-
1
-
-
0033023072
-
New treatment strategies for malignant gliomas
-
Avgeropoulos NG, Batchelor TT. New treatment strategies for malignant gliomas. Oncologist 1999;4:209-24.
-
(1999)
Oncologist
, vol.4
, pp. 209-224
-
-
Avgeropoulos, N.G.1
Batchelor, T.T.2
-
3
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005;352:987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
5
-
-
33645105856
-
6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells
-
6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells. J Neurochem 2006;96:766 -76.
-
(2006)
J Neurochem
, vol.96
, pp. 766-776
-
-
Hermisson, M.1
Klumpp, A.2
Wick, W.3
-
6
-
-
0031705691
-
p53 and brain tumors: From gene mutations to gene therapy
-
Fulci G, Ishii N, Van Meir EG. p53 and brain tumors: from gene mutations to gene therapy. Brain Pathol 1998;8:599-613.
-
(1998)
Brain Pathol
, vol.8
, pp. 599-613
-
-
Fulci, G.1
Ishii, N.2
Van Meir, E.G.3
-
7
-
-
37549042449
-
Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: P53 determines the switch by regulating XPC, DDB2, and DNA double-strand breaks
-
Batista LF, Roos WP, Christmann M, Menck CF, Kaina B. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating XPC, DDB2, and DNA double-strand breaks. Cancer Res 2007;67:11886-95.
-
(2007)
Cancer Res
, vol.67
, pp. 11886-11895
-
-
Batista, L.F.1
Roos, W.P.2
Christmann, M.3
Menck, C.F.4
Kaina, B.5
-
8
-
-
12344282013
-
DNA interstrand crosslinks: Natural and drug-induced DNA adducts that induce unique cellular responses
-
Scharer OD. DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses. Chem Bio Chem 2005;6:27-32.
-
(2005)
Chem Bio Chem
, vol.6
, pp. 27-32
-
-
Scharer, O.D.1
-
9
-
-
33244478595
-
The eureka enzyme: The discovery of DNA polymerase
-
Friedberg EC. The eureka enzyme: the discovery of DNA polymerase. Nat Rev Mol Cell Biol 2006;7:143-7.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 143-147
-
-
Friedberg, E.C.1
-
10
-
-
59349109196
-
How DNA lesions are turned into powerful killing structures: Insights from UV-induced apoptosis
-
doi:10.1016/j mrrev.2008.09.001
-
Batista LF, Kaina B, Meneghini R, Menck CF. How DNA lesions are turned into powerful killing structures: Insights from UV-induced apoptosis. Mutat Res 2008, doi:10.1016/j mrrev.2008.09.001.
-
Mutat Res
, vol.2008
-
-
Batista, L.F.1
Kaina, B.2
Meneghini, R.3
Menck, C.F.4
-
12
-
-
0942278966
-
The eukaryotic nucleotide excision repairpathway
-
Costa RM, Chigancas V, Galhardo Rda S, Carvalho H, Menck CF. The eukaryotic nucleotide excision repairpathway. Biochimie 2003;85:1083-99.
-
(2003)
Biochimie
, vol.85
, pp. 1083-1099
-
-
Costa, R.M.1
Chigancas, V.2
Galhardo Rda, S.3
Carvalho, H.4
Menck, C.F.5
-
13
-
-
0035921686
-
Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation
-
Dunkern TR, Fritz G, Kaina B. Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation. Oncogene 2001;20:6026-38.
-
(2001)
Oncogene
, vol.20
, pp. 6026-6038
-
-
Dunkern, T.R.1
Fritz, G.2
Kaina, B.3
-
14
-
-
0036790477
-
Photorepair of RNA polymerase arrest and apoptosis after ultraviolet irradiation in normal and XPB deficient rodent cells
-
Chigancas V, Batista LF, Brumatti G, Amarante-Mendes GP, Yasui A, Menck CF. Photorepair of RNA polymerase arrest and apoptosis after ultraviolet irradiation in normal and XPB deficient rodent cells. Cell Death Differ 2002;9:1099-107.
-
(2002)
Cell Death Differ
, vol.9
, pp. 1099-1107
-
-
Chigancas, V.1
Batista, L.F.2
Brumatti, G.3
Amarante-Mendes, G.P.4
Yasui, A.5
Menck, C.F.6
-
15
-
-
0343569966
-
Photorepair prevents ultraviolet-induced apoptosis in human cells expressing the marsupial photolyase gene
-
Chigancas V, Miyaji EN, Muotri AR, et al. Photorepair prevents ultraviolet-induced apoptosis in human cells expressing the marsupial photolyase gene. Cancer Res 2000;60:2458 -63.
