
-
Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery
-
Ito T., Hanabuchi S., Wang Y.H., Park W.R., Arima K., Bover L., et al. Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 2008, 28:870-880.
-
(2008)
Immunity
, vol.28
, pp. 870-880
-
-
Ito, T.1
Hanabuchi, S.2
Wang, Y.H.3
Park, W.R.4
Arima, K.5
Bover, L.6
-
79
-
-
20344392877
-
Migration rules: functional properties of naive and effector/memory-like regulatory T cell subsets
-
Huehn J., Siegmund K., Hamann A. Migration rules: functional properties of naive and effector/memory-like regulatory T cell subsets. Current Topics in Microbiology and Immunology 2005, 293:89-114.
-
(2005)
Current Topics in Microbiology and Immunology
, vol.293
, pp. 89-114
-
-
Huehn, J.1
Siegmund, K.2
Hamann, A.3
-
80
-
-
27744528888
-
Homing to suppress: address codes for Treg migration
-
Huehn J., Hamann A. Homing to suppress: address codes for Treg migration. Trends in Immunology 2005, 26:632-636.
-
(2005)
Trends in Immunology
, vol.26
, pp. 632-636
-
-
Huehn, J.1
Hamann, A.2
-
81
-
-
84355162741
-
Response to self antigen imprints regulatory memory in tissues
-
Rosenblum M.D., Gratz I.K., Paw J.S., Lee K., Marshak-Rothstein A., Abbas A.K. Response to self antigen imprints regulatory memory in tissues. Nature 2011, 480:538-542.
-
(2011)
Nature
, vol.480
, pp. 538-542
-
-
Rosenblum, M.D.1
Gratz, I.K.2
Paw, J.S.3
Lee, K.4
Marshak-Rothstein, A.5
Abbas, A.K.6
-
83
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou I., von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. Journal of Experimental Medicine 2004, 199:1401-1408.
-
(2004)
Journal of Experimental Medicine
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
von Boehmer, H.2
-
84
-
-
1342308180
-
Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease
-
Ling E.M., Smith T., Nguyen X.D., Pridgeon C., Dallman M., Arbery J., et al. Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease. Lancet 2004, 363:608-615.
-
(2004)
Lancet
, vol.363
, pp. 608-615
-
-
Ling, E.M.1
Smith, T.2
Nguyen, X.D.3
Pridgeon, C.4
Dallman, M.5
Arbery, J.6
-
85
-
-
33746356813
-
Human regulatory T cells and their role in autoimmune disease
-
Baecher-Allan C., Hafler D.A. Human regulatory T cells and their role in autoimmune disease. Immunological Reviews 2006, 212:203-216.
-
(2006)
Immunological Reviews
, vol.212
, pp. 203-216
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
89
-
-
65249155425
-
The role of the CD58 locus in multiple sclerosis
-
De Jager P.L., Baecher-Allan C., Maier L.M., Arthur A.T., Ottoboni L., Barcellos L., et al. The role of the CD58 locus in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:5264-5269.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 5264-5269
-
-
De Jager, P.L.1
Baecher-Allan, C.2
Maier, L.M.3
Arthur, A.T.4
Ottoboni, L.5
Barcellos, L.6
-
91
-
-
84862733981
-
Regulatory T cells in the central nervous system
-
Lowther D.E., Hafler D.A. Regulatory T cells in the central nervous system. Immunological Reviews 2012, 248:156-169.
-
(2012)
Immunological Reviews
, vol.248
, pp. 156-169
-
-
Lowther, D.E.1
Hafler, D.A.2
-
92
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
Mazmanian S.K., Round J.L., Kasper D.L. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008, 453:620-625.
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
94
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
Atarashi K., Tanoue T., Shima T., Imaoka A., Kuwahara T., Momose Y., et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011, 331:337-341.
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
Imaoka, A.4
Kuwahara, T.5
Momose, Y.6
-
95
-
-
77955913743
-
A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease
-
Ochoa-Reparaz J., Mielcarz D.W., Wang Y., Begum-Haque S., Dasgupta S., Kasper D.L., et al. A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease. Mucosal Immunology 2010, 3:487-495.
