-
1
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25)
-
Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). J. Immunol. 160, 1151-1164 (1995).
-
(1995)
J. Immunol.
, vol.160
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
2
-
-
0037364804
-
Natural versus adaptive regulatory T cells
-
Bluestone, J.A. & Abbas, A.K. Natural versus adaptive regulatory T cells. Nat. Rev. Immunol. 3, 253-257 (2003).
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 253-257
-
-
Bluestone, J.A.1
Abbas, A.K.2
-
3
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389, 737-742 (1997).
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
4
-
-
0037018104
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195, 603-616 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
5
-
-
0141678964
-
Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis
-
Bynoe, M.S., Evans, J.T., Viret, C. & Janeway, C.A.Jr. Epicutaneous immunization with autoantigenic peptides induces T suppressor cells that prevent experimental allergic encephalomyelitis. Immunity 19, 317-328 (2003).
-
(2003)
Immunity
, vol.19
, pp. 317-328
-
-
Bynoe, M.S.1
Evans, J.T.2
Viret, C.3
Janeway Jr., C.A.4
-
6
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari, O. et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 8, 1024-1032 (2002).
-
(2002)
Nat. Med.
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
-
7
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen, Y., Kuchroo, V.K., Inobe, J., Hafler, D.A. & Weiner, H.L. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265, 1237-1240 (1994 ).
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
9
-
-
0027336689
-
+ T cells through IL-12 produces by Listeria-induced macrophages
-
+ T cells through IL-12 produces by Listeria-induced macrophages. Science 260, 547-549 (1993).
-
(1993)
Science
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
-
11
-
-
0032945548
-
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
-
Hansen, G., Berry, G., DeKruyff, R.H. & Umetsu, D.T. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J. Clin. Invest. 103, 175-183 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 175-183
-
-
Hansen, G.1
Berry, G.2
DeKruyff, R.H.3
Umetsu, D.T.4
-
12
-
-
0033557718
-
Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
-
Randolph, D.A., Carruthers, C.J., Szabo, S.J., Murphy, K.M. & Chaplin, D.D. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J. Immunol. 162, 2375-2383 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 2375-2383
-
-
Randolph, D.A.1
Carruthers, C.J.2
Szabo, S.J.3
Murphy, K.M.4
Chaplin, D.D.5
-
13
-
-
0034890907
-
Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen
-
Akbari, O., DeKruyff, R.H. & Umetsu, D.T. Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2, 725-731 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 725-731
-
-
Akbari, O.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
14
-
-
0033136302
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
-
+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J. Immunol. 162, 5317-5326 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 5317-5326
-
-
Itoh, M.1
-
15
-
-
0037455003
-
+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10
-
+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10. J. Exp. Med. 197 181-193 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 181-193
-
-
Lohning, M.1
-
16
-
-
0033696961
-
The CD28-related molecule ICOS is required for effective T cell-dependent immune responses
-
Coyle, A.J. et al. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity 13, 95-105 (2000).
-
(2000)
Immunity
, vol.13
, pp. 95-105
-
-
Coyle, A.J.1
-
17
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong, C. et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 409, 97-101 (2001).
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
-
18
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam, A.J. et al. ICOS is critical for CD40-mediated antibody class switching. Nature 409, 102-105 (2001).
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
-
19
-
-
0035804269
-
ICOS is essential for effective T-helper-cell responses
-
Tafuri, A. et al. ICOS is essential for effective T-helper-cell responses. Nature 409, 105-109 (2001).
-
(2001)
Nature
, vol.409
, pp. 105-109
-
-
Tafuri, A.1
-
20
-
-
0034327808
-
+ T cells
-
+ T cells. J. Immunol. 165, 5035-5040 (2000).
-
(2000)
J. Immunol.
, vol.165
, pp. 5035-5040
-
-
McAdam, A.J.1
-
21
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 1057-1061 (2003).
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
22
-
-
0032532606
-
Heat killed Listeria monocytogenes as an adjuvant converts established Th2-dominated immune responses into Th1-dominated responses
-
Yeung, V.P., Gieni, R.S., Umetsu, D.T. & DeKruyff, R.H. Heat killed Listeria monocytogenes as an adjuvant converts established Th2-dominated immune responses into Th1-dominated responses. J. Immunol. 161, 4146-4152 (1998).
