Sirtuins (histone deacetylases III) in the cellular response to DNA damage - Facts and hypotheses

DNA Repair

Volumn 4, Issue 11, 2005, Pages 1306-1313

  Kruszewski, Marcin ^a   Szumiel, Irena ^a  

^a INSTITUTE OF NUCLEAR CHEMISTRY AND TECHNOLOGY   (Poland)

Author keywords

Apoptosis; DNA double strand breaks; Poly(ADP ribose) polymerase

Indexed keywords

DNA; HISTONE DEACETYLASE; HISTONE DEACETYLASE 3; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SIRTUIN; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG;

ACETYLATION; APOPTOSIS; CELL TYPE; CHROMATIN STRUCTURE; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME METABOLISM; EXCISION REPAIR; FUNGAL GENE; GENE EXPRESSION REGULATION; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; STRUCTURAL HOMOLOGY;

MAMMALIA;

EID: 27544508549     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2005.06.013     Document Type: Article

References (62)

1. R.D. Kornberg, and Y. Lorch Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome Cell 98 1999 285 294
2. L. Mohrmann, and C.P. Verrijzer Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes Biochim. Biophys. Acta 1681 2005 59 73
3. M.J. Carrozza, R.T. Utley, J.L. Workman, and J. Cote The diverse functions of histone acetyltransferase complexes Trends Genet. 19 2003 321 329
4. A.J. de Ruijter, A.H. van Gennip, H.N. Caron, S. Kemp, and A.B. van Kuilenburg Histone deacetylases (HDACs): characterization of the classical HDAC family Biochem. J. 370 2003 737 749
5. S. Milutinovic, Q. Zhuang, and M. Szyf Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification J. Biol. Chem. 277 2002 20974 20978
6. W. Fischle, S. Emiliani, M.J. Hendzel, T. Nagase, N. Nomura, W. Voelter, and E. Verdin A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p J. Biol. Chem. 274 1999 11713 11720
7. C.M. Grozinger, C.A. Hassig, and S.L. Schreiber Three proteins define a class of human histone deacetylases related to yeast Hda1p Proc. Natl. Acad. Sci. U.S.A. 96 1999 4868 4873
8. E. Hu, Z. Chen, T. Fredrickson, Y. Zhu, R. Kirkpatrick, G.F. Zhang, K. Johanson, C.M. Sung, R. Liu, and J. Winkler Cloning and characterization of a novel human class I histone deacetylase that functions as a transcription repressor J. Biol. Chem. 275 2000 15254 15264
9. N.R. Bertos, A.H. Wang, and X.J. Yang Class II histone deacetylases: structure, function, and regulation Biochem. Cell Biol. 79 2001 243 252
10. J. Arts, S. De Schepper, and K. Van Emelen Histone deacetylase inhibitors: from chromatin remodeling to experimental cancer therapeutics Curr. Med. Chem. 10 2003 2343 2350
11. L. Catley, E. Weisberg, Y.T. Tai, P. Atadja, S. Remiszewski, T. Hideshima, N. Mitsiades, R. Shringarpure, R. LeBlanc, D. Chauhan, N.C. Munshi, R. Schlossman, P. Richardson, J. Griffin, and K.C. Anderson NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma Blood 102 2003 2615 2622
12. K. Fronsdal, and F. Saatcioglu Histone deacetylase inhibitors differentially mediate apoptosis in prostate cancer cells Prostate 62 2005 299 306
13. S.B. Khan, T. Maududi, K. Barton, J. Ayers, and S. Alkan Analysis of histone deacetylase inhibitor, depsipeptide (FR901228), effect on multiple myeloma Br. J. Haematol. 125 2004 156 161
14. R.W. Johnstone Histone-deacetylase inhibitors: novel drugs for the treatment of cancer Nat. Rev. Drug Discov. 1 2002 287 299
15. D.M. Vigushin, and R.C. Coombes Histone deacetylase inhibitors in cancer treatment Anticancer Drugs 13 2002 1 13
16. M. Yoshida, A. Matsuyama, Y. Komatsu, and N. Nishino From discovery to the coming generation of histone deacetylase inhibitors Curr. Med. Chem. 10 2003 2351 2358
17. J.R. Davie Inhibition of histone deacetylase activity by butyrate J. Nutr. 133 2003 2485S 2493S
18. G. Blander, and L. Guarente The Sir2 family of protein deacetylases Annu. Rev. Biochem. 73 2004 417 435
