Cigarette smoke inhibits engulfment of apoptotic cells by macrophages through inhibition of actin rearrangement

American Journal of Respiratory Cell and Molecular Biology

Volumn 44, Issue 4, 2011, Pages 474-482

  Minematsu, Naoto ^a,b   Blumental Perry, Anna ^c   Shapiro, Steven D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TUFTS MEDICAL CENTER   (United States)

Author keywords

Actin rearrangements; Alveolar macrophage; Cigarette smoke; Phagocytosis and engulfment of apoptotic cells; Small GTP protein Rac1

Indexed keywords

ACTIN; CELL SURFACE RECEPTOR; CIGARETTE SMOKE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAC1 PROTEIN; UNCLASSIFIED DRUG; VAV1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MEMBRANE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; ENZYME INACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHAGOCYTOSIS; POLYMORPHONUCLEAR CELL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTINS; ANIMALS; APOPTOSIS; CELL MOVEMENT; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MONOCYTES; NEUTROPHILS; PHAGOCYTOSIS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-VAV; PULMONARY ALVEOLI; RAC1 GTP-BINDING PROTEIN; SMOKING; TIME FACTORS;

EID: 79953738687     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2009-0463OC     Document Type: Article

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