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Volumn 327, Issue 1-2, 2012, Pages 5-15

Oxidatively generated complex DNA damage: Tandem and clustered lesions

Author keywords

DNA repair; DNA single and double strand breaks; Interstrand cross links; Intrastrand cross links; Ionizing radiation; Mutagenesis; Oxidative stress; Purine 5',8 cyclonucleosides; Tandem base lesions

Indexed keywords

AZATHIOPRINE; HYDROXYL RADICAL; MERCAPTOPURINE; NUCLEOSIDE DERIVATIVE; ONE ELECTRON OXIDANT; OXIDIZING AGENT; PEROXY RADICAL; PURINE 5',8 CYCLONUCLEOSIDE; PYRIMIDINE; REACTIVE OXYGEN METABOLITE; TIOGUANINE; UNCLASSIFIED DRUG;

EID: 84867474700     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.04.005     Document Type: Review
Times cited : (185)

References (186)
  • 1
    • 79956196320 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) - induced genetic and epigenetic alterations in human carcinogenesis
    • Ziech D., Franco R., Pappa A., Panayiotidis M.I. Reactive oxygen species (ROS) - induced genetic and epigenetic alterations in human carcinogenesis. Mutat. Res. 2011, 711:167-173.
    • (2011) Mutat. Res. , vol.711 , pp. 167-173
    • Ziech, D.1    Franco, R.2    Pappa, A.3    Panayiotidis, M.I.4
  • 2
    • 79951518607 scopus 로고    scopus 로고
    • Molecular targets of oxidative stress
    • Avery S.V. Molecular targets of oxidative stress. Biochem. J. 2011, 434:201-210.
    • (2011) Biochem. J. , vol.434 , pp. 201-210
    • Avery, S.V.1
  • 4
    • 77955267142 scopus 로고    scopus 로고
    • Chronic inflammation and mutagenesis
    • Ferguson L.R. Chronic inflammation and mutagenesis. Mutat. Res. 2010, 690:3-11.
    • (2010) Mutat. Res. , vol.690 , pp. 3-11
    • Ferguson, L.R.1
  • 5
    • 78649364685 scopus 로고    scopus 로고
    • Oxidative stress and inducible nitric oxide synthase induction in carcinogenesis
    • Fannati F., Piciocchi M., Lavezzo E., Bortolami M., Cardin R. Oxidative stress and inducible nitric oxide synthase induction in carcinogenesis. Dig. Dis. 2010, 28:579-584.
    • (2010) Dig. Dis. , vol.28 , pp. 579-584
    • Fannati, F.1    Piciocchi, M.2    Lavezzo, E.3    Bortolami, M.4    Cardin, R.5
  • 6
    • 79952474331 scopus 로고    scopus 로고
    • Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates
    • Lonkar P., Dedon P.C. Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates. Int. J. Cancer 2011, 128:1999-2009.
    • (2011) Int. J. Cancer , vol.128 , pp. 1999-2009
    • Lonkar, P.1    Dedon, P.C.2
  • 7
    • 80051667908 scopus 로고    scopus 로고
    • Exercise-induced oxidative stress in humans: cause and consequences
    • Powers S.K., Nelson W.B., Hudson M.B. Exercise-induced oxidative stress in humans: cause and consequences. Free Radic. Biol. Med. 2011, 51:942-950.
    • (2011) Free Radic. Biol. Med. , vol.51 , pp. 942-950
    • Powers, S.K.1    Nelson, W.B.2    Hudson, M.B.3
  • 8
    • 79954642381 scopus 로고    scopus 로고
    • Advances in metal-induced oxidative stress and human disease
    • Jomova K., Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology 2011, 283:65-87.
    • (2011) Toxicology , vol.283 , pp. 65-87
    • Jomova, K.1    Valko, M.2
  • 11
    • 78650751290 scopus 로고    scopus 로고
    • Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus
    • Takayanagi R., Inoguchi T., Ohnaka K. Clinical and experimental evidence for oxidative stress as an exacerbating factor of diabetes mellitus. J. Clin. Biochem. Nutr. 2011, 48:72-77.
    • (2011) J. Clin. Biochem. Nutr. , vol.48 , pp. 72-77
    • Takayanagi, R.1    Inoguchi, T.2    Ohnaka, K.3
  • 12
    • 77953415757 scopus 로고    scopus 로고
    • Oxidative stress as a mediator of cardiovascular disease
    • Elahi M.M., Kong Y.X., Matata B.M. Oxidative stress as a mediator of cardiovascular disease. Oxid. Med. Cell. Longev. 2009, 2:259-269.
    • (2009) Oxid. Med. Cell. Longev. , vol.2 , pp. 259-269
    • Elahi, M.M.1    Kong, Y.X.2    Matata, B.M.3
  • 13
    • 80051548139 scopus 로고    scopus 로고
    • Vascular-derived reactive oxygen species for homeostasis and diseases
    • Satoh K., Berk B.C., Shimokawa H. Vascular-derived reactive oxygen species for homeostasis and diseases. Nitric Oxide 2011, 25:211-215.
    • (2011) Nitric Oxide , vol.25 , pp. 211-215
    • Satoh, K.1    Berk, B.C.2    Shimokawa, H.3
  • 14
    • 80053110019 scopus 로고    scopus 로고
    • Oxidatively modified nucleic acids in preclinical Alzheimer's diseases (PCAD) brain
    • Lovell M.A., Soman S., Bradley M.A. Oxidatively modified nucleic acids in preclinical Alzheimer's diseases (PCAD) brain. Mech. Ageing Dev. 2011, 132:443-448.
    • (2011) Mech. Ageing Dev. , vol.132 , pp. 443-448
    • Lovell, M.A.1    Soman, S.2    Bradley, M.A.3
  • 15
    • 80054863696 scopus 로고    scopus 로고
    • Parkinson's disease and cancer: two wars, one front
    • Devine M.J., Plun-Favreau H., Wood N.W. Parkinson's disease and cancer: two wars, one front. Nat. Rev. Cancer 2011, 11:812-823.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 812-823
    • Devine, M.J.1    Plun-Favreau, H.2    Wood, N.W.3
  • 16
    • 48849114365 scopus 로고    scopus 로고
    • Molecular mechanisms of oxidative stress-induced carcinogenesis: from epidemiology to oxygenomics
    • Toyokuni S. Molecular mechanisms of oxidative stress-induced carcinogenesis: from epidemiology to oxygenomics. IUBMB Life 2008, 60:441-447.
    • (2008) IUBMB Life , vol.60 , pp. 441-447
    • Toyokuni, S.1
  • 18
    • 79956191022 scopus 로고    scopus 로고
    • Role of oxidative stress and DNA damage in human carcinogenesis
    • Kryston T.B., Georgiev A.B., Pissi P., Georgakilas A.G. Role of oxidative stress and DNA damage in human carcinogenesis. Mutat. Res. 2011, 711:193-201.
    • (2011) Mutat. Res. , vol.711 , pp. 193-201
    • Kryston, T.B.1    Georgiev, A.B.2    Pissi, P.3    Georgakilas, A.G.4
  • 19
    • 79959963304 scopus 로고    scopus 로고
    • Oxidative stresss and oxidative damage in chemical carcinogenesis
    • Klaunig J.E., Wang Z., Pu X., Zhou S. Oxidative stresss and oxidative damage in chemical carcinogenesis. Toxicol. Appl. Pharmacol. 2011, 254:86-99.
    • (2011) Toxicol. Appl. Pharmacol. , vol.254 , pp. 86-99
    • Klaunig, J.E.1    Wang, Z.2    Pu, X.3    Zhou, S.4
  • 20
    • 84867474710 scopus 로고    scopus 로고
    • PIG3: a novel link between oxidative stress and DNA damage response in cancer
    • A. Kotsinas, V. Aggarwal, E.-J. Tan, B. Levy, V.G. Gorgoulis, PIG3: a novel link between oxidative stress and DNA damage response in cancer, Cancer Lett., (2012), http://dx.doi.org/10.1016/J.canlet.2011.12.009.
    • (2012) Cancer Lett.
    • Kotsinas, A.1    Aggarwal, V.2    Tan, E.-J.3    Levy, B.4    Gorgoulis, V.G.5
  • 22
    • 84855374194 scopus 로고    scopus 로고
    • A model of the cell nucleus for DNA damage calculations
    • Nikjoo H., Girard P. A model of the cell nucleus for DNA damage calculations. Int. J. Radiat. Biol. 2012, 88:87-97.
    • (2012) Int. J. Radiat. Biol. , vol.88 , pp. 87-97
    • Nikjoo, H.1    Girard, P.2
  • 23
    • 14644433816 scopus 로고    scopus 로고
    • Ultraviolet radiation-mediated damage to cellular DNA
    • Cadet J., Douki T., Sage E. Ultraviolet radiation-mediated damage to cellular DNA. Mutat. Res. 2005, 571:3-17.
