메뉴 건너뛰기




Volumn 13, Issue 4, 2007, Pages 1315-1321

DNA mismatch repair initiates 6-thioguanine-induced autophagy through p53 activation in human tumor cells

Author keywords

[No Author keywords available]

Indexed keywords

PIFITHRIN ALPHA; PROTEIN P53; SHORT HAIRPIN RNA; TIOGUANINE;

EID: 33947209622     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-1517     Document Type: Article
Times cited : (76)

References (42)
  • 1
    • 0036198664 scopus 로고    scopus 로고
    • DNA mismatch repair and mutation avoidance pathways
    • Marti TM, Kunz C, Fleck O. DNA mismatch repair and mutation avoidance pathways. J Cell Physiol 2002;191:28-41.
    • (2002) J Cell Physiol , vol.191 , pp. 28-41
    • Marti, T.M.1    Kunz, C.2    Fleck, O.3
  • 2
    • 0029943449 scopus 로고    scopus 로고
    • Mismatch repair in replication fidelity, genetic recombination, and cancer biology
    • Modrich P, Lahue R. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. Annu Rev Biochem 1996;65:101-33.
    • (1996) Annu Rev Biochem , vol.65 , pp. 101-133
    • Modrich, P.1    Lahue, R.2
  • 4
    • 0034500024 scopus 로고    scopus 로고
    • DNA mismatch repair and genetic instability
    • Harfe BD, Jinks-Robertson S. DNA mismatch repair and genetic instability. Annu Rev Genet 2000;34:359-99.
    • (2000) Annu Rev Genet , vol.34 , pp. 359-399
    • Harfe, B.D.1    Jinks-Robertson, S.2
  • 5
    • 0036252540 scopus 로고    scopus 로고
    • DNA mismatch repair defects: Role in colorectal carcinogenesis
    • Jacob S, Praz F. DNA mismatch repair defects: role in colorectal carcinogenesis. Biochimie 2002;84:27-47.
    • (2002) Biochimie , vol.84 , pp. 27-47
    • Jacob, S.1    Praz, F.2
  • 6
    • 0031278322 scopus 로고    scopus 로고
    • Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
    • Miyaki M, Konishi M, Tanaka K, et al. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet 1997;17:271-2.
    • (1997) Nat Genet , vol.17 , pp. 271-272
    • Miyaki, M.1    Konishi, M.2    Tanaka, K.3
  • 7
  • 8
    • 20444501376 scopus 로고    scopus 로고
    • MSH2 missense mutations alter cisplatin cytotoxicity and promote cisplatin-induced genome instability
    • Clodfelter JE, Gentry MB, Drotschmann K. MSH2 missense mutations alter cisplatin cytotoxicity and promote cisplatin-induced genome instability. Nucleic Acids Res 2005;33:3323-30.
    • (2005) Nucleic Acids Res , vol.33 , pp. 3323-3330
    • Clodfelter, J.E.1    Gentry, M.B.2    Drotschmann, K.3
  • 9
    • 0027369717 scopus 로고
    • Genetic consequences of tolerance to methylation DNA damage in mammalian cells
    • Aquilina G, Biondo R, Dogliotti E, Bignami M. Genetic consequences of tolerance to methylation DNA damage in mammalian cells. Carcinogenesis 1993;14:2097-103.
    • (1993) Carcinogenesis , vol.14 , pp. 2097-2103
    • Aquilina, G.1    Biondo, R.2    Dogliotti, E.3    Bignami, M.4
  • 10
    • 0037226473 scopus 로고    scopus 로고
    • The mismatch repair system is required for S-phase checkpoint activation
    • Brown KD, Rathi A, Kamath R, et al. The mismatch repair system is required for S-phase checkpoint activation. Nat Genet 2003;33:80-4.
    • (2003) Nat Genet , vol.33 , pp. 80-84
    • Brown, K.D.1    Rathi, A.2    Kamath, R.3
  • 11
    • 3242885728 scopus 로고    scopus 로고
    • Mismatch repair and DNA damage signalling
    • Stojic L, Brun R, Jiricny J. Mismatch repair and DNA damage signalling. DNA Repair (Amst) 2004;3:1091-101.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1091-1101
    • Stojic, L.1    Brun, R.2    Jiricny, J.3
  • 12
    • 0035863399 scopus 로고    scopus 로고
    • A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles
    • Paglin S, Hollister T, Delohery T, et al. A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. Cancer Res 2001;61:439-44.
    • (2001) Cancer Res , vol.61 , pp. 439-444
    • Paglin, S.1    Hollister, T.2    Delohery, T.3
  • 13
  • 14
    • 0025363276 scopus 로고
    • Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
    • Dunn WA, Jr. Studies on the mechanisms of autophagy: formation of the autophagic vacuole. J Cell Biol 1990;110:1923-33.