-
(2010)
Mucosal Immunology
, vol.3
, pp. 487-495
-
-
Ochoa-Reparaz, J.1
Mielcarz, D.W.2
Wang, Y.3
Begum-Haque, S.4
Dasgupta, S.5
Kasper, D.L.6
-
96
-
-
77958119730
-
Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
-
Ochoa-Reparaz J., Mielcarz D.W., Ditrio L.E., Burroughs A.R., Begum-Haque S., Dasgupta S., et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. Journal of Immunology 2010, 185:4101-4108.
-
(2010)
Journal of Immunology
, vol.185
, pp. 4101-4108
-
-
Ochoa-Reparaz, J.1
Mielcarz, D.W.2
Ditrio, L.E.3
Burroughs, A.R.4
Begum-Haque, S.5
Dasgupta, S.6
-
97
-
-
84881477044
-
Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
-
Atarashi K., Tanoue T., Oshima K., Suda W., Nagano Y., Nishikawa H., et al. Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota. Nature 2013, 500:232-236.
-
(2013)
Nature
, vol.500
, pp. 232-236
-
-
Atarashi, K.1
Tanoue, T.2
Oshima, K.3
Suda, W.4
Nagano, Y.5
Nishikawa, H.6
-
98
-
-
43449135305
-
TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function
-
Zhou L., Lopes J.E., Chong M.M., Ivanov I.I., Min R., Victora G.D., et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature 2008, 453:236-240.
-
(2008)
Nature
, vol.453
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
Ivanov, I.I.4
Min, R.5
Victora, G.D.6
-
99
-
-
44449131480
-
Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3
-
Du J., Huang C., Zhou B., Ziegler S.F. Isoform-specific inhibition of ROR alpha-mediated transcriptional activation by human FOXP3. Journal of Immunology 2008, 180:4785-4792.
-
(2008)
Journal of Immunology
, vol.180
, pp. 4785-4792
-
-
Du, J.1
Huang, C.2
Zhou, B.3
Ziegler, S.F.4
-
100
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007, 317:256-260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
-
101
-
-
42649106556
-
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
-
Veldhoen M., Hirota K., Westendorf A.M., Buer J., Dumoutier L., Renauld J.C., et al. The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature 2008, 453:106-109.
-
(2008)
Nature
, vol.453
, pp. 106-109
-
-
Veldhoen, M.1
Hirota, K.2
Westendorf, A.M.3
Buer, J.4
Dumoutier, L.5
Renauld, J.C.6
-
102
-
-
42649095378
-
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
-
Quintana F.J., Basso A.S., Iglesias A.H., Korn T., Farez M.F., Bettelli E., et al. Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor. Nature 2008, 453:65-71.
-
(2008)
Nature
, vol.453
, pp. 65-71
-
-
Quintana, F.J.1
Basso, A.S.2
Iglesias, A.H.3
Korn, T.4
Farez, M.F.5
Bettelli, E.6
-
103
-
-
80052277906
-
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
-
Dang E.V., Barbi J., Yang H.Y., Jinasena D., Yu H., Zheng Y., et al. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell 2011, 146:772-784.
-
(2011)
Cell
, vol.146
, pp. 772-784
-
-
Dang, E.V.1
Barbi, J.2
Yang, H.Y.3
Jinasena, D.4
Yu, H.5
Zheng, Y.6
-
104
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., Wang R., Huang G., Vogel P., Neale G., Green D.R., et al. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. Journal of Experimental Medicine 2011, 208:1367-1376.
-
(2011)
Journal of Experimental Medicine
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
-
105
-
-
80955131364
-
Romance of the three kingdoms: RORgammat allies with HIF1alpha against FoxP3 in regulating T cell metabolism and differentiation
-
Tsun A., Chen Z., Li B. Romance of the three kingdoms: RORgammat allies with HIF1alpha against FoxP3 in regulating T cell metabolism and differentiation. Protein & Cell 2011, 2:778-781.
-
(2011)
Protein & Cell
, vol.2
, pp. 778-781
-
-
Tsun, A.1
Chen, Z.2
Li, B.3
-
106
-
-
84880011577
-
Microbial reprogramming inhibits Western diet-associated obesity
-
Poutahidis T., Kleinewietfeld M., Smillie C., Levkovich T., Perrotta A., Bhela S., et al. Microbial reprogramming inhibits Western diet-associated obesity. PLOS ONE 2013, 8:e68596.
