메뉴 건너뛰기




Volumn 4, Issue AUG, 2013, Pages

Biotic acts of antibiotics

Author keywords

Cancer; Cardiovascular; Inflammation; Macrolides; Neuroprotection; Respiratory; Tetracyclines; lactam

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; BETA LACTAM; CEFTRIAXONE; CEPHALOSPORIN; CLARITHROMYCIN; DOXYCYCLINE; ERYTHROMYCIN; MACROLIDE; MATRIX METALLOPROTEINASE; METHOTREXATE; MINOCYCLINE; TACROLIMUS; TELITHROMYCIN; TETRACYCLINE;

EID: 84884237650     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2013.00241     Document Type: Review
Times cited : (37)

References (213)
  • 1
    • 61349098833 scopus 로고    scopus 로고
    • Doxycycline aneurysm: improved proteolytic balance through reduced neutrophil content
    • doi: 10.1016/j.jvs.2008.09.055
    • Abdul-Hussien, H., Hanemaaijer, R., Verheijen, J. H., van Bockel, J. H., Geelkerken, R. H., and Lindeman, J. H. (2009). Doxycycline aneurysm: improved proteolytic balance through reduced neutrophil content. J. Vasc. Surg. 49, 741-749. doi: 10.1016/j.jvs.2008.09.055
    • (2009) J. Vasc. Surg. , vol.49 , pp. 741-749
    • Abdul-Hussien, H.1    Hanemaaijer, R.2    Verheijen, J.H.3    van Bockel, J.H.4    Geelkerken, R.H.5    Lindeman, J.H.6
  • 3
    • 84875759214 scopus 로고    scopus 로고
    • Sequencing ancient calcified dental plaque microbiota with dietary shifts of the Neolithic and Industrial revolutions
    • doi: 10.1038/ng.2536
    • Adler, C. J., Dobney, K., Weyrich, L. S., Kaidonis, J., Walker, A. W., Haak, W., et al. (2013). Sequencing ancient calcified dental plaque microbiota with dietary shifts of the Neolithic and Industrial revolutions. Nat. Genet. 45, 450-455. doi: 10.1038/ng.2536
    • (2013) Nat. Genet. , vol.45 , pp. 450-455
    • Adler, C.J.1    Dobney, K.2    Weyrich, L.S.3    Kaidonis, J.4    Walker, A.W.5    Haak, W.6
  • 4
    • 84880279593 scopus 로고    scopus 로고
    • Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal reinstatement of preference in mice
    • doi: 10.1007/s00213-013-3047-32013
    • Alajaji, M., Bowers, M. S., Knackstedt, L., and Damaj, M. I. (2013). Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal reinstatement of preference in mice. Psychopharmacology (Berl.) 228, 419-426. doi: 10.1007/s00213-013-3047-32013
    • (2013) Psychopharmacology (Berl.) , vol.228 , pp. 419-426
    • Alajaji, M.1    Bowers, M.S.2    Knackstedt, L.3    Damaj, M.I.4
  • 6
    • 84875524849 scopus 로고    scopus 로고
    • Effect of azithromycin maintenance exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial
    • Altenburg, J., de Graaff, C. S., Stienstra, Y., Sloos, J. H., van Haren, E. H., Koppers, R. J., et al. (2013). Effect of azithromycin maintenance exacerbations among patients with non-cystic fibrosis bronchiectasis: the BAT randomized controlled trial. JAMA 309, 1251
    • (2013) JAMA , vol.309 , pp. 1251
    • Altenburg, J.1    de Graaff, C.S.2    Stienstra, Y.3    Sloos, J.H.4    van Haren, E.H.5    Koppers, R.J.6
  • 8
    • 71249091793 scopus 로고    scopus 로고
    • The role of antibiotics and antibiotic resistance in nature
    • doi: 10.1111/j.
    • Aminov, R. I. (2009). The role of antibiotics and antibiotic resistance in nature. Environ. Microbiol. 11, 2970-2988. doi: 10.1111/j.
    • (2009) Environ. Microbiol. , vol.11 , pp. 2970-2988
    • Aminov, R.I.1
  • 9
    • 84884250538 scopus 로고    scopus 로고
    • Evolution in action: dissemination of tet(X) into pathogenic microbiota
    • doi: 10.3389/
    • Aminov, R. I. (2013). Evolution in action: dissemination of tet(X) into pathogenic microbiota. Front. Microbiol. 4:192. doi: 10.3389/
    • (2013) Front. Microbiol. , vol.4 , pp. 192
    • Aminov, R.I.1
  • 10
    • 0002078065 scopus 로고    scopus 로고
    • Advanced-generation macrolides: tissue-directed antibiotics
    • Amsden, G. W. (2001). Advanced-generation macrolides: tissue-directed antibiotics. Int. J. Antimicrob. Agents 18(Suppl. 1), S11 00410-1
    • (2001) Int. J. Antimicrob. Agents , vol.18 , Issue.SUPPL. 1
    • Amsden, G.W.1
  • 11
    • 84876315548 scopus 로고    scopus 로고
    • Learned and unlearned concepts in periodontal diagnostics: a 50-year perspective
    • Armitage, G. C. (2013). Learned and unlearned concepts in periodontal diagnostics: a 50-year perspective. Periodontol. 2000
    • (2013) Periodontol. 2000
    • Armitage, G.C.1
  • 12
    • 84880917867 scopus 로고    scopus 로고
    • Disruption of alcohol-related memories by mTORC1 Nat
    • doi: 10.1038/nn.3439
    • Barak, S., Liu, F., Hamida, S. B., Yowell, Q. V., Neasta, J., Kharazia, V., et al. (2013). Disruption of alcohol-related memories by mTORC1 Nat. Neurosci. 16, 1111-1117. doi: 10.1038/nn.3439
    • (2013) Neurosci. , vol.16 , pp. 1111-1117
    • Barak, S.1    Liu, F.2    Hamida, S.B.3    Yowell, Q.V.4    Neasta, J.5    Kharazia, V.6
  • 13
    • 84876319818 scopus 로고    scopus 로고
    • Periodontitis: a host-mediated disruption of microbial homeostasis
    • doi: 10.1111/j.1600-0757.2012.00450.x
    • Bartold, P. M., and Van Dyke, T. E. (2013). Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned 203-217. doi: 10.1111/j.1600-0757.2012.00450.x
    • (2013) Unlearning learned , pp. 203-217
    • Bartold, P.M.1    Van Dyke, T.E.2
  • 14
    • 43649099775 scopus 로고    scopus 로고
    • Posterior reversible encephalopathy syndrome AJNR Am
    • doi: 10.3174/ajnr.A0960
    • Bartynski, W. S., Tan, H. P., Boardman, J. F., Shapiro, R., and Marsh, J. W. (2008). Posterior reversible encephalopathy syndrome AJNR Am. J. Neuroradiol. 29, 924-930. doi: 10.3174/ajnr.A0960
    • (2008) J. Neuroradiol. , vol.29 , pp. 924-930
    • Bartynski, W.S.1    Tan, H.P.2    Boardman, J.F.3    Shapiro, R.4    Marsh, J.W.5
  • 15
    • 54049133777 scopus 로고    scopus 로고
    • Tacrolimus (FK506) for induction of remission in refractory ulcerative Syst
    • doi: 10.1002/14651858.CD007216
    • Baumgart, D. C., MacDonald, J. K., and Feagan, B. G. (2008). Tacrolimus (FK506) for induction of remission in refractory ulcerative Syst. Rev. 16, CD007216. doi: 10.1002/14651858.CD007216
    • (2008) Rev. , vol.16
    • Baumgart, D.C.1    MacDonald, J.K.2    Feagan, B.G.3
  • 16
    • 33646582645 scopus 로고    scopus 로고
    • Tacrolimus is safe and effective in patients steroid-dependent inflammatory bowel disease - a long-term follow-up
    • doi: 10.1111/j.1572
