Autophagic degradation of nuclear components in mammalian cells

Autophagy

Volumn 5, Issue 6, 2009, Pages 795-804

  Park, Young Eun ^a,b   Hayashi, Yukiko K ^a   Bonne, Gisèle ^c,d   Arimura, Takuro ^e   Noguchi, Satoru ^a   Nonaka, Ikuya ^a   Nishino, Ichizo ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b Pusan National University Hospital   (South Korea)

^c INSERM   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

A type lamins; Autophagy; Emerin; Nuclear envelopathies; Nucleus

Indexed keywords

EMERIN; GREEN FLUORESCENT PROTEIN; LAMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FIBROBLAST; GENE MUTATION; HEART MUSCLE; HUMAN; HUMAN TISSUE; LYSOSOME; MAMMAL CELL; MOUSE; NONHUMAN; PHAGOSOME; PROTEIN DEGRADATION; SKELETAL MUSCLE; UPREGULATION;

MAMMALIA;

EID: 69449083200     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.8901     Document Type: Article

References (49)

1. Bonne G, Di Barletta MR, Varnous S, Becane HM, Hammouda EH, Merlini L, et al. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy. Nat Genet 1999; 21:285-288 (Pubitemid 29124935)
2. Raffaele Di Barletta M, Ricci E, Galluzzi G, Tonali P, Mora M, Morandi L, et al. Different mutations in the LMNA gene cause autosomal dominant and autosomal recessive Emery-Dreifuss muscular dystrophy. Am J Hum Genet 2000; 66:1407-1412 (Pubitemid 30468795)
3. Muchir A, Bonne G, van der Kooi AJ, van Meegen M, Baas F, Bolhuis PA, et al. Identification of mutations in the gene encoding lamins A/C in autosomal dominant limb girdle muscular dystrophy with atrioventricular conduction disturbances (LGMD1B). Hum Mol Genet 2000; 9:1453-1459 (Pubitemid 30312494)
4. Fatkin D, MacRae C, Sasaki T, Wolff MR, Porcu M, Frenneaux M, et al. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. N Engl J Med 1999; 341:1715-1724
5. Becane HM, Bonne G, Varnous S, Muchir A, Ortega V, Hammouda EH, et al. High incidence of sudden death with conduction system and myocardial disease due to lamins A and C gene mutation. Pacing Clin Electrophysiol 2000; 23:1661-1666
6. Cao H, Hegele RA. Nuclear lamin A/C R482Q mutation in canadian kindreds with Dunnigan-type familial partial lipodystrophy. Hum Mol Genet 2000; 9:109-112 (Pubitemid 30145295)
7. De Sandre-Giovannoli A, Chaouch M, Kozlov S, Vallat JM, Tazir M, Kassouri N, et al. Homozygous defects in LMNA, encoding lamin A/C nuclear-envelope proteins, cause autosomal recessive axonal neuropathy in human (Charcot-Marie-Tooth disorder type 2) and mouse. Am J Hum Genet 2002; 70:726-736 (Pubitemid 34177926)
8. De Sandre-Giovannoli A, Bernard R, Cau P, Navarro C, Amiel J, Boccaccio I, et al. Lamin a truncation in Hutchinson-Gilford progeria. Science 2003; 300:2055.
9. Eriksson M, Brown WT, Gordon LB, Glynn MW, Singer J, Scott L, et al. Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature 2003; 423:293-298 (Pubitemid 40852699)
10. Bione S, Maestrini E, Rivella S, Mancini M, Regis S, Romeo G, Toniolo D. Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy. Nat Genet 1994; 8:323-327 (Pubitemid 24375595)
11. Ura S, Hayashi YK, Goto K, Astejada MN, Murakami T, Nagato M, et al. Limb-girdle muscular dystrophy due to emerin gene mutations. Arch Neurol 2007; 64:1038-1041 (Pubitemid 47048007)
12. Karst ML, Herron KJ, Olson TM. X-linked nonsyndromic sinus node dysfunction and atrial fibrillation caused by emerin mutation. J Cardiovasc Electrophysiol 2008; 19:510-515
