-
1
-
-
24044527139
-
Activation of DNA damage signaling
-
Ljungman M. Activation of DNA damage signaling. Mutat Res 2005; 577: 203-216.
-
(2005)
Mutat Res
, vol.577
, pp. 203-216
-
-
Ljungman, M.1
-
2
-
-
84856019858
-
The DNA damage response and cancer therapy
-
Lord CJ, Ashworth A. The DNA damage response and cancer therapy. Nature 2012; 481: 287-294.
-
(2012)
Nature
, vol.481
, pp. 287-294
-
-
Lord, C.J.1
Ashworth, A.2
-
3
-
-
84869443686
-
Endogenous anticancer mechanisms (EACMs)
-
Lenz G. Endogenous anticancer mechanisms (EACMs). Front Biosci (Schol Ed) 2012; 4: 1017-1030.
-
(2012)
Front Biosci (Schol Ed)
, vol.4
, pp. 1017-1030
-
-
Lenz, G.1
-
4
-
-
78349266774
-
The DNA damage response-repair or despair?
-
Ljungman M. The DNA damage response-repair or despair? Environ Mol Mutagen 2010; 51: 879-889.
-
(2010)
Environ Mol Mutagen
, vol.51
, pp. 879-889
-
-
Ljungman, M.1
-
6
-
-
84872231223
-
The PI3K, metabolic, and autophagy networks: Interactive partners in cellular health and disease
-
Shanware NP, Bray K, Abraham RT. The PI3K, metabolic, and autophagy networks: interactive partners in cellular health and disease. Annu Rev Pharmacol Toxicol 2013; 53: 89-106.
-
(2013)
Annu Rev Pharmacol Toxicol
, vol.53
, pp. 89-106
-
-
Shanware, N.P.1
Bray, K.2
Abraham, R.T.3
-
7
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J, Kundu M, Viollet B, Guan KL. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat Cell Biol 2011; 13: 132-141.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
8
-
-
33846186410
-
Control of the autophagy maturation step by the MAPK ERK and p38: Lessons from environmental carcinogens
-
Corcelle E, Djerbi N, Mari M, Nebout M, Fiorini C, Fenichel P et al. Control of the autophagy maturation step by the MAPK ERK and p38: lessons from environmental carcinogens. Autophagy 2007; 3: 57-59.
-
(2007)
Autophagy
, vol.3
, pp. 57-59
-
-
Corcelle, E.1
Djerbi, N.2
Mari, M.3
Nebout, M.4
Fiorini, C.5
Fenichel, P.6
-
9
-
-
79959354999
-
Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
-
Green DR, Galluzzi L, Kroemer G. Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 2011; 333: 1109-1112.
-
(2011)
Science
, vol.333
, pp. 1109-1112
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
10
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-293.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
11
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
Singh R, Cuervo AM. Autophagy in the cellular energetic balance. Cell Metab 2011; 13: 495-504.
-
(2011)
Cell Metab
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
12
-
-
33847404337
-
Autophagy gene-dependent clearance of apoptotic cells during embryonic development
-
Qu X, Zou Z, Sun Q, Luby-Phelps K, Cheng P, Hogan RN et al. Autophagy gene-dependent clearance of apoptotic cells during embryonic development. Cell 2007; 128: 931-946.
-
(2007)
Cell
, vol.128
, pp. 931-946
-
-
Qu, X.1
Zou, Z.2
Sun, Q.3
Luby-Phelps, K.4
Cheng, P.5
Hogan, R.N.6
-
13
-
-
80052719816
-
Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death
-
Gao W, Shen Z, Shang L, Wang X. Upregulation of human autophagy-initiation kinase ULK1 by tumor suppressor p53 contributes to DNA-damage-induced cell death. Cell Death Differ 2011; 18: 1598-1607.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1598-1607
-
-
Gao, W.1
Shen, Z.2
Shang, L.3
Wang, X.4
-
14
-
-
33745885329
-
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
-
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126: 121-134.
-
(2006)
Cell
, vol.126
, pp. 121-134
-
-
Crighton, D.1
Wilkinson, S.2
O'Prey, J.3
Syed, N.4
Smith, P.5
Harrison, P.R.6
-
15
-
-
0022384018
-
Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats
-
Schwarze PE, Seglen PO. Reduced autophagic activity, improved protein balance and enhanced in vitro survival of hepatocytes isolated from carcinogen-treated rats. Exp Cell Res 1985; 157: 15-28.
-
(1985)
Exp Cell Res
, vol.157
, pp. 15-28
-
-
Schwarze, P.E.1
Seglen, P.O.2
-
16
-
-
0344142468
-
Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
-
Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E et al. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999; 59: 59-65.
-
(1999)
Genomics
, vol.59
, pp. 59-65
-
-
Aita, V.M.1
Liang, X.H.2
Murty, V.V.3
Pincus, D.L.4
Yu, W.5
Cayanis, E.6
-
17
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
Liang XH, Jackson S, Seaman M, Brown K, Kempkes B, Hibshoosh H et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 1999; 402: 672-676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
-
18
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
Qu X, Yu J, Bhagat G, Furuya N, Hibshoosh H, Troxel A et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 2003; 112: 1809-1820.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
-
19
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
-
Yue Z, Jin S, Yang C, Levine AJ, Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor. Proc Natl Acad Sci USA 2003; 100: 15077-15082.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
20
-
-
33745751085
-
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
-
Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH et al. Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 2006; 8: 688-699.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 688-699
-
-
Liang, C.1
Feng, P.2
Ku, B.3
Dotan, I.4
Canaani, D.5
Oh, B.H.6
-
21
-
-
34848899280
-
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
-
Takahashi Y, Coppola D, Matsushita N, Cualing HD, Sun M, Sato Y et al. Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis. Nat Cell Biol 2007; 9: 1142-1151.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1142-1151
-
-
Takahashi, Y.1
Coppola, D.2
Matsushita, N.3
Cualing, H.D.4
Sun, M.5
Sato, Y.6
-
22
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
23
-
-
34347404887
-
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
-
Karantza-Wadsworth V, Patel S, Kravchuk O, Chen G, Mathew R, Jin S et al. Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis. Genes Dev 2007; 21: 1621-1635.
-
(2007)
Genes Dev
, vol.21
, pp. 1621-1635
-
-
Karantza-Wadsworth, V.1
Patel, S.2
Kravchuk, O.3
Chen, G.4
Mathew, R.5
Jin, S.6
-
24
-
-
34249863298
-
Autophagy suppresses tumor progression by limiting chromosomal instability
-
Mathew R, Kongara S, Beaudoin B, Karp CM, Bray K, Degenhardt K et al. Autophagy suppresses tumor progression by limiting chromosomal instability. Genes Dev 2007; 21: 1367-1381.