-
(2013)
PLOS ONE
, vol.8
-
-
Poutahidis, T.1
Kleinewietfeld, M.2
Smillie, C.3
Levkovich, T.4
Perrotta, A.5
Bhela, S.6
-
108
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee Y.K., Turner H., Maynard C.L., Oliver J.R., Chen D., Elson C.O., et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009, 30:92-107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
Elson, C.O.6
-
110
-
-
79951677394
-
Fate mapping of IL-17-producing T cells in inflammatory responses
-
Hirota K., Duarte J.H., Veldhoen M., Hornsby E., Li Y., Cua D.J., et al. Fate mapping of IL-17-producing T cells in inflammatory responses. Nature Immunology 2011, 12:255-263.
-
(2011)
Nature Immunology
, vol.12
, pp. 255-263
-
-
Hirota, K.1
Duarte, J.H.2
Veldhoen, M.3
Hornsby, E.4
Li, Y.5
Cua, D.J.6
-
111
-
-
84866749073
-
Defining the human T helper 17 cell phenotype
-
Annunziato F., Cosmi L., Liotta F., Maggi E., Romagnani S. Defining the human T helper 17 cell phenotype. Trends in Immunology 2012, 33:505-512.
-
(2012)
Trends in Immunology
, vol.33
, pp. 505-512
-
-
Annunziato, F.1
Cosmi, L.2
Liotta, F.3
Maggi, E.4
Romagnani, S.5
-
112
-
-
84871312272
-
Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells
-
Maggi L., Santarlasci V., Capone M., Rossi M.C., Querci V., Mazzoni A., et al. Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells. European Journal of Immunology 2012, 42:3180-3188.
-
(2012)
European Journal of Immunology
, vol.42
, pp. 3180-3188
-
-
Maggi, L.1
Santarlasci, V.2
Capone, M.3
Rossi, M.C.4
Querci, V.5
Mazzoni, A.6
-
113
-
-
77958584113
-
Generation of pathogenic T(H)17 cells in the absence of TGF-beta signalling
-
Ghoreschi K., Laurence A., Yang X.P., Tato C.M., McGeachy M.J., Konkel J.E., et al. Generation of pathogenic T(H)17 cells in the absence of TGF-beta signalling. Nature 2010, 467:967-971.
-
(2010)
Nature
, vol.467
, pp. 967-971
-
-
Ghoreschi, K.1
Laurence, A.2
Yang, X.P.3
Tato, C.M.4
McGeachy, M.J.5
Konkel, J.E.6
-
114
-
-
84866532132
-
Induction and molecular signature of pathogenic TH17 cells
-
Lee Y., Awasthi A., Yosef N., Quintana F.J., Xiao S., Peters A., et al. Induction and molecular signature of pathogenic TH17 cells. Nature Immunology 2012, 13:991-999.
-
(2012)
Nature Immunology
, vol.13
, pp. 991-999
-
-
Lee, Y.1
Awasthi, A.2
Yosef, N.3
Quintana, F.J.4
Xiao, S.5
Peters, A.6
-
115
-
-
84860241847
-
Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta
-
Zielinski C.E., Mele F., Aschenbrenner D., Jarrossay D., Ronchi F., Gattorno M., et al. Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature 2012, 484:514-518.
-
(2012)
Nature
, vol.484
, pp. 514-518
-
-
Zielinski, C.E.1
Mele, F.2
Aschenbrenner, D.3
Jarrossay, D.4
Ronchi, F.5
Gattorno, M.6
-
116
-
-
79960919901
-
Control of TH17 cells occurs in the small intestine
-
Esplugues E., Huber S., Gagliani N., Hauser A.E., Town T., Wan Y.Y., et al. Control of TH17 cells occurs in the small intestine. Nature 2011, 475:514-518.
-
(2011)
Nature
, vol.475
, pp. 514-518
-
-
Esplugues, E.1
Huber, S.2
Gagliani, N.3
Hauser, A.E.4
Town, T.5
Wan, Y.Y.6
-
117
-
-
84856022450
-
Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection
-
Panzer M., Sitte S., Wirth S., Drexler I., Sparwasser T., Voehringer D. Rapid in vivo conversion of effector T cells into Th2 cells during helminth infection. Journal of Immunology 2012, 188:615-623.