-
(1998)
J. Immunol.
, vol.161
, pp. 4146-4152
-
-
Yeung, V.P.1
Gieni, R.S.2
Umetsu, D.T.3
DeKruyff, R.H.4
-
23
-
-
0033664788
-
Allergen immunotherapy: Novel approaches in the management of allergic diseases and asthma
-
Campbell, D., DeKruyff, R.H. & Umetsu, D.T. Allergen immunotherapy: novel approaches in the management of allergic diseases and asthma. Clin. Immunol. 97, 193-202 (2000).
-
(2000)
Clin. Immunol.
, vol.97
, pp. 193-202
-
-
Campbell, D.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
24
-
-
3442889104
-
+ T cells regulate immune responses in a murine model of allergen-induced sensitization and airway inflammation
-
+ T cells regulate immune responses in a murine model of allergen-induced sensitization and airway inflammation. Eur. J. Immunol. 34, 1817-1827 (2004).
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 1817-1827
-
-
Stock, P.1
-
26
-
-
0036736840
-
CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hypperreactivity and inflammation
-
Oh, J.W. et al. CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hypperreactivity and inflammation. J. Allergy Clin. Immunol. 110, 460-468 (2002 ).
-
(2002)
J. Allergy Clin. Immunol.
, vol.110
, pp. 460-468
-
-
Oh, J.W.1
-
27
-
-
0002691620
-
+ Th cells engineered To produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation
-
+ Th cells engineered To produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J. Clin. Invest. 11, 89-96 (2000).
-
(2000)
J. Clin. Invest.
, vol.11
, pp. 89-96
-
-
Hansen, G.1
-
28
-
-
0029984051
-
Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-γ and interleukin-10
-
Gerosa, F. et al. Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-γ and interleukin-10. J. Exp. Med. 183, 2559-2569 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2559-2569
-
-
Gerosa, F.1
-
29
-
-
0035914926
-
Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection
-
Trinchieri, G. Regulatory role of T cells producing both interferon γ and interleukin 10 in persistent infection. J. Exp. Med. 194, F53-57 (2001).
-
(2001)
J. Exp. Med.
, vol.194
-
-
Trinchieri, G.1
-
30
-
-
0035914841
-
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
-
Belkaid, Y. et al. The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194, 1497-1506 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 1497-1506
-
-
Belkaid, Y.1
-
31
-
-
0032520148
-
Identification of a T cell subset capable of both IFN-γ and IL-10 secretion in patients with chronic Borrelia burgdorferi infection
-
Pohl-Koppe, A., Balashov, K.E., Steere, A.C., Logigian, E.L. & Hafler, D.A. Identification of a T cell subset capable of both IFN-γ and IL-10 secretion in patients with chronic Borrelia burgdorferi infection. J. Immunol. 160, 1804-1810 (1998).
-
(1998)
J. Immunol.
, vol.160
, pp. 1804-1810
-
-
Pohl-Koppe, A.1
Balashov, K.E.2
Steere, A.C.3
Logigian, E.L.4
Hafler, D.A.5
-
32
-
-
0029984051
-
Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-γ and interleukin-10
-
Gerosa, F. et al. Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-γ and interleukin-10. J. Exp. Med. 183, 2559-2569 (1996).
-
(1996)
J. Exp. Med.
, vol.183
, pp. 2559-2569
-
-
Gerosa, F.1
-
33
-
-
0034613767
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192, 1213-1222 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1213-1222
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
34
-
-
0035903326
-
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
-
Hawiger, D. et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194, 769-779 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 769-779
-
-
Hawiger, D.1
-
35
-
-
0037039379
-
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
-
Steinman, R.M. & Nussenzweig, M.C. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 99, 351-358 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 351-358
-
-
Steinman, R.M.1
Nussenzweig, M.C.2
-
36
-
-
0037122011
-
+ T cell tolerance
-
+ T cell tolerance. J. Exp. Med. 196 1627-1638 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1627-1638
-
-
Bonifaz, L.1
-
37
-
-
0031798137
-
Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells
-
Inaba, K. et al. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J. Exp. Med. 188, 2163-2173 (1998).
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2163-2173
-
-
Inaba, K.1
-
38
-
-
0037152141
-
+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens
-
+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J. Exp. Med. 196, 1099-1104 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1099-1104
-
-
Belz, G.T.1
-
39
-
-
0037141105
-
+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo
-
+ dendritic cell subset selectively endocytoses dying cells in culture and in vivo. J. Exp. Med. 195, 1289-1302 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1289-1302
-
-
Iyoda, T.1
-
40
-
-
0037152164
-
Immune tolerance after delivery of dying cells to dendritic cells in situ
-
Liu, K. et al. Immune tolerance after delivery of dying cells to dendritic cells in situ. J. Exp. Med. 196, 1091-1097 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1091-1097
-
-
Liu, K.1
-
41
-
-
0035202483
-
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
-
Asselin-Paturel, C. et al. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2, 1144-1150 (2001).