-
(2000)
Cancer Res
, vol.60
, pp. 2458-2463
-
-
Chigancas, V.1
Miyaji, E.N.2
Muotri, A.R.3
-
16
-
-
24044506283
-
Regulation of DNA damage recognition and nucleotide excision repair: Anotherrole for p53
-
Ford JM. Regulation of DNA damage recognition and nucleotide excision repair: anotherrole for p53. Mutat Res 2005;577:195-202.
-
(2005)
Mutat Res
, vol.577
, pp. 195-202
-
-
Ford, J.M.1
-
17
-
-
0036791008
-
p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene
-
Adimoolam S, Ford JM. p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene. Proc Natl Acad Sci U S A 2002;99:12985-90.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12985-12990
-
-
Adimoolam, S.1
Ford, J.M.2
-
18
-
-
0000516293
-
Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
-
Hwang BJ, Ford JM, Hanawalt PC, Chu G. Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc Natl Acad Sci U S A 1999;96:424-8.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 424-428
-
-
Hwang, B.J.1
Ford, J.M.2
Hanawalt, P.C.3
Chu, G.4
-
19
-
-
0028919069
-
Involvement of the p53 tumor suppressor in repair of U.V.-type DNA damage
-
Smith ML, Chen IT, Zhan Q, O'Connor PM, Fornace AJ, Jr. Involvement of the p53 tumor suppressor in repair of U.V.-type DNA damage. Oncogene 1995;10:1053-9.
-
(1995)
Oncogene
, vol.10
, pp. 1053-1059
-
-
Smith, M.L.1
Chen, I.T.2
Zhan, Q.3
O'Connor, P.M.4
Fornace Jr., A.J.5
-
20
-
-
0344441926
-
CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death
-
Wischhusen J, Naumann U, Ohgaki H, Rastinejad F, Weller M. CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death. Oncogene 2003;22:8233 -45.
-
(2003)
Oncogene
, vol.22
, pp. 8233-8245
-
-
Wischhusen, J.1
Naumann, U.2
Ohgaki, H.3
Rastinejad, F.4
Weller, M.5
-
21
-
-
33746973285
-
An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria
-
Andressoo JO, Mitchell JR, de Wit J, et al. An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria. Cancer Cell 2006;10:121 -32.
-
(2006)
Cancer Cell
, vol.10
, pp. 121-132
-
-
Andressoo, J.O.1
Mitchell, J.R.2
de Wit, J.3
-
22
-
-
0029785723
-
Blockage of RNA polymerase as a possible trigger for U.V. light-induced apoptosis
-
Ljungman M, Zhang F. Blockage of RNA polymerase as a possible trigger for U.V. light-induced apoptosis. Oncogene 1996;13:823-31.
-
(1996)
Oncogene
, vol.13
, pp. 823-831
-
-
Ljungman, M.1
Zhang, F.2
-
23
-
-
33745823547
-
Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells
-
Batista LF, Chigancas V, Brumatti G, Amarante-Mendes GP, Menck CF. Involvement of DNA replication in ultraviolet-induced apoptosis of mammalian cells. Apoptosis 2006;11:1139-48.
-
(2006)
Apoptosis
, vol.11
, pp. 1139-1148
-
-
Batista, L.F.1
Chigancas, V.2
Brumatti, G.3
Amarante-Mendes, G.P.4
Menck, C.F.5
-
24
-
-
0142027948
-
Ways of dying: Multiple pathways to apoptosis
-
Adams JM. Ways of dying: multiple pathways to apoptosis. Genes Dev 2003;17:2481 -95.
-
(2003)
Genes Dev
, vol.17
, pp. 2481-2495
-
-
Adams, J.M.1
-
25
-
-
33745274726
-
Mitochondria: Dynamic organelles in disease, aging, and development
-
Chan DC. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006;125:1241 -52.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
26
-
-
21644455492
-
p53 in cancer: A paradigm for modern management of cancer
-
Steele RJ, Lane DP. p53 in cancer: a paradigm for modern management of cancer. Surgeon 2005;3:197-205.
-
(2005)
Surgeon
, vol.3
, pp. 197-205
-
-
Steele, R.J.1
Lane, D.P.2
-
27
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan S, Smith ML, Rivet DJ II, et al. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 1995;55:1649 -54.