    • (2005) Mutat. Res. , vol.571 , pp. 3-17
    • Cadet, J.1    Douki, T.2    Sage, E.3
  • 24
    • 84255197177 scopus 로고    scopus 로고
    • DNA damage spectra induced by photosensitization
    • Epe B. DNA damage spectra induced by photosensitization. Photochem. Photobiol. Sci. 2011, 11:98-106.
    • (2011) Photochem. Photobiol. Sci. , vol.11 , pp. 98-106
    • Epe, B.1
  • 26
    • 33747163550 scopus 로고    scopus 로고
    • Guanine oxidation: one- and two-electron reactions
    • Pratviel G., Meunier B. Guanine oxidation: one- and two-electron reactions. Chemistry 2006, 12:6018-6030.
    • (2006) Chemistry , vol.12 , pp. 6018-6030
    • Pratviel, G.1    Meunier, B.2
  • 27
    • 51649086880 scopus 로고    scopus 로고
    • Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells
    • Cadet J., Douki T., Ravanat J.-L. Oxidatively generated damage to the guanine moiety of DNA: mechanistic aspects and formation in cells. Acc. Chem. Res. 2008, 41:1075-1083.
    • (2008) Acc. Chem. Res. , vol.41 , pp. 1075-1083
    • Cadet, J.1    Douki, T.2    Ravanat, J.-L.3
  • 29
    • 77951241977 scopus 로고    scopus 로고
    • Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions
    • Wagner J.R., Cadet J. Oxidation reactions of cytosine DNA components by hydroxyl radical and one-electron oxidants in aerated aqueous solutions. Acc. Chem. Res. 2010, 43:564-571.
    • (2010) Acc. Chem. Res. , vol.43 , pp. 564-571
    • Wagner, J.R.1    Cadet, J.2
  • 30
    • 38949209141 scopus 로고    scopus 로고
    • The chemical toxicology of 2-deoxyribose oxidation in DNA
    • Dedon P.C. The chemical toxicology of 2-deoxyribose oxidation in DNA. Chem. Res. Toxicol. 2008, 21:206-219.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 206-219
    • Dedon, P.C.1
  • 31
    • 79956190054 scopus 로고    scopus 로고
    • Measurement of oxidatively generated base damage in cellular DNA
    • Cadet J., Douki T., Ravanat J.-L. Measurement of oxidatively generated base damage in cellular DNA. Mutat. Res. 2011, 711:3-12.
    • (2011) Mutat. Res. , vol.711 , pp. 3-12
    • Cadet, J.1    Douki, T.2    Ravanat, J.-L.3
  • 33
  • 34
    • 78549249153 scopus 로고    scopus 로고
    • Mutagenicity of oxidized DNA precursors in living cells: roles of nucleotide pool sanitization and DNA repair enzymes, and translesion synthesis DNA polymerases
    • Kamiya H. Mutagenicity of oxidized DNA precursors in living cells: roles of nucleotide pool sanitization and DNA repair enzymes, and translesion synthesis DNA polymerases. Mutat. Res. 2010, 703:32-36.
    • (2010) Mutat. Res. , vol.703 , pp. 32-36
    • Kamiya, H.1
  • 36
    • 79957456954 scopus 로고    scopus 로고
    • Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage
    • Svilar D., Goellner E.M., Almeida K.H., Sobol R.W. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxid. Redox Signal. 2011, 14:2491-2497.
    • (2011) Antioxid. Redox Signal. , vol.14 , pp. 2491-2497
    • Svilar, D.1    Goellner, E.M.2    Almeida, K.H.3    Sobol, R.W.4
  • 37
    • 0034602643 scopus 로고    scopus 로고
    • Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation: oxidized bases and strand breaks
    • Sutherland B.M., Bennett P.V., Sidorkina O., Laval J. Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation: oxidized bases and strand breaks. Proc. Natl. Acad. Sci. USA 2000, 97:103-108.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 103-108
    • Sutherland, B.M.1    Bennett, P.V.2    Sidorkina, O.3    Laval, J.4
  • 38
    • 44349188585 scopus 로고    scopus 로고
    • Formation of clustered DNA damage after high-LET irradiation: a review
    • Hada M., Georgakilas A.G. Formation of clustered DNA damage after high-LET irradiation: a review. J. Radiat. Res. (Tokyo) 2008, 49:203-210.
    • (2008) J. Radiat. Res. (Tokyo) , vol.49 , pp. 203-210
    • Hada, M.1    Georgakilas, A.G.2
  • 39
    • 0027973491 scopus 로고
    • The complexity of DNA damage: relevance to biological consequences
    • Ward J.F. The complexity of DNA damage: relevance to biological consequences. Int. J. Radiat. Biol. 1994, 66:427-432.
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 427-432
    • Ward, J.F.1
  • 40
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation and repairability
    • Ward J.F. DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation and repairability. Prog. Nucleic Acids Mol. Biol. 1988, 35:95-125.
    • (1988) Prog. Nucleic Acids Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 41
    • 0027976408 scopus 로고
    • Initial events in the cellular effects of ionizing radiations: clustered damage in DNA
    • Goodhead D.T. Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. Int. J. Radiat. Biol. 1994, 65:7-17.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 7-17
    • Goodhead, D.T.1
  • 42
    • 60749131956 scopus 로고    scopus 로고
    • Radiation chemistry comes before radiation biology
    • O'Neill P., Wardman P. Radiation chemistry comes before radiation biology. Int. J. Radiat. Biol. 2009, 85:9-25.
    • (2009) Int. J. Radiat. Biol. , vol.85 , pp. 9-25
    • O'Neill, P.1    Wardman, P.2
  • 44
    • 0036129039 scopus 로고    scopus 로고
    • DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intermolecular addition of thymine peroxyl radical to guanine
    • Douki T., Rivière J., Cadet J. DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intermolecular addition of thymine peroxyl radical to guanine. Chem. Res. Toxicol. 2002, 15:445-454.
    • (2002) Chem. Res. Toxicol. , vol.15 , pp. 445-454
    • Douki, T.1    Rivière, J.2    Cadet, J.3
  • 45
    • 79956225907 scopus 로고    scopus 로고
    • Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis in cell survival
    • Sage E., Harrison L. Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis in cell survival. Mutat. Res. 2011, 711:123-133.
    • (2011) Mutat. Res. , vol.711 , pp. 123-133
    • Sage, E.1    Harrison, L.2
  • 47
    • 40149098121 scopus 로고    scopus 로고
    • DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts
    • Xu X., Muller J.G., Ye Y., Burrows C.J. DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts. J. Am. Chem. Soc. 2008, 130:703-709.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 703-709
    • Xu, X.1    Muller, J.G.2    Ye, Y.3    Burrows, C.J.4
  • 48
    • 84858115501 scopus 로고    scopus 로고
    • Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids
    • Cadet J., Loft S., Olinski R., Evans M.D., Bialkowski K., Wagner J.R., Dedon P.C., Moeller P., Greenberg M.M., Cooke M.S. Biologically relevant oxidants and terminology, classification and nomenclature of oxidatively generated damage to nucleobases and 2-deoxyribose in nucleic acids. Free Radic. Res. 2012, 48:367-381.
    • (2012) Free Radic. Res. , vol.48 , pp. 367-381
    • Cadet, J.1    Loft, S.2    Olinski, R.3    Evans, M.D.4    Bialkowski, K.5    Wagner, J.R.6    Dedon, P.C.7    Moeller, P.8    Greenberg, M.M.9    Cooke, M.S.10
  • 50
    • 84855340007 scopus 로고    scopus 로고
    • Multiple forms of DNA damage caused by UVA photoactivation of DNA 6-thioguanine
    • Brem R., Karran P. Multiple forms of DNA damage caused by UVA photoactivation of DNA 6-thioguanine. Photochem. Photobiol. 2012, 88:5-13.
    • (2012) Photochem. Photobiol. , vol.88 , pp. 5-13
    • Brem, R.1    Karran, P.2
  • 51
    • 34248577756 scopus 로고    scopus 로고
    • The carbonate radical and related oxidants derived from bicarbonate buffer
    • Medinas D.B., Cerchiaro G., Trindade D.F., Augusto O. The carbonate radical and related oxidants derived from bicarbonate buffer. IUBMB Life 2007, 59:255-262.
    • (2007) IUBMB Life , vol.59 , pp. 255-262
    • Medinas, D.B.1    Cerchiaro, G.2    Trindade, D.F.3    Augusto, O.4
  • 52
    • 0035816604 scopus 로고    scopus 로고
    • The carbonate radical is a site-selective oxidizing agent of guanine in double-stranded oligonucleotides
    • Shafirovich V., Dourandin A., Huang W., Geacintov N.E. The carbonate radical is a site-selective oxidizing agent of guanine in double-stranded oligonucleotides. J. Biol. Chem. 2001, 276:24621-24626.
    • (2001) J. Biol. Chem. , vol.276 , pp. 24621-24626
    • Shafirovich, V.1    Dourandin, A.2    Huang, W.3    Geacintov, N.E.4
  • 53
    • 0029868695 scopus 로고    scopus 로고
    • Radiation-induced formation of a crosslink between base moiety of deoxyguanosine and thymidine in deoxygenated solutions of d(CpGpTpA)
    • Box H.C., Budzinski E.E., Dawidzik J.B., Wallace J.C., Evans M.S., Gobey J.S. Radiation-induced formation of a crosslink between base moiety of deoxyguanosine and thymidine in deoxygenated solutions of d(CpGpTpA). Radiat. Res. 1996, 145:641-643.