-
(2012)
Journal of Immunology
, vol.188
, pp. 615-623
-
-
Panzer, M.1
Sitte, S.2
Wirth, S.3
Drexler, I.4
Sparwasser, T.5
Voehringer, D.6
-
118
-
-
84876889786
-
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease
-
Hirahara K., Poholek A., Vahedi G., Laurence A., Kanno Y., Milner J.D., et al. Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease. Journal of allergy and clinical immunology 2013, 131:1276-1287.
-
(2013)
Journal of allergy and clinical immunology
, vol.131
, pp. 1276-1287
-
-
Hirahara, K.1
Poholek, A.2
Vahedi, G.3
Laurence, A.4
Kanno, Y.5
Milner, J.D.6
-
119
-
-
67049168780
-
Plasticity of CD4(+) FoxP3(+) T cells
-
Zhou X., Bailey-Bucktrout S., Jeker L.T., Bluestone J.A. Plasticity of CD4(+) FoxP3(+) T cells. Current Opinion in Immunology 2009, 21:281-285.
-
(2009)
Current Opinion in Immunology
, vol.21
, pp. 281-285
-
-
Zhou, X.1
Bailey-Bucktrout, S.2
Jeker, L.T.3
Bluestone, J.A.4
-
120
-
-
9244223651
-
Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity
-
Stock P., Akbari O., Berry G., Freeman G.J., Dekruyff R.H., Umetsu D.T. Induction of T helper type 1-like regulatory cells that express Foxp3 and protect against airway hyper-reactivity. Nature Immunology 2004, 5:1149-1156.
-
(2004)
Nature Immunology
, vol.5
, pp. 1149-1156
-
-
Stock, P.1
Akbari, O.2
Berry, G.3
Freeman, G.J.4
Dekruyff, R.H.5
Umetsu, D.T.6
-
121
-
-
33847125247
-
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
-
Wan Y.Y., Flavell R.A. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 2007, 445:766-770.
-
(2007)
Nature
, vol.445
, pp. 766-770
-
-
Wan, Y.Y.1
Flavell, R.A.2
-
122
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams L.M., Rudensky A.Y. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nature Immunology 2007, 8:277-284.
-
(2007)
Nature Immunology
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
123
-
-
65449125930
-
Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
-
Duarte J.H., Zelenay S., Bergman M.L., Martins A.C., Demengeot J. Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. European Journal of Immunology 2009, 39:948-955.
-
(2009)
European Journal of Immunology
, vol.39
, pp. 948-955
-
-
Duarte, J.H.1
Zelenay, S.2
Bergman, M.L.3
Martins, A.C.4
Demengeot, J.5
-
124
-
-
69049107358
-
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
-
Zhou X., Bailey-Bucktrout S.L., Jeker L.T., Penaranda C., Martinez-Llordella M., Ashby M., et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nature Immunology 2009, 10:1000-1007.
-
(2009)
Nature Immunology
, vol.10
, pp. 1000-1007
-
-
Zhou, X.1
Bailey-Bucktrout, S.L.2
Jeker, L.T.3
Penaranda, C.4
Martinez-Llordella, M.5
Ashby, M.6
-
125
-
-
70449532980
-
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection
-
Oldenhove G., Bouladoux N., Wohlfert E.A., Hall J.A., Chou D., Dos Santos L., et al. Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. Immunity 2009, 31:772-786.
-
(2009)
Immunity
, vol.31
, pp. 772-786
-
-
Oldenhove, G.1
Bouladoux, N.2
Wohlfert, E.A.3
Hall, J.A.4
Chou, D.5
Dos Santos, L.6
-
127
-
-
0035806244
-
Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
-
Dieckmann D., Plottner H., Berchtold S., Berger T., Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. Journal of Experimental Medicine 2001, 193:1303-1310.
