CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 2, 1999, Pages 711-717

  Saetta, Marina ^a,b   Baraldo, Simonetta ^a,b   Corbino, Laura ^a,b   Turato, Graziella ^a,b   Braccioni, Fausto ^a,b   Rea, Federico ^a,b   Cavallesco, Giorgio ^a,b   Tropeano, Giuseppe ^a,b   Mapp, Cristina E ^a,b   Maestrelli, Piero ^a,b   Ciaccia, Adalberto ^a,b   Fabbri, Leonardo M ^a,b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PULMONARY ARTERY; RESPIRATORY AIRFLOW; SMOKING; T LYMPHOCYTE SUBPOPULATION;

EID: 0032798485     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.2.9812020     Document Type: Article

References (29)

1. 1. Am. J. Respir. Crit. Care Med. 155:852-857.
2. 2. Saetta, M., A. Di Stefano, G. Turato, F. M. Faechini, L. Corbino, C. E. Mapp, P. Maestrelli, A. Ciaccia, and L. M. Fabbri. 1998. CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 157:822-826.
3. 3. Eidelman, D., M. Saetta, H. Ghezzo, N. S. Wang, J. R. Hoidal, M. King, and M. G. Cosio. 1990. Cellularity of the alveolar walls in smokers and its relation to alveolar destruction. Am. Rev. Respir. Dis. 141:1547-1552.
4. 4. Finkelstein, R., R. S. Fraser, H. Ghezzo, and M. G. Cosio. 1995. Alveolar inflammation and its relation to emphysema in smokers. Am. J. Respir. Crit. Care Med. 152:1666-1672.
5. 5. Martin, T. R., G. Raghu, R. J. Maunder, and S. C. Springmeyer. 1985. The effect of chronic bronchitis and chronic air-flow obstruction on lung cell populations recovered by bronchoalveolar lavage. Am. Rev. Respir. Dis. 132:254-260.
6. 6. Thompson, A. B., D. Daughton, R. A. Robbins, M. A. Ghafouri, M. Oehlerking, and S. I. Rennard. 1989. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am. Rev. Respir. Dis. 140:1527-1537.
7. 7. Linden, M., J. B. Rasmussen, E. Piitulainen, A. Tunek, M. Larson, H. Tegner, P. Venge, L. A. Laitinen, and R. Brattsand. 1993. Airway inflammation in smokers with nonobstructive and obstructive chronic bronchitis. Am. Rev. Respir. Dis. 148:1226-1232.
8. 8. Cosio, M., H. Ghezzo, J. C. Hogg, R. Corbin, M. Loveland, J. Dosman, and P. T. Macklem. 1977. The relations between structural changes in small airways and pulmonary-function tests. N. Engl. J. Med. 298:1277-1281.
9. 9. Cosio, M. G., K. A. Hale, and D. E. Niewoehner. 1980. Morphologic and morphometric effects of prolonged cigarette smoking on the small airways. Am. Rev. Respir. Dis. 122:266-271.
10. 10. Niewoehner, D. F., J. Kleinerman, and D. B. Rice. 1974. Pathologic changes in the peripheral airways of young cigarette smokers. N. Engl. J. Med. 291:755-758.
11. 11. Berend, N., J. L. Wright, W. M. Thurlbeck, G. E. Marlin, and A. J. Woolcock. 1981. Small airway disease: reproducibility of measurements and correlation with lung function. Chest 79:263-268.
12. 12. Wright, J. L., L. M. Lawson, P. D. Pare, S. Kennedy, B. Wiggs, and J. C. Hogg. 1984. The detection of small airways disease. Am. Rev. Respir. Dis. 129:989-994.
13. 13. Hale, K. A., S. L. Ewing, B. A. Gosnell, and D. E. Niewoehner. 1984. Lung disease in long term cigarette smokers with and without chronic airflow obstruction. Am. Rev. Respir. Dis. 130:718-721.