    • (1996) Radiat. Res. , vol.145 , pp. 641-643
    • Box, H.C.1    Budzinski, E.E.2    Dawidzik, J.B.3    Wallace, J.C.4    Evans, M.S.5    Gobey, J.S.6
  • 54
    • 0036229483 scopus 로고    scopus 로고
    • Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurements in gamma-irradiated isolated DNA
    • Bellon S., Ravanat J.-L., Gasparutto D., Cadet J. Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurements in gamma-irradiated isolated DNA. Chem. Res. Toxicol. 2002, 15:598-606.
    • (2002) Chem. Res. Toxicol. , vol.15 , pp. 598-606
    • Bellon, S.1    Ravanat, J.-L.2    Gasparutto, D.3    Cadet, J.4
  • 55
    • 35948976591 scopus 로고    scopus 로고
    • In vivo formation and in vitro replication of a guanine-thymine intrastrand cross-link lesion
    • Jiang Y., Hong H., Cao H., Wang Y. In vivo formation and in vitro replication of a guanine-thymine intrastrand cross-link lesion. Biochemistry 2007, 46:12757-12763.
    • (2007) Biochemistry , vol.46 , pp. 12757-12763
    • Jiang, Y.1    Hong, H.2    Cao, H.3    Wang, Y.4
  • 56
    • 37549068564 scopus 로고    scopus 로고
    • Formation and genotoxicity of a guanine-cytosine intrastrand cross-link lesion in vivo
    • Hong H., Cao H., Wang Y. Formation and genotoxicity of a guanine-cytosine intrastrand cross-link lesion in vivo. Nucleic Acids Res. 2007, 35:7118-7127.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7118-7127
    • Hong, H.1    Cao, H.2    Wang, Y.3
  • 57
    • 41649091432 scopus 로고    scopus 로고
    • Bulky DNA lesions induced by reactive oxygen species
    • Wang Y. Bulky DNA lesions induced by reactive oxygen species. Chem. Res. Toxicol. 2008, 21:276-281.
    • (2008) Chem. Res. Toxicol. , vol.21 , pp. 276-281
    • Wang, Y.1
  • 58
    • 33749568819 scopus 로고    scopus 로고
    • Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication
    • Bellon S., Gasparutto D., Saint-Pierre C., Cadet J. Guanine-thymine intrastrand cross-linked lesion containing oligonucleotides: from chemical synthesis to in vitro enzymatic replication. Org. Biomol. Chem. 2006, 4:3831-3837.
    • (2006) Org. Biomol. Chem. , vol.4 , pp. 3831-3837
    • Bellon, S.1    Gasparutto, D.2    Saint-Pierre, C.3    Cadet, J.4
  • 59
    • 2542624579 scopus 로고    scopus 로고
    • LC-MS/MS identification and yeast polymerase η bypass of a novel γ-irradiation-induced intrastrand cross-link lesion G[8-5]C
    • Gu C., Wang Y. LC-MS/MS identification and yeast polymerase η bypass of a novel γ-irradiation-induced intrastrand cross-link lesion G[8-5]C. Biochemistry 2004, 43:6745-6750.
    • (2004) Biochemistry , vol.43 , pp. 6745-6750
    • Gu, C.1    Wang, Y.2
  • 60
    • 20544472885 scopus 로고    scopus 로고
    • Thermodynamic and in-vitro replication studies of an intrastrand crosslink lesion G[8-5]C
    • Gu C., Wang Y. Thermodynamic and in-vitro replication studies of an intrastrand crosslink lesion G[8-5]C. Biochemistry 2005, 44:8883-8889.
    • (2005) Biochemistry , vol.44 , pp. 8883-8889
    • Gu, C.1    Wang, Y.2
  • 61
    • 79952950966 scopus 로고    scopus 로고
    • Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass
    • Raychaudhury P., Basu A.K. Genetic requirement for mutagenesis of the G[8,5-Me]T cross-link in Escherichia coli: DNA polymerases IV and V compete for error-prone bypass. Biochemistry 2011, 50:2330-2338.
    • (2011) Biochemistry , vol.50 , pp. 2330-2338
    • Raychaudhury, P.1    Basu, A.K.2
  • 62
    • 48649092842 scopus 로고    scopus 로고
    • Mutational specificity of γ-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase η
    • Colis L.C., Raychaudhury P., Basu A.K. Mutational specificity of γ-radiation-induced guanine-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase η. Biochemistry 2008, 47:8070-8079.
    • (2008) Biochemistry , vol.47 , pp. 8070-8079
    • Colis, L.C.1    Raychaudhury, P.2    Basu, A.K.3
  • 63
    • 84855634612 scopus 로고    scopus 로고
    • Replication past the γ-radiation-induced guanine-thymine cross-link G[8-5]T by human and yeast DNA polymerase η
    • (No. 101495)
    • Raychaudhury P., Basu A.K. Replication past the γ-radiation-induced guanine-thymine cross-link G[8-5]T by human and yeast DNA polymerase η. J. Nucleic Acids 2010, (No. 101495).
    • (2010) J. Nucleic Acids
    • Raychaudhury, P.1    Basu, A.K.2
  • 64
    • 25444460601 scopus 로고    scopus 로고
    • Recognition and insertion of γ-radiation-induced cross-linked guanine-thymine tandem lesion G[8-5Me]T by UvrABC nuclease
    • Yang Z., Colis L.C., Basu A.K., Zou Y. Recognition and insertion of γ-radiation-induced cross-linked guanine-thymine tandem lesion G[8-5Me]T by UvrABC nuclease. Chem. Res. Toxicol. 2005, 18:1339-1346.
    • (2005) Chem. Res. Toxicol. , vol.18 , pp. 1339-1346
    • Yang, Z.1    Colis, L.C.2    Basu, A.K.3    Zou, Y.4
  • 65
    • 33748258358 scopus 로고    scopus 로고
    • Recognition and incision of oxidative intrastrand cross-link lesions by UvrABC nuclease
    • Gu C., Zhang Q., Yang Z., Wang Y., Zou Y., Wang Y. Recognition and incision of oxidative intrastrand cross-link lesions by UvrABC nuclease. Biochemistry 2006, 45:10739-10746.
    • (2006) Biochemistry , vol.45 , pp. 10739-10746
    • Gu, C.1    Zhang, Q.2    Yang, Z.3    Wang, Y.4    Zou, Y.5    Wang, Y.6
  • 68
    • 84866002687 scopus 로고    scopus 로고
    • Oxidatively generated nucleobase modifications in isolated and cellular DNA
    • John Wiley & Sons, Chichester, UK, C. Chatgilialoglu, A. Studer (Eds.)
    • Cadet J., Douki T., Gasparutto D., Ravanat J.-L., Wagner J.R. Oxidatively generated nucleobase modifications in isolated and cellular DNA. Encyclopedia of Radicals in Chemistry, Biology and Materials 2012, 1319-1344. John Wiley & Sons, Chichester, UK. C. Chatgilialoglu, A. Studer (Eds.).
    • (2012) Encyclopedia of Radicals in Chemistry, Biology and Materials , pp. 1319-1344
    • Cadet, J.1    Douki, T.2    Gasparutto, D.3    Ravanat, J.-L.4    Wagner, J.R.5
  • 69
    • 0034678995 scopus 로고    scopus 로고
    • Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution
    • Bourdat A.G., Douki T., Frelon S., Gasparutto D., Cadet J. Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution. J. Am. Chem. Soc. 2000, 122:4549-4556.
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 4549-4556
    • Bourdat, A.G.1    Douki, T.2    Frelon, S.3    Gasparutto, D.4    Cadet, J.5
  • 70
    • 77950479122 scopus 로고    scopus 로고
    • radicals induced an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases
    • radicals induced an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases. Proc. Natl. Acad. Sci. USA 2010, 107:5528-5533.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 5528-5533
    • Bergeron, F.1    Auvré, F.2    Radicella, J.P.3    Ravanat, J.-L.4
  • 71
    • 34247153489 scopus 로고    scopus 로고
    • Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical
    • Hong S., Carter K.N., Sato K., Greenberg M.M. Characterization and mechanism of formation of tandem lesions in DNA by a nucleobase peroxyl radical. J. Am. Chem. Soc. 2007, 129:4089-4098.
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 4089-4098
    • Hong, S.1    Carter, K.N.2    Sato, K.3    Greenberg, M.M.4
  • 72
    • 43249107944 scopus 로고    scopus 로고
    • Selective one-electron oxidation of duplex DNA oligomers: reactions at thymine
    • Ghosh A., Joy A., Schuster G.B., Douki T., Cadet J. Selective one-electron oxidation of duplex DNA oligomers: reactions at thymine. Org. Biomol. Chem. 2008, 6:916-928.
