5-Methoxyflavanone induces cell cycle arrest at the G2/M phase, apoptosis and autophagy in HCT116 human colon cancer cells

Toxicology and Applied Pharmacology

Volumn 254, Issue 3, 2011, Pages 288-298

  Shin, Soon Young ^a,b   Hyun, Jiye ^b   Yu, Jae Ran ^c   Lim, Yoongho ^b   Lee, Young Han ^a,b  

^a Konkuk University Hospital   (South Korea)

^b Konkuk University   (South Korea)

^c Konkuk University School of Medicine   (South Korea)

Author keywords

5 methoxyflavanone; Apoptosis; Autophagy; Caspase; DNA damage checkpoint

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 6 (1 THIANTHRENYL) 4 PYRANONE; 5 METHOXYFLAVANONE; ANTINEOPLASTIC AGENT; ATM PROTEIN; CASPASE 2; CASPASE 7; CHECKPOINT KINASE 2; CYCLIN A1; CYCLIN B1; FLAVONOID; GREEN FLUORESCENT PROTEIN; HISTONE H2AX; PROTEIN P53; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL STRAIN HCT116; CLONOGENESIS; COLON CANCER; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DRUG BIOAVAILABILITY; DRUG MECHANISM; DRUG STABILITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL DIVISION; CELL SURVIVAL; FLAVONES; G2 PHASE; HCT116 CELLS; HUMANS;

ATAXIA TELANGIECTASIA;

EID: 79960058652     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.05.003     Document Type: Article

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