Activation of lipoxin A4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation

Journal of Experimental Medicine

Volumn 191, Issue 7, 2000, Pages 1197-1207

  Chiang, Nan ^a   Fierro, Iolanda M ^a   Gronert, Karsten ^a   Serhan, Charles N ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Antiinflammation; Inhibitory receptors; Leukocytes; MHC binding peptide; Resolution

Indexed keywords

ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; CELL SURFACE RECEPTOR; CHEMOTACTIC PEPTIDE; CHIMERIC PROTEIN; FORMYLPEPTIDE RECEPTOR LIKE 1; LEUKOTRIENE B4 RECEPTOR; LIPOXIN; LIPOXIN A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; INFLAMMATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CALCIUM; CELL LINE; CHO CELLS; CRICETINAE; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; LIGANDS; LIPOXINS; MACROPHAGE INFLAMMATORY PROTEIN-1; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR STRUCTURE; MONOKINES; NEUTROPHILS; OLIGOPEPTIDES; PEPTIDES; RECEPTORS, CELL SURFACE; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LEUKOTRIENE B4; RECEPTORS, LIPOXIN; SERUM AMYLOID A PROTEIN; SIGNAL TRANSDUCTION;

EID: 0034599741     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.7.1197     Document Type: Article

References (48)

1. Cotran, R.S. 1999. Inflammation: historical perspectives. In Inflammation: Basic Principles and Clinical Correlates, 3rd ed. J.I. Gallin, K. Snyderman, D.T. Fearon, B.F. Haynes, and C. Nathan, editors. Lippincott Williams & Wilkins, Philadelphia. 5-10.
2. Weissmann, G., J.E. Smolen, and H.M. Korchak. 1980. Release of inflammatory mediators from stimulated nentrophils. N. Engl. J. Med. 303:27-34.
3. Samuelsson, B. 1982. From studies of biochemical mechanisms to novel biological mediators: prostaglandin endoperoxides, thromboxanes and leukotrienes. In Les Prix Nobel: Nobel Prizes. Presentations, Biographies and Lectures. T. Frängsmyr, editor. Almqvist & Wiksell, Stockholm. 153-174.
4. 4 that mediates chemotaxis. Nature. 387:620-624.
5. Perez, H.D. 1994. Chemoattractant receptors. Curr. Opin. Hematol. 1:40-44.
6. Pillinger, M.H., and S.B. Abramson. 1995. The neutrophil in rheumatoid arthritis. Rheum. Dis. Clin. North Am. 21:691-714.
7. Serhan, C.N., J.Z. Haeggstrom, and C.C. Leslie. 1996. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J. 10:1147-1158.
8. Diamond, P., A. McGinty, D. Sugrue, H.R. Brady, and C. Godson. 1999. Regulation of leukocyte trafficking by lipoxins. Clin. Chem. Lab. Med. 37:293-297.
9. Node, K., Y. Huo, X. Ruan, B. Yang, M. Spiecker, K. Ley, D.C. Zeldin, and J.K. Liao. 1999. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science. 285:1276-1279.
10. Munger, K.A., A. Montero, M. Fukunaga, S. Uda, T. Yura, K. Imai, Y. Kaneda, J.M. Valdivielso, and K.F. Badr. 1999. Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. Proc. Natl. Acad. Sci. USA. 96:13375-13380.
11. Weissmann, G. 1991. Aspirin. Sci. Am. 264:84-90.
12. Marcus, A.J. 1995. Aspirin as prophylaxis against colorectal cancer. N. Eng. J. Med. 333:656-658.
13. 4 stable analogs are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J. Exp. Med. 185:1693-1704.
14. Clish, C.B., J.A. O'Brien, K. Gronert, G.L. Stahl, N.A. Petasis, and C.N. Serhan. 1999. Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc. Natl. Acad. Sci. USA. 96:8247-8252.
15. 4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. J. Clin. Invest. 104: 309-316.
16. 4 inhibit tumor necrosis factor α-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis. J. Exp. Med. 189:1923-1929.
17. 4 receptor. J. Exp. Med. 180:253-260.
18. 4 receptor interaction. Biochemistry. 34:16678-16686.
19. Quehenberger, O., E.R. Prossnitz, S.L. Cavanagh, C.G. Cochrane, and R.D. Ye. 1993. Multiple domains of the N-formyl peptide receptor are required for high-affinity ligand binding. Construction and analysis of chimeric N-formyl peptide receptors. J. Biol. Chem. 268:18167-18175.
20. Castano, A.R., S. Tangri, J.E. Miller, H.R. Holcombe, M.R. Jackson, W.D. Huse, M. Kronenberg, and P.A. Peterson. 1995. Peptide binding and presentation by mouse CD1. Science. 269:223-226.
21. Beckman, E.M., S.A. Porcelli, C.T. Morita, S.M. Behar, S.T. Furlong, and M.B. Brenner. 1994. Recognition of a lipid antigen by CD1-restricted αβ+ T cells. Nature. 372: 691-694.
22. 4 by stimulated human whole blood. Biol. Mass Spectrom. 20:45-52.