-
(2007)
Genes Dev
, vol.21
, pp. 1367-1381
-
-
Mathew, R.1
Kongara, S.2
Beaudoin, B.3
Karp, C.M.4
Bray, K.5
Degenhardt, K.6
-
25
-
-
77957861637
-
Chromosome band 17q21 in breast cancer: Significant association between beclin 1 loss and HER2/NEU amplification
-
Negri T, Tarantino E, Orsenigo M, Reid JF, Gariboldi M, Zambetti M et al. Chromosome band 17q21 in breast cancer: significant association between beclin 1 loss and HER2/NEU amplification. Genes Chromosomes Cancer 2010; 49: 901-909.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 901-909
-
-
Negri, T.1
Tarantino, E.2
Orsenigo, M.3
Reid, J.F.4
Gariboldi, M.5
Zambetti, M.6
-
26
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp CM, Beaudoin B, Vuong N, Chen G, Chen HY et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009; 137: 1062-1075.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.M.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
Chen, H.Y.6
-
27
-
-
84859886931
-
Mitochondria and reactive oxygen species. Which role in physiology and pathology?
-
Lenaz G. Mitochondria and reactive oxygen species. Which role in physiology and pathology? Adv Exp Med Biol 2012; 942: 93-136.
-
(2012)
Adv Exp Med Biol
, vol.942
, pp. 93-136
-
-
Lenaz, G.1
-
28
-
-
18344366874
-
Role of mitochondria in oxidative stress and aging
-
Lenaz G, Bovina C, D'Aurelio M, Fato R, Formiggini G, Genova ML et al. Role of mitochondria in oxidative stress and aging. Ann N Y Acad Sci 2002; 959: 199-213.
-
(2002)
Ann N y Acad Sci
, vol.959
, pp. 199-213
-
-
Lenaz, G.1
Bovina, C.2
D'Aurelio, M.3
Fato, R.4
Formiggini, G.5
Genova, M.L.6
-
29
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler S, Holmstrom KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ et al. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol 2010; 12: 119-131.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrom, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
-
30
-
-
80355127945
-
Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes
-
Lee Y, Lee HY, Hanna RA, Gustafsson AB. Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes. Am J Physiol Heart Circ Physiol 2011; 301: H1924-H1931.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Lee, Y.1
Lee, H.Y.2
Hanna, R.A.3
Gustafsson, A.B.4
-
31
-
-
34250841750
-
Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12
-
Prigione A, Cortopassi G, Mitochondrial DNA. deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12. Autophagy 2007; 3: 377-380.
-
(2007)
Autophagy
, vol.3
, pp. 377-380
-
-
Prigione, A.1
Cortopassi, G.2
-
32
-
-
33751531893
-
Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript
-
Alemi M, Prigione A, Wong A, Schoenfeld R, DiMauro S, Hirano M et al. Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript. Free Radic Biol Med 2007; 42: 32-43.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 32-43
-
-
Alemi, M.1
Prigione, A.2
Wong, A.3
Schoenfeld, R.4
Dimauro, S.5
Hirano, M.6
-
33
-
-
34548627144
-
Mitochondrial DNA deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins
-
Prigione A, Cortopassi G, Mitochondrial DNA. deletions induce the adenosine monophosphate-activated protein kinase energy stress pathway and result in decreased secretion of some proteins. Aging Cell 2007; 6: 619-630.
-
(2007)
Aging Cell
, vol.6
, pp. 619-630
-
-
Prigione, A.1
Cortopassi, G.2
-
34
-
-
79952728102
-
The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance
-
Mortensen M, Soilleux EJ, Djordjevic G, Tripp R, Lutteropp M, Sadighi-Akha E et al. The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance. J Exp Med 2011; 208: 455-467.
-
(2011)
J Exp Med
, vol.208
, pp. 455-467
-
-
Mortensen, M.1
Soilleux, E.J.2
Djordjevic, G.3
Tripp, R.4
Lutteropp, M.5
Sadighi-Akha, E.6
-
35
-
-
80052382925
-
Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation
-
Mortensen M, Watson AS, Simon AK. Lack of autophagy in the hematopoietic system leads to loss of hematopoietic stem cell function and dysregulated myeloid proliferation. Autophagy 2011; 7: 1069-1070.
-
(2011)
Autophagy
, vol.7
, pp. 1069-1070
-
-
Mortensen, M.1
Watson, A.S.2
Simon, A.K.3
-
36
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
Takamura A, Komatsu M, Hara T, Sakamoto A, Kishi C, Waguri S et al. Autophagy-deficient mice develop multiple liver tumors. Genes Dev 2011; 25: 795-800.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
-
37
-
-
84255200364
-
Autophagy enhanced by microtubule-and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogen-esis
-
Xie R, Wang F, McKeehan WL, Liu L. Autophagy enhanced by microtubule-and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogen-esis. Cancer Res 2011; 71: 7537-7546.
-
(2011)
Cancer Res
, vol.71
, pp. 7537-7546
-
-
Xie, R.1
Wang, F.2
McKeehan, W.L.3
Liu, L.4
-
38
-
-
77952571717
-
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine
-
van Loon B, Markkanen E, Hubscher U. Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. DNA Repair (Amst) 2010; 9: 604-616.
-
(2010)
DNA Repair (Amst)
, vol.9
, pp. 604-616
-
-
Van Loon, B.1
Markkanen, E.2
Hubscher, U.3
-
39
-
-
55249116558
-
Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
-
Kinner A, Wu W, Staudt C, Iliakis G. Gamma-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin. Nucleic Acids Res 2008; 36: 5678-5694.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 5678-5694
-
-
Kinner, A.1
Wu, W.2
Staudt, C.3
Iliakis, G.4
-
40
-
-
84869011914
-
UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages
-
Greinert R, Volkmer B, Henning S, Breitbart EW, Greulich KO, Cardoso MC et al. UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages. Nucleic Acids Res 2012; 40: 10263-10273.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10263-10273
-
-
Greinert, R.1
Volkmer, B.2
Henning, S.3
Breitbart, E.W.4
Greulich, K.O.5
Cardoso, M.C.6
-
41
-
-
79956197636
-
Delayed repair of radiation induced clustered DNA damage: Friend or foe?
-
Eccles LJ, O'Neill P, Lomax ME. Delayed repair of radiation induced clustered DNA damage: friend or foe? Mutat Res 2011; 711: 134-141.
-
(2011)
Mutat Res
, vol.711
, pp. 134-141
-
-
Eccles, L.J.1
O'Neill, P.2
Lomax, M.E.3
-
42
-
-
84867474700
-
Oxidatively generated complex DNA damage: Tandem and clustered lesions
-
Cadet J, Ravanat JL, TavernaPorro M, Menoni H, Angelov D. Oxidatively generated complex DNA damage: tandem and clustered lesions. Cancer Lett 2012; 327: 5-15.