13. Ben Yaou R, Toutain A, Arimura T, Demay L, Massart C, Peccate C, et al. Multitissular involvement in a family with LMNA and EMD mutations: Role of digenic mechanism? Neurology 2007; 68:1883-1894
14. Broers JL, Peeters EA, Kuijpers HJ, Endert J, Bouten CV, Oomens CW, et al. Decreased mechanical stiffness in LMNA-/- cells is caused by defective nucleo-cytoskeletal integrity: implications for the development of laminopathies. Hum Mol Genet 2004; 13:2567-2580 (Pubitemid 39485406)
15. Lammerding J, Schulze PC, Takahashi T, Kozlov S, Sullivan T, Kamm RD, et al. Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction. J Clin Invest 2004; 113:370-378 (Pubitemid 38544181)
16. Sakaki M, Koike H, Takahashi N, Sasagawa N, Tomioka S, Arahata K, Ishiura S. Interaction between emerin and nuclear lamins. J Biochem 2001; 129:321-327
17. Mislow JM, Holaska JM, Kim MS, Lee KK, Segura-Totten M, Wilson KL, McNally EM. Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro. FEBS Lett 2002; 525:135-140 (Pubitemid 34886389)
18. Bengtsson L, Wilson KL. Multiple and surprising new functions for emerin, a nuclear membrane protein. Curr Opin Cell Biol 2004; 16:73-79 (Pubitemid 38368155)
19. Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, et al. Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. J Cell Sci 2005; 118:673-687 (Pubitemid 40372577)
20. Sabatelli P, Lattanzi G, Ognibene A, Columbaro M, Capanni C, Merlini L, et al. Nuclear alterations in autosomal-dominant Emery-Dreifuss muscular dystrophy. Muscle Nerve 2001; 24:826-829 (Pubitemid 32476531)
21. Park YE, Hayashi YK, Goto K, Nonaka I, Noguchi S, Nishino I. Nuclear Changes in Skeletal Muscles Extend to Satellite Cells in AD-EDMD/LGMD1B. Neuromuscul Disord 2008; In Press.
22. Fidzianska A, Toniolo D, Hausmanowa-Petrusewicz I. Ultrastructural abnormality of sarcolemmal nuclei in Emery-Dreifuss muscular dystrophy (EDMD). J Neurol Sci 1998; 159:88-93. (Pubitemid 28365889)
23. Fidzianska A, Hausmanowa-Petrusewicz I. Architectural abnormalities in muscle nuclei. Ultrastructural differences between X-linked and autosomal dominant forms of EDMD. J Neurol Sci 2003; 210:47-51. (Pubitemid 36539403)
24. Fidzianska A, Bilinska ZT, Tesson F, Wagner T, Walski M, Grzybowski J, et al. Obliteration of cardiomyocyte nuclear architecture in a patient with LMNA gene mutation. J Neurol Sci 2008; 271:91-96
25. Ozawa R, Hayashi YK, Ogawa M, Kurokawa R, Matsumoto H, Noguchi S, et al. Emerin-lacking mice show minimal motor and cardiac dysfunctions with nuclear-associated vacuoles. Am J Pathol 2006; 168:907-917 (Pubitemid 43327743)
26. Harding TM, Morano KA, Scott SV, Klionsky DJ. Isolation and characterization of yeast mutants in the cytoplasm to vacuole protein targeting pathway. J Cell Biol 1995; 131:591-602.
27. Klionsky DJ, Cregg JM, Dunn WA Jr, Emr SD, Sakai Y, Sandoval IV, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003; 5:539-545 (Pubitemid 37243044)
28. Tanida I, Ueno T, Kominami E. LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 2004; 36:2503-2518 (Pubitemid 39119762)
29. Dunn WA Jr, Cregg JM, Kiel JA, van der Klei IJ, Oku M, Sakai Y, et al. Pexophagy: the selective autophagy of peroxisomes. Autophagy 2005; 1:75-83.