19. S.W. Buck, C.M. Gallo, and J.S. Smith Diversity in the Sir2 family of protein deacetylases J. Leukoc. Biol. 75 2004 939 950
20. M.T. Borra, M.R. Langer, J.T. Slama, and J.M. Denu Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases Biochemistry 43 2004 9877 9887
21. M.D. Jackson, M.T. Schmidt, N.J. Oppenheimer, and J.M. Denu Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases J. Biol. Chem. 278 2003 50985 50998
22. K. Zhao, R. Harshaw, X. Chai, and R. Marmorstein Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases Proc. Natl. Acad. Sci. U.S.A. 101 2004 8563 8568
23. K.J. Bitterman, R.M. Anderson, H.Y. Cohen, M. Latorre-Esteves, and D.A. Sinclair Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1 J. Biol. Chem. 277 2002 45099 45107
24. M.T. Borra, F.J. O'Neill, M.D. Jackson, B. Marshall, E. Verdin, K.R. Foltz, and J.M. Denu Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases J. Biol. Chem. 277 2002 12632 12641
25. R.M. Anderson, K.J. Bitterman, J.G. Wood, O. Medvedik, and D.A. Sinclair Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae Nature 423 2003 181 185
26. C.M. Gallo, D.L. Smith Jr., and J.S. Smith Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity Mol. Cell. Biol. 24 2004 1301 1312
27. L.K. Lewis, and M.A. Resnick Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae Mutat. Res. 451 2000 71 89
28. A. Jazayeri, A.D. McAinsh, and S.P. Jackson Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair Proc. Natl. Acad. Sci. U.S.A. 101 2004 1644 1649
29. O. Fernandez-Capetillo, and A. Nussenzweig Linking histone deacetylation with the repair of DNA breaks Proc. Natl. Acad. Sci. U.S.A. 101 2004 1427 1428
30. S.J. Boulton, A. Gartner, J. Reboul, P. Vaglio, N. Dyson, D.E. Hill, and M. Vidal Combined functional genomic maps of the C. elegans DNA damage response Science 295 2002 127 131
31. A.W. Bird, D.Y. Yu, M.G. Pray-Grant, Q. Qiu, K.E. Harmon, P.C. Megee, P.A. Grant, M.M. Smith, and M.F. Christman Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair Nature 419 2002 411 415
32. J.D. Moore, and J.E. Krebs Histone modifications and DNA double-strand break repair Biochem. Cell. Biol. 82 2004 446 452
33. Y. Aylon, B. Liefshitz, and M. Kupiec The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle EMBO J. 23 2004 4868 4875
34. J. Zhang Are poly(ADP-ribosyl)ation by PARP-1 and deacetylation by Sir2 linked? Bioessays 25 2003 808 814
35. H.Y. Cohen, S. Lavu, K.J. Bitterman, B. Hekking, T.A. Imahiyerobo, C. Miller, R. Frye, H. Ploegh, B.M. Kessler, and D.A. Sinclair Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis Mol. Cell 13 2004 627 638
36. H.Y. Cohen, C. Miller, K.J. Bitterman, N.R. Wall, B. Hekking, B. Kessler, K.T. Howitz, M. Gorospe, R. de Cabo, and D.A. Sinclair Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase Science 305 2004 390 392
37. M. Malanga, and F. Althaus DNA damage signaling through poly(ADP-robose) A. Bürkle Poly(ADP-Ribosyl)ation 2004 Landes Bioscience Georgetown, USA 484 493
38. P. Berardi, M. Russell, A. El Osta, and K. Riabowol Functional links between transcription, DNA repair and apoptosis Cell. Mol. Life Sci. 61 2004 2173 2180
39. A. Verger, and M. Crossley Chromatin modifiers in transcription and DNA repair Cell. Mol. Life Sci. 61 2004 2154 2162
40. T. Ikura, V.V. Ogryzko, M. Grigoriev, R. Groisman, J. Wang, M. Horikoshi, R. Scully, J. Qin, and Y. Nakatani Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis Cell 102 2000 463 473
41. E.J. Park, D.W. Chan, J.H. Park, M.A. Oettinger, and J. Kwon DNA-PK is activated by nucleosomes and phosphorylates H2AX within the nucleosomes in an acetylation-dependent manner Nucleic Acids Res. 31 2003 6819 6827
42. H. Lewandowska, and I. Szumiel Histone H2AX in DNA repair Nukleonika 47 2002 127 131
