Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways

Pharmacology and Therapeutics

Volumn 140, Issue 3, 2013, Pages 280-289

  Bozinovski, Steven ^a   Anthony, Desiree ^a   Anderson, Gary P ^a   Irving, Louis B ^b   Levy, Bruce D ^c   Vlahos, Ross ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Airway inflammation; COPD; Neutrophils; Resolution

Indexed keywords

ALX FPR2 RECEPTOR; AZITHROMYCIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CHEMOATTRACTANT; DEXAMETHASONE; G PROTEIN COUPLED RECEPTOR; HISTONE DEACETYLASE 2; I KAPPA B KINASE INHIBITOR; LEUKOCYTE ELASTASE; PHOSPHODIESTERASE IV INHIBITOR; SERUM AMYLOID A; THEOPHYLLINE; UNCLASSIFIED DRUG;

ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; CELL ACTIVATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL (TOPIC); CORTICOSTEROID THERAPY; CYTOKINE PRODUCTION; DEGRANULATION; EXOCYTOSIS; HUMAN; LEUKOCYTE ACTIVATION; LOW DRUG DOSE; NEUTROPHILIA; NEUTROPHILIC DEGRANULATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN TARGETING;

AIRWAY INFLAMMATION; COPD; NEUTROPHILS; RESOLUTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; HUMANS; NEUTROPHILS; PNEUMONIA; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LIPOXIN; SIGNAL TRANSDUCTION;

EID: 84885478791     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.07.007     Document Type: Review

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