    • (2008) Org. Biomol. Chem. , vol.6 , pp. 916-928
    • Ghosh, A.1    Joy, A.2    Schuster, G.B.3    Douki, T.4    Cadet, J.5
  • 73
    • 69049115319 scopus 로고    scopus 로고
    • The mutagenicity of thymidine glycol in E. coli is increased when part of a tandem lesion
    • Huang H., Imoto S., Greenberg M.M. The mutagenicity of thymidine glycol in E. coli is increased when part of a tandem lesion. Biochemistry 2009, 48:7833-7841.
    • (2009) Biochemistry , vol.48 , pp. 7833-7841
    • Huang, H.1    Imoto, S.2    Greenberg, M.M.3
  • 74
    • 0034691679 scopus 로고    scopus 로고
    • Mutation spectra induced by replication of two vicinal oxidative DNA lesions in mammalian cells
    • Gentil A., Le Page F., Cadet J., Sarasin A. Mutation spectra induced by replication of two vicinal oxidative DNA lesions in mammalian cells. Mutat. Res. 2000, 452:51-56.
    • (2000) Mutat. Res. , vol.452 , pp. 51-56
    • Gentil, A.1    Le Page, F.2    Cadet, J.3    Sarasin, A.4
  • 75
    • 65949088796 scopus 로고    scopus 로고
    • In-vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine
    • Jiang Y., Wang Y., Wang Y. In-vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine. Chem. Res. Toxicol. 2009, 22:574-583.
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 574-583
    • Jiang, Y.1    Wang, Y.2    Wang, Y.3
  • 76
    • 75149112818 scopus 로고    scopus 로고
    • Efficient formation of tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells
    • Yuan B., Jian Y., Wang Y., Wang Y. Efficient formation of tandem thymine glycol/8-oxo-7,8-dihydroguanine lesion in isolated DNA and the mutagenic and cytotoxic properties of the tandem lesions in Escherichia coli cells. Chem. Res. Toxicol. 2010, 23:11-19.
    • (2010) Chem. Res. Toxicol. , vol.23 , pp. 11-19
    • Yuan, B.1    Jian, Y.2    Wang, Y.3    Wang, Y.4
  • 77
    • 0033557286 scopus 로고    scopus 로고
    • Synthesis and enzymatic processing of oligodeoxynucleotides containing tandem base damage
    • Bourdat A.-G., Gasparutto D., Cadet J. Synthesis and enzymatic processing of oligodeoxynucleotides containing tandem base damage. Nucleic Acids Res. 1999, 27:1015-1024.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 1015-1024
    • Bourdat, A.-G.1    Gasparutto, D.2    Cadet, J.3
  • 78
    • 39449125320 scopus 로고    scopus 로고
    • Oxidation of single-stranded oligonucleotides by carbonate anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines
    • Crean C., Uvaydov Y., Geacintov N.E., Shafirovich V. Oxidation of single-stranded oligonucleotides by carbonate anions: generating intrastrand cross-links between guanine and thymine bases separated by cytosines. Nucleic Acids Res. 2008, 36:742-755.
    • (2008) Nucleic Acids Res. , vol.36 , pp. 742-755
    • Crean, C.1    Uvaydov, Y.2    Geacintov, N.E.3    Shafirovich, V.4
  • 79
    • 79960506637 scopus 로고    scopus 로고
    • Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide
    • Yun B.H., Geacintov N.E., Shafirovich V. Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide. Chem. Res. Toxicol. 2011, 24:1144-1152.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 1144-1152
    • Yun, B.H.1    Geacintov, N.E.2    Shafirovich, V.3
  • 80
    • 84859351318 scopus 로고    scopus 로고
    • Structural, energetic and dynamic properties of guanine (C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair
    • Ding S., Kropachev K., Cai Y., Kolbanovskiy M., Durandina S.A., Liu Z., Shafirovich V., Broyde S., Geacintov N.E. Structural, energetic and dynamic properties of guanine (C8)-thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair. Nucleic Acids Res. 2012, 40:2506-2517.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 2506-2517
    • Ding, S.1    Kropachev, K.2    Cai, Y.3    Kolbanovskiy, M.4    Durandina, S.A.5    Liu, Z.6    Shafirovich, V.7    Broyde, S.8    Geacintov, N.E.9
  • 81
    • 79951940120 scopus 로고    scopus 로고
    • Purine 5',8-cyclonucleoside lesions: chemistry and biology
    • Chatgilialoglu C., Ferreri C C., Terzidis M.A. Purine 5',8-cyclonucleoside lesions: chemistry and biology. Chem. Soc. Rev. 2011, 40:1368-1382.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 1368-1382
    • Chatgilialoglu, C.1    Ferreri C, C.2    Terzidis, M.A.3
  • 82
    • 0034636004 scopus 로고    scopus 로고
    • Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision repair pathway in human cells
    • Kuruoka I., Bender C., Romieu A., Cadet J., Wood R.D., Lindhal T. Removal of oxygen free-radical-induced 5',8-purine cyclodeoxynucleosides from DNA by the nucleotide excision repair pathway in human cells. Proc. Natl. Acad. Sci. USA 2000, 97:3832-3837.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3832-3837
    • Kuruoka, I.1    Bender, C.2    Romieu, A.3    Cadet, J.4    Wood, R.D.5    Lindhal, T.6
  • 83
    • 34247148895 scopus 로고    scopus 로고
    • The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum
    • Brooks P.J. The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum. Neuroscience 2007, 145:1407-1417.
    • (2007) Neuroscience , vol.145 , pp. 1407-1417
    • Brooks, P.J.1
  • 84
    • 44949263779 scopus 로고    scopus 로고
    • The 8,5'-cyclopurine-2'-deoxynucleosides: Candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair
    • Brooks P.J. The 8,5'-cyclopurine-2'-deoxynucleosides: Candidate neurodegenerative DNA lesions in xeroderma pigmentosum, and unique probes of transcription and nucleotide excision repair. DNA Repair (Amsterdam) 2008, 7:1168-1179.
    • (2008) DNA Repair (Amsterdam) , vol.7 , pp. 1168-1179
    • Brooks, P.J.1
  • 85
    • 77954580095 scopus 로고    scopus 로고
    • Radiation-induced formation of purine 5',8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen
    • Belmadoui N., Boussicault F., Guerra M., Ravanat J.-L., Chatgilialoglu C., Cadet J. Radiation-induced formation of purine 5',8-cyclonucleosides in isolated and cellular DNA: high stereospecificity and modulating effect of oxygen. Org. Biomol. Chem. 2010, 8:3211-3219.
    • (2010) Org. Biomol. Chem. , vol.8 , pp. 3211-3219
    • Belmadoui, N.1    Boussicault, F.2    Guerra, M.3    Ravanat, J.-L.4    Chatgilialoglu, C.5    Cadet, J.6
  • 87
    • 84055213102 scopus 로고    scopus 로고
    • New insights into the reaction paths of hydroxyl radicals with 2'-deoxyguanosine
    • Chatgilialoglu C., D'Angelantonio M., Kciuk G., Bobrowski K. New insights into the reaction paths of hydroxyl radicals with 2'-deoxyguanosine. Chem. Res. Toxicol. 2011, 24:2200-2206.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 2200-2206
    • Chatgilialoglu, C.1    D'Angelantonio, M.2    Kciuk, G.3    Bobrowski, K.4
  • 88
    • 29344473246 scopus 로고    scopus 로고
    • Theoretical study of the tandem cross-linkage lesion in DNA
    • Zhang R.b., Eriksson L.A. Theoretical study of the tandem cross-linkage lesion in DNA. Chem. Phys. Lett. 2006, 417:303-308.
    • (2006) Chem. Phys. Lett. , vol.417 , pp. 303-308
    • Zhang, R.1    Eriksson, L.A.2
  • 91
    • 79954589295 scopus 로고    scopus 로고
    • Quantification of oxidative DNA lesions in tissues of Long-Evans cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method
    • Wang J., Yuan B., Guerrero C., Bahde R., Gupta S., Wang Y. Quantification of oxidative DNA lesions in tissues of Long-Evans cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method. Anal. Chem. 2011, 83:2201-2209.
    • (2011) Anal. Chem. , vol.83 , pp. 2201-2209
    • Wang, J.1    Yuan, B.2    Guerrero, C.3    Bahde, R.4    Gupta, S.5    Wang, Y.6
  • 92
    • 0033969864 scopus 로고    scopus 로고
    • Repair and replication of oxidized DNA bases using modified oligodeoxyribonucleotides
    • Gasparutto D., Bourdat A.G., D'Ham C., Duarte V., Romieu A., Cadet J. Repair and replication of oxidized DNA bases using modified oligodeoxyribonucleotides. Biochimie 2000, 82:19-24.