14. 14. Saetta, M., R. Finkelstein, and M. G. Cosio. 1994. Morphological and cellular basis for airflow limitation in smokers. Eur. Respir. J. 7:1505-1515.
15. 15. Bosken, C. H., J. Hards, K. Gatter, and J. C. Hogg. 1992. Characterization of the inflammatory reaction in the peripheral airways of cigarette smokers using immunohistochemistry. Am. Rev. Respir. Dis. 145: 911-917.
16. 16. Hale, K. A., D. E. Niewoehner, and M. G. Cosio. 1980. Morphological changes in the muscular pulmonary arteries: relationship to cigarette smoking, airway disease and emphysema. Am. Rev. Respir. Dis. 122: 273-278.
17. 17. Peinado, V. I., J. A. Barberà, J. Ramirez, J. P. Gomez, J. Roca, L. Jover, J. M. Gimferrer, and R. Rodriguez-Roisin. 1998. Endothelial dysfunction in pulmonary arteries of patients with mild COPD. Am. J. Physiol. L908-L913.
18. 18. Barbera, J. A., A. Riverola, J. Roca, J. Ramirez, P. D. Wagner, D. Ros, B. R. Wiggs, and R. Rodriguez-Roisin. 1994. Pulmonary vascular abnormalities and ventilation-perfusion relationships in mild chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 149:423-429.
19. 19. Dunnill, M. S. 1961. An assessment of the anatomical factor in cor pulmonale in emphysema. J. Clin. Pathol. 14:246-258.
20. 20. Wright, J. L., T. Petty, and W. M. Thurlbeck. 1992. Analysis of the structure of the muscular pulmonary arteries in patients with pulmonary hypertension and COPD: National Institutes of Health Nocturnal Oxygen Therapy Trial. Lung 170:109-124.
21. 21. 1995. Optimal assessment and management of chronic obstructive pulmonary disease (COPD). Eur. Respir. J. 8:1398-1420.
22. 22. Saetta, M., A. Di Stefano, P. Maestrelli, G. Turato, M. P. Ruggieri, A. Roggeri, P. Calcagni, C. E. Mapp, A. Ciaccia, and L. M. Fabbri. 1994. Airway eosinophilia in chronic bronchitis during exacerbations. Am. J. Respir. Crit. Care Med. 150:1646-1652.
23. 23. Communité Europeenne du Carbon e de l'Acier. 1971. Aide-memoire of Spirographic Practice for Examining Ventilatory Function, 2nd ed. Industrial Health and Medicine, Luxemburg.
24. 24. Saetta, M., A. Di Stefano, C. Rosina, G. Thiene, and L. M. Fabbri. 1991. Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am. Rev. Respir. Dis. 143:138-143.
25. 25. Saetta, M., G. Turato, F. M. Faechini, L. Corbino, R. E. Lucehini, G. Casoni, P. Maestrelli, C. E. Mapp, A. Ciaccia, and L. M. Fabbri. 1997. Inflammatory cells in the bronchial glands of smokers with chronic bronchitis. Am. J. Respir. Crit. Care Med. 156:1633-1639.
26. 26. Andoh, Y., S. Shimura, T. Aikawa, H. Sasaki, and T. Takishima. 1992. Perivascular fibrosis of muscular pulmonary arteries in chronic obstructive pulmonary disease. Chest 102:1645-1650.
27. 27. Ramsay, A., J. Ruby, and I. Ramshaw. 1993. A case for cytokines as effector molecules in the resolution of virus infection. Immunol. Today 14:155-157.
28. 28. Isaacs, D., C. R. M. Bangham, and A. J. McMichael. 1987. Cell-mediated cytotoxic response to respiratory syncytial virus in infants with bronchiolitis. Lancet 769-771.
29. 29. Hogg, J. 1997. Latent adenoviral infections in the pathogenesis of COPD. Eur. Respir. Rev. 7:216-220.