    • (1990) J Cell Biol , vol.110 , pp. 1923-1933
    • Dunn Jr., W.A.1
  • 15
    • 0025340880 scopus 로고
    • Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
    • Dunn WA, Jr. Studies on the mechanisms of autophagy: maturation of the autophagic vacuole. J Cell Biol 1990;110:1935-45.
    • (1990) J Cell Biol , vol.110 , pp. 1935-1945
    • Dunn Jr., W.A.1
  • 16
    • 8344242220 scopus 로고    scopus 로고
    • Autophagy in health and disease: A double-edged sword
    • Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science 2004;306:990-5.
    • (2004) Science , vol.306 , pp. 990-995
    • Shintani, T.1    Klionsky, D.J.2
  • 17
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: An innocent convict?
    • Levine B, Yuan J. Autophagy in cell death: an innocent convict? J Clin Invest 2005;115:2679-88.
    • (2005) J Clin Invest , vol.115 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 18
    • 33646271855 scopus 로고    scopus 로고
    • A matter of life or death (or both): Understanding autophagy in cancer
    • Hait WN, Jin S, Yang JM. A matter of life or death (or both): understanding autophagy in cancer. Clin Cancer Res 2006;12:1961-5.
    • (2006) Clin Cancer Res , vol.12 , pp. 1961-1965
    • Hait, W.N.1    Jin, S.2    Yang, J.M.3
  • 19
    • 0028350601 scopus 로고
    • Mutation of a mutL homolog in hereditary colon cancer
    • Papadopoulos N, Nicolaides NC, Wei YF, et al. Mutation of a mutL homolog in hereditary colon cancer. Science 1994;263:1625-9.
    • (1994) Science , vol.263 , pp. 1625-1629
    • Papadopoulos, N.1    Nicolaides, N.C.2    Wei, Y.F.3
  • 20
    • 0035418619 scopus 로고    scopus 로고
    • The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells
    • Jacob S, Aguado M, Fallik D, Praz F. The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells. Cancer Res 2001;61:6555-62.
    • (2001) Cancer Res , vol.61 , pp. 6555-6562
    • Jacob, S.1    Aguado, M.2    Fallik, D.3    Praz, F.4
  • 21
    • 0028301255 scopus 로고
    • Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability
    • Umar A, Boyer JC, Thomas DC, et al. Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. J Biol Chem 1994;269:14367-70.
    • (1994) J Biol Chem , vol.269 , pp. 14367-14370
    • Umar, A.1    Boyer, J.C.2    Thomas, D.C.3
  • 22
    • 0030776227 scopus 로고    scopus 로고
    • Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6
    • Umar A, Koi M, Risinger JI, et al. Correction of hypermutability, N-methyl-N′-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res 1997;57:3949-55.
    • (1997) Cancer Res , vol.57 , pp. 3949-3955
    • Umar, A.1    Koi, M.2    Risinger, J.I.3
  • 23
    • 0034329418 scopus 로고    scopus 로고
    • LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
    • Kabeya Y, Mizushima N, Ueno T, et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 2000;19:5720-8.
    • (2000) EMBO J , vol.19 , pp. 5720-5728
    • Kabeya, Y.1    Mizushima, N.2    Ueno, T.3
  • 24
    • 32244442749 scopus 로고    scopus 로고
    • Functional specificity of the mammalian Beclin-Vps34 Pl 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
    • Zeng X, Overmeyer JH, Maltese WA. Functional specificity of the mammalian Beclin-Vps34 Pl 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking. J Cell Sci 2006;119:259-70.
    • (2006) J Cell Sci , vol.119 , pp. 259-270
    • Zeng, X.1    Overmeyer, J.H.2    Maltese, W.A.3
  • 25
    • 0035911162 scopus 로고    scopus 로고
    • Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells
    • Mizushima N, Yamamoto A, Hatano M, et al. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J Cell Biol 2001;152:657-68.
    • (2001) J Cell Biol , vol.152 , pp. 657-668
    • Mizushima, N.1    Yamamoto, A.2    Hatano, M.3
  • 27
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. Methods for monitoring autophagy. Int J Biochem Cell Biol 2004;36:2491-502.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 28
    • 0028708948 scopus 로고
    • Lysosomal proton pump activity: Supravital cell staining with acridine orange differentiates leukocyte subpopulations