    • (2000) Biochimie , vol.82 , pp. 19-24
    • Gasparutto, D.1    Bourdat, A.G.2    D'Ham, C.3    Duarte, V.4    Romieu, A.5    Cadet, J.6
  • 94
    • 0035966003 scopus 로고    scopus 로고
    • Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase η and resistance to exonucleases action at cyclopurine deoxynucleoside residues
    • Kuraoka I., Robins P., Masutani C., Hanaoka F., Gasparutto D., Cadet J., Wood R.D., Lindahl T. Oxygen free radical damage to DNA. Translesion synthesis by human DNA polymerase η and resistance to exonucleases action at cyclopurine deoxynucleoside residues. J. Biol. Chem. 2001, 276:49283-49288.
    • (2001) J. Biol. Chem. , vol.276 , pp. 49283-49288
    • Kuraoka, I.1    Robins, P.2    Masutani, C.3    Hanaoka, F.4    Gasparutto, D.5    Cadet, J.6    Wood, R.D.7    Lindahl, T.8
  • 95
    • 0000964269 scopus 로고    scopus 로고
    • Site-specific introduction of (5'S)-5',8-cyclo-2'-deoxyadenosine into oligodeoxynucleotides
    • Romieu A., Gasparutto D., Molko D., Cadet J. Site-specific introduction of (5'S)-5',8-cyclo-2'-deoxyadenosine into oligodeoxynucleotides. J. Org. Chem. 1998, 63:5245-5249.
    • (1998) J. Org. Chem. , vol.63 , pp. 5245-5249
    • Romieu, A.1    Gasparutto, D.2    Molko, D.3    Cadet, J.4
  • 96
    • 0032782017 scopus 로고    scopus 로고
    • Synthesis and characterization of oligonucleotides containing 5',8-cyclopurine 2'-deoxyribonucleosides : (5'R)-5',8-cyclo-2'-deoxyadenosine, (5'S)-5',8-cyclo-2'-deoxyguanosine, and (5'R)-5',8-cyclo-2thomampersa
    • Romieu A., Gasparutto D., Cadet J. Synthesis and characterization of oligonucleotides containing 5',8-cyclopurine 2'-deoxyribonucleosides : (5'R)-5',8-cyclo-2'-deoxyadenosine, (5'S)-5',8-cyclo-2'-deoxyguanosine, and (5'R)-5',8-cyclo-2'-deoxyguanosine. Chem. Res. Toxicol. 1999, 12:412-421.
    • (1999) Chem. Res. Toxicol. , vol.12 , pp. 412-421
    • Romieu, A.1    Gasparutto, D.2    Cadet, J.3
  • 97
    • 76749136353 scopus 로고    scopus 로고
    • Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosine
    • Jaruga P., Xiao Y., Vartanian V., Lloyd R.S., Dizdaroglu M. Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-cyclo-2'-deoxyadenosine. Biochemistry 2010, 49:1053-1055.
    • (2010) Biochemistry , vol.49 , pp. 1053-1055
    • Jaruga, P.1    Xiao, Y.2    Vartanian, V.3    Lloyd, R.S.4    Dizdaroglu, M.5
  • 98
    • 79955832048 scopus 로고    scopus 로고
    • (5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and it inefficiently repaired in Escherichia coli
    • Jasti V.P., Das R.S., Hilton B.A., Weerasooriya S., Zou Y., Basu A.K. (5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and it inefficiently repaired in Escherichia coli. Biochemistry 2011, 50:3862-3865.
    • (2011) Biochemistry , vol.50 , pp. 3862-3865
    • Jasti, V.P.1    Das, R.S.2    Hilton, B.A.3    Weerasooriya, S.4    Zou, Y.5    Basu, A.K.6
  • 99
    • 83755168927 scopus 로고    scopus 로고
    • Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA
    • Huang H., Das R.S., Basu A.K., Stone M.P. Structure of (5'S)-8,5'-cyclo-2'-deoxyguanosine in DNA. J. Am. Chem. Soc. 2011, 133:20357-20368.
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 20357-20368
    • Huang, H.1    Das, R.S.2    Basu, A.K.3    Stone, M.P.4
  • 100
    • 79959352056 scopus 로고    scopus 로고
    • High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing
    • Yuan B., Wang J., Cao H., Sun R., Wang Y. High-throughput analysis of the mutagenic and cytotoxic properties of DNA lesions by next-generation sequencing. Nucleic Acids Res. 2011, 39:5945-5954.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5945-5954
    • Yuan, B.1    Wang, J.2    Cao, H.3    Sun, R.4    Wang, Y.5
  • 101
    • 33745198667 scopus 로고    scopus 로고
    • Assay for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo
    • Delaney J.C., Essigmann J.M. Assay for determining lesion bypass efficiency and mutagenicity of site-specific DNA lesions in vivo. Methods Enzymol. 2006, 408:1-15.
    • (2006) Methods Enzymol. , vol.408 , pp. 1-15
    • Delaney, J.C.1    Essigmann, J.M.2
  • 102
    • 54949139647 scopus 로고    scopus 로고
    • Inducible SOS response system of DNA repair and mutagenesis in Escherichia coli
    • Janion C. Inducible SOS response system of DNA repair and mutagenesis in Escherichia coli. Int. J. Biol. Sci. 2008, 338-344.
    • (2008) Int. J. Biol. Sci. , pp. 338-344
    • Janion, C.1
  • 103
    • 34047096423 scopus 로고    scopus 로고
    • Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cells
    • Marietta C., Brooks P.J. Transcriptional bypass of bulky DNA lesions causes new mutant RNA transcripts in human cells. EMBO Rep. 2007, 8:388-393.
    • (2007) EMBO Rep. , vol.8 , pp. 388-393
    • Marietta, C.1    Brooks, P.J.2
  • 104
    • 0036837134 scopus 로고    scopus 로고
    • A single 8,5'-cyclo-2'-deoxyadenosine lesion in a TATA box prevents binding of the TATA binding protein and strongly reduces transcription in vivo
    • Marietta C., Gulam H., Brooks P.J. A single 8,5'-cyclo-2'-deoxyadenosine lesion in a TATA box prevents binding of the TATA binding protein and strongly reduces transcription in vivo. DNA Repair (Amsterdam) 2002, 1:967-975.
    • (2002) DNA Repair (Amsterdam) , vol.1 , pp. 967-975
    • Marietta, C.1    Gulam, H.2    Brooks, P.J.3
  • 105
    • 79953694175 scopus 로고    scopus 로고
    • Divergent effects of oxidatively induced modification to the C8 of 2'-deoxyadenosine on transcription factor binding: 8;5'(S)-cyclo-2'-deoxyadenosine inhibits the binding of multiple sequence specific transcription factors, while 8-oxo-2'-deoxyadenosine increases binding of CREB and NF-kappa B to DNA
    • Abraham J., Brooks P.J. Divergent effects of oxidatively induced modification to the C8 of 2'-deoxyadenosine on transcription factor binding: 8;5'(S)-cyclo-2'-deoxyadenosine inhibits the binding of multiple sequence specific transcription factors, while 8-oxo-2'-deoxyadenosine increases binding of CREB and NF-kappa B to DNA. Environ. Mol. Mutagen. 2011, 52:287-295.
    • (2011) Environ. Mol. Mutagen. , vol.52 , pp. 287-295
    • Abraham, J.1    Brooks, P.J.2
  • 108
    • 15944429355 scopus 로고    scopus 로고
    • DNA-protein crosslinks: their induction, repair, and biological consequences
    • Barker S., Weinfeld M., Murray D. DNA-protein crosslinks: their induction, repair, and biological consequences. Mutat. Res. 2005, 580:111-135.
    • (2005) Mutat. Res. , vol.580 , pp. 111-135
    • Barker, S.1    Weinfeld, M.2    Murray, D.3
  • 109
    • 26644437215 scopus 로고    scopus 로고
    • Identification of mammalian proteins cross-linked to DNA by ionizing radiation
    • Barker S., Weinfeld M., Zheng J., Li L., Murray D. Identification of mammalian proteins cross-linked to DNA by ionizing radiation. J. Biol. Chem. 2005, 280:33826-33838.
    • (2005) J. Biol. Chem. , vol.280 , pp. 33826-33838
    • Barker, S.1    Weinfeld, M.2    Zheng, J.3    Li, L.4    Murray, D.5
  • 110
    • 23944471409 scopus 로고    scopus 로고
    • A method for the isolation of covalent DNA-protein crosslinks suitable for proteomics analysis
    • Barker S., Murray D., Zheng J., Li L., Weinfeld M. A method for the isolation of covalent DNA-protein crosslinks suitable for proteomics analysis. Anal. Biochem. 2005, 344:204-215.
    • (2005) Anal. Biochem. , vol.344 , pp. 204-215
    • Barker, S.1    Murray, D.2    Zheng, J.3    Li, L.4    Weinfeld, M.5
  • 112
    • 0024399817 scopus 로고
    • Structure and mechanism of hydroxyl radical-induced formation of a DNA- protein cross-link involving thymine and lysine in nucleohistone
    • Dizdaroglu M., Gajewski E. Structure and mechanism of hydroxyl radical-induced formation of a DNA- protein cross-link involving thymine and lysine in nucleohistone. Cancer Res. 1989, 49:3463-3467.