-
(2012)
Cancer Lett
, vol.327
, pp. 5-15
-
-
Cadet, J.1
Ravanat, J.L.2
Tavernaporro, M.3
Menoni, H.4
Angelov, D.5
-
43
-
-
33947327842
-
Oxidative stress overrides the spindle checkpoint
-
D'Angiolella V, Santarpia C, Grieco D. Oxidative stress overrides the spindle checkpoint. Cell Cycle 2007; 6: 576-579.
-
(2007)
Cell Cycle
, vol.6
, pp. 576-579
-
-
D'Angiolella, V.1
Santarpia, C.2
Grieco, D.3
-
44
-
-
84871981888
-
DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase
-
Dotiwala F, Eapen VV, Harrison JC, Arbel-Eden A, Ranade V, Yoshida S et al. DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase. Proc Natl Acad Sci USA 2013; 110: E41-E49.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
-
-
Dotiwala, F.1
Eapen, V.V.2
Harrison, J.C.3
Arbel-Eden, A.4
Ranade, V.5
Yoshida, S.6
-
45
-
-
80053564250
-
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
-
Kuo TC, Chen CT, Baron D, Onder TT, Loewer S, Almeida S et al. Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity. Nat Cell Biol 2011; 13: 1214-1223.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1214-1223
-
-
Kuo, T.C.1
Chen, C.T.2
Baron, D.3
Onder, T.T.4
Loewer, S.5
Almeida, S.6
-
46
-
-
79952270884
-
HDACs link the DNA damage response, processing of double-strand breaks and autophagy
-
Robert T, Vanoli F, Chiolo I, Shubassi G, Bernstein KA, Rothstein R et al. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature 2011; 471: 74-79.
-
(2011)
Nature
, vol.471
, pp. 74-79
-
-
Robert, T.1
Vanoli, F.2
Chiolo, I.3
Shubassi, G.4
Bernstein, K.A.5
Rothstein, R.6
-
47
-
-
33847008972
-
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
-
Katayama M, Kawaguchi T, Berger MS, Pieper RO. DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ 2007; 14: 548-558.
-
(2007)
Cell Death Differ
, vol.14
, pp. 548-558
-
-
Katayama, M.1
Kawaguchi, T.2
Berger, M.S.3
Pieper, R.O.4
-
48
-
-
79954549252
-
Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1
-
Dyavaiah M, Rooney JP, Chittur SV, Lin Q, Begley TJ. Autophagy-dependent regulation of the DNA damage response protein ribonucleotide reductase 1. Mol Cancer Res 2011; 9: 462-475.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 462-475
-
-
Dyavaiah, M.1
Rooney, J.P.2
Chittur, S.V.3
Lin, Q.4
Begley, T.J.5
-
49
-
-
51449084384
-
Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis
-
Ferraro E, Pulicati A, Cencioni MT, Cozzolino M, Navoni F, di Martino S et al. Apoptosome-deficient cells lose cytochrome c through proteasomal degradation but survive by autophagy-dependent glycolysis. Mol Biol Cell 2008; 19: 3576-3588.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3576-3588
-
-
Ferraro, E.1
Pulicati, A.2
Cencioni, M.T.3
Cozzolino, M.4
Navoni, F.5
Di Martino, S.6
-
50
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz JD, White E. Autophagy and metabolism. Science 2010; 330: 1344-1348.
-
(2010)
Science
, vol.330
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
52
-
-
34047268910
-
Chromatin remodeling in DNA double-strand break repair
-
Bao Y, Shen X. Chromatin remodeling in DNA double-strand break repair. Curr Opin Genet Dev 2007; 17: 126-131.
-
(2007)
Curr Opin Genet Dev
, vol.17
, pp. 126-131
-
-
Bao, Y.1
Shen, X.2
-
53
-
-
84863427300
-
ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy
-
Rodriguez-Vargas JM, Ruiz-Magana MJ, Ruiz-Ruiz C, Majuelos-Melguizo J, Peralta-Leal A, Rodriguez MI et al. ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy. Cell Res 2012; 22: 1181-1198.
-
(2012)
Cell Res
, vol.22
, pp. 1181-1198
-
-
Rodriguez-Vargas, J.M.1
Ruiz-Magana, M.J.2
Ruiz-Ruiz, C.3
Majuelos-Melguizo, J.4
Peralta-Leal, A.5
Rodriguez, M.I.6
-
54
-
-
58149380360
-
PARP-1 is involved in autophagy induced by DNA damage
-
Munoz-Gamez JA, Rodriguez-Vargas JM, Quiles-Perez R, Aguilar-Quesada R, Martin-Oliva D, de Murcia G et al. PARP-1 is involved in autophagy induced by DNA damage. Autophagy 2009; 5: 61-74.
-
(2009)
Autophagy
, vol.5
, pp. 61-74
-
-
Munoz-Gamez, J.A.1
Rodriguez-Vargas, J.M.2
Quiles-Perez, R.3
Aguilar-Quesada, R.4
Martin-Oliva, D.5
De Murcia, G.6
-
55
-
-
79952320889
-
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools
-
Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A. Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools. Nucleic Acids Res 2011; 39: 1360-1371.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 1360-1371
-
-
Kumar, D.1
Abdulovic, A.L.2
Viberg, J.3
Nilsson, A.K.4
Kunkel, T.A.5
Chabes, A.6
-
56
-
-
0038485588
-
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA)
-
Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C. Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). J Biol Chem 2003; 278: 12579-12589.
-
(2003)
J Biol Chem
, vol.278
, pp. 12579-12589
-
-
Henderson, C.1
Mizzau, M.2
Paroni, G.3
Maestro, R.4
Schneider, C.5
Brancolini, C.6
-
57
-
-
27544508549
-
Sirtuins (histone deacetylases III) in the cellular response to DNA damage-facts and hypotheses
-
Kruszewski M, Szumiel I. Sirtuins (histone deacetylases III) in the cellular response to DNA damage-facts and hypotheses. DNA Repair (Amst) 2005; 4: 1306-1313.
-
(2005)
DNA Repair (Amst)
, vol.4
, pp. 1306-1313
-
-
Kruszewski, M.1
Szumiel, I.2
-
58
-
-
84855424390
-
Interplay between histone deacetylases and autophagy-from cancer therapy to neurodegeneration
-
True O, Matthias P. Interplay between histone deacetylases and autophagy-from cancer therapy to neurodegeneration. Immunol Cell Biol 2012; 90: 78-84.
