A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells

Journal of Experimental Medicine

Volumn 189, Issue 2, 1999, Pages 395-402

  Su, Shao Bo ^d   Gong, Wanghua ^a   Gao, Ji Liang ^b   Shen, Weiping ^d   Murphy, Philip M ^b   Oppenheim, Joost J ^d   Wang, Ji Ming ^c  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NONE

Author keywords

Calcium flux; Chemotaxis; FPRL1; Receptor; Serum amyloid A

Indexed keywords

AMYLOID A PROTEIN; CHEMOATTRACTANT; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE RECEPTOR;

ARTICLE; CALCIUM MOBILIZATION; CELL MIGRATION; CHEMOTAXIS; DESENSITIZATION; HUMAN; HUMAN CELL; PHAGOCYTE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; APOLIPOPROTEINS; CALCIUM; CELL LINE; CHEMOTACTIC FACTORS; CHEMOTAXIS; GTP-BINDING PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; MONOCYTES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; PHAGOCYTES; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOXIN; RECEPTORS, PEPTIDE; SERUM AMYLOID A PROTEIN; TRANSFECTION;

EID: 0000485181     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.2.395     Document Type: Article

References (43)

1. Sipe, J.D. 1990. The acute-phase response. In Immunophysiology: The Role of Cells and Cytokines in Immunity and Inflammation. J.J. Oppenheim and E.M. Shevach, editors. Oxford University Press, New York. 259-273.
2. Kisilevsky, R. 1991. Serum amyloid A (SAA), a protein without a function: some suggestions with reference to cholesterol metabolism. Med. Hypotheses. 35:337-341.
3. Skinner, M. 1992. Protein AA/SAA. J. Intern. Med. 232: 513-514.
4. Malle, E., and F.C. De Beer. 1996. Human serum amyloid A (SAA) protein: a prominent acute-phase reactant for clinical practice. Eur. J. Clin. Invest. 26:427-435.
5. Badolato, R., J.M. Wang, W.J. Murphy, A.R. Lloyd, D.F. Michiel, L.L. Bausserman, D.J. Kelvin, and J.J. Oppenheim. 1994. Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes. J. Exp. Med. 180:203-209.
6. Xu, L., R. Badolato, W.J. Murphy, D.L. Longo, M. Anver, S. Hale, J.J. Oppenheim, and J.M. Wang. 1995. A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion. J. Immunol. 155:1184-1190.
7. Badolato, R., J.A. Johnston, J.M. Wang, D. McVicar, L.L. Xu, J.J. Oppenheim, and D.J. Kelvin. 1995. Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway. J. Immunol. 155:4004-4010.
8. Prossnitz, E.R., and R.D. Ye. 1997. The N-formyl peptide receptor: a model for the study of chemoattractant receptor structure and function. Pharmacol. Ther. 74:73-102.
9. Murphy, P.M. 1996. The N-formyl peptide chemotactic receptors. In Chemoattractant Ligands and Their Receptors. CRC Press, Boca Raton, FL. 269 pp.
10. Murphy, P.M., T. Ozcelik, R.T. Kenney, H.L. Tiffany, D. McDermott, and U. Francke. 1992. A structural homologue of the N-formyl peptide receptor. Characterization and chromosome mapping of a peptide chemoattractant receptor family J. biol. Chem. 267:7637-7643.
11. Ye, R.D., S.L. Cavanagh, O. Quehenberger, E.R. Prossnitz, and C.G. Cochrane. 1992. Isolation of a cDNA that encodes a novel granulocyte N-formyl peptide receptor. Biochem. Biophys. Res. Commun. 184:582-589.
12. Bao, L., N.P. Gerard, R.L. Eddy, Jr., T.B. Shows, and C. Gerard. 1992. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. Genomics. 13:437-440.
13. Gao, J.L., and P.M. Murphy. 1993. Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains. J. Biol. Chem. 268: 25395-25401.
14. Nomura, H., B.W. Nielsen, and K. Matsushima.1993. Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors. Int. Immunol. 5:1239-1249.
15. Fiore S., J.F. Maddox, H.D. Ferez, and C.N. Serhan. 1994. Identification of a human cDNA encoding a functional high affinity lipoxin A4 receptor. J. Exp. Med. 180:253-260.
16. Takano, T., S. Fiore, J.F. Maddox, H.R. Brady, N.A. Petasis, and C.N. Serhan. 1997. Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors. J. Exp. Med. 185:1693-1704.
17. Maddox, J.F., M. Hachicha, T. Takano, N.A. Petasis, V.V. Fokin, and C.N. Serhan. 1997. Lipoxin A4 stable analogs are potent mimetics that stimulate human monocytes and THP-1 cells via a G-protein-linked lipoxin A4 receptor. J. Biol. Chem. 272:6972-6978.
18. Fiore, S., M. Romano, E.M. Reardon, and C.N. Serhan. 1993. Induction of functional lipoxin A4 receptors in HL-60 cells. Blood. 81:3395-3403.
19. Fiore, S., and C.N. Serhan. 1995. Lipoxin A4 receptor activation is distinct from that of the formyl peptide receptor in myeloid cells: inhibition of CD11/18 expression by lipoxin A4-lipoxin A4 receptor interaction. Biochemistry. 34:16678-16686.