23. Falk, W., R.H. Goodwin, and E. Leonard. 1980. A 48-well microchemotaxis assembly for rapid and accurate measurement of leukocyte migration. J. Immunol. Methods. 33:239-247.
24. Gronert, K., S.P. Colgan, and C.N. Serhan. 1998. Characterization of human neutrophil and endothelial cell ligand-operated extracellular acidification rate by microphysiometry: impact of reoxygenation. J. Pharmacol. Exp. Ther. 285:252-261.
25. Wang, C.R., A.R. Castano, P.A. Peterson, C. Slaughter, K.F. Lindahl, and J. Deisenhofer. 1995. Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3. Cell. 82:655-664.
26. Shawar, S.M., R.R. Rich, and F.F. Becker. 1995. Peptides from the amino-terminus of mouse mitochondrially encoded NADH dehydrogenase subunit 1 are potent chemoattractants. Biochem. Biophys. Res. Commun. 211:812-818.
27. 4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry. 34:14609-14615.
28. Klein, C., J.I. Paul, K. Sauve, M.M. Schmidt, L. Arcangeli, J. Ransom, J. Trueheart, J.P. Manfredi, J.R. Broach, and A.J. Murphy. 1998. Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast. Nat. Biotechnol. 16:1334-1337.
29. Tessier, P.A., P.H. Naccache, I. Clark-Lewis, R.P. Gladue, K.S. Neote, and S.R. McColl. 1997. Chemokine networks in vivo: involvement of C-X-C and C-C chemokines in neutrophil extravasation in vivo in response to TNF-α. J. Immunology. 159:3595-3602.
30. Gabay, C., and I. Kushner. 1999. Acute-phase proteins and other systemic responses to inflammation. N. Engl. J. Med. 340:448-454.
31. Su, S.B., W. Gong, J.F. Gao, W. Shen, P.M. Murphy, J.J. Oppenheim, and J.M. Wang. 1999. A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J. Exp. Med. 189:395-402.
32. Miettinen, H.M., J.M. Gripentrog, and A.J. Jesaitis. 1998. Chemotaxis of chinese hamster ovary cells expressing the human neutrophil formyl peptide receptor: role of signal transduction molecules and α5β1 integrin. J. Cell Sci. 111:1921-1928.
33. 4 receptor. J. Biol. Chem. 272:6972-6978.
34. Villanueva, M.S., C.J. Becker, and E.G. Pamer. 1994. Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. J. Exp. Med. 180:2137-2145.
35. Olofsson, S., B. Khanna, and E. Lycke. 1980. Altered kinetic properties of sialyl and galactosyl transferases associated with herpes simplex virus infection ot GMK and BHK cells. J. Gen. Virol. 47:1-9.
36. Kim, J.W., and J.M. Cunningham. 1993. N-linked glycosylation of the receptor for murine ecotropic retroviruses is altered in virus-infected cells. J. Biol. Chem. 268:16316-16320.
37. Miettinen, H.M., J.S. Mills, J.M. Gripentrog, E.A. Dratz, B.L. Granger, and A.J. Jesaitis. 1997. The ligand binding site ot the formyl peptide receptor maps in the transmembrane region. J. Immunol. 159:4045-4054.
38. Quehenberger, O., Z.K. Pan, H.R. Prossnitz, S.L. Cavanagh, C.G. Cochrane, and R.D. Ye. 1997. Identification of an N-formyl peptide receptor ligand binding domain by a gain-of-function approach. Biochem. Biophys. Res. Commun. 238: 377-381.
39. Tai, H.H., C. Huang, and N. Chiang. 1997. Structure and function of prostanoid receptors as revealed by site-directed mutagenesis. In Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury. K.V. Honn, L.J. Marnett, R. Jones, and P.Y.-K. Wong, editors. Plenum Press, New York. 205-209.
40. 4 with human neutrophils. J. Biol. Chem. 267:16168-16176.
41. Liang, J.S., and J.D. Sipe. 1995. Recombinant human serum amyloid A (apoSAAp) binds cholesterol and modulates cholesterol flux. J. Lipid Res. 36:37-46.
42. Linke, R.P., V. Bock, G. Valet, and G. Rothe. 1991. Inhibition of the oxidative burst response of N-formyl peptide-stimulated neutrophils by serum amyloid-A protein. Biochem. Biophys. Res. Commun. 176:1100-1105.
43. 4R. Blood. 94:1165-1173.
44. Pettit, E.J., and F.S. Fay. 1998. Cytosolic tree calcium and the cytoskeleton in the control of leukocyte chemotaxis. Physiol. Rev. 28:949-960.
45. Serhan, C.N. 1994. Lipoxin biosynthesis and its impact in inflammatory and vascular events. Biochem. Biophys. Acta. 1212: 1-25.
46. 4. FASEB J. 13:903-911.
47. 4: a new class of ligand for the Ah receptor. Biochemistry. 38: 7594-7600.
48. Fernandez-Salguero, P., T. Pineau, D.M. Hilbert, T. McPhail, S.S.T. Lee, S. Kimura, D.W. Neben, S. Rudikoff, J.M. Ward, and F.J. Gonzalez. 1995. Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor. Science. 268:722-726.