Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 288, Issue 3 32-3, 2005, Pages

  Stevenson, Christopher S ^a,b   Coote, Kevin ^a   Webster, Ruth ^a   Johnston, Helinor ^a   Atherton, Hazel C ^a   Nicholls, Andrew ^a   Giddings, June ^a   Sugar, Rosemary ^a   Jackson, Alan ^a   Press, Neil J ^a   Brown, Zarin ^a   Butler, Keith ^a   Danahay, Henry ^a  

^a Novartis Institute of Biomedical Research   (United Kingdom)

^b Novartis Institutes for Biomedical Research   (United Kingdom)

Author keywords

Chronic obstructive pulmonary disease; Cytokine induced neutrophil chemoattractant; Neutrophils; Smoking

Indexed keywords

CHEMOKINE RECEPTOR ANTAGONIST; CHEMOKINE RECEPTOR CXCR2; CIGARETTE SMOKE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; INTERLEUKIN 1BETA; SB 332235; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE COURSE; GENE EXPRESSION; INFLAMMATION; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MUCUS SECRETION; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SMOKING;

ANIMALS; LIGANDS; LUNG; MALE; MUCUS; PNEUMONIA; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-8B; SMOKE; TOBACCO;

EID: 13644267621     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00317.2004     Document Type: Article

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