    • Baumgart, D. C., Pintoffl, J. P., Sturm, A., Wiedenmann, B., and Dignass, A. U. (2006). Tacrolimus is safe and effective in patients steroid-dependent inflammatory bowel disease - a long-term follow-up. Am. J. Gastroenterol. 101, 1048-1056. doi: 10.1111/j.1572
    • (2006) Am. J. Gastroenterol. , vol.101 , pp. 1048-1056
    • Baumgart, D.C.1    Pintoffl, J.P.2    Sturm, A.3    Wiedenmann, B.4    Dignass, A.U.5
  • 17
    • 84876243023 scopus 로고    scopus 로고
    • Design and initial results of a multi ceftriaxone in amyotrophic lateral sclerosis
    • doi: 10.1371/journal.pone.0061177
    • Berry, J. D., Shefner, J. M., Conwit, R., Schoenfeld, D., Keroack, M., Felsenstein, D., et al. (2013). Design and initial results of a multi ceftriaxone in amyotrophic lateral sclerosis. PLoS ONE 8:e61177. doi: 10.1371/journal.pone.0061177
    • (2013) PLoS ONE , vol.8
    • Berry, J.D.1    Shefner, J.M.2    Conwit, R.3    Schoenfeld, D.4    Keroack, M.5    Felsenstein, D.6
  • 19
    • 62149089881 scopus 로고    scopus 로고
    • Minocycline promotes dendritic spine maturation performance in the fragile X mouse model
    • doi: 10.1136/jmg.2008.061796
    • Bilousova, T. V., Dansie, L., Ngo, M., Aye, J., Charles, J. R., Ethell, D. W., et al. (2009). Minocycline promotes dendritic spine maturation performance in the fragile X mouse model. J. Med. Genet. 46, 94-102. doi: 10.1136/jmg.2008.061796
    • (2009) J. Med. Genet. , vol.46 , pp. 94-102
    • Bilousova, T.V.1    Dansie, L.2    Ngo, M.3    Aye, J.4    Charles, J.R.5    Ethell, D.W.6
  • 20
    • 77950337693 scopus 로고    scopus 로고
    • Long-term azithromycin use in patients with disease and tracheostomy
    • doi: 10.1016/j.pupt.2009.12.002
    • Blasi, F., Bonardi, D., Aliberti, S., Tarsia, P., Confalonieri, M., Amir, O., et al. (2010). Long-term azithromycin use in patients with disease and tracheostomy. Pulm. Pharmacol. Ther. 23, 200-207. doi: 10.1016/j.pupt.2009.12.002
    • (2010) Pulm. Pharmacol. Ther. , vol.23 , pp. 200-207
    • Blasi, F.1    Bonardi, D.2    Aliberti, S.3    Tarsia, P.4    Confalonieri, M.5    Amir, O.6
  • 21
    • 84863831095 scopus 로고    scopus 로고
    • N'-substitutednovel anti-inflammatory macrolides without antimicrobial activity
    • doi: 10.1021/jm300356u
    • Bosnar, M., Kragol, G., Koštrun, S., Vujasinoviæ, I., Bošnjak, B., Bencetiæ Mihaljeviæ, V., et al. (2012). N'-substitutednovel anti-inflammatory macrolides without antimicrobial activity. J. Med. Chem. 55, 6111-6123. doi: 10.1021/jm300356u
    • (2012) J. Med. Chem. , vol.55 , pp. 6111-6123
    • Bosnar, M.1    Kragol, G.2    Koštrun, S.3    Vujasinoviæ, I.4    Bošnjak, B.5    Bencetiæ Mihaljeviæ, V.6
  • 22
    • 0028360374 scopus 로고
    • A mammalian protein targeted by G1 complex
    • doi: 10.1038/369756a0
    • Brown, E. J., Albers, M. W., Shin, T. B., Ichikawa, K., Keith, C. T., Lane, W. S., et al. (1994). A mammalian protein targeted by G1 complex. Nature 369, 756-758. doi: 10.1038/369756a0
    • (1994) Nature , vol.369 , pp. 756-758
    • Brown, E.J.1    Albers, M.W.2    Shin, T.B.3    Ichikawa, K.4    Keith, C.T.5    Lane, W.S.6
  • 23
    • 0014666943 scopus 로고
    • Antimicrobial activity of some marine sponges
    • doi: 10.1038/222983a0
    • Burkholder, P. R., and Ruetzler, K. (1969). Antimicrobial activity of some marine sponges. Nature 222, 983-984. doi: 10.1038/222983a0
    • (1969) Nature , vol.222 , pp. 983-984
    • Burkholder, P.R.1    Ruetzler, K.2
  • 24
    • 0036841685 scopus 로고    scopus 로고
    • The growth response of Escherichia coli catecholamine drugs requires a functional enterobactin biosynthesis and uptake system
    • doi:
    • Burton, C. L., Chhabra, S. R., Swift, S., Baldwin, T. J., Withers, H., Hill, S. J., et al. (2002). The growth response of Escherichia coli catecholamine drugs requires a functional enterobactin biosynthesis and uptake system. Infect. Immun. 70, 5913-5923. doi:
    • (2002) Infect. Immun. , vol.70 , pp. 5913-5923
    • Burton, C.L.1    Chhabra, S.R.2    Swift, S.3    Baldwin, T.J.4    Withers, H.5    Hill, S.J.6
  • 25
    • 0030841343 scopus 로고    scopus 로고
    • Conformational disease
    • doi: 10.1016/S0140-6736(97)02073
    • Carrell, R. W., and Lomas, D. A. (1997). Conformational disease. Lancet 350, 134-138. doi: 10.1016/S0140-6736(97)02073
    • (1997) Lancet , vol.350 , pp. 134-138
    • Carrell, R.W.1    Lomas, D.A.2
  • 26
    • 84860146607 scopus 로고    scopus 로고
    • Results of a phase II placeboacute spinal cord injury
    • doi: 10.1093/brain/aws072
    • Casha, S., Zygun, D., McGowan, M. D., Bains, I., Yong, V. W., and Hurlbert, R. J. (2012). Results of a phase II placeboacute spinal cord injury. Brain 135, 1224-1236. doi: 10.1093/brain/aws072
    • (2012) Brain , vol.135 , pp. 1224-1236
    • Casha, S.1    Zygun, D.2    McGowan, M.D.3    Bains, I.4    Yong, V.W.5    Hurlbert, R.J.6
  • 27
    • 80054110244 scopus 로고    scopus 로고
    • Matrix metalloproteinases: targets for doxycycline to prevent the vascular Pharmacol
    • doi: 10.1016/j.phrs.2011.04.002
    • Castro, M. M., Tanus-Santos, J. E., and Gerlach, R. F. (2011). Matrix metalloproteinases: targets for doxycycline to prevent the vascular Pharmacol. Res. 64, 567-572. doi: 10.1016/j.phrs.2011.04.002
    • (2011) Res. , vol.64 , pp. 567-572
    • Castro, M.M.1    Tanus-Santos, J.E.2    Gerlach, R.F.3
  • 30
    • 0033912716 scopus 로고    scopus 로고
    • Minocycline inhibits caspase-1 and caspase transgenic mouse model of Huntington disease
    • doi: 10.1038/80538
    • Chen, M., Ona, V. O., Li, M., Ferrante, R. J., Fink, K. B., Zhu, S., et al. (2000). Minocycline inhibits caspase-1 and caspase transgenic mouse model of Huntington disease. Nat. Med. 6:797-801. doi: 10.1038/80538
    • (2000) Nat. Med. , vol.6 , pp. 797-801
    • Chen, M.1    Ona, V.O.2    Li, M.3    Ferrante, R.J.4    Fink, K.B.5    Zhu, S.6
  • 32
    • 35348819417 scopus 로고    scopus 로고
    • Minocycline attenuates neuronal cell death and improves Alzheimer's disease models
    • doi: 10.1038/sj.npp.1301377
    • Choi, Y., Kim, H. S., Shin, K. Y., Kim, E. M., Kim, M., Kim, H. S., et al. (2007). Minocycline attenuates neuronal cell death and improves Alzheimer's disease models. Neuropsychopharmacology 32, 2393-2404. doi: 10.1038/sj.npp.1301377
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2393-2404
    • Choi, Y.1    Kim, H.S.2    Shin, K.Y.3    Kim, E.M.4    Kim, M.5    Kim, H.S.6
  • 33