-
(2001)
Journal of Experimental Medicine
, vol.193
, pp. 1303-1310
-
-
Dieckmann, D.1
Plottner, H.2
Berchtold, S.3
Berger, T.4
Schuler, G.5
-
130
-
-
33646240855
-
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development
-
Gavin M.A., Torgerson T.R., Houston E., DeRoos P., Ho W.Y., Stray-Pedersen A., et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:6659-6664.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 6659-6664
-
-
Gavin, M.A.1
Torgerson, T.R.2
Houston, E.3
DeRoos, P.4
Ho, W.Y.5
Stray-Pedersen, A.6
-
132
-
-
79955028001
-
Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
-
McClymont S.A., Putnam A.L., Lee M.R., Esensten J.H., Liu W., Hulme M.A., et al. Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. Journal of Immunology 2011, 186:3918-3926.
-
(2011)
Journal of Immunology
, vol.186
, pp. 3918-3926
-
-
McClymont, S.A.1
Putnam, A.L.2
Lee, M.R.3
Esensten, J.H.4
Liu, W.5
Hulme, M.A.6
-
133
-
-
34249799285
-
- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
-
- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. Journal of Immunology 2007, 178:6725-6729.
-
(2007)
Journal of Immunology
, vol.178
, pp. 6725-6729
-
-
Xu, L.1
Kitani, A.2
Fuss, I.3
Strober, W.4
-
134
-
-
55149094300
-
Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
-
Koenen H.J., Smeets R.L., Vink P.M., van Rijssen E., Boots A.M., Joosten I. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008, 112:2340-2352.
-
(2008)
Blood
, vol.112
, pp. 2340-2352
-
-
Koenen, H.J.1
Smeets, R.L.2
Vink, P.M.3
van Rijssen, E.4
Boots, A.M.5
Joosten, I.6
-
135
-
-
59749087126
-
DC activated via dectin-1 convert Treg into IL-17 producers
-
Osorio F., LeibundGut-Landmann S., Lochner M., Lahl K., Sparwasser T., Eberl G., et al. DC activated via dectin-1 convert Treg into IL-17 producers. European Journal of Immunology 2008, 38:3274-3281.
-
(2008)
European Journal of Immunology
, vol.38
, pp. 3274-3281
-
-
Osorio, F.1
LeibundGut-Landmann, S.2
Lochner, M.3
Lahl, K.4
Sparwasser, T.5
Eberl, G.6
-
136
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
Yang X.O., Nurieva R., Martinez G.J., Kang H.S., Chung Y., Pappu B.P., et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 2008, 29:44-56.
-
(2008)
Immunity
, vol.29
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
Kang, H.S.4
Chung, Y.5
Pappu, B.P.6
-
137
-
-
84866309651
-
Runx1 and Runx3 are involved in the generation and function of highly suppressive IL-17-producing T regulatory cells
-
Li L., Patsoukis N., Petkova V., Boussiotis V.A. Runx1 and Runx3 are involved in the generation and function of highly suppressive IL-17-producing T regulatory cells. PLoS ONE 2012, 7:e45115.
-
(2012)
PLoS ONE
, vol.7
-
-
Li, L.1
Patsoukis, N.2
Petkova, V.3
Boussiotis, V.A.4
-
138
-
-
65549088243
-
IL-17-producing human peripheral regulatory T cells retain suppressive function
-
Beriou G., Costantino C.M., Ashley C.W., Yang L., Kuchroo V.K., Baecher-Allan C., et al. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood 2009, 113:4240-4249.
-
(2009)
Blood
, vol.113
, pp. 4240-4249
-
-
Beriou, G.1
Costantino, C.M.2
Ashley, C.W.3
Yang, L.4
Kuchroo, V.K.5
Baecher-Allan, C.6
-
139
-
-
63849183918
-
Identification of IL-17-producing FOXP3+ regulatory T cells in humans
-
Voo K.S., Wang Y.H., Santori F.R., Boggiano C., Wang Y.H., Arima K., et al. Identification of IL-17-producing FOXP3+ regulatory T cells in humans. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:4793-4798.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, pp. 4793-4798
-
-
Voo, K.S.1
Wang, Y.H.2
Santori, F.R.3
Boggiano, C.4
Wang, Y.H.5
Arima, K.6
-
141
-
-
80052677833
-
TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function
-
Nyirenda M.H., Sanvito L., Darlington P.J., O'Brien K., Zhang G.X., Constantinescu C.S., et al. TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function. Journal of Immunology 2011, 187:2278-2290.