20. Gronert, K., A. Gewirtz, J.L. Madara, and C.N. Serhan. 1998. Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon γ and inhibits tumor necrosis factor α-induced IL-8 release. J. Exp. Med. 187:1285-1294.
21. Gewirtz, A.T., B. McCormick, A.S. Neish, N.A. Petasis, K. Gronert, C.N. Serhan, and J.L. Madara. 1998. Pathogeninduced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. J. Clin. Invest. 101: 1860-1869.
22. 2+ mobilization. J. Immunol. 157:2149-2154.
23. Colgan, S.P., C.N. Serhan, C.A. Parkos, C. Delp-Archer, and J.L. Madara 1993. Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. J. Clin. Invest. 92:75-82.
24. Takano, T., C.B. Clish, K. Gronert, N. Petasis, and C.N. Serhan. 1998. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. J. Clin. Invest. 101:819-826.
25. Yokomizo, T., T. Izumi, K. Chang, Y. Takuwa, and T. Shimizu. 1997. A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis. Nature. 387:620-624.
26. Owman, C., A. Garzino-Demo, F. Cocchi, M. Popovic, A. Sabirsh, and R.C. Gallo. 1998. The leukotriene B4 receptor functions as a novel type of coreceptor mediating entry of primary HIV-1 isolates into CD4-positive cells. Proc. Natl. Acad. Sci. USA. 95:9530-9534.
27. Berger, E.A. HIV entry and tropism: the chemokine receptor connection. 1997. AIDS. 11:S3-S16.
28. Steinkasserer, A., E.H. Weiss, W. Schwaeble, and R.P. Linke. 1990. Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis. Biochem. J. 268:187-193.
29. Murphy, P.M., and D. McDermott. 1991. Functional expression of the human formyl peptide receptor in Xenopus oocytes requires a complementary human factor. J. Biol. Chem. 266: 12560-12567.
30. Ali, H., S. Sozzani, I. Fisher, A.J. Barr, R.M. Richardson, B. Haribabu, and R. Snyderman. 1998. Differential regulation of formyl peptide and platelet-activating factor receptors. Role of phospholipase C beta3 phosphorylation by protein kinase A. J. Biol. Chem. 273:11012-11016.
31. Falk, W., R.H. Goodwin, Jr., and E.J. Leonard. 1980. A 48-well microchemotaxis assembly for rapid and accurate measurement of leukocyte migration. J. Immunol. Methods. 33: 239-247.
32. Gong, X., W. Gong, D.B. Kuhns, A. Ben-Baruch, O.M. Howard and J.M. Wang. 1997. Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors. J. Biol. Chem. 272:11682-11685.
33. Wang, J.M., D.W. McVicar, J.J. Oppenheim, and D.J. Kelvin. 1993. Identification of RANTES receptors on human monocytic cells: competition for binding and desensitization by homologous chemotactic cytokines. J. Exp. Med. 177:699-705.
34. Gong, W., O.M. Howard, J.A. Turpin, M.C. Grimm, P. Gray, C.J. Raport, J.J. Oppenheim, and J.M. Wang. 1998. Monocyte chemotactic protein (MCP)-2 activates CCR5 and blocks CD4/CCR5-mediated HIV-1 entry/replication. J. Biol. Chem. 273:4289-4292.
35. Ben-Baruch, A., L. Xu, P.R. Young, K. Bengali, J.J. Oppenheim, and J.M. Wang. 1995. Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3. J. Biol. Chem. 270:22123-22128.
36. Durstin, M., J.L. Gao, H.L. Tiffany, D. McDermott, and P.M. Murphy. 1994. Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes. Biochem. Biophys. Res. Commun. 201:174-179.
37. Samuelsson, B., S.E. Dahlen, J.A. Lindgren, C.A. Rouzer, and C.N. Serhan. 1987. Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science. 237:1171-1176.
38. Lee, T.H., P. Lympany, A.E. Crea, and B.W. Spur. 1991. Inhibition of leukotriene B4-induced neutrophil migration by lipoxin A4: structure-function relationships. Biochem. Biophys. Res. Commun. 180:1416-1421.
39. Ali, H., R.M. Richardson, E.D. Tomhave, J.R. Didsbury, and R. Snyderman. 1993. Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization. J. biol. Chem. 268:24247-24254.
40. Ali, H., E.D. Tomhave, R.M. Richardson, B. Haribabu, and R. Snyderman. 1996. Thrombin primes responsiveness of selective chemoattractant receptors at a site distal to G protein activation J. Biol. Chem. 271:3200-3206.
41. Linke, R.P., V. Bock, G. Valet, and G. Rothe. 1991. Inhibition of the oxidative burst response of N-formyl peptide-stimulated neutrophils by serum amyloid-A protein. Biochem. Biophys. Res. Commun. 176:1100-1105.
42. Steel, D.M., F.C. Donoghue, R.M. O'Neill, C.M. Uhlar, and A.S. Whitehead. 1996. Expression and regulation of constitutive and acute phase serum amyloid A mRNAs in hepatic and non-hepatic cell lines. Scand. J. Immunol. 44:493-500.
43. Liang, J., and J.D. Sipe. 1995. Recombinant human serum amyloid A (apoSAAp) binds cholesterol and modulates cholesterol flux. J. Lipid Res. 36:37-46.