    • 33845932770 scopus 로고    scopus 로고
    • Pharmacological induction of ischemic tolerance by glutamate upregulation
    • doi: 10.1161/01.STR.0000252091.36912.65
    • Chu, K., Lee, S. T., Sinn, D. I., Ko, S. Y., Kim, E. H., Kim, J. M., et al. (2007). Pharmacological induction of ischemic tolerance by glutamate upregulation. Stroke 38, 177-182. doi: 10.1161/01.STR.0000252091.36912.65
    • (2007) Stroke , vol.38 , pp. 177-182
    • Chu, K.1    Lee, S.T.2    Sinn, D.I.3    Ko, S.Y.4    Kim, E.H.5    Kim, J.M.6
  • 34
    • 33745881353 scopus 로고    scopus 로고
    • The QseC sensor kinase: a bacterial adrenergic receptor
    • doi: 10.1073/pnas.0604343103
    • Clarke, M. B., Hughes, D. T., Zhu, C., Boedeker, E. C., and Sperandio, V. (2006). The QseC sensor kinase: a bacterial adrenergic receptor. U.S.A. 103, 10420-10425. doi: 10.1073/pnas.0604343103
    • (2006) U.S.A. , vol.103 , pp. 10420-10425
    • Clarke, M.B.1    Hughes, D.T.2    Zhu, C.3    Boedeker, E.C.4    Sperandio, V.5
  • 35
    • 36248931517 scopus 로고    scopus 로고
    • Nonimmunosuppressive effects of mammalian target of rapamycin inhibitors
    • 10.1016/j.trre.2007.09.003
    • Cruzado, J. M. (2008). Nonimmunosuppressive effects of mammalian target of rapamycin inhibitors. Transplant. Rev. (Orlando). 10.1016/j.trre.2007.09.003
    • (2008) Transplant. Rev. (Orlando)
    • Cruzado, J.M.1
  • 36
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • doi: 10.1016/S0301-0082(00)00067-8
    • Danbolt, N. C. (2001). Glutamate uptake. Prog. Neurobiol. 65, 1-105. doi: 10.1016/S0301-0082(00)00067-8
    • (2001) Prog. Neurobiol. , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 37
    • 80052899871 scopus 로고    scopus 로고
    • Effect of doxycycline in patients of moderate obstructive pulmonary disease with stable symptoms
    • doi: 10.4103/1817-1737.84777
    • Dalvi, P. S., Singh, A., Trivedi, H. R., Ghanchi, F. D., Parmar, D. M., and Mistry, S. D. (2011). Effect of doxycycline in patients of moderate obstructive pulmonary disease with stable symptoms. Ann. Thorac. Med. 6, 221-226. doi: 10.4103/1817-1737.84777
    • (2011) Ann. Thorac. Med. , vol.6 , pp. 221-226
    • Dalvi, P.S.1    Singh, A.2    Trivedi, H.R.3    Ghanchi, F.D.4    Parmar, D.M.5    Mistry, S.D.6
  • 38
    • 33748698411 scopus 로고    scopus 로고
    • The world of subinhibitory antibiotic concentrations
    • 10.1016/j.mib.2006.08.006
    • Davies, J., Spiegelman, G. B., and Yim, G. (2006). The world of subinhibitory antibiotic concentrations. Curr. Opin. Microbiol. 10.1016/j.mib.2006.08.006
    • (2006) Curr. Opin. Microbiol.
    • Davies, J.1    Spiegelman, G.B.2    Yim, G.3
  • 40
    • 34548242388 scopus 로고    scopus 로고
    • Recently approved systemic therapies for acne vulgaris and rosacea
    • Del Rosso, J. Q. (2007). Recently approved systemic therapies for acne vulgaris and rosacea. Cutis 80, 113-120.
    • (2007) Cutis , vol.80 , pp. 113-120
    • Del Rosso, J.Q.1
  • 41
    • 16644362676 scopus 로고    scopus 로고
    • Calf antibiotic and sulfonamide test (CAST) for screening antibiotic calf carcasses
    • Dey, B. P., Reamer, R. P., Thaker, N. H., and Thaler, A. M. (2005). Calf antibiotic and sulfonamide test (CAST) for screening antibiotic calf carcasses. J. AOAC Int. 88, 440-446.
    • (2005) J. AOAC Int. , vol.88 , pp. 440-446
    • Dey, B.P.1    Reamer, R.P.2    Thaker, N.H.3    Thaler, A.M.4
  • 42
    • 33645454133 scopus 로고    scopus 로고
    • Randomized phase II trial of matrix metalloproteinase related Kaposi's sarcoma: an AIDS Malignancy Consortium Study
    • doi: 10.1200/JCO.2005.04.2614
    • Dezube, B. J., Krown, S. E., Lee, J. Y., Bauer, K. S., and Aboulafia, D. M. (2006). Randomized phase II trial of matrix metalloproteinase related Kaposi's sarcoma: an AIDS Malignancy Consortium Study. J. Clin. Oncol. 24, 1389-1394. doi: 10.1200/JCO.2005.04.2614
    • (2006) J. Clin. Oncol. , vol.24 , pp. 1389-1394
    • Dezube, B.J.1    Krown, S.E.2    Lee, J.Y.3    Bauer, K.S.4    Aboulafia, D.M.5
  • 43
    • 75749146196 scopus 로고    scopus 로고
    • Minocycline 1-year therapy in multiple symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial)
    • doi: 10.1002/mds.22732
    • Dodel, R., Spottke, A., Gerhard, A., Reuss, A., Reinecker, S., Schimke, N., et al. (2010). Minocycline 1-year therapy in multiple symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Mov. Disord. 25, 97-107. doi: 10.1002/mds.22732
    • (2010) Mov. Disord. , vol.25 , pp. 97-107
    • Dodel, R.1    Spottke, A.2    Gerhard, A.3    Reuss, A.4    Reinecker, S.5    Schimke, N.6
  • 45
    • 0035807904 scopus 로고    scopus 로고
    • Minocycline prevents nigrostriatal dopaminergic neurodegeneration Parkinson's disease
    • doi: 10.1073/pnas.251341998
    • Du, Y., Ma, Z., Lin, S., Dodel, R. C., Gao, F., Bales, K. R., et al. (2001). Minocycline prevents nigrostriatal dopaminergic neurodegeneration Parkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 98, 14669-14674. doi: 10.1073/pnas.251341998
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 14669-14674
    • Du, Y.1    Ma, Z.2    Lin, S.3    Dodel, R.C.4    Gao, F.5    Bales, K.R.6
  • 48
    • 80054123641 scopus 로고    scopus 로고
    • The non-antibiotic properties of tetracyclines: clinical potential in ophthalmic disease
    • 10.1016/j.phrs.2011.06.013
    • Federici, T. J. (2011). The non-antibiotic properties of tetracyclines: clinical potential in ophthalmic disease. Pharmacol. Res. 10.1016/j.phrs.2011.06.013
    • (2011) Pharmacol. Res.
    • Federici, T.J.1
  • 49
    • 82455206282 scopus 로고    scopus 로고
    • Increased intestinal permeability alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease
    • doi: 10.1371/journal.
    • Forsyth, C. B., Shannon, K. M., Kordower, J. H., Voigt, R. M., Shaikh, M., Jaglin, J. A., et al. (2011). Increased intestinal permeability alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. PLoS ONE 6:e28032. doi: 10.1371/journal.
    • (2011) PLoS ONE , vol.6
    • Forsyth, C.B.1    Shannon, K.M.2    Kordower, J.H.3    Voigt, R.M.4    Shaikh, M.5    Jaglin, J.A.6
  • 50
    • 0026018690 scopus 로고
    • Suppression of human neutrophil functions by tetracyclines
    • 0765.1991.tb01626.x
    • Gabler, W. L., and Creamer, H. R. (1991). Suppression of human neutrophil functions by tetracyclines. J. Periodontal Res. 0765.1991.tb01626.x
    • (1991) J. Periodontal Res.