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1144-1150
-
-
Asselin-Paturel, C.1
-
42
-
-
0037987977
-
Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo
-
Wakkach, A. et al. Characterization of dendritic cells that induce tolerance and T regulatory 1 cell differentiation in vivo. Immunity 18, 605-617 (2003).
-
(2003)
Immunity
, vol.18
, pp. 605-617
-
-
Wakkach, A.1
-
43
-
-
0037388926
-
Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells
-
Krug, A. et al. Interferon-producing cells fail to induce proliferation of naive T cells but can promote expansion and T helper 1 differentiation of antigen-experienced unpolarized T cells. J. Exp. Med. 197, 899-906 (2003).
-
(2003)
J. Exp. Med.
, vol.197
, pp. 899-906
-
-
Krug, A.1
-
44
-
-
0037100317
-
+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential
-
+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential. Blood 100, 383-390 (2002).
-
(2002)
Blood
, vol.100
, pp. 383-390
-
-
Martin, P.1
-
45
-
-
0037148511
-
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: A novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis
-
McGuirk, P., McCann, C. & Mills, K.H. Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis. J. Exp. Med. 195, 221-231 (2002).
-
(2002)
J. Exp. Med.
, vol.195
, pp. 221-231
-
-
McGuirk, P.1
McCann, C.2
Mills, K.H.3
-
46
-
-
0033514364
-
Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
-
Pulendran, B. et al. Distinct dendritic cell subsets differentially regulate the class of immune response in vivo. Proc. Natl. Acad. Sci. USA 96, 1036-1041 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1036-1041
-
-
Pulendran, B.1
-
47
-
-
0033068180
-
- subclasses of dendritic cells direct the development of distinct T helper cells in vivo
-
- subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J. Exp. Med. 189, 587-592 (1999).
-
(1999)
J. Exp. Med.
, vol.189
, pp. 587-592
-
-
Maldonado-Lopez, R.1
-
48
-
-
2442450433
-
+ regulatory T cells
-
+ regulatory T cells. J. Immunol. 172, 5986-5993 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 5986-5993
-
-
Vieira, P.L.1
-
49
-
-
2542420993
-
In vivo instruction of suppressor commitment in naive T cells
-
Apostolou, I. & Von Boehmer, H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199, 1401-1408 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1401-1408
-
-
Apostolou, I.1
Von Boehmer, H.2
-
50
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett, C.L. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat. Genet. 27, 20-21 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
51
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R.S. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat. Genet. 27, 18-20 (2001).
-
(2001)
Nat. Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
52
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T.A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-81 (2000).
-
(2000)
J. Clin. Invest.
, vol.106
-
-
Chatila, T.A.1
-
54
-
-
0028262128
-
Determination of lymphocyte division by flow cytometry
-
Lyons, A.B. & Parish, C.R. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171, 131-137 (1994).
-
(1994)
J. Immunol. Methods
, vol.171
, pp. 131-137
-
-
Lyons, A.B.1
Parish, C.R.2
-
55
-
-
0028267766
-
Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin-10 in interferon-γ and in interleukin-4-expressing cells
-
Assenmacher, M., Schmitz, J. & Radbruch, A. Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-γ and in interleukin-4-expressing cells. Eur. J. Immunol. 24, 1097-2010 (1994).
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1097-2010
-
-
Assenmacher, M.1
Schmitz, J.2
Radbruch, A.3
-
57
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo, S.J. et al. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 100, 655-669 (2000).
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
-
58
-
-
0030800586
-
Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
-
Hamelmann, E. et al. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am. J. Respir. Crit. Care Med. 156, 766-775 (1997).
-
(1997)
Am. J. Respir. Crit. Care Med.
, vol.156
, pp. 766-775
-
-
Hamelmann, E.1
-
59
-
-
0023896897
-
Pulmonary responses to bronchoconstrictor agonists in the mouse
-
Martin, T.R., Gerard, N.P., Galli, S.J. & Drazen, J.M. Pulmonary responses to bronchoconstrictor agonists in the mouse. J. Appl. Physiol. 64, 2318-2323 (1988).
-
(1988)
J. Appl. Physiol.
, vol.64
, pp. 2318-2323
-
-
Martin, T.R.1
Gerard, N.P.2
Galli, S.J.3
Drazen, J.M.4
|