43. K. Camphausen, T. Scott, M. Sproull, and P.J. Tofilon Enhancement of xenograft tumor radiosensitivity by the histone deacetylase inhibitor MS-275 and correlation with histone hyperacetylation Clin. Cancer Res. 10 2004 6066 6071
44. K. Camphausen, W. Burgan, M. Cerra, K.A. Oswald, J.B. Trepel, M.J. Lee, and P.J. Tofilon Enhanced radiation-induced cell killing and prolongation of gammaH2AX foci expression by the histone deacetylase inhibitor MS-275 Cancer Res. 64 2004 316 321
45. K. Camphausen, D. Cerna, T. Scott, M. Sproull, W.E. Burgan, M.A. Cerra, H. Fine, and P.J. Tofilon Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid Int. J. Cancer 114 2005 380 386
46. M.S. Kim, M. Blake, J.H. Baek, G. Kohlhagen, Y. Pommier, and F. Carrier Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA Cancer Res. 63 2003 7291 7300
47. R.L. Cai, Y. Yan-Neale, M.A. Cueto, H. Xu, and D. Cohen HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins J. Biol. Chem. 275 2000 27909 27916
48. J.R. Davie, S.K. Samuel, V.A. Spencer, L.T. Holth, D.N. Chadee, C.P. Peltier, J.M. Sun, H.Y. Chen, and J.A. Wright Organization of chromatin in cancer cells: role of signalling pathways Biochem. Cell. Biol. 77 1999 265 275
49. S.K. Mauldin, R.C. Getts, W. Liu, and T.D. Stamato DNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex Nucleic Acids Res. 30 2002 4075 4087
50. G.S. Stein, S.K. Zaidi, C.D. Braastad, M. Montecino, A.J. van Wijnen, J.Y. Choi, J.L. Stein, J.B. Lian, and A. Javed Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair Trends Cell Biol. 13 2003 584 592
51. H.L. Cheng, R. Mostoslavsky, S. Saito, J.P. Manis, Y. Gu, P. Patel, R. Bronson, E. Appella, F.W. Alt, and K.F. Chua Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice Proc. Natl. Acad. Sci. U.S.A. 100 2003 10794 10799
52. A. Ito, Y. Kawaguchi, C.H. Lai, J.J. Kovacs, Y. Higashimoto, E. Appella, and T.P. Yao MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation EMBO J. 21 2002 6236 6245
53. M. Gostissa, T.G. Hofmann, H. Will, and G. Del Sal Regulation of p53 functions: let's meet at the nuclear bodies Curr. Opin. Cell Biol. 15 2003 351 357
54. H. Vaziri, S.K. Dessain, E.E. Ng, S.I. Imai, R.A. Frye, T.K. Pandita, L. Guarente, and R.A. Weinberg hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase Cell 107 2001 149 159
55. E. Langley, M. Pearson, M. Faretta, U.M. Bauer, R.A. Frye, S. Minucci, P.G. Pelicci, and T. Kouzarides Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence EMBO J. 21 2002 2383 2396
56. J. Luo, A.Y. Nikolaev, S. Imai, D. Chen, F. Su, A. Shiloh, L. Guarente, and W. Gu Negative control of p53 by Sir2alpha promotes cell survival under stress Cell 107 2001 137 148
57. C. Subramanian, A.W. Opipari Jr., X. Bian, V.P. Castle, and R.P. Kwok Ku70 acetylation mediates neuroblastoma cell death induced by histone deacetylase inhibitors Proc. Natl. Acad. Sci. U.S.A. 102 2005 4842 4847
58. H. You, and T.W. Mak Crosstalk between p53 and FOXO Transcription Factors Cell Cycle 4 2005 37 38
59. A. Brunet, L.B. Sweeney, J.F. Sturgill, K.F. Chua, P.L. Greer, Y. Lin, H. Tran, S.E. Ross, R. Mostoslavsky, H.Y. Cohen, L.S. Hu, H.L. Cheng, M.P. Jedrychowski, S.P. Gygi, D.A. Sinclair, F.W. Alt, and M.E. Greenberg Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015
60. M.C. Motta, N. Divecha, M. Lemieux, C. Kamel, D. Chen, W. Gu, Y. Bultsma, M. McBurney, and L. Guarente Mammalian SIRT1 represses forkhead transcription factors Cell 116 2004 551 563
61. A. van der Horst, L.G. Tertoolen, L.M. Vries-Smits, R.A. Frye, R.H. Medema, and B.M. Burgering FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1) J. Biol. Chem. 279 2004 28873 28879
62. I.R. Radford Transcription-based model for the induction of interchromosomal exchange events by ionizing irradiation in mammalian cell lines that undergo necrosis Int. J. Radiat. Biol. 78 2002 1081 1093