Synthesis of quinoidal molecules: Strategies towards bioactive compounds with an emphasis on lapachones

European Journal of Medicinal Chemistry

Volumn 69, Issue , 2013, Pages 678-700

  De Castro, Solange L ^a   Emery, Flavio S ^b   Da Silva Júnior, Eufrânio N ^c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Inst Cie Exatas Univ Fed M   (Brazil)

Author keywords

Anticancer activity; Chagas disease; Leishmaniasis; Naphthoquinones; Synthetic strategies; Lapachone

Indexed keywords

1,2,3 TRIAZOLE DERIVATIVE; 3 ALKOXY NOR BETA LAPACHONE DERIVATIVE; 3 BROMO 4 AZIDE BETA LAPACHONE; 3 SULPHONIC ACID DERIVATIVE; ALKYNE; ALPHA LAPACHONE; ALPHA LAPACHONE DERIVATIVE; AZIDE; AZULENE DERIVATIVE; BENZNIDAZOLE; BETA LAPACHONE; CHLOROQUINE; COPPER; DOXORUBICIN; FURAN DERIVATIVE; LAPACHOL; NAPHTHOQUINONE; NOR ALPHA LAPACHONE; NOR BETA LAPACHONE; NOR BETA LAPACHONE ARYLAMINO DERIVATIVE; PALLADIUM; PENTAMIDINE; PHENAZINE DERIVATIVE; PTEROCARPANQUINONE; PYRAN DERIVATIVE; QUINONE DERIVATIVE; QUINOXALINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; BIOCATALYSIS; BIOLOGICAL ACTIVITY; CELL MEMBRANE; CELL ORGANELLE; CHAGAS DISEASE; CHEMICAL MODIFICATION; CROSS COUPLING REACTION; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; LEISHMANIA; LEISHMANIASIS; LIPOPHILICITY; MALARIA; NEGLECTED DISEASE; NEOPLASM; NONHUMAN; OXIDATION REDUCTION REACTION; REVIEW; TRYPANOSOMA CRUZI; TUBERCULOSIS;

ANTICANCER ACTIVITY; CHAGAS DISEASE; LEISHMANIASIS; NAPHTHOQUINONES; SYNTHETIC STRATEGIES; Β-LAPACHONE;

ANIMALS; CELL MEMBRANE; CHAGAS DISEASE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LEISHMANIA; LEISHMANIASIS; MALARIA; NAPHTHOQUINONES; NEOPLASMS; REACTIVE OXYGEN SPECIES; TRYPANOSOMA CRUZI; TUBERCULOSIS;

EID: 84884733372     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.07.057     Document Type: Short Survey

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