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 78-84
-
-
True, O.1
Matthias, P.2
-
59
-
-
43149090064
-
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
-
Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL et al. FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 2008; 181: 497-510.
-
(2008)
J Cell Biol
, vol.181
, pp. 497-510
-
-
Hara, T.1
Takamura, A.2
Kishi, C.3
Iemura, S.4
Natsume, T.5
Guan, J.L.6
-
60
-
-
80052841386
-
Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents
-
Bae H, Guan JL. Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents. Mol Cancer Res 2011; 9: 1232-1241.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1232-1241
-
-
Bae, H.1
Guan, J.L.2
-
61
-
-
71049127354
-
Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae
-
Moore DM, Karlin J, Gonzalez-Barrera S, Mardiros A, Lisby M, Doughty A et al. Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae. Nucleic Acids Res 2009; 37: 6429-6438.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 6429-6438
-
-
Moore, D.M.1
Karlin, J.2
Gonzalez-Barrera, S.3
Mardiros, A.4
Lisby, M.5
Doughty, A.6
-
62
-
-
78650884699
-
Macroautophagy-mediated degradation of whole nuclei in the filamentous fungus Aspergillus oryzae
-
Shoji JY, Kikuma T, Arioka M, Kitamoto K. Macroautophagy-mediated degradation of whole nuclei in the filamentous fungus Aspergillus oryzae. PLoS One 2010; 5: e15650.
-
(2010)
PLoS One
, vol.5
-
-
Shoji, J.Y.1
Kikuma, T.2
Arioka, M.3
Kitamoto, K.4
-
63
-
-
80955178805
-
Loss of intestinal nuclei and intestinal integrity in aging C elegans
-
McGee MD, Weber D, Day N, Vitelli C, Crippen D, Herndon LA et al. Loss of intestinal nuclei and intestinal integrity in aging C. elegans. Aging Cell 2011; 10: 699-710.
-
(2011)
Aging Cell
, vol.10
, pp. 699-710
-
-
McGee, M.D.1
Weber, D.2
Day, N.3
Vitelli, C.4
Crippen, D.5
Herndon, L.A.6
-
64
-
-
57349198328
-
Piecemeal microautophagy of the nucleus requires the core macroautophagy genes
-
Krick R, Muehe Y, Prick T, Bremer S, Schlotterhose P, Eskelinen EL et al. Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell 2008; 19: 4492-4505.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 4492-4505
-
-
Krick, R.1
Muehe, Y.2
Prick, T.3
Bremer, S.4
Schlotterhose, P.5
Eskelinen, E.L.6
-
65
-
-
24344449583
-
Targeting of Tsc13p to nucleus-vacuole junctions: A role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles
-
Kvam E, Gable K, Dunn TM, Goldfarb DS. Targeting of Tsc13p to nucleus-vacuole junctions: a role for very-long-chain fatty acids in the biogenesis of microautophagic vesicles. Mol Biol Cell 2005; 16: 3987-3998.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3987-3998
-
-
Kvam, E.1
Gable, K.2
Dunn, T.M.3
Goldfarb, D.S.4
-
67
-
-
58149382236
-
Measuring piecemeal microautophagy of the nucleus in Saccharomyces cerevisiae
-
Millen JI, Krick R, Prick T, Thumm M, Goldfarb DS. Measuring piecemeal microautophagy of the nucleus in Saccharomyces cerevisiae. Autophagy 2009; 5: 75-81.
-
(2009)
Autophagy
, vol.5
, pp. 75-81
-
-
Millen, J.I.1
Krick, R.2
Prick, T.3
Thumm, M.4
Goldfarb, D.S.5
-
68
-
-
69449083200
-
Autophagic degradation of nuclear components in mammalian cells
-
Park YE, Hayashi YK, Bonne G, Arimura T, Noguchi S, Nonaka I et al. Autophagic degradation of nuclear components in mammalian cells. Autophagy 2009; 5: 795-804.
-
(2009)
Autophagy
, vol.5
, pp. 795-804
-
-
Park, Y.E.1
Hayashi, Y.K.2
Bonne, G.3
Arimura, T.4
Noguchi, S.5
Nonaka, I.6
-
69
-
-
0032977685
-
Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy
-
Bonne G, Di Barletta MR, Varnous S, Becane HM, Hammouda EH, Merlini L et al. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nat Genet 1999; 21: 285-288.
-
(1999)
Nat Genet
, vol.21
, pp. 285-288
-
-
Bonne, G.1
Di Barletta, M.R.2
Varnous, S.3
Becane, H.M.4
Hammouda, E.H.5
Merlini, L.6
-
70
-
-
0037673950
-
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
-
Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L et al. Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 2003; 423: 293-298.
-
(2003)
Nature
, vol.423
, pp. 293-298
-
-
Eriksson, M.1
Brown, W.T.2
Gordon, L.B.3
Glynn, M.W.4
Singer, J.5
Scott, L.6
-
71
-
-
84855712059
-
Autophagic removal of micronuclei
-
Rello-Varona S, Lissa D, Shen S, Niso-Santano M, Senovilla L, Marino G et al. Autophagic removal of micronuclei. Cell Cycle 2012; 11: 170-176.
-
(2012)
Cell Cycle
, vol.11
, pp. 170-176
-
-
Rello-Varona, S.1
Lissa, D.2
Shen, S.3
Niso-Santano, M.4
Senovilla, L.5
Marino, G.6
-
72
-
-
77958498222
-
The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
-
Smith J, Tho LM, Xu N, Gillespie DA. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv Cancer Res 2010; 108: 73-112.
-
(2010)
Adv Cancer Res
, vol.108
, pp. 73-112
-
-
Smith, J.1
Tho, L.M.2
Xu, N.3
Gillespie, D.A.4
-
73
-
-
77955943918
-
Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response
-
Tichy A, Vavrova J, Pejchal J, Rezacova M. Ataxia-telangiectasia mutated kinase (ATM) as a central regulator of radiation-induced DNA damage response. Acta Medica (Hradec Kralove) 2010; 53: 13-17.
-
(2010)
Acta Medica (Hradec Kralove)
, vol.53
, pp. 13-17
-
-
Tichy, A.1
Vavrova, J.2
Pejchal, J.3
Rezacova, M.4
-
74
-
-
61349089240
-
P53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal
-
Batista LF, Roos WP, Kaina B, Menck CF. p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal. Mol Cancer Res 2009; 7: 237-246.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 237-246
-
-
Batista, L.F.1
Roos, W.P.2
Kaina, B.3
Menck, C.F.4
-
75
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH, Prives C. Blinded by the light: the growing complexity of p53. Cell 2009; 137: 413-431.