    • (1989) Cancer Res. , vol.49 , pp. 3463-3467
    • Dizdaroglu, M.1    Gajewski, E.2
  • 113
    • 84858133452 scopus 로고    scopus 로고
    • Mechanisms of free radical-induced damage to DNA
    • Dizdaroglu M., Jaruga P. Mechanisms of free radical-induced damage to DNA. Free Radic. Res. 2012, 46:382-419.
    • (2012) Free Radic. Res. , vol.46 , pp. 382-419
    • Dizdaroglu, M.1    Jaruga, P.2
  • 114
    • 84877627020 scopus 로고
    • Photosensitized formation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-hydroxy-2'-deoxyguanosine) in DNA by riboflavin: a non-singlet oxygen mediated reaction
    • Kasai H., Yamaizumi Z., Berger M., Cadet J. Photosensitized formation of 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-hydroxy-2'-deoxyguanosine) in DNA by riboflavin: a non-singlet oxygen mediated reaction. J. Am. Chem. Soc. 1992, 114:9692-9694.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 9692-9694
    • Kasai, H.1    Yamaizumi, Z.2    Berger, M.3    Cadet, J.4
  • 115
    • 33646583190 scopus 로고    scopus 로고
    • Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide
    • Perrier S., Hau J., Gasparutto D., Cadet J., Favier A., Ravanat J.-L. Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide. J. Am. Chem. Soc. 2006, 128:5703-5710.
    • (2006) J. Am. Chem. Soc. , vol.128 , pp. 5703-5710
    • Perrier, S.1    Hau, J.2    Gasparutto, D.3    Cadet, J.4    Favier, A.5    Ravanat, J.-L.6
  • 117
    • 84856932343 scopus 로고    scopus 로고
    • Dependence of DNA-protein cross-linking via guanine oxidation upon local DNA sequence as studied by restriction endonuclease inhibition
    • Madison A.L., Perez Z.A., To P., Maisonet T., Rios E.V., Trejo Y., Ochoa-Paniagua C., Reno A., Stemp E.D.A. Dependence of DNA-protein cross-linking via guanine oxidation upon local DNA sequence as studied by restriction endonuclease inhibition. Biochemistry 2012, 51:362-369.
    • (2012) Biochemistry , vol.51 , pp. 362-369
    • Madison, A.L.1    Perez, Z.A.2    To, P.3    Maisonet, T.4    Rios, E.V.5    Trejo, Y.6    Ochoa-Paniagua, C.7    Reno, A.8    Stemp, E.D.A.9
  • 119
    • 0344034180 scopus 로고    scopus 로고
    • Solution study of the NF-kappa B p50-DNA complex by UV laser protein-DNA cross-linking
    • Angelov D., Charra M., Müller C.W., Cadet J., Dimitrov S. Solution study of the NF-kappa B p50-DNA complex by UV laser protein-DNA cross-linking. Photochem. Photobiol. 2003, 77:592-596.
    • (2003) Photochem. Photobiol. , vol.77 , pp. 592-596
    • Angelov, D.1    Charra, M.2    Müller, C.W.3    Cadet, J.4    Dimitrov, S.5
  • 122
    • 79960270911 scopus 로고    scopus 로고
    • Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
    • Gueranger Q., Kia A., Frith D., Karran P. Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA. Nucleic Acids Res. 2011, 39:5057-5060.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5057-5060
    • Gueranger, Q.1    Kia, A.2    Frith, D.3    Karran, P.4
  • 124
    • 33746606573 scopus 로고    scopus 로고
    • Repair of DNA-protein cross-links in mammalian cells
    • Reardon J.T., Cheng Y., Sancar A. Repair of DNA-protein cross-links in mammalian cells. Cell Cycle 2006, 5:1366-1370.
    • (2006) Cell Cycle , vol.5 , pp. 1366-1370
    • Reardon, J.T.1    Cheng, Y.2    Sancar, A.3
  • 125
    • 0034830066 scopus 로고    scopus 로고
    • The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III
    • Hashimoto M., Greenberg M.M., Kow Y.W., Hwang J.T., Cunningham R.P. The 2-deoxyribonolactone lesion produced in DNA by neocarzinostatin and other damaging agents forms cross-links with the base-excision repair enzyme endonuclease III. J. Am. Chem. Soc. 2001, 123:3161-3162.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 3161-3162
    • Hashimoto, M.1    Greenberg, M.M.2    Kow, Y.W.3    Hwang, J.T.4    Cunningham, R.P.5
  • 127
    • 33745214433 scopus 로고    scopus 로고
    • Analysis of base excision DNA repair of the oxidative lesion 2-deoxyribonolactone and the formation of DNA-protein cross-links
    • Sung J.S., Demple B. Analysis of base excision DNA repair of the oxidative lesion 2-deoxyribonolactone and the formation of DNA-protein cross-links. Methods Enzymol. 2006, 408:48-64.
    • (2006) Methods Enzymol. , vol.408 , pp. 48-64
    • Sung, J.S.1    Demple, B.2
  • 129
    • 78651077907 scopus 로고    scopus 로고
    • Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle
    • Sczepanski J.T., Wong R.S., McKnight J.N., Bowman G.D., Greenberg M.M. Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle. Proc. Natl. Acad. Sci. USA 2010, 107:22475-22480.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 22475-22480
    • Sczepanski, J.T.1    Wong, R.S.2    McKnight, J.N.3    Bowman, G.D.4    Greenberg, M.M.5
  • 130
    • 34250900982 scopus 로고    scopus 로고
    • Base-excision repair of oxidative DNA damage
    • David S.S., O'Shea V.L., Kundu S. Base-excision repair of oxidative DNA damage. Nature 2007, 447:941-950.
    • (2007) Nature , vol.447 , pp. 941-950
    • David, S.S.1    O'Shea, V.L.2    Kundu, S.3
  • 131
    • 77951977767 scopus 로고    scopus 로고
    • DNA interstrand cross-links induced by ionizing radiation: an unsung lesion
    • Dextraze M.E., Gantchev T., Girouard S., Hunting D. DNA interstrand cross-links induced by ionizing radiation: an unsung lesion. Mutat. Res. 2010, 704:101-107.
    • (2010) Mutat. Res. , vol.704 , pp. 101-107
    • Dextraze, M.E.1    Gantchev, T.2    Girouard, S.3    Hunting, D.4
  • 132
    • 79960250117 scopus 로고    scopus 로고
    • Guanine radical chemistry reveals the effect of thermal fluctuations in gene promoter regions
    • Cuesta-López S., Menoni H., Angelov D., Peyrard M. Guanine radical chemistry reveals the effect of thermal fluctuations in gene promoter regions. Nucleic Acids Res. 2011, 39:5276-5283.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5276-5283
    • Cuesta-López, S.1    Menoni, H.2    Angelov, D.3    Peyrard, M.4
  • 133
    • 84255176347 scopus 로고    scopus 로고
    • UVA photosensitization of thiopurines and skin cancer in organ transplant recipients
    • Attard N.R., Karran P. UVA photosensitization of thiopurines and skin cancer in organ transplant recipients. Photochem. Photobiol. Sci. 2011, 11:62-68.
    • (2011) Photochem. Photobiol. Sci. , vol.11 , pp. 62-68
    • Attard, N.R.1    Karran, P.2
  • 134
    • 79960696914 scopus 로고    scopus 로고
    • P. Karran., Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation
    • Brem R., Daehn I. P. Karran., Efficient DNA interstrand crosslinking by 6-thioguanine and UVA radiation. DNA Repair (Amsterdam) 2011, 10:869-876.
    • (2011) DNA Repair (Amsterdam) , vol.10 , pp. 869-876
    • Brem, R.1    Daehn, I.2
  • 135
    • 4644309175 scopus 로고    scopus 로고
    • Detection of new radiation-induced DNA lesions by liquid chromatography coupled to tandem mass spectrometry
    • Regulus P., Spessotto S., Gateau M., Cadet J., Favier A., Ravanat J.-L. Detection of new radiation-induced DNA lesions by liquid chromatography coupled to tandem mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18:2223-2228.
    • (2004) Rapid Commun. Mass Spectrom. , vol.18 , pp. 2223-2228
    • Regulus, P.1    Spessotto, S.2    Gateau, M.3    Cadet, J.4    Favier, A.5    Ravanat, J.-L.6
  • 136
    • 35348826722 scopus 로고    scopus 로고
    • Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion
    • Regulus P., Duroux B., Bayle P.A., Favier A., Cadet J., Ravanat J.-L. Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion. Proc. Natl. Acad. Sci. USA 2006, 104:14032-14037.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14032-14037
    • Regulus, P.1    Duroux, B.2    Bayle, P.A.3    Favier, A.4    Cadet, J.5    Ravanat, J.-L.6
  • 137
    • 48249140226 scopus 로고    scopus 로고
    • Self-promoted DNA interstrand cross-link formation by an abasic site
    • Sczepanski J.T., Jacobs A.C., Greenberg M.M. Self-promoted DNA interstrand cross-link formation by an abasic site. J. Am. Chem. Soc. 2008, 130:9646-9647.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 9646-9647
    • Sczepanski, J.T.1    Jacobs, A.C.2    Greenberg, M.M.3
  • 138
    • 68249133580 scopus 로고    scopus 로고
    • Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site
    • Sczepanski J.T., Jacobs A.C., Majumdar A., Greenberg M.M. Scope and mechanism of interstrand cross-link formation by the C4'-oxidized abasic site. J. Am. Chem. Soc. 2009, 131:11132-11139.