30. Kim I, Rodriguez-Enriquez S, Lemasters JJ. Selective degradation of mitochondria by mitophagy. Arch Biochem Biophys 2007; 462:245-253
31. Bernales S, Schuck S, Walter P. ER-phagy: selective autophagy of the endoplasmic reticulum. Autophagy 2007; 3:285-287 (Pubitemid 46752700)
32. Muchir A, van Engelen BG, Lammens M, Mislow JM, McNally E, Schwartz K, Bonne G. Nuclear envelope alterations in fibroblasts from LGMD1B patients carrying nonsense Y259X heterozygous or homozygous mutation in lamin A/C gene. Exp Cell Res 2003; 291:352-362 (Pubitemid 37492866)
33. Muchir A, Medioni J, Laluc M, Massart C, Arimura T, van der Kooi AJ, et al. Nuclear envelope alterations in fibroblasts from patients with muscular dystrophy, cardiomyopathy and partial lipodystrophy carrying lamin A/C gene mutations. Muscle Nerve 2004; 30:444-450 (Pubitemid 39288147)
34. Kabeya Y, Mizushima N, Ueno T, Yamamoto A, Kirisako T, Noda T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000; 19:5720-5728 (Pubitemid 30828328)
35. Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004; 15:1101-1111
36. Xie Z, Klionsky DJ. Autophagosome formation: core machinery and adaptations. Nat Cell Biol 2007; 9:1102-1109 (Pubitemid 47500484)
37. Young AR, Chan EY, Hu XW, Kochl R, Crawshaw SG, High S, et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 2006; 119:3888-3900 (Pubitemid 44614440)
38. Gutierrez MG, Munafo DB, Beron W, Colombo MI. Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. J Cell Sci 2004; 117:2687-2697 (Pubitemid 38997252)
39. Fillingham J, Keogh MC, Krogan NJ. GammaH2AX and its role in DNA double-strand break repair. Biochem Cell Biol 2006; 84:568-577 (Pubitemid 44703660)
40. Tanida I, Minematsu-Ikeguchi N, Ueno T, Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005; 1:84-91.
41. Nakagawa I, Amano A, Mizushima N, Yamamoto A, Yamaguchi H, Kamimoto T, et al. Autophagy defends cells against invading group A Streptococcus. Science 2004; 306:1037-1040 (Pubitemid 39482907)
42. Kvam E, Goldfarb DS. Nucleus-vacuole junctions and piecemeal microautophagy of the nucleus in S. cerevisiae. Autophagy 2007; 3:85-92. (Pubitemid 46449095)
43. Kvam E, Goldfarb DS. Nucleus-vacuole junctions in yeast: anatomy of a membrane contact site. Biochem Soc Trans 2006; 34:340-342 (Pubitemid 43953981)
44. Krick R, Muehe Y, Prick T, Bremer S, Schlotterhose P, Eskelinen EL, et al. Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell 2008; 19:4492-4505
45. Marino G, Ugalde AP, Salvador-Montoliu N, Varela I, Quiros PM, Cadinanos J, et al. Premature aging in mice activates a systemic metabolic response involving autophagy induction. Hum Mol Genet 2008; 17:2196-2211 (Pubitemid 351911988)
46. Pendas AM, Zhou Z, Cadinanos J, Freije JM, Wang J, Hultenby K, et al. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice. Nat Genet 2002; 31:94-99 (Pubitemid 34887646)
47. Arimura T, Helbling-Leclerc A, Massart C, Varnous S, Niel F, Lacene E, et al. Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies. Hum Mol Genet 2005; 14:155-169 (Pubitemid 40123471)
48. Sullivan T, Escalante-Alcalde D, Bhatt H, Anver M, Bhat N, Nagashima K, et al. Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophy. J Cell Biol 1999; 147:913-920
49. Carra S, Seguin SJ, Lambert H, Landry J. HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy. J Biol Chem 2008; 283:1437-1444