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet II, D.J.3
-
28
-
-
0034689558
-
p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation
-
El-Mahdy MA, Hamada FM, Wani MA, Zhu Q, Wani AA. p53-degradation by HPV-16 E6 preferentially affects the removal of cyclobutane pyrimidine dimers from non-transcribed strand and sensitizes mammary epithelial cells to UV-irradiation. Mutat Res 2000;459:135-45.
-
(2000)
Mutat Res
, vol.459
, pp. 135-145
-
-
El-Mahdy, M.A.1
Hamada, F.M.2
Wani, M.A.3
Zhu, Q.4
Wani, A.A.5
-
29
-
-
4544259868
-
-
Ljungman M, Lane DP. Transcription-guarding the genome by sensing DNA damage. Nat Rev Cancer2004;4:727-37.
-
Ljungman M, Lane DP. Transcription-guarding the genome by sensing DNA damage. Nat Rev Cancer2004;4:727-37.
-
-
-
-
30
-
-
0036154027
-
Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamstercells
-
Dunkern TR, Kaina B. Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamstercells. Mol Biol Cell 2002;13:348-61.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 348-361
-
-
Dunkern, T.R.1
Kaina, B.2
-
31
-
-
0345686477
-
Effect of cell confluence on ultraviolet light apoptotic responses in DNA repair deficient cells
-
Carvalho H, da Costa RM, Chigancas V, et al. Effect of cell confluence on ultraviolet light apoptotic responses in DNA repair deficient cells. Mutat Res 2003;544:159-66.
-
(2003)
Mutat Res
, vol.544
, pp. 159-166
-
-
Carvalho, H.1
da Costa, R.M.2
Chigancas, V.3
-
32
-
-
26444489119
-
Connected to death: The (unexpurgated) mitochondrial pathway of apoptosis
-
Spierings D, McStay G, Saleh M, et al. Connected to death: the (unexpurgated) mitochondrial pathway of apoptosis. Science 2005;310:66-7.
-
(2005)
Science
, vol.310
, pp. 66-67
-
-
Spierings, D.1
McStay, G.2
Saleh, M.3
-
33
-
-
24044494290
-
Knockdown ofp53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis
-
Chaturvedi V, Sitailo LA, Qin JZ, et al. Knockdown ofp53 levels in human keratinocytes accelerates Mcl-1 and Bcl-x(L) reduction thereby enhancing UV-light induced apoptosis. Oncogene 2005;24:5299-312.
-
(2005)
Oncogene
, vol.24
, pp. 5299-5312
-
-
Chaturvedi, V.1
Sitailo, L.A.2
Qin, J.Z.3
-
34
-
-
34547481316
-
Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling
-
Knezevic D, Zhang W, Rochette PJ, Brash DE. Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling. Proc Natl Acad Sci U S A 2007;104:11286-91.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11286-11291
-
-
Knezevic, D.1
Zhang, W.2
Rochette, P.J.3
Brash, D.E.4
-
35
-
-
9144253200
-
-
Steinbach JP, Weller M. Apoptosis in gliomas: molecular mechanisms and therapeutic implications. J Neurooncol 2004;70:245 -54.
-
Steinbach JP, Weller M. Apoptosis in gliomas: molecular mechanisms and therapeutic implications. J Neurooncol 2004;70:245 -54.
-
-
-
-
36
-
-
0032977124
-
Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines
-
Ishii N, Maier D, Merlo A, et al. Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 1999;9:469-79.
-
(1999)
Brain Pathol
, vol.9
, pp. 469-479
-
-
Ishii, N.1
Maier, D.2
Merlo, A.3
-
37
-
-
0028873964
-
Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product
-
Tewari M, Dixit VM. Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 1995;270:3255 -60.
-
(1995)
J Biol Chem
, vol.270
, pp. 3255-3260
-
-
Tewari, M.1
Dixit, V.M.2
-
38
-
-
0033632162
-
Suppression of p53: A new approach to overcome side effects of antitumor therapy
-
Komarova EA, Gudkov AV. Suppression of p53: a new approach to overcome side effects of antitumor therapy. Biochemistry (Mosc) 2000;65:41-8.
-
(2000)
Biochemistry (Mosc)
, vol.65
, pp. 41-48
-
-
Komarova, E.A.1
Gudkov, A.V.2
-
39
-
-
0030902253
-
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells
-
Balajee AS, May A, Dianov GL, Friedberg EC, Bohr VA. Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells. Proc Natl Acad Sci U S A 1997;94:4306-11.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 4306-4311
-
-
Balajee, A.S.1
May, A.2
Dianov, G.L.3
Friedberg, E.C.4
Bohr, V.A.5
|