-
(2009)
Cell
, vol.137
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
76
-
-
50249145608
-
A dual role of p53 in the control of autophagy
-
Tasdemir E, Chiara Maiuri M, Morselli E, Criollo A, D'Amelio M, Djavaheri-Mergny M et al. A dual role of p53 in the control of autophagy. Autophagy 2008; 4: 810-814.
-
(2008)
Autophagy
, vol.4
, pp. 810-814
-
-
Tasdemir, E.1
Chiara Maiuri, M.2
Morselli, E.3
Criollo, A.4
D'Amelio, M.5
Djavaheri-Mergny, M.6
-
77
-
-
78650418176
-
P53 and autophagy in cancer: Guardian of the genome meets guardian of the proteome
-
Ryan KM. p53 and autophagy in cancer: guardian of the genome meets guardian of the proteome. Eur J Cancer 2011; 47: 44-50.
-
(2011)
Eur J Cancer
, vol.47
, pp. 44-50
-
-
Ryan, K.M.1
-
78
-
-
48449101433
-
P53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling
-
Budanov AV, Karin M. p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling. Cell 2008; 134: 451-460.
-
(2008)
Cell
, vol.134
, pp. 451-460
-
-
Budanov, A.V.1
Karin, M.2
-
79
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH et al. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci USA 2010; 107: 4153-4158.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
Nanez, A.4
Sahin, M.5
MacLean, K.H.6
-
80
-
-
53649086181
-
Mutant p53 protein localized in the cytoplasm inhibits autophagy
-
Morselli E, Tasdemir E, Maiuri MC, Galluzzi L, Kepp O, Criollo A et al. Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle 2008; 7: 3056-3061.
-
(2008)
Cell Cycle
, vol.7
, pp. 3056-3061
-
-
Morselli, E.1
Tasdemir, E.2
Maiuri, M.C.3
Galluzzi, L.4
Kepp, O.5
Criollo, A.6
-
81
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M et al. Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 2008; 10: 676-687.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 676-687
-
-
Tasdemir, E.1
Maiuri, M.C.2
Galluzzi, L.3
Vitale, I.4
Djavaheri-Mergny, M.5
D'Amelio, M.6
-
82
-
-
84862777879
-
Role of autophagy in chemoresistance: Regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1
-
Yoon JH, Ahn SG, Lee BH, Jung SH, Oh SH. Role of autophagy in chemoresistance: regulation of the ATM-mediated DNA-damage signaling pathway through activation of DNA-PKcs and PARP-1. Biochem Pharmacol 2012; 83: 747-757.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 747-757
-
-
Yoon, J.H.1
Ahn, S.G.2
Lee, B.H.3
Jung, S.H.4
Oh, S.H.5
-
83
-
-
77953286298
-
BNIP3 is essential for mediating 6-thioguanine-and 5-fluorouracil-induced autophagy following DNA mismatch repair processing
-
Zeng X, Kinsella TJ. BNIP3 is essential for mediating 6-thioguanine-and 5-fluorouracil-induced autophagy following DNA mismatch repair processing. Cell Res 20: 665-675.
-
Cell Res
, vol.20
, pp. 665-675
-
-
Zeng, X.1
Kinsella, T.J.2
-
84
-
-
42049095495
-
Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy
-
Zeng X, Kinsella TJ. Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. Cancer Res 2008; 68: 2384-2390.
-
(2008)
Cancer Res
, vol.68
, pp. 2384-2390
-
-
Zeng, X.1
Kinsella, T.J.2
-
85
-
-
77953529864
-
E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair
-
Guo R, Chen J, Zhu F, Biswas AK, Berton TR, Mitchell DL et al. E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair. J Biol Chem 2001; 285: 19308-19315.
-
(2001)
J Biol Chem
, vol.285
, pp. 19308-19315
-
-
Guo, R.1
Chen, J.2
Zhu, F.3
Biswas, A.K.4
Berton, T.R.5
Mitchell, D.L.6
-
86
-
-
0345099612
-
DNA damage induces transcriptional activation of p73 by removing C-EBPalpha repression on E2F1
-
Marabese M, Vikhanskaya F, Rainelli C, Sakai T, Broggini M. DNA damage induces transcriptional activation of p73 by removing C-EBPalpha repression on E2F1. Nucleic Acids Res 2003; 31: 6624-6632.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6624-6632
-
-
Marabese, M.1
Vikhanskaya, F.2
Rainelli, C.3
Sakai, T.4
Broggini, M.5
-
87
-
-
49649121765
-
E2F1 regulates autophagy and the transcription of autophagy genes
-
Polager S, Ofir M, Ginsberg D. E2F1 regulates autophagy and the transcription of autophagy genes. Oncogene 2008; 27: 4860-4864.
-
(2008)
Oncogene
, vol.27
, pp. 4860-4864
-
-
Polager, S.1
Ofir, M.2
Ginsberg, D.3
-
88
-
-
77951536199
-
ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy
-
Eby KG, Rosenbluth JM, Mays DJ, Marshall CB, Barton CE, Sinha S et al. ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. Mol Cancer 2010; 9: 95.
-
(2010)
Mol Cancer
, vol.9
, pp. 95
-
-
Eby, K.G.1
Rosenbluth, J.M.2
Mays, D.J.3
Marshall, C.B.4
Barton, C.E.5
Sinha, S.6
-
89
-
-
34249056243
-
P73 regulates DRAM-independent autophagy that does not contribute to programmed cell death
-
Crighton D, O'Prey J, Bell HS, Ryan KM. p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death. Cell Death Differ 2007; 14: 1071-1079.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1071-1079
-
-
Crighton, D.1
O'Prey, J.2
Bell, H.S.3
Ryan, K.M.4
-
90
-
-
0041997348
-
Chemosensitivity linked to p73 function
-
Irwin MS, Kondo K, Marin MC, Cheng LS, Hahn WC, Kaelin WG Jr. Chemosensitivity linked to p73 function. Cancer Cell 2003; 3: 403-410.
-
(2003)
Cancer Cell
, vol.3
, pp. 403-410
-
-
Irwin, M.S.1
Kondo, K.2
Marin, M.C.3
Cheng, L.S.4
Hahn, W.C.5
Kaelin Jr., W.G.6
-
91
-
-
82655171629
-
P73 protein regulates DNA damage repair
-
Zaika E, Wei J, Yin D, Andl C, Moll U, El-Rifai W et al. p73 protein regulates DNA damage repair. FASEB J 2011; 25: 4406-4414.
-
(2011)
FASEB J
, vol.25
, pp. 4406-4414
-
-
Zaika, E.1
Wei, J.2
Yin, D.3
Andl, C.4
Moll, U.5
El-Rifai, W.6
-
92
-
-
0033379005
-
P53 family genes: Structural comparison, expression and mutation
-
Ikawa S, Nakagawara A, Ikawa Y. p53 family genes: structural comparison, expression and mutation. Cell Death Differ 1999; 6: 1154-1161.
