New pterocarpanquinones: Synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-α modulation in human PBMC cells

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 4, 2010, Pages 1610-1616

  Netto, Chaquip D ^a   da Silva, Alcides J M ^a   Salustiano, Eduardo J S ^a   Bacelar, Thiago S ^a   Riça, Ingred G ^a   Cavalcante, Moises C M ^a   Rumjanek, Vivian M ^a   Costa, Paulo R R ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Bioreduction; Cancer; Catalytic oxa Heck reaction; Naphthoquinone; Pterocarpan; TNF modulation

Indexed keywords

ANTINEOPLASTIC AGENT; ERYTHRITOL; HYDROQUINONE; MITOMYCIN; PALLADIUM; PTEROCARPANQUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE QUINONE OXIDOREDUCTASE 1; SODIUM DITHIONITE; THIOPHENOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; ARYLATION; CANCER CELL CULTURE; CANCER RESISTANCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LEUKEMIA CELL LINE; MICHAEL ADDITION; MULTIDRUG RESISTANCE; PERIPHERAL BLOOD MONONUCLEAR CELL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MONOCYTES; PTEROCARPANS; QUINONES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 76149127986     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.12.073     Document Type: Article

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