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 11132-11139
    • Sczepanski, J.T.1    Jacobs, A.C.2    Majumdar, A.3    Greenberg, M.M.4
  • 139
    • 80052932009 scopus 로고    scopus 로고
    • Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides
    • Sczepanski J.T., Hiemstra C.N., Greenberg M.M. Probing DNA interstrand cross-link formation by an oxidized abasic site using nonnative nucleotides. Biorg. Med. Chem. 2011, 19:5788-5793.
    • (2011) Biorg. Med. Chem. , vol.19 , pp. 5788-5793
    • Sczepanski, J.T.1    Hiemstra, C.N.2    Greenberg, M.M.3
  • 140
    • 12044260107 scopus 로고
    • Mechanism of neocarzinostatin action: role of DNA microstructure in determination of chemistry of bistranded oxidative damage
    • Goldberg I.H. Mechanism of neocarzinostatin action: role of DNA microstructure in determination of chemistry of bistranded oxidative damage. Acc. Chem. Res. 1991, 24:191-198.
    • (1991) Acc. Chem. Res. , vol.24 , pp. 191-198
    • Goldberg, I.H.1
  • 141
    • 70350329260 scopus 로고    scopus 로고
    • DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesion
    • Guan L., Greenberg M.M. DNA interstrand cross-link formation by the 1,4-dioxobutane abasic lesion. J. Am. Chem. Soc. 2009, 131:15225-15231.
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 15225-15231
    • Guan, L.1    Greenberg, M.M.2
  • 143
    • 0026303274 scopus 로고
    • The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells
    • Iliakis G. The role of DNA double strand breaks in ionizing radiation-induced killing of eukaryotic cells. Bioessays 1991, 13:185-195.
    • (1991) Bioessays , vol.13 , pp. 185-195
    • Iliakis, G.1
  • 145
    • 0030591651 scopus 로고    scopus 로고
    • DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes
    • Povirk L.F. DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes. Mutat. Res. 1996, 355:71-89.
    • (1996) Mutat. Res. , vol.355 , pp. 71-89
    • Povirk, L.F.1
  • 146
    • 70449642870 scopus 로고    scopus 로고
    • Type II topoisomerase - inhibitors, repair mechanisms and mutations
    • Heisig P. Type II topoisomerase - inhibitors, repair mechanisms and mutations. Mutagenesis 2009, 24:465-469.
    • (2009) Mutagenesis , vol.24 , pp. 465-469
    • Heisig, P.1
  • 148
    • 77955276480 scopus 로고    scopus 로고
    • Radiation induced DNA DSBs: contribution from stalled replication forks?
    • Harper J.V., Anderson J.A., O'Neill P. Radiation induced DNA DSBs: contribution from stalled replication forks?. DNA Repair (Amsterdam) 2010, 9:907-913.
    • (2010) DNA Repair (Amsterdam) , vol.9 , pp. 907-913
    • Harper, J.V.1    Anderson, J.A.2    O'Neill, P.3
  • 149
    • 37149027578 scopus 로고    scopus 로고
    • Processing of DNA damage clusters in human cells: current status of knowledge
    • Georgakilas A.G. Processing of DNA damage clusters in human cells: current status of knowledge. Mol. Biosyst. 2008, 4:30-35.
    • (2008) Mol. Biosyst. , vol.4 , pp. 30-35
    • Georgakilas, A.G.1
  • 150
    • 64549162745 scopus 로고    scopus 로고
    • The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells
    • Kozmin S.G., Sedletska Y., Reynaud-Angelin A., Gasparutto D., Sage E. The formation of double-strand breaks at multiply damaged sites is driven by the kinetics of excision/incision at base damage in eukaryotic cells. Nucleic Acids Res. 2009, 37:1767-1777.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1767-1777
    • Kozmin, S.G.1    Sedletska, Y.2    Reynaud-Angelin, A.3    Gasparutto, D.4    Sage, E.5
  • 151
    • 77950360354 scopus 로고    scopus 로고
    • Hierarchy of lesions processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage
    • Eccles L.J., Lomax M.E., O'Neill P. Hierarchy of lesions processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res. 2010, 38:1123-1134.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 1123-1134
    • Eccles, L.J.1    Lomax, M.E.2    O'Neill, P.3
  • 152
    • 0036086399 scopus 로고    scopus 로고
    • DNA lesion complexity and induction of apoptosis by ionizing radiation
    • Radford I.R. DNA lesion complexity and induction of apoptosis by ionizing radiation. Int. J. Radiat. Biol. 2002, 78:457-466.
    • (2002) Int. J. Radiat. Biol. , vol.78 , pp. 457-466
    • Radford, I.R.1
  • 153
    • 34250654965 scopus 로고    scopus 로고
    • The comet assay: a method to measure DNA damage in individual cells
    • Olive P.L., Banáth J.P. The comet assay: a method to measure DNA damage in individual cells. Nat. Protocol. 2006, 1:23-29.
    • (2006) Nat. Protocol. , vol.1 , pp. 23-29
    • Olive, P.L.1    Banáth, J.P.2
  • 154
    • 84861010003 scopus 로고    scopus 로고
    • Evaluation of the efficacy of radiation-modifyning compounds using γH2AX as a molecular marker of DNA double-strand breaks
    • Mah L.-J., Orlowski C., Ververis K., Vasireddy R., El-Osta A., Karagiannis T.C. Evaluation of the efficacy of radiation-modifyning compounds using γH2AX as a molecular marker of DNA double-strand breaks. Genome Integr. 2011, 2:3.
    • (2011) Genome Integr. , vol.2 , pp. 3
    • Mah, L.-J.1    Orlowski, C.2    Ververis, K.3    Vasireddy, R.4    El-Osta, A.5    Karagiannis, T.C.6
  • 155
    • 84861893199 scopus 로고    scopus 로고
    • Use of γ-H2AX assay to monitor DNA damage and repair in translational cancer research
    • A. Ivashkevich, C.E. Redon, A.J. Nakamura, R.F. Martin, O.A Martin, Use of γ-H2AX assay to monitor DNA damage and repair in translational cancer research, Cancer Lett., (2012), http://dx.doi.org/10.1016/J.canlet.2011.12.05.
    • (2012) Cancer Lett.
    • Ivashkevich, A.1    Redon, C.E.2    Nakamura, A.J.3    Martin, R.F.4    Martin, O.A.5
  • 157
    • 33646769992 scopus 로고    scopus 로고
    • The loss of γH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA damage
    • Bouquet F., Muller C., Salles B. The loss of γH2AX signal is a marker of DNA double strand breaks repair only at low levels of DNA damage. Cell Cycle 2006, 5:1116-1122.
    • (2006) Cell Cycle , vol.5 , pp. 1116-1122
    • Bouquet, F.1    Muller, C.2    Salles, B.3
  • 158
    • 77951977367 scopus 로고    scopus 로고
    • Endogenous DNA breaks: gamma H2AX and the role of telomers
    • Olive P.L. Endogenous DNA breaks: gamma H2AX and the role of telomers. Aging (Albany NY) 2009, 1:154-156.
    • (2009) Aging (Albany NY) , vol.1 , pp. 154-156
    • Olive, P.L.1
  • 160
    • 80053439127 scopus 로고    scopus 로고
    • Phosphorylated H2AX is not an unambiguous marker for DNA double-strand breaks
    • Cleaver J.E., Feeny L., Revet I. Phosphorylated H2AX is not an unambiguous marker for DNA double-strand breaks. Cell Cycle 2011, 10:3223-3224.
    • (2011) Cell Cycle , vol.10 , pp. 3223-3224
    • Cleaver, J.E.1    Feeny, L.2    Revet, I.3
  • 161
    • 0037884963 scopus 로고    scopus 로고
    • Evidence for a lack of DNA double-strand break repair in human cells exposed to very lox X-ray doses
    • Rothkamm K., Lobrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very lox X-ray doses. Proc. Natl. Acad. Sci. USA 2003, 100:5057-5062.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 5057-5062
    • Rothkamm, K.1    Lobrich, M.2
  • 162
    • 77953229115 scopus 로고    scopus 로고
    • The mechanism of double-strand DNA break repair by the nonhomologous DNA end joining pathway
    • Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 181-211
    • Lieber, M.R.1
  • 163
    • 79956215808 scopus 로고    scopus 로고
    • Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways
    • Mladenov E., Iliakis G. Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways. Mutat. Res. 2011, 711:61-72.
    • (2011) Mutat. Res. , vol.711 , pp. 61-72
    • Mladenov, E.1    Iliakis, G.2
  • 164
    • 80655127826 scopus 로고    scopus 로고
    • The role of homologous recombination in radiation-induced double strand break repair
    • Jeggo P.A., Geuting V., Löbrich M. The role of homologous recombination in radiation-induced double strand break repair. Radiother. Oncol. 2011, 101:7-12.