    • Gabler, W.L.1    Creamer, H.R.2
  • 51
    • 84874489318 scopus 로고    scopus 로고
    • Intestinal dysbacteriosis induces changes of T lymphocyte subpopulations and orients the immune response towards humoral immunity
    • doi: 10.1186/1757-4749-4-19
    • Gao, F., Li, M., Liu, Y., Gao, C., Wen, S., and Tang, L. (2012). Intestinal dysbacteriosis induces changes of T lymphocyte subpopulations and orients the immune response towards humoral immunity. Gut Pathog. 4, 19. doi: 10.1186/1757-4749-4-19
    • (2012) Gut Pathog. , vol.4 , pp. 19
    • Gao, F.1    Li, M.2    Liu, Y.3    Gao, C.4    Wen, S.5    Tang, L.6
  • 53
    • 84926080707 scopus 로고    scopus 로고
    • Phototoxic and photoallergic cutaneous drug reactions
    • Glatz, M., and Hofbauer, G. F. (2012). Phototoxic and photoallergic cutaneous drug reactions. Chem. Immunol. Allergy
    • (2012) Chem. Immunol. Allergy
    • Glatz, M.1    Hofbauer, G.F.2
  • 55
    • 79251612602 scopus 로고    scopus 로고
    • Introduction and background
    • doi: 10.1016/j.phrs.2010.10.003
    • Golub, L. M. (2011). Introduction and background. Pharmacol. Res. 63, 99-101. doi: 10.1016/j.phrs.2010.10.003
    • (2011) Pharmacol. Res. , vol.63 , pp. 99-101
    • Golub, L.M.1
  • 56
    • 0021029655 scopus 로고
    • Minocycline reduces gingival collagenolytic Preliminary observations and a proposed new mechanism of action
    • doi: 10.1111/j.1600
    • Golub, L. M., Lee, H. M., Lehrer, G., Nemiroff, A., McNamara, T. F., Kaplan, R., et al. (1983). Minocycline reduces gingival collagenolytic Preliminary observations and a proposed new mechanism of action. J. Periodontal Res. 18, 516-526. doi: 10.1111/j.1600
    • (1983) J. Periodontal Res. , vol.18 , pp. 516-526
    • Golub, L.M.1    Lee, H.M.2    Lehrer, G.3    Nemiroff, A.4    McNamara, T.F.5    Kaplan, R.6
  • 57
    • 0023245356 scopus 로고
    • A non-antibacterial chemically mammalian collagenase activity
    • doi: 10.1177/00220345870660080401
    • Golub, L. M., McNamara, T. F., D'Angelo, G., Greenwald, R. A., and Ramamurthy, N. S. (1987). A non-antibacterial chemically mammalian collagenase activity. J. Dent. Res. 66, 1310-1314. doi: 10.1177/00220345870660080401
    • (1987) J. Dent. Res. , vol.66 , pp. 1310-1314
    • Golub, L.M.1    McNamara, T.F.2    D'Angelo, G.3    Greenwald, R.A.4    Ramamurthy, N.S.5
  • 60
    • 36148960127 scopus 로고    scopus 로고
    • Efficacy of minocycline in patients sclerosis: a phase III randomised trial
    • doi: 10.1016/S1474-4422(07)70270-3
    • Gordon, P. H., Moore, D. H., Miller, R. G., Florence, J. M., Verheijde, J. L., Doorish, C., et al. (2007). Efficacy of minocycline in patients sclerosis: a phase III randomised trial. Lancet Neurol. 6, 1045-1053. doi: 10.1016/S1474-4422(07)70270-3
    • (2007) Lancet Neurol. , vol.6 , pp. 1045-1053
    • Gordon, P.H.1    Moore, D.H.2    Miller, R.G.3    Florence, J.M.4    Verheijde, J.L.5    Doorish, C.6
  • 61
    • 33846646075 scopus 로고    scopus 로고
    • Helix-loop-helix protein p8, a transcriptional regulator required for cardiac fibroblast matrix metalloprotease induction
    • doi: 10.1128/MCB.00996-06
    • Goruppi, S., Patten, R. D., Force, T., and Kyriakis, J. M. (2007). Helix-loop-helix protein p8, a transcriptional regulator required for cardiac fibroblast matrix metalloprotease induction. Mol. Cell. Biol. 27, 993-1006. doi: 10.1128/MCB.00996-06
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 993-1006
    • Goruppi, S.1    Patten, R.D.2    Force, T.3    Kyriakis, J.M.4
  • 62
    • 80054111619 scopus 로고    scopus 로고
    • The road forward: the scientific basis for tetracycline treatment of arthritic disorders
    • 10.1016/j.phrs.2011.06.010
    • Greenwald, R. A. (2011). The road forward: the scientific basis for tetracycline treatment of arthritic disorders. Pharmacol. Res. 10.1016/j.phrs.2011.06.010
    • (2011) Pharmacol. Res.
    • Greenwald, R.A.1
  • 64
    • 80054095409 scopus 로고    scopus 로고
    • Non-antibacterial tetracyclines modulate mediators atherosclerotic cardiovascular disease: a mechanistic link between local and systemic inflammation
    • Gu, Y., Lee, H. M., Sorsa, T., Salminen, A., Ryan, M. E., Slepian, M. J., et al. (2011). Non-antibacterial tetracyclines modulate mediators atherosclerotic cardiovascular disease: a mechanistic link between local and systemic inflammation. Pharmacol. Res.
    • (2011) Pharmacol. Res.
    • Gu, Y.1    Lee, H.M.2    Sorsa, T.3    Salminen, A.4    Ryan, M.E.5    Slepian, M.J.6
  • 66
    • 79955728789 scopus 로고    scopus 로고
    • Role of GLT-1 transporter activation in prevention of cannabinoid tolerance by the mice
    • doi: 10.1016/j.pbb.2011.04.012
    • Gunduz, O., Oltulu, C., and Ulugol, A. (2011). Role of GLT-1 transporter activation in prevention of cannabinoid tolerance by the mice. Pharmacol. Biochem. Behav. 99, 100-103. doi: 10.1016/j.pbb.2011.04.012
    • (2011) Pharmacol. Biochem. Behav. , vol.99 , pp. 100-103
    • Gunduz, O.1    Oltulu, C.2    Ulugol, A.3
  • 68
    • 84875597555 scopus 로고    scopus 로고
    • Tacrolimus-associated posterior reversible syndrome in hematopoietic allogeneic stem cell transplantation
    • doi: 10.1002/ajh.23402
    • Hammerstrom, A. E., Howell, J., Gulbis, A., Rondon, G., Champlin, R. E., and Popat, U. (2013). Tacrolimus-associated posterior reversible syndrome in hematopoietic allogeneic stem cell transplantation. Am. J. Hematol. 88, 301-305. doi: 10.1002/ajh.23402
    • (2013) Am. J. Hematol. , vol.88 , pp. 301-305
    • Hammerstrom, A.E.1    Howell, J.2    Gulbis, A.3    Rondon, G.4    Champlin, R.E.5    Popat, U.6
  • 69
    • 15444347160 scopus 로고    scopus 로고
    • Matrix metalloproteinase-8 is expressed fibroblasts and endothelial cells Regulation by tumor necrosis factor-alpha and doxycycline
    • Hanemaaijer, R., Sorsa, T., Konttinen, Y. T., Ding, Y., Sutinen, M., Visser, H., et al. (1997). Matrix metalloproteinase-8 is expressed fibroblasts and endothelial cells. Regulation by tumor necrosis factor-alpha and doxycycline. J. Biol. Chem. 272, 31504
    • (1997) J. Biol. Chem. , vol.272 , pp. 31504
    • Hanemaaijer, R.1    Sorsa, T.2    Konttinen, Y.T.3    Ding, Y.4    Sutinen, M.5    Visser, H.6
  • 70
    • 84881251933 scopus 로고    scopus 로고
    • Microglia during development and aging
    • doi: 10.1016/j.pharmthera.2013.04.013 [Epub ahead
    • Harry, G. J. (2013). Microglia during development and aging. Pharmacol. Ther. doi: 10.1016/j.pharmthera.2013.04.013 [Epub ahead
    • (2013) Pharmacol. Ther
    • Harry, G.J.1
  • 72
    • 77950586407 scopus 로고    scopus 로고
    • Early treatment with clarithromycin attenuates myocarditis via inhibition of matrix metalloproteinase activity
    • doi: 10.1136/hrt.2009.188094
    • Hishikari, K., Watanabe, R., Ogawa, M., Suzuki, J., Masumura, M., Shimizu, T., et al. (2010). Early treatment with clarithromycin attenuates myocarditis via inhibition of matrix metalloproteinase activity. Heart 96, 523-527. doi: 10.1136/hrt.2009.188094
    • (2010) Heart , vol.96 , pp. 523-527
    • Hishikari, K.1    Watanabe, R.2    Ogawa, M.3    Suzuki, J.4    Masumura, M.5    Shimizu, T.6
  • 74
    • 72849130312 scopus 로고    scopus 로고
    • PRES (posterior reversible encephalopathy syndrome), therapy
    • doi: 10.1007/s10140-008-0782-6
    • Hodnett, P., Coyle, J., O'Regan, K., Maher, M. M., and Fanning, N. (2009). PRES (posterior reversible encephalopathy syndrome), therapy. Emerg. Radiol. 16, 493-496. doi: 10.1007/s10140-008-0782-6
    • (2009) Emerg. Radiol. , vol.16 , pp. 493-496
    • Hodnett, P.1    Coyle, J.2    O'Regan, K.3    Maher, M.M.4    Fanning, N.5
  • 76
    • 84873435354 scopus 로고    scopus 로고
    • Immunopathogenesis of chronic obstructive pulmonary disease
    • 10.1097/MCP.0b013e32835cfff5
    • Holloway, R. A., and Donnelly, L. E. (2013). Immunopathogenesis of chronic obstructive pulmonary disease. Curr. Opin. Pulm. Med. 10.1097/MCP.0b013e32835cfff5
    • (2013) Curr. Opin. Pulm. Med.