-
(2011)
Journal of Immunology
, vol.187
, pp. 2278-2290
-
-
Nyirenda, M.H.1
Sanvito, L.2
Darlington, P.J.3
O'Brien, K.4
Zhang, G.X.5
Constantinescu, C.S.6
-
143
-
-
67650351923
-
Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes
-
Sharma M.D., Hou D.Y., Liu Y., Koni P.A., Metz R., Chandler P., et al. Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes. Blood 2009, 113:6102-6111.
-
(2009)
Blood
, vol.113
, pp. 6102-6111
-
-
Sharma, M.D.1
Hou, D.Y.2
Liu, Y.3
Koni, P.A.4
Metz, R.5
Chandler, P.6
-
144
-
-
38349133347
-
Hydrolysis of extracellular ATP by CD39(+) Treg cells: context matters!
-
Kleinewietfeld M., DiMitri D., Sternjak A., Diamantini A., Borsellino G., Battistini L., et al. Hydrolysis of extracellular ATP by CD39(+) Treg cells: context matters!. Blood 2008, 111:965-966.
-
(2008)
Blood
, vol.111
, pp. 965-966
-
-
Kleinewietfeld, M.1
DiMitri, D.2
Sternjak, A.3
Diamantini, A.4
Borsellino, G.5
Battistini, L.6
-
145
-
-
84886728752
-
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39
-
Mascanfroni I.D., Yeste A., Vieira S.M., Burns E.J., Patel B., Sloma I., et al. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nature Immunology 2013.
-
(2013)
Nature Immunology
-
-
Mascanfroni, I.D.1
Yeste, A.2
Vieira, S.M.3
Burns, E.J.4
Patel, B.5
Sloma, I.6
-
146
-
-
80051801522
-
Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin
-
Bovenschen H.J., van de Kerkhof P.C., van Erp P.E., Woestenenk R., Joosten I., Koenen H.J. Foxp3+ regulatory T cells of psoriasis patients easily differentiate into IL-17A-producing cells and are found in lesional skin. Journal of Investigative Dermatology 2011, 131:1853-1860.
-
(2011)
Journal of Investigative Dermatology
, vol.131
, pp. 1853-1860
-
-
Bovenschen, H.J.1
van de Kerkhof, P.C.2
van Erp, P.E.3
Woestenenk, R.4
Joosten, I.5
Koenen, H.J.6
-
147
-
-
84874890576
-
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis
-
Singh K., Gatzka M., Peters T., Borkner L., Hainzl A., Wang H., et al. Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis. Journal of Immunology 2013, 190:2544-2553.
-
(2013)
Journal of Immunology
, vol.190
, pp. 2544-2553
-
-
Singh, K.1
Gatzka, M.2
Peters, T.3
Borkner, L.4
Hainzl, A.5
Wang, H.6
-
148
-
-
84861594192
-
Inhibition of interleukin-17 promotes differentiation of CD25(-) cells into stable T regulatory cells in patients with autoimmune hepatitis
-
e1526
-
Longhi M.S., Liberal R., Holder B., Robson S.C., Ma Y., Mieli-Vergani G., et al. Inhibition of interleukin-17 promotes differentiation of CD25(-) cells into stable T regulatory cells in patients with autoimmune hepatitis. Gastroenterology. 2012, 142:1526-1535. e1526.
-
(2012)
Gastroenterology.
, vol.142
, pp. 1526-1535
-
-
Longhi, M.S.1
Liberal, R.2
Holder, B.3
Robson, S.C.4
Ma, Y.5
Mieli-Vergani, G.6
-
149
-
-
84886242509
-
The interplay between regulatory and effector T cells in autoimmune hepatitis: implications for innovative treatment strategies
-
Muratori L., Longhi M.S. The interplay between regulatory and effector T cells in autoimmune hepatitis: implications for innovative treatment strategies. Journal of Autoimmunity 2013.
-
(2013)
Journal of Autoimmunity
-
-
Muratori, L.1
Longhi, M.S.2
-
150
-
-
84878922773
-
Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction
-
Liu X., Gao N., Li M., Xu D., Hou Y., Wang Q., et al. Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction. PLOS ONE 2013, 8:e64531.
-
(2013)
PLOS ONE
, vol.8
-
-
Liu, X.1
Gao, N.2
Li, M.3
Xu, D.4
Hou, Y.5
Wang, Q.6
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