Elevated Levels of CD4+CD25+FoxP3+ T Cells in Systemic Sclerosis Patients Contribute to the Secretion of IL-17 and Immunosuppression Dysfunction

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Liu, Xinjuan ^a   Gao, Na ^a   Li, Mengtao ^a   Xu, Dong ^a   Hou, Yong ^a   Wang, Qian ^a   Zhang, Guohua ^a   Sun, Qiuning ^a   Zhang, Henghui ^b   Zeng, Xiaofeng ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45RA ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3;

ADULT; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; FLOW CYTOMETRY; FOXP3+ T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; LYMPHOCYTE ACTIVATION; MALE; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; SYSTEMIC SCLEROSIS; T LYMPHOCYTE; TH17 CELL;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; FEMALE; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNE TOLERANCE; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; SCLERODERMA, SYSTEMIC; T-LYMPHOCYTES, REGULATORY;

EID: 84878922773     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0064531     Document Type: Article

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