    • Holloway, R.A.1    Donnelly, L.E.2
  • 77
    • 84861213713 scopus 로고    scopus 로고
    • Drugs of last resort? The use of polymyxins Veterans Affairs medical centers, 2005-2010
    • doi: 10.1371/journal.pone.0036649
    • Huttner, B., Jones, M., Rubin, M. A., Neuhauser, M. M., Gundlapalli, A., and Samore, M. (2012). Drugs of last resort? The use of polymyxins Veterans Affairs medical centers, 2005-2010. PLoS ONE 7:e36649. doi: 10.1371/journal.pone.0036649
    • (2012) PLoS ONE , vol.7
    • Huttner, B.1    Jones, M.2    Rubin, M.A.3    Neuhauser, M.M.4    Gundlapalli, A.5    Samore, M.6
  • 78
  • 79
    • 84901438390 scopus 로고    scopus 로고
    • Minocycline improves postoperative cognitive impairment astrocytic activation
    • doi: 10.1097/WNR.0b013e3283629195 [Epub ahead of print].
    • Jin, W. J., Feng, S. W., Feng, Z., Lu, S. M., Qi, T., and Qian, Y. N. (2013). Minocycline improves postoperative cognitive impairment astrocytic activation. Neuroreport doi: 10.1097/WNR.0b013e3283629195 [Epub ahead of print].
    • (2013) Neuroreport
    • Jin, W.J.1    Feng, S.W.2    Feng, Z.3    Lu, S.M.4    Qi, T.5    Qian, Y.N.6
  • 80
    • 80052848837 scopus 로고    scopus 로고
    • Effect of tetracyclines on IgE allergic responses and asthma
    • Allergy Drug 10.2174/187221311797264919
    • Joks, R., and Durkin, H. G. (2011). Effect of tetracyclines on IgE allergic responses and asthma. Recent Pat. Inflamm. Allergy Drug 10.2174/187221311797264919
    • (2011) Recent Pat. Inflamm.
    • Joks, R.1    Durkin, H.G.2
  • 81
    • 0029875811 scopus 로고    scopus 로고
    • Transcriptional downregulation of stromelysin by tetracycline
    • 1097-4644(19960301)60:3
    • Jonat, C., Chung, F. Z., and Baragi, V. M. (1996). Transcriptional downregulation of stromelysin by tetracycline. J. Cell. Biochem. 1097-4644(19960301)60:3
    • (1996) J. Cell. Biochem.
    • Jonat, C.1    Chung, F.Z.2    Baragi, V.M.3
  • 83
    • 55249116027 scopus 로고    scopus 로고
    • Adrenaline modulates the global Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses
    • doi: 10.1186/
    • Karavolos, M. H., Spencer, H., Bulmer, D. M., Thompson, A., Winzer, K., Williams, P., et al. (2008). Adrenaline modulates the global Salmonella revealing a role in the antimicrobial peptide and oxidative stress resistance responses. BMC Genomics 9:458. doi: 10.1186/
    • (2008) BMC Genomics , vol.9 , pp. 458
    • Karavolos, M.H.1    Spencer, H.2    Bulmer, D.M.3    Thompson, A.4    Winzer, K.5    Williams, P.6
  • 84
    • 84873057823 scopus 로고    scopus 로고
    • Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop systems
    • doi: 10.1111/mmi.12110
    • Karavolos, M. H., Winzer, K., Williams, P., and Khan, C. M. (2013). Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop systems. Mol. Microbiol. 87, 455-465. doi: 10.1111/mmi.12110
    • (2013) Mol. Microbiol. , vol.87 , pp. 455-465
    • Karavolos, M.H.1    Winzer, K.2    Williams, P.3    Khan, C.M.4
  • 85
    • 84863746468 scopus 로고    scopus 로고
    • Minocycline modulates human social decision microglia on personality-oriented social behaviours
    • doi: 10.1371/journal.pone.0040461
    • Kato, T. A., Watabe, M., Tsuboi, S., Ishikawa, K., Hashiya, K., Monji, A., et al. (2012). Minocycline modulates human social decision microglia on personality-oriented social behaviours. PLoS ONE 7:e40461. doi: 10.1371/journal.pone.0040461
    • (2012) PLoS ONE , vol.7
    • Kato, T.A.1    Watabe, M.2    Tsuboi, S.3    Ishikawa, K.4    Hashiya, K.5    Monji, A.6
  • 86
    • 0023245677 scopus 로고
    • FK-506, a novel immunosuppressant isolated Fermentation, isolation, and physico-chemical and biological characteristics
    • doi: 10.7164/antibiotics.
    • Kino, T., Hatanaka, H., Hashimoto, M., Nishiyama, M., Goto, T., Okuhara, M., et al. (1987). FK-506, a novel immunosuppressant isolated Fermentation, isolation, and physico-chemical and biological characteristics. J. Antibiot. (Tokyo) 40, 1249-1255. doi: 10.7164/antibiotics.
    • (1987) J. Antibiot. (Tokyo) , vol.40 , pp. 1249-1255
    • Kino, T.1    Hatanaka, H.2    Hashimoto, M.3    Nishiyama, M.4    Goto, T.5    Okuhara, M.6
  • 88
    • 84875413952 scopus 로고    scopus 로고
    • A novel macrolide solithromycin exerts superior NF-ΚB inhibition
    • doi: 10.1124/jpet.112.200733
    • Kobayashi, Y., Wada, H., Rossios, C., Takagi, D., Higaki, M., Mikura, S., et al. (2013). A novel macrolide solithromycin exerts superior NF-ΚB inhibition. J. Pharmacol. Exp. Ther. 345, 76-84. doi: 10.1124/jpet.112.200733
    • (2013) J. Pharmacol. Exp. Ther. , vol.345 , pp. 76-84
    • Kobayashi, Y.1    Wada, H.2    Rossios, C.3    Takagi, D.4    Higaki, M.5    Mikura, S.6
  • 90
    • 23244453399 scopus 로고    scopus 로고
    • Antioxidant properties of minocycline: oxidative stress assay and direct radical-scavenging activity
    • doi: 10.1111/j.1471-4159.2005.03219.x
    • Kraus, R. L., Pasieczny, R., Lariosa-Willingham, K., Turner, M. S., Jiang, A., and Trauger, J. W. (2005). Antioxidant properties of minocycline: oxidative stress assay and direct radical-scavenging activity. J. Neurochem. 94, 819-827. doi: 10.1111/j.1471-4159.2005.03219.x
    • (2005) J. Neurochem. , vol.94 , pp. 819-827
    • Kraus, R.L.1    Pasieczny, R.2    Lariosa-Willingham, K.3    Turner, M.S.4    Jiang, A.5    Trauger, J.W.6
  • 95
    • 66049129630 scopus 로고    scopus 로고
    • Marine sponges: potential sources of new antimicrobial drugs
    • 10.2174/138920109787048625
    • Laport, M. S., Santos, O. C., and Muricy, G. (2009). Marine sponges: potential sources of new antimicrobial drugs. Curr. Pharm. Biotechnol. 10.2174/138920109787048625
    • (2009) Curr. Pharm. Biotechnol.
    • Laport, M.S.1    Santos, O.C.2    Muricy, G.3
  • 96
    • 17044417657 scopus 로고    scopus 로고
    • Minocycline attenuates mechanical proinflammatory cytokine expression in rat models of pain facilitation
    • doi: 10.1016/j.pain.2005.02.009
    • Ledeboer, A., Sloane, E. M., Milligan, E. D., Frank, M. G., Mahony, J. H., Maier, S. F., et al. (2005). Minocycline attenuates mechanical proinflammatory cytokine expression in rat models of pain facilitation. Pain 115, 71-83. doi: 10.1016/j.pain.2005.02.009
    • (2005) Pain , vol.115 , pp. 71-83
    • Ledeboer, A.1    Sloane, E.M.2    Milligan, E.D.3    Frank, M.G.4    Mahony, J.H.5    Maier, S.F.6
  • 97
    • 47549095557 scopus 로고    scopus 로고
    • Effects of telithromycin in in vitro and in vivo models of lipopolysaccharide inflammation
    • doi: 10.1378/chest.07-3056
    • Leiva, M., Ruiz-Bravo, A., and Jiménez-Valera, M. (2008a). Effects of telithromycin in in vitro and in vivo models of lipopolysaccharide inflammation. Chest 134, 20-29. doi: 10.1378/chest.07-3056
    • (2008) Chest , vol.134 , pp. 20-29
    • Leiva, M.1    Ruiz-Bravo, A.2    Jiménez-Valera, M.3
  • 98
    • 48449103341 scopus 로고    scopus 로고
    • Telithromycin inhibits the production of proinflammatory NF-kappaB in in vitro-stimulated murine cells
    • doi: 10.1111/j.1574-695X.2008.00424.