    • Traganos F, Darzynkiewicz Z. Lysosomal proton pump activity: supravital cell staining with acridine orange differentiates leukocyte subpopulations. Methods Cell Biol 1994;41:185-94.
    • (1994) Methods Cell Biol , vol.41 , pp. 185-194
    • Traganos, F.1    Darzynkiewicz, Z.2
  • 29
    • 20444363122 scopus 로고    scopus 로고
    • The coordinate regulation of the p53 and mTOR pathways in cells
    • Feng Z, Zhang H, Levine AJ, Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc Natl Acad Sci U S A 2005;102:8204-9.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 8204-8209
    • Feng, Z.1    Zhang, H.2    Levine, A.J.3    Jin, S.4
  • 30
    • 0033543728 scopus 로고    scopus 로고
    • A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
    • Komarov PG, Komarova EA, Kondratov RV, et al. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 1999;285:1733-7.
    • (1999) Science , vol.285 , pp. 1733-1737
    • Komarov, P.G.1    Komarova, E.A.2    Kondratov, R.V.3
  • 31
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry WS, Tokino T, Velculescu VE, et al. WAF1, a potential mediator of p53 tumor suppression. Cell 1993;75:817-25.
    • (1993) Cell , vol.75 , pp. 817-825
    • el-Deiry, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 32
    • 33645322935 scopus 로고    scopus 로고
    • Signalling cell cycle arrest and cell death through the MMR System
    • O'Brien V, Brown R. Signalling cell cycle arrest and cell death through the MMR System. Carcinogenesis 2006;27:682-92.
    • (2006) Carcinogenesis , vol.27 , pp. 682-692
    • O'Brien, V.1    Brown, R.2
  • 33
    • 0037881803 scopus 로고    scopus 로고
    • Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1
    • Cejka P, Stojic L, Mojas N, et al. Methylation-induced G(2)/M arrest requires a full complement of the mismatch repair protein hMLH1. EMBO J 2003;22:2245-54.
    • (2003) EMBO J , vol.22 , pp. 2245-2254
    • Cejka, P.1    Stojic, L.2    Mojas, N.3
  • 35
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L, Elledge SJ. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003;300:1542-8.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 36
    • 0035253615 scopus 로고    scopus 로고
    • networking cellular responses to DNA damage
    • and ATR
    • Shiloh Y. ATM and ATR: networking cellular responses to DNA damage. Curr Opin Genet Dev 2001;11:71-7.
    • (2001) Curr Opin Genet Dev , vol.11 , pp. 71-77
    • Shiloh, Y.A.1
  • 37
    • 27644466759 scopus 로고    scopus 로고
    • Autophagy and signaling: Their role in cell survival and cell death
    • Codogno P, Meijer AJ. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 2005;12 Suppl 2:1509-18.
    • (2005) Cell Death Differ , vol.12 , Issue.SUPPL. 2 , pp. 1509-1518
    • Codogno, P.1    Meijer, A.J.2
  • 38
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, et al. Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 2005;120:237-48.
    • (2005) Cell , vol.120 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3
  • 39
    • 10344262564 scopus 로고    scopus 로고
    • Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
    • Shimizu S, Kanaseki T, Mizushima N, et al. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes. Nat Cell Biol 2004;6:1221-8.
    • (2004) Nat Cell Biol , vol.6 , pp. 1221-1228
    • Shimizu, S.1    Kanaseki, T.2    Mizushima, N.3
  • 40
    • 2642553881 scopus 로고    scopus 로고
    • Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8
    • Yu L, Alva A, Su H, et al. Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8. Science 2004;304:1500-2.
    • (2004) Science , vol.304 , pp. 1500-1502
    • Yu, L.1    Alva, A.2    Su, H.3
  • 42
    • 33745282435 scopus 로고    scopus 로고
    • Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells
    • Herman-Antosiewicz A, Johnson DE, Singh SV. Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells. Cancer Res 2006;66:5828-35.
    • (2006) Cancer Res , vol.66 , pp. 5828-5835
    • Herman-Antosiewicz, A.1    Johnson, D.E.2    Singh, S.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.