TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2278-2290

  Nyirenda, Mukanthu H ^a   Sanvito, Lara ^a   Darlington, Peter J ^b   O'Brien, Kate ^a   Zhang, Guang Xian ^c   Constantinescu, Cris S ^a   Bar Or, Amit ^b   Gran, Bruno ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b MCGILL UNIVERSITY   (Canada)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45RA ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 22; INTERLEUKIN 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; AUTOIMMUNITY; CELL DIFFERENTIATION; CELL EXPANSION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; LIGAND BINDING; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PATHOGEN CLEARANCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TH17 CELL;

CELL DIFFERENTIATION; CELL SEPARATION; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE ACTIVATION; PHENOTYPE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TOLL-LIKE RECEPTOR 2;

EID: 80052677833     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003715     Document Type: Article

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