    • Leiva, M., Ruiz-Bravo, A., Moreno, E., and Jiménez-Valera, M. (2008b). Telithromycin inhibits the production of proinflammatory NF-kappaB in in vitro-stimulated murine cells. FEMS Immunol. Med. Microbiol. 53, 343-350. doi: 10.1111/j.1574-695X.2008.00424.
    • (2008) FEMS Immunol. Med. Microbiol. , vol.53 , pp. 343-350
    • Leiva, M.1    Ruiz-Bravo, A.2    Moreno, E.3    Jiménez-Valera, M.4
  • 99
    • 77649112679 scopus 로고    scopus 로고
    • A double-blind, randomized study of negative and cognitive symptoms in early-phase schizophrenia
    • doi: 10.4088/JCP.08m04666yel
    • Levkovitz, Y., Mendlovich, S., Riwkes, S., Braw, Y., Levkovitch-Verbin, H., Gal, G., et al. (2010). A double-blind, randomized study of negative and cognitive symptoms in early-phase schizophrenia. J. Clin. Psychiatry 71, 138-149. doi: 10.4088/JCP.08m04666yel
    • (2010) J. Clin. Psychiatry , vol.71 , pp. 138-149
    • Levkovitz, Y.1    Mendlovich, S.2    Riwkes, S.3    Braw, Y.4    Levkovitch-Verbin, H.5    Gal, G.6
  • 100
    • 70349314704 scopus 로고    scopus 로고
    • Induction of Nrf2 and xCT are neuroprotective antibiotic ceftriaxone in vitro
    • doi: 10.1111/j.1471-4159.2009.06347.x
    • Lewerenz, J., Albrecht, P., Tien, M. L., Henke, N., Karumbayaram, S., Kornblum, H. I., et al. (2009). Induction of Nrf2 and xCT are neuroprotective antibiotic ceftriaxone in vitro. J. Neurochem. 111, 332-343. doi: 10.1111/j.1471-4159.2009.06347.x
    • (2009) J. Neurochem. , vol.111 , pp. 332-343
    • Lewerenz, J.1    Albrecht, P.2    Tien, M.L.3    Henke, N.4    Karumbayaram, S.5    Kornblum, H.I.6
  • 103
    • 0032864675 scopus 로고    scopus 로고
    • MMP inhibition in prostate cancer
    • doi: 10.1111/j.1749-6632.1999.tb07690.
    • Lokeshwar, B. L. (1999). MMP inhibition in prostate cancer. Ann. N. Y. Acad Sci. 878, 271-289. doi: 10.1111/j.1749-6632.1999.tb07690.
    • (1999) Ann. N. Y. Acad Sci. , vol.878 , pp. 271-289
    • Lokeshwar, B.L.1
  • 105
    • 84865832247 scopus 로고    scopus 로고
    • Macrolides decrease the minimal inhibitory concentration against Pseudomonas aeruginosa from cystic fibrosis patients in biofilm
    • doi: 10.1186/1471-2180
    • Lutz, L., Pereira, D. C., Paiva, R. M., Zavascki, A. P., and Barth, A. L. (2012). Macrolides decrease the minimal inhibitory concentration against Pseudomonas aeruginosa from cystic fibrosis patients in biofilm. BMC Microbiol. 12:196. doi: 10.1186/1471-2180
    • (2012) BMC Microbiol. , vol.12 , pp. 196
    • Lutz, L.1    Pereira, D.C.2    Paiva, R.M.3    Zavascki, A.P.4    Barth, A.L.5
  • 107
    • 33644893050 scopus 로고    scopus 로고
    • Tetracycline inhibitsW7FW14F apomyoglobin fibril amyloid protein in a pre-fibrillar, highly cytotoxic state
    • Malmo, C., Vilasi, S., Iannuzzi, C., Tacchi, S., Cametti, C., Irace, G., et al. (2006). Tetracycline inhibitsW7FW14F apomyoglobin fibril amyloid protein in a pre-fibrillar, highly cytotoxic state. FASEB J. 20, 346-347.
    • (2006) FASEB J. , vol.20 , pp. 346-347
    • Malmo, C.1    Vilasi, S.2    Iannuzzi, C.3    Tacchi, S.4    Cametti, C.5    Irace, G.6
  • 108
    • 34548222188 scopus 로고    scopus 로고
    • Global burden of COPD: risk factors, prevalence, and future trends
    • Mannino, D. M., and Buist, A. S. (2007). Global burden of COPD: risk factors, prevalence, and future trends. Lancet 370, 765 61380-4
    • (2007) Lancet , vol.370
    • Mannino, D.M.1    Buist, A.S.2
  • 109
    • 0035105962 scopus 로고    scopus 로고
    • Glutamate transporters in neurologic disease
    • doi: 10.1001/
    • Maragakis, N. J., and Rothstein, J. D. (2001). Glutamate transporters in neurologic disease. Arch. Neurol. 58, 365-370. doi: 10.1001/
    • (2001) Arch. Neurol. , vol.58 , pp. 365-370
    • Maragakis, N.J.1    Rothstein, J.D.2
  • 110
    • 67649159074 scopus 로고    scopus 로고
    • Effects of Etanercept and Minocycline injury
    • doi: 10.1016/j.ejpain.2008.08.001
    • Marchand, F., Tsantoulas, C., Singh, D., Grist, J., Clark, A. K., Bradbury, E. J., et al. (2009). Effects of Etanercept and Minocycline injury. Eur. J. Pain 13, 673-681. doi: 10.1016/j.ejpain.2008.08.001
    • (2009) Eur. J. Pain , vol.13 , pp. 673-681
    • Marchand, F.1    Tsantoulas, C.2    Singh, D.3    Grist, J.4    Clark, A.K.5    Bradbury, E.J.6
  • 111
    • 47749155981 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance genes in natural environments
    • doi: 10.1126/science.
    • Martïnez, J. L. (2008). Antibiotics and antibiotic resistance genes in natural environments. Science 321, 365-367. doi: 10.1126/science.
    • (2008) Science , vol.321 , pp. 365-367
    • Martïnez, J.L.1
  • 112
    • 52149087280 scopus 로고    scopus 로고
    • A beta-lactam antibiotic dampens CNS damage in a mouse model of multiple sclerosis
    • doi: 10.1371/journal.pone.0003149
    • Melzer, N., Meuth, S. G., Torres-Salazar, D., Bittner, S., Zozulya, A. L., Weidenfeller, C., et al. (2008). A beta-lactam antibiotic dampens CNS damage in a mouse model of multiple sclerosis. PLoS ONE 3:e3149. doi: 10.1371/journal.pone.0003149
    • (2008) PLoS ONE , vol.3
    • Melzer, N.1    Meuth, S.G.2    Torres-Salazar, D.3    Bittner, S.4    Zozulya, A.L.5    Weidenfeller, C.6
  • 113
    • 11144354138 scopus 로고    scopus 로고
    • Minocycline reduces gadolinium lesions in multiple sclerosis
    • doi: 10.1002/ana.20111
    • Metz, L. M., Zhang, Y., Yeung, M., Patry, D. G., Bell, R. B., Stoian, C. A., et al. (2004). Minocycline reduces gadolinium lesions in multiple sclerosis. Ann. Neurol. 55, 756. doi: 10.1002/ana.20111
    • (2004) Ann. Neurol. , vol.55 , pp. 756
    • Metz, L.M.1    Zhang, Y.2    Yeung, M.3    Patry, D.G.4    Bell, R.B.5    Stoian, C.A.6
  • 114
    • 53349171466 scopus 로고    scopus 로고
    • Loss of the protein NUPR1 (p8) delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice
    • 10.1095/biolreprod.108.068304
    • Million Passe, C. M., White, C. R., King, M. W., Quirk, P. L., Iovanna, J. L., and Quirk, C. C. (2008). Loss of the protein NUPR1 (p8) delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol. Reprod. 10.1095/biolreprod.108.068304
    • (2008) Biol. Reprod.