-
(1999)
Cell Death Differ
, vol.6
, pp. 1154-1161
-
-
Ikawa, S.1
Nakagawara, A.2
Ikawa, Y.3
-
93
-
-
77953529864
-
E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair
-
Guo R, Chen J, Zhu F, Biswas AK, Berton TR, Mitchell DL et al. E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair. J Biol Chem 2010; 285: 19308-19315.
-
(2010)
J Biol Chem
, vol.285
, pp. 19308-19315
-
-
Guo, R.1
Chen, J.2
Zhu, F.3
Biswas, A.K.4
Berton, T.R.5
Mitchell, D.L.6
-
94
-
-
78149475088
-
Regulation of mammalian autophagy in physiology and pathophysiology
-
Ravikumar B, Sarkar S, Davies JE, Futter M, Garcia-Arencibia M, Green-Thompson ZW et al. Regulation of mammalian autophagy in physiology and pathophysiology. Physiol Rev 2010; 90: 1383-1435.
-
(2010)
Physiol Rev
, vol.90
, pp. 1383-1435
-
-
Ravikumar, B.1
Sarkar, S.2
Davies, J.E.3
Futter, M.4
Garcia-Arencibia, M.5
Green-Thompson, Z.W.6
-
95
-
-
77957654940
-
Autophagic degradation of active caspase-8: A crosstalk mechanism between autophagy and apoptosis
-
Hou W, Han J, Lu C, Goldstein LA, Rabinowich H. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy 2010; 6: 891-900.
-
(2010)
Autophagy
, vol.6
, pp. 891-900
-
-
Hou, W.1
Han, J.2
Lu, C.3
Goldstein, L.A.4
Rabinowich, H.5
-
96
-
-
84872733519
-
Autophagy controls p38 activation to promote cell survival under genotoxic stress
-
Qiang L, Wu C, Ming M, Viollet B, He YY. Autophagy controls p38 activation to promote cell survival under genotoxic stress. J Biol Chem 2013; 288: 1603-1611.
-
(2013)
J Biol Chem
, vol.288
, pp. 1603-1611
-
-
Qiang, L.1
Wu, C.2
Ming, M.3
Viollet, B.4
He, Y.Y.5
-
97
-
-
80053635472
-
Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect
-
Zhang C, Lin M, Wu R, Wang X, Yang B, Levine AJ et al. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc Natl Acad Sci USA 2011; 108: 16259-16264.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16259-16264
-
-
Zhang, C.1
Lin, M.2
Wu, R.3
Wang, X.4
Yang, B.5
Levine, A.J.6
-
98
-
-
77955903343
-
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
-
Nezis IP, Shravage BV, Sagona AP, Lamark T, Bjorkoy G, Johansen T et al. Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis. J Cell Biol 2010; 190: 523-531.
-
(2010)
J Cell Biol
, vol.190
, pp. 523-531
-
-
Nezis, I.P.1
Shravage, B.V.2
Sagona, A.P.3
Lamark, T.4
Bjorkoy, G.5
Johansen, T.6
-
99
-
-
33645521571
-
Autophagic programmed cell death by selective catalase degradation
-
Yu L, Wan F, Dutta S, Welsh S, Liu Z, Freundt E et al. Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci USA 2006; 103: 4952-4957.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 4952-4957
-
-
Yu, L.1
Wan, F.2
Dutta, S.3
Welsh, S.4
Liu, Z.5
Freundt, E.6
-
100
-
-
84860914325
-
Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1
-
Siggens L, Figg N, Bennett M, Foo R. Nutrient deprivation regulates DNA damage repair in cardiomyocytes via loss of the base-excision repair enzyme OGG1. FASEB J 2012; 26: 2117-2124.
-
(2012)
FASEB J
, vol.26
, pp. 2117-2124
-
-
Siggens, L.1
Figg, N.2
Bennett, M.3
Foo, R.4
-
101
-
-
69249153394
-
A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1
-
Wang J, Whiteman MW, Lian H, Wang G, Singh A, Huang D et al. A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1. J Biol Chem 2009; 284: 21412-21424.
-
(2009)
J Biol Chem
, vol.284
, pp. 21412-21424
-
-
Wang, J.1
Whiteman, M.W.2
Lian, H.3
Wang, G.4
Singh, A.5
Huang, D.6
-
102
-
-
34848845834
-
Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells
-
Wang ZH, Xu L, Duan ZL, Zeng LQ, Yan NH, Peng ZL. Beclin 1-mediated macroautophagy involves regulation of caspase-9 expression in cervical cancer HeLa cells. Gynecol Oncol 2007; 107: 107-113.
-
(2007)
Gynecol Oncol
, vol.107
, pp. 107-113
-
-
Zh, W.1
Xu, L.2
Duan, Z.L.3
Zeng, L.Q.4
Yan, N.H.5
Peng, Z.L.6
-
103
-
-
79957458183
-
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease
-
Nascimento-Ferreira I, Santos-Ferreira T, Sousa-Ferreira L, Auregan G, Onofre I, Alves S et al. Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease. Brain 2011; 134(Pt 5): 1400-1415.
-
(2011)
Brain
, vol.134
, Issue.PART 5
, pp. 1400-1415
-
-
Nascimento-Ferreira, I.1
Santos-Ferreira, T.2
Sousa-Ferreira, L.3
Auregan, G.4
Onofre, I.5
Alves, S.6
-
105
-
-
84861083651
-
Implications of therapy-induced selective autophagy on tumor metabolism and survival
-
Hughson LR, Poon VI, Spowart JE, Lum JJ. Implications of therapy-induced selective autophagy on tumor metabolism and survival. Int J Cell Biol 2012; 2012: 872091.
-
(2012)
Int J Cell Biol
, vol.2012
, pp. 872091
-
-
Hughson, L.R.1
Poon, V.I.2
Spowart, J.E.3
Lum, J.J.4
-
106
-
-
45449093552
-
The role of Cockayne Syndrome group. B (CSB) protein in base excision repair and aging
-
Stevnsner T, Muftuoglu M, Aamann MD, Bohr VA. The role of Cockayne Syndrome group. B (CSB) protein in base excision repair and aging. Mech Ageing Dev 2008; 129: 441-448.
-
(2008)
Mech Ageing Dev
, vol.129
, pp. 441-448
-
-
Stevnsner, T.1
Muftuoglu, M.2
Aamann, M.D.3
Bohr, V.A.4
-
107
-
-
0037069933
-
Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B
-
Stevnsner T, Nyaga S, de Souza-Pinto NC, van der Horst GT, Gorgels TG, Hogue BA et al. Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B. Oncogene 2002; 21: 8675-8682.
-
(2002)
Oncogene
, vol.21
, pp. 8675-8682
-
-
Stevnsner, T.1
Nyaga, S.2
De Souza-Pinto, N.C.3
Van Der Horst, G.T.4
Gorgels, T.G.5
Hogue, B.A.6
-
108
-
-
77954436746
-
Cockayne syndrome group. B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane
-
Aamann MD, Sorensen MM, Hvitby C, Berquist BR, Muftuoglu M, Tian J et al. Cockayne syndrome group. B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane. FASEB J 2010; 24: 2334-2346.
-
(2010)
FASEB J
, vol.24
, pp. 2334-2346
-
-
Aamann, M.D.1
Sorensen, M.M.2
Hvitby, C.3
Berquist, B.R.4
Muftuoglu, M.5
Tian, J.6
-
109
-
-
84861749572
-
Cockayne syndrome group. B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
-
Scheibye-Knudsen M, Ramamoorthy M, Sykora P, Maynard S, Lin PC, Minor RK et al. Cockayne syndrome group. B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. J Exp Med 2012; 209: 855-869.
-
(2012)
J Exp Med
, vol.209
, pp. 855-869
-
-
Scheibye-Knudsen, M.1
Ramamoorthy, M.2
Sykora, P.3
Maynard, S.4
Lin, P.C.5
Minor, R.K.6
-
110
-
-
84857489373
-
Autophagy in stem cell maintenance and differentiation
-
Vessoni AT, Muotri AR, Okamoto OK. Autophagy in stem cell maintenance and differentiation. Stem Cells Dev 2012; 21: 513-520.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 513-520
-
-
Vessoni, A.T.1
Muotri, A.R.2
Okamoto, O.K.3
-
111
-
-
84882580448
-
Functional dysregulation of stem cells during aging: A focus on skeletal muscle stem cells
-
e-pub ahead of print 2 March 2013, doi:10.1111/febs.12221
-
Garcia-Prat L, Sousa-Victor P, Munoz-Canoves P. Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells. FEBS J 2013; e-pub ahead of print 2 March 2013; doi:10.1111/febs.12221.
-
(2013)
FEBS J
-
-
Garcia-Prat, L.1
Sousa-Victor, P.2
Munoz-Canoves, P.3
-
112
-
-
33846561222
-
The role of oxidative stress in the pathogenesis of Alzheimer's disease
-
Filipcik P, Cente M, Ferencik M, Hulin I, Novak M. The role of oxidative stress in the pathogenesis of Alzheimer's disease. Bratisl Lek Listy 2006; 107: 384-394.
-
(2006)
Bratisl Lek Listy
, vol.107
, pp. 384-394
-
-
Filipcik, P.1
Cente, M.2
Ferencik, M.3
Hulin, I.4
Novak, M.5
-
114
-
-
79956048660
-
Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models
-
Khandelwal PJ, Herman AM, Hoe HS, Rebeck GW, Moussa CE. Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models. Hum Mol Genet 2011; 20: 2091-2102.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2091-2102
-
-
Khandelwal, P.J.1
Herman, A.M.2
Hoe, H.S.3
Rebeck, G.W.4
Moussa, C.E.5
-
115
-
-
68949129378
-
DNA damage induces nuclear translocation of parkin
-
Kao SY. DNA damage induces nuclear translocation of parkin. J Biomed Sci 2009; 16: 67.
-
(2009)
J Biomed Sci
, vol.16
, pp. 67
-
-
Kao, S.Y.1
-
116
-
-
63349087613
-
Regulation of DNA repair by parkin
-
Kao SY. Regulation of DNA repair by parkin. Biochem Biophys Res Commun 2009; 382: 321-325.
-
(2009)
Biochem Biophys Res Commun
, vol.382
, pp. 321-325
-
-
Kao, S.Y.1
-
117
-
-
80053243942
-
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
-
Majumder S, Richardson A, Strong R, Oddo S. Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. PLoS One 2011; 6: e25416.
-
(2011)
PLoS One
, vol.6
-
-
Majumder, S.1
Richardson, A.2
Strong, R.3
Oddo, S.4
-
118
-
-
80052256155
-
Mitophagy and disease: New avenues for pharmacological intervention
-
Taylor R, Goldman SJ. Mitophagy and disease: new avenues for pharmacological intervention. Curr Pharm Des 17: 2056-2073.
-
Curr Pharm des
, vol.17
, pp. 2056-2073
-
-
Taylor, R.1
Goldman, S.J.2
-
119
-
-
1242296021
-
Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability
-
Ionov Y, Nowak N, Perucho M, Markowitz S, Cowell JK. Manipulation of nonsense mediated decay identifies gene mutations in colon cancer cells with microsatellite instability. Oncogene 2004; 23: 639-645.
-
(2004)
Oncogene
, vol.23
, pp. 639-645
-
-
Ionov, Y.1
Nowak, N.2
Perucho, M.3
Markowitz, S.4
Cowell, J.K.5
-
120
-
-
64549101639
-
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
-
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS et al. Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability. J Pathol 2009; 217: 702-706.
-
(2009)
J Pathol
, vol.217
, pp. 702-706
-
-
Kang, M.R.1
Kim, M.S.2
Oh, J.E.3
Kim, Y.R.4
Song, S.Y.5
Kim, S.S.6
-
121
-
-
45049083880
-
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
-
Kim MS, Jeong EG, Ahn CH, Kim SS, Lee SH, Yoo NJ. Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability. Hum Pathol 2008; 39: 1059-1063.
-
(2008)
Hum Pathol
, vol.39
, pp. 1059-1063
-
-
Kim, M.S.1
Jeong, E.G.2
Ahn, C.H.3
Kim, S.S.4
Lee, S.H.5
Yoo, N.J.6
-
122
-
-
57649184088
-
Control of autophagy by oncogenes and tumor suppressor genes
-
Maiuri MC, Tasdemir E, Criollo A, Morselli E, Vicencio JM, Carnuccio R et al. Control of autophagy by oncogenes and tumor suppressor genes. Cell Death Differ 2009; 16: 87-93.
-
(2009)
Cell Death Differ
, vol.16
, pp. 87-93
-
-
Maiuri, M.C.1
Tasdemir, E.2
Criollo, A.3
Morselli, E.4
Vicencio, J.M.5
Carnuccio, R.6
-
123
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
Marino G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 2007; 282: 18573-18583.
-
(2007)
J Biol Chem
, vol.282
, pp. 18573-18583
-
-
Marino, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
Lopez-Otin, C.6
-
124
-
-
84860918805
-
A dual role for UVRAG in maintaining chromosomal stability independent of autophagy
-
Zhao Z, Oh S, Li D, Ni D, Pirooz SD, Lee JH et al. A dual role for UVRAG in maintaining chromosomal stability independent of autophagy. Dev Cell 2012; 22: 1001-1016.
-
(2012)
Dev Cell
, vol.22
, pp. 1001-1016
-
-
Zhao, Z.1
Oh, S.2
Li, D.3
Ni, D.4
Pirooz, S.D.5
Lee, J.H.6
-
125
-
-
78449273851
-
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
-
Knaevelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA et al. UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy. Autophagy 2010; 6: 863-870.
-
(2010)
Autophagy
, vol.6
, pp. 863-870
-
-
Knaevelsrud, H.1
Ahlquist, T.2
Merok, M.A.3
Nesbakken, A.4
Stenmark, H.5
Lothe, R.A.6
-
126
-
-
84255177532
-
Who put the A&in Atg12: Autophagy or apoptosis?
-
Ni Chonghaile T, Letai A. Who put the "A" in Atg12: autophagy or apoptosis? Mol Cell 2011; 44: 844-845.
-
(2011)
Mol Cell
, vol.44
, pp. 844-845
-
-
Ni Chonghaile, T.1
Letai, A.2
-
127
-
-
65949083750
-
Cytoplasmic functions of the tumour suppressor p53
-
Green DR, Kroemer G. Cytoplasmic functions of the tumour suppressor p53. Nature 2009; 458: 1127-1130.
-
(2009)
Nature
, vol.458
, pp. 1127-1130
-
-
Green, D.R.1
Kroemer, G.2
-
128
-
-
58149478492
-
MTOR regulates autophagy-associated genes downstream of p73
-
Rosenbluth JM, Pietenpol JA. mTOR regulates autophagy-associated genes downstream of p73. Autophagy 2009; 5: 114-116.
-
(2009)
Autophagy
, vol.5
, pp. 114-116
-
-
Rosenbluth, J.M.1
Pietenpol, J.A.2
-
129
-
-
0025264931
-
Isolation by polymerase chain reaction of a cDNA whose product partially complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells
-
Teitz T, Penner M, Eli D, Stark M, Bakhanashvili M, Naiman T et al. Isolation by polymerase chain reaction of a cDNA whose product partially complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells. Gene 1990; 87: 295-298.
-
(1990)
Gene
, vol.87
, pp. 295-298
-
-
Teitz, T.1
Penner, M.2
Eli, D.3
Stark, M.4
Bakhanashvili, M.5
Naiman, T.6
-
130
-
-
84855394410
-
Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage
-
Biswas AK, Johnson DG. Transcriptional and nontranscriptional functions of E2F1 in response to DNA damage. Cancer Res 2012; 72: 13-17.
-
(2012)
Cancer Res
, vol.72
, pp. 13-17
-
-
Biswas, A.K.1
Johnson, D.G.2
-
131
-
-
3242880237
-
The emerging role of E2F-1 in the DNA damage response and checkpoint control
-
Stevens C, La Thangue NB. The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair (Amst) 2004; 3: 1071-1079.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1071-1079
-
-
Stevens, C.1
La Thangue, N.B.2
-
132
-
-
79551473364
-
Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
-
Chen LH, Loong CC, Su TL, Lee YJ, Chu PM, Tsai ML et al. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway. Biochem Pharmacol 2011; 81: 594-605.
-
(2011)
Biochem Pharmacol
, vol.81
, pp. 594-605
-
-
Chen, L.H.1
Loong, C.C.2
Su, T.L.3
Lee, Y.J.4
Chu, P.M.5
Tsai, M.L.6
-
133
-
-
79960703030
-
Poly(ADP-ribose) polymerase-1 inhibition: Preclinical and clinical development of synthetic lethality
-
Leung M, Rosen D, Fields S, Cesano A, Budman DR. Poly(ADP-ribose) polymerase-1 inhibition: preclinical and clinical development of synthetic lethality. Mol Med 2011; 17: 854-862.
-
(2011)
Mol Med
, vol.17
, pp. 854-862
-
-
Leung, M.1
Rosen, D.2
Fields, S.3
Cesano, A.4
Budman, D.R.5
-
134
-
-
80053966336
-
The role of PARP in DNA repair and its therapeutic exploitation
-
Javle M, Curtin NJ. The role of PARP in DNA repair and its therapeutic exploitation. Br J Cancer 2011; 105: 1114-1122.
-
(2011)
Br J Cancer
, vol.105
, pp. 1114-1122
-
-
Javle, M.1
Curtin, N.J.2
-
135
-
-
84865085680
-
DNA damage and repair in human cancer: Molecular mechanisms and contribution to therapy-related leukemias
-
Casorelli I, Bossa C, Bignami M. DNA damage and repair in human cancer: molecular mechanisms and contribution to therapy-related leukemias. Int J Environ Res Public Health 2012; 9: 2636-2657.
-
(2012)
Int J Environ Res Public Health
, vol.9
, pp. 2636-2657
-
-
Casorelli, I.1
Bossa, C.2
Bignami, M.3
-
136
-
-
33947209622
-
DNA mismatch repair initiates 6-thioguanine-induced autophagy through p53 activation in human tumor cells
-
Zeng X, Yan T, Schupp JE, Seo Y, Kinsella TJ. DNA mismatch repair initiates 6-thioguanine-induced autophagy through p53 activation in human tumor cells. Clin Cancer Res 2007; 13: 1315-1321.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1315-1321
-
-
Zeng, X.1
Yan, T.2
Schupp, J.E.3
Seo, Y.4
Kinsella, T.J.5
-
137
-
-
84873830422
-
Survival and death strategies in glioma cells: Autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage
-
Knizhnik AV, Roos WP, Nikolova T, Quiros S, Tomaszowski KH, Christmann M et al. Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage. PLoS One 2013; 8: e55665.
-
(2013)
PLoS One
, vol.8
-
-
Knizhnik, A.V.1
Roos, W.P.2
Nikolova, T.3
Quiros, S.4
Tomaszowski, K.H.5
Christmann, M.6
-
138
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI et al. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 2007; 117: 326-336.
-
(2007)
J Clin Invest
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
-
139
-
-
79960058652
-
5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells
-
Shin SY, Hyun J, Yu JR, Lim Y, Lee YH. 5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells. Toxicol Appl Pharmacol 2011; 254: 288-298.
-
(2011)
Toxicol Appl Pharmacol
, vol.254
, pp. 288-298
-
-
Shin, S.Y.1
Hyun, J.2
Yu, J.R.3
Lim, Y.4
Lee, Y.H.5
|