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Volumn 10, Issue 11, 2000, Pages 1151-1154

Hepatitis C viral IRES inhibition by phenazine and phenazine-like molecules

Author keywords

[No Author keywords available]

Indexed keywords

PHENAZINE; PHENAZINE DERIVATIVE;

EID: 0342699722     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00217-1     Document Type: Article
Times cited : (58)

References (22)
  • 1
    • 0000494074 scopus 로고    scopus 로고
    • Hepatitis C: global prevalence
    • World Health Organization.
    • (a) World Health Organization. Hepatitis C: global prevalence. Weekly Epidemiological Record 1997, 10, 65.
    • (1997) Weekly Epidemiological Record , vol.10 , pp. 65
  • 17
    • 0343551808 scopus 로고    scopus 로고
    • 4 cells/well in a 96-well plate. The compounds were then added at various concentrations in a final DMSO concentration of 0.2% and incubate 24 h at 37 °C. Following the incubation the cells were washed twice in PBS. 50 μL of Luciferin lysis buffer is added and kept for 10 min in the dark. Cells were then re-suspended and 80 μL was taken on a white 96-well plate for Luciferase activity
    • 4 cells/well in a 96-well plate. The compounds were then added at various concentrations in a final DMSO concentration of 0.2% and incubate 24 h at 37 °C. Following the incubation the cells were washed twice in PBS. 50 μL of Luciferin lysis buffer is added and kept for 10 min in the dark. Cells were then re-suspended and 80 μL was taken on a white 96-well plate for Luciferase activity.
  • 19
    • 0343115858 scopus 로고    scopus 로고
    • A molecular mechanics calculation using HyperChem program suggests, in addition to the widened angle, a slight pyramidal configuration for the central nitrogen atom in structures 2 and 3
    • A molecular mechanics calculation using HyperChem program suggests, in addition to the widened angle, a slight pyramidal configuration for the central nitrogen atom in structures 2 and 3.
  • 20
    • 0342681548 scopus 로고    scopus 로고
    • note
    • +: 227. All commercial compounds showed purity 〉90% by HPLC analysis.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.