    • Million Passe, C.M.1    White, C.R.2    King, M.W.3    Quirk, P.L.4    Iovanna, J.L.5    Quirk, C.C.6
  • 115
    • 84884254622 scopus 로고    scopus 로고
    • Microglia and synapse interactions: fine tuning neural circuits Cell
    • doi: 10.3389/fncel.2013.00070
    • Miyamoto, A., Wake, H., Moorhouse, A. J., and Nabekura, J. (2013). Microglia and synapse interactions: fine tuning neural circuits Cell. Neurosci. 7:70. doi: 10.3389/fncel.2013.00070
    • (2013) Neurosci. , vol.7 , pp. 70
    • Miyamoto, A.1    Wake, H.2    Moorhouse, A.J.3    Nabekura, J.4
  • 116
    • 60549086674 scopus 로고    scopus 로고
    • Clinical potential of minocycline for schizophrenia
    • doi: 10.2174/
    • Miyaoka, T. (2008). Clinical potential of minocycline for schizophrenia. CNS Neurol. Disord. Drug Targets 7, 376-381. doi: 10.2174/
    • (2008) CNS Neurol. Disord. Drug Targets , vol.7 , pp. 376-381
    • Miyaoka, T.1
  • 117
    • 84859571611 scopus 로고    scopus 로고
    • Minocycline as adjunctive therapy for patients depression: an open-label study
    • doi: 10.1016/j.pnpbp.2012. 02.002
    • Miyaoka, T., Wake, R., Furuya, M., Liaury, K., Ieda, M., Kawakami, K., et al. (2012). Minocycline as adjunctive therapy for patients depression: an open-label study. Prog. Neuropsychopharmacol. Biol. Psychiatry 37, 222-226. doi: 10.1016/j.pnpbp.2012. 02.002
    • (2012) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.37 , pp. 222-226
    • Miyaoka, T.1    Wake, R.2    Furuya, M.3    Liaury, K.4    Ieda, M.5    Kawakami, K.6
  • 119
    • 84874262774 scopus 로고    scopus 로고
    • Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular Sci
    • doi: 10.1073/pnas.1215722110
    • Mor, F., and Cohen, I. R. (2013). Beta-lactam antibiotics modulate T-cell functions and gene expression via covalent binding to cellular Sci. U.S.A. 110, 2981-2986. doi: 10.1073/pnas.1215722110
    • (2013) U.S.A. , vol.110 , pp. 2981-2986
    • Mor, F.1    Cohen, I.R.2
  • 121
    • 84884271300 scopus 로고
    • The enigma of cyclosporin A treatment in psoriasis: systemic efficacy versus topical non-responsiveness
    • Mrowietz, U. (1992). The enigma of cyclosporin A treatment in psoriasis: systemic efficacy versus topical non-responsiveness.
    • (1992)
    • Mrowietz, U.1
  • 122
    • 0032769834 scopus 로고    scopus 로고
    • Macrolide immunosuppressants
    • Mrowietz, U. (1999). Macrolide immunosuppressants. Eur. J. Dermatol. 9, 346-351.
    • (1999) Eur. J. Dermatol. , vol.9 , pp. 346-351
    • Mrowietz, U.1
  • 123
    • 34249661567 scopus 로고    scopus 로고
    • Azalides from azithromycin to new azalide derivatives
    • doi: 10.1038/ja.2007.10
    • Mutak, S. (2007). Azalides from azithromycin to new azalide derivatives. J. Antibiot. (Tokyo) 60, 85-122. doi: 10.1038/ja.2007.10
    • (2007) J. Antibiot. (Tokyo) , vol.60 , pp. 85-122
    • Mutak, S.1
  • 124
    • 0025896244 scopus 로고
    • Long-term low-dose administration of erythromycin diffuse panbronchiolitis
    • doi: 10.1159/000195915
    • Nagai, H., Shishido, H., Yoneda, R., Yamaguchi, E., Tamura, A., and Kurashima, A. (1991). Long-term low-dose administration of erythromycin diffuse panbronchiolitis. Respiration 58, 145-149. doi: 10.1159/000195915
    • (1991) Respiration , vol.58 , pp. 145-149
    • Nagai, H.1    Shishido, H.2    Yoneda, R.3    Yamaguchi, E.4    Tamura, A.5    Kurashima, A.6
  • 125
    • 77955438467 scopus 로고    scopus 로고
    • Clarithromycin attenuates myocardial Expert Opin
    • doi: 10.1517/14728222.2010.502890
    • Nakajima, T., Hishikari, K., Ogawa, M., Watanabe, R., Suzuki, J., Nagashima, A., et al. (2010). Clarithromycin attenuates myocardial Expert Opin. Ther. Targets 14, 881-893. doi: 10.1517/14728222.2010.502890
    • (2010) Ther. Targets , vol.14 , pp. 881-893
    • Nakajima, T.1    Hishikari, K.2    Ogawa, M.3    Watanabe, R.4    Suzuki, J.5    Nagashima, A.6
  • 126
    • 84873641892 scopus 로고    scopus 로고
    • Randomized trial ofminocycline in the treatment impairment
    • doi: 10.1212/WNL.0b013e31827b9121
    • Nakasujja, N., Miyahara, S., Evans, S., Lee, A., Musisi, S., Katabira, E., et al. (2013). Randomized trial ofminocycline in the treatment impairment. Neurology 80, 196-202. doi: 10.1212/WNL.0b013e31827b9121
    • (2013) Neurology , vol.80 , pp. 196-202
    • Nakasujja, N.1    Miyahara, S.2    Evans, S.3    Lee, A.4    Musisi, S.5    Katabira, E.6
  • 127
    • 79956158030 scopus 로고    scopus 로고
    • Beta-lactam antibiotic offers neuroprotection model by multiple mechanisms
    • doi: 10.1016/j.expneurol.2011.01.017
    • Nizzardo, M., Nardini, M., Ronchi, D., Salani, S., Donadoni, C., Fortunato, F., et al. (2011). Beta-lactam antibiotic offers neuroprotection model by multiple mechanisms. Exp. Neurol. 229, 214-225. doi: 10.1016/j.expneurol.2011.01.017
    • (2011) Exp. Neurol. , vol.229 , pp. 214-225
    • Nizzardo, M.1    Nardini, M.2    Ronchi, D.3    Salani, S.4    Donadoni, C.5    Fortunato, F.6
  • 128
    • 70349487545 scopus 로고    scopus 로고
    • Neuroprotective effects of tetracyclines: molecular targets, animal Neurol
    • doi: 10.2174/187152709788680689
    • Orsucci, D., Calsolaro, V., Mancuso, M., and Siciliano, G. (2009). Neuroprotective effects of tetracyclines: molecular targets, animal Neurol. Disord. Drug Targets. 8, 222-231. doi: 10.2174/187152709788680689
    • (2009) Disord. Drug Targets. , vol.8 , pp. 222-231
    • Orsucci, D.1    Calsolaro, V.2    Mancuso, M.3    Siciliano, G.4
  • 130
    • 79953861737 scopus 로고    scopus 로고
    • The effect of subantimicrobial serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial
    • Payne, J. B., Golub, L. M., Stoner, J. A., Lee, H. M., Reinhardt, R. A., Sorsa, T., et al. (2011). The effect of subantimicrobial serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. J. Am. Dent. Assoc.
    • (2011) J. Am. Dent. Assoc.
    • Payne, J.B.1    Golub, L.M.2    Stoner, J.A.3    Lee, H.M.4    Reinhardt, R.A.5    Sorsa, T.6
  • 131
    • 0027436439 scopus 로고
    • Adverse effects of macrolide antibacterials
    • Periti, P., Mazzei, T., Mini, E., and Novelli, A. (1993). Adverse effects of macrolide antibacterials. Drug Saf. 9, 346-364.
    • (1993) Drug Saf. , vol.9 , pp. 346-364
    • Periti, P.1    Mazzei, T.2    Mini, E.3    Novelli, A.4
  • 134
    • 30944458446 scopus 로고    scopus 로고
    • Extension of chronological life span in yeast signalling
    • doi: 10.1101/gad.1381406
    • Powers, R. W. III, Kaeberlein, M., Caldwell, S. D., Kennedy, B. K., and Fields, S. (2006). Extension of chronological life span in yeast signalling. Genes Dev. 20, 174-184. doi: 10.1101/gad.1381406
    • (2006) Genes Dev. , vol.20 , pp. 174-184
    • Powers, R.W.1    Kaeberlein, M.2    Caldwell, S.D.3    Kennedy, B.K.4    Fields, S.5
  • 135
    • 35348912506 scopus 로고    scopus 로고
    • Developmentally regulated synthesis of p8, a stress-associated transcription cofactor, in diapause franciscana
    • doi: 10.1379/CSC-275.1
    • Qiu, Z., and MacRae, T. H. (2007). Developmentally regulated synthesis of p8, a stress-associated transcription cofactor, in diapause franciscana. Cell Stress Chaperones 12, 255-264. doi: 10.1379/CSC-275.1
    • (2007) Cell Stress Chaperones , vol.12 , pp. 255-264
    • Qiu, Z.1    MacRae, T.H.2
  • 137
    • 84870422766 scopus 로고    scopus 로고
    • Glutamate transporter 1: target for the treatment of alcohol dependence
    • 10.2174/092986712803530511
    • Rao, P. S., and Sari, Y. (2012). Glutamate transporter 1: target for the treatment of alcohol dependence. Curr. Med. Chem. 10.2174/092986712803530511
    • (2012) Curr. Med. Chem.
    • Rao, P.S.1    Sari, Y.2
  • 138
    • 80053572219 scopus 로고    scopus 로고
    • Glutamate transporter subtype 1 (GLT-1) activator ceftriaxone attenuates hyperactivity and behavioral sensitization in rats
    • doi: 10.1016/j.drugalcdep.2011.03.022
    • Rasmussen, B., Unterwald, E. M., and Rawls, S. M. (2011). Glutamate transporter subtype 1 (GLT-1) activator ceftriaxone attenuates hyperactivity and behavioral sensitization in rats. Drug Alcohol Depend. 118, 484-488. doi: 10.1016/j.drugalcdep.2011.03.022
    • (2011) Drug Alcohol Depend. , vol.118 , pp. 484-488
    • Rasmussen, B.1    Unterwald, E.M.2    Rawls, S.M.3
  • 139
    • 84871558375 scopus 로고    scopus 로고
    • Tacrolimus in transplant rejection
    • doi: 10.1517/14656566.2013.751374
    • Rath, T. (2013). Tacrolimus in transplant rejection. Expert Opin. Pharmacother. 14, 115-122. doi: 10.1517/14656566.2013.751374
    • (2013) Expert Opin. Pharmacother. , vol.14 , pp. 115-122
    • Rath, T.1
  • 141
    • 77649191179 scopus 로고    scopus 로고
    • Beta-lactam antibiotic reduces morphine analgesic GLT-1 transporter activation
    • doi: 10.1016/j.drugalcdep.2009.10.010
    • Rawls, S. M., Zielinski, M., Patel, H., Sacavage, S., Baron, D. A., and Patel, D. (2010b). Beta-lactam antibiotic reduces morphine analgesic GLT-1 transporter activation. Drug Alcohol Depend. 107, 261-263. doi: 10.1016/j.drugalcdep.2009.10.010
    • (2010) Drug Alcohol Depend. , vol.107 , pp. 261-263
    • Rawls, S.M.1    Zielinski, M.2    Patel, H.3    Sacavage, S.4    Baron, D.A.5    Patel, D.6
  • 142
    • 41249083786 scopus 로고    scopus 로고
    • The beta-lactam antibiotic ceftriaxone inhibits physical dependence withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians
    • Rawls, S. M., Cavallo, F., Capasso, A., Ding, Z., and Raffa, R. B. (2008). The beta-lactam antibiotic ceftriaxone inhibits physical dependence withdrawal from cocaine, amphetamine, methamphetamine, and clorazepate in planarians. Eur. J. Pharmacol. 584, 278
    • (2008) Eur. J. Pharmacol. , vol.584 , pp. 278
    • Rawls, S.M.1    Cavallo, F.2    Capasso, A.3    Ding, Z.4    Raffa, R.B.5
  • 144
    • 80052792018 scopus 로고    scopus 로고
    • Antibiotics as signal molecules
    • doi: 10.1021/
    • Romero, D., Traxler, M. F., López, D., and Kolter, R. (2011). Antibiotics as signal molecules.Chem Rev. 111, 5492-5505. doi: 10.1021/
    • (2011) Chem Rev. , vol.111 , pp. 5492-5505
    • Romero, D.1    Traxler, M.F.2    López, D.3    Kolter, R.4
  • 145
    • 19944428649 scopus 로고    scopus 로고
    • Beta-lactam antibiotics offer neuroprotection glutamate transporter expression
    • doi: 10.1038/nature03180
    • Rothstein, J. D., Patel, S., Regan, M. R., Haenggeli, C., Huang, Y. H., Bergles, D. E., et al. (2005). Beta-lactam antibiotics offer neuroprotection glutamate transporter expression. Nature 433, 73-77. doi: 10.1038/nature03180
    • (2005) Nature , vol.433 , pp. 73-77
    • Rothstein, J.D.1    Patel, S.2    Regan, M.R.3    Haenggeli, C.4    Huang, Y.H.5    Bergles, D.E.6
  • 146
    • 84856596122 scopus 로고    scopus 로고
    • Minocycline treatment reverses ultrasonic vocalization mouse model of Fragile X Syndrome
    • doi: 10.1016/j.brainres.2011.12.041
    • Rotschafer, S. E., Trujillo, M. S., Dansie, L. E., Ethell, I. M., and Razak, K. A. (2012). Minocycline treatment reverses ultrasonic vocalization mouse model of Fragile X Syndrome. Brain Res. 1439, 7-14. doi: 10.1016/j.brainres.2011.12.041
    • (2012) Brain Res. , vol.1439 , pp. 7-14
    • Rotschafer, S.E.1    Trujillo, M.S.2    Dansie, L.E.3    Ethell, I.M.4    Razak, K.A.5
  • 147
    • 80054114442 scopus 로고    scopus 로고
    • Jack of all trades: pleiotropy and the application of chemically modified acute respiratory distress syndrome
    • doi: 10.1016/j.phrs.2011.06.012
    • Roy, S. K., Kendrick, D., Sadowitz, B. D., and Gatto, L. (2011). Jack of all trades: pleiotropy and the application of chemically modified acute respiratory distress syndrome. Pharmacol. Res. 64, 580-589. doi: 10.1016/j.phrs.2011.06.012
    • (2011) Pharmacol. Res. , vol.64 , pp. 580-589
    • Roy, S.K.1    Kendrick, D.2    Sadowitz, B.D.3    Gatto, L.4
  • 149
    • 33646548754 scopus 로고    scopus 로고
    • Chemically modified tetracyclines (CMT pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition
    • doi: 10.1016/
    • Salo, T., Soini, Y., Oiva, J., Kariylitalo, Nissinen, A., Biancari, F., et al. (2006). Chemically modified tetracyclines (CMT pathologic remodellation of human aortic valve stenosis via MMP-9 and VEGF inhibition. Int. J. Cardiol. 111, 358-364. doi: 10.1016/
    • (2006) Int. J. Cardiol. , vol.111 , pp. 358-364
    • Salo, T.1    Soini, Y.2    Oiva, J.3    Kariylitalo, N.A.4    Biancari, F.5
  • 151
    • 84876727807 scopus 로고    scopus 로고
    • Effects of ceftriaxone on the acquisition and maintenance of ethanol and adult female alcohol-preferring (P) rats
    • doi: 10.1016/j.neuroscience.2013.03.016
    • Sari, Y., Franklin, K. M., Alazizi, A., Rao, P. S., and Bell, R. L. (2013). Effects of ceftriaxone on the acquisition and maintenance of ethanol and adult female alcohol-preferring (P) rats. Neuroscience 241, 229-238. doi: 10.1016/j.neuroscience.2013.03.016
    • (2013) Neuroscience , vol.241 , pp. 229-238
    • Sari, Y.1    Franklin, K.M.2    Alazizi, A.3    Rao, P.S.4    Bell, R.L.5
  • 152
    • 79955405349 scopus 로고    scopus 로고
    • Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption rats
    • doi: 10.1093/alcalc/agr023
    • Sari, Y., Sakai, M., Weedman, J. M., Rebec, G. V., and Bell, R. L. (2011). Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption rats. Alcohol Alcohol. 46, 239-234. doi: 10.1093/alcalc/agr023
    • (2011) Alcohol Alcohol. , vol.46 , pp. 239-