    • (2011) Radiother. Oncol. , vol.101 , pp. 7-12
    • Jeggo, P.A.1    Geuting, V.2    Löbrich, M.3
  • 165
    • 68749100947 scopus 로고    scopus 로고
    • Involvement of nucleotide excision repair and mismatch repair mechanisms in double strand break repair
    • Zhang Y., Rohde L.H., Wu H. Involvement of nucleotide excision repair and mismatch repair mechanisms in double strand break repair. Curr. Genomics 2009, 10:250-258.
    • (2009) Curr. Genomics , vol.10 , pp. 250-258
    • Zhang, Y.1    Rohde, L.H.2    Wu, H.3
  • 166
    • 78650603715 scopus 로고    scopus 로고
    • Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini
    • Datta K., Purkayastha S., Neumann R.D., Pastwa E., Winters T.A. Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini. Radiat. Res. 2011, 175:97-112.
    • (2011) Radiat. Res. , vol.175 , pp. 97-112
    • Datta, K.1    Purkayastha, S.2    Neumann, R.D.3    Pastwa, E.4    Winters, T.A.5
  • 167
  • 168
    • 0036249832 scopus 로고    scopus 로고
    • Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles
    • Pouget J.-P., Frelon S., Ravanat J.-L., Testard I., Odin F., Cadet J. Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles. Radiat. Res. 2002, 157:589-595.
    • (2002) Radiat. Res. , vol.157 , pp. 589-595
    • Pouget, J.-P.1    Frelon, S.2    Ravanat, J.-L.3    Testard, I.4    Odin, F.5    Cadet, J.6
  • 169
    • 33645136996 scopus 로고    scopus 로고
    • Minor contribution of direct ionization to DNA base damage induced by heavy ions
    • Douki T., Ravanat J.-L., Pouget J.-P., Testard I., Cadet J. Minor contribution of direct ionization to DNA base damage induced by heavy ions. Int. J. Radiat. Biol. 2006, 82:119-127.
    • (2006) Int. J. Radiat. Biol. , vol.82 , pp. 119-127
    • Douki, T.1    Ravanat, J.-L.2    Pouget, J.-P.3    Testard, I.4    Cadet, J.5
  • 170
    • 0034753336 scopus 로고    scopus 로고
    • Computational approach for determining the spectrum of DNA damage induced by ionizing radiation
    • Nikjoo H., O'Neill P., Wilson W.E., Goodhead D.T. Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 2001, 156:577-583.
    • (2001) Radiat. Res. , vol.156 , pp. 577-583
    • Nikjoo, H.1    O'Neill, P.2    Wilson, W.E.3    Goodhead, D.T.4
  • 171
    • 2442448170 scopus 로고    scopus 로고
    • A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation
    • Semenenko V.A., Stewart R.D. A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation. Radiat. Res. 2004, 161:451-457.
    • (2004) Radiat. Res. , vol.161 , pp. 451-457
    • Semenenko, V.A.1    Stewart, R.D.2
  • 172
    • 6944248997 scopus 로고    scopus 로고
    • Processing of bistranded abasic DNA clusters in γ-irradiated human hematopoietic cells
    • Georgakilas A.G., Bennett P.V., Wilson D.M., Sutherland B.M. Processing of bistranded abasic DNA clusters in γ-irradiated human hematopoietic cells. Nucleic Acids Res. 2004, 32:5609-5620.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5609-5620
    • Georgakilas, A.G.1    Bennett, P.V.2    Wilson, D.M.3    Sutherland, B.M.4
  • 176
    • 0037046978 scopus 로고    scopus 로고
    • Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400nm) radiation?
    • Song J.M., Milligan J.R., Sutherland B.M. Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400nm) radiation?. Biochemistry 2002, 41:8683-8688.
    • (2002) Biochemistry , vol.41 , pp. 8683-8688
    • Song, J.M.1    Milligan, J.R.2    Sutherland, B.M.3
  • 177
    • 79954619824 scopus 로고    scopus 로고
    • No formation of DNA double-strand breaks and no activation of recombination repair with UVA
    • Rizzo J.L., Dunn J., Rees A., Rünger T.M. No formation of DNA double-strand breaks and no activation of recombination repair with UVA. J. Invest. Dermatol. 2010, 131:1139-1148.
    • (2010) J. Invest. Dermatol. , vol.131 , pp. 1139-1148
    • Rizzo, J.L.1    Dunn, J.2    Rees, A.3    Rünger, T.M.4
  • 178
    • 79954609897 scopus 로고    scopus 로고
    • Oxidatively generated damage to DNA radiation in cells and human skin
    • Cadet J., Douki T. Oxidatively generated damage to DNA radiation in cells and human skin. J. Invest. Dermatol. 2011, 131:1005-1007.
    • (2011) J. Invest. Dermatol. , vol.131 , pp. 1005-1007
    • Cadet, J.1    Douki, T.2
  • 179
    • 80054972492 scopus 로고    scopus 로고
    • ΓH2AX: biomarker of damage or functional participant in DNA repair "all that glitters is not gold"
    • Cleaver J.E. ΓH2AX: biomarker of damage or functional participant in DNA repair "all that glitters is not gold" Photochem. Photobiol. 2011, 87:1230-1239.
    • (2011) Photochem. Photobiol. , vol.87 , pp. 1230-1239
    • Cleaver, J.E.1
  • 180
    • 13744259832 scopus 로고    scopus 로고
    • Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins
    • Eot-Houllier G., Eon-Marchais S., Gasparutto D., Sage E. Processing of a complex multiply damaged DNA site by human cell extracts and purified repair proteins. Nucleic Acids Res. 2005, 33:260-271.
    • (2005) Nucleic Acids Res. , vol.33 , pp. 260-271
    • Eot-Houllier, G.1    Eon-Marchais, S.2    Gasparutto, D.3    Sage, E.4
  • 181
    • 34250831508 scopus 로고    scopus 로고
    • Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences
    • Eot-Houllier G., Gonera M., Gasparutto D., Giustranti C., Sage E. Interplay between DNA N-glycosylases/AP lyases at multiply damaged sites and biological consequences. Nucleic Acids Res. 2007, 35:3355-3366.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 3355-3366
    • Eot-Houllier, G.1    Gonera, M.2    Gasparutto, D.3    Giustranti, C.4    Sage, E.5
  • 182
    • 23644443688 scopus 로고    scopus 로고
    • Repair of tandem base lesions in DNA by human cell extracts generates persisting single-strand breaks
    • Budworth H., Matthemann G., O'Neill P., Dianov G.L. Repair of tandem base lesions in DNA by human cell extracts generates persisting single-strand breaks. J. Mol. Biol. 2005, 351:1020-1029.
    • (2005) J. Mol. Biol. , vol.351 , pp. 1020-1029
    • Budworth, H.1    Matthemann, G.2    O'Neill, P.3    Dianov, G.L.4
  • 183
    • 67949124717 scopus 로고    scopus 로고
    • Processing of thymine glycol in a clustred DNA damage site: mutagenic or cytotoxic
    • Bellon S., Shikazono N., Cunniffe S., Loma M., O'Neill P. Processing of thymine glycol in a clustred DNA damage site: mutagenic or cytotoxic. Nucleic Acids Res. 2009, 37:4430-4440.
    • (2009) Nucleic Acids Res. , vol.37 , pp. 4430-4440
    • Bellon, S.1    Shikazono, N.2    Cunniffe, S.3    Loma, M.4    O'Neill, P.5
  • 184
    • 84858800636 scopus 로고    scopus 로고
    • The mutagenic potential 8-oxoG/single strand break-containing clusters of their relative positions
    • Noguchi M., Urushibara A., Yokoya A., O'Neill P., Shikazono N. The mutagenic potential 8-oxoG/single strand break-containing clusters of their relative positions. Mutat. Res. 2012, 732:34-42.
    • (2012) Mutat. Res. , vol.732 , pp. 34-42
    • Noguchi, M.1    Urushibara, A.2    Yokoya, A.3    O'Neill, P.4    Shikazono, N.5
  • 185
    • 79956197636 scopus 로고    scopus 로고
    • Delayed repair of radiation-induced clustered DNA damage: friend of foe?
    • Eccles L.J., O'Neill P., Lomax M.E. Delayed repair of radiation-induced clustered DNA damage: friend of foe?. Mutat. Res. 2011, 711:134-141.
    • (2011) Mutat. Res. , vol.711 , pp. 134-141
    • Eccles, L.J.1    O'Neill, P.2    Lomax, M.E.3
  • 186
    • 79957686784 scopus 로고    scopus 로고
    • Unrepaired clustered DNA lesions induce chromosome breakage in human cells
    • Asaithamby A., Hu B., Chen D.J. Unrepaired clustered DNA lesions induce chromosome breakage in human cells. Proc. Natl. Acad. Sci. USA 2011, 108:8293-8298.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 8293-8298
    • Asaithamby, A.1    Hu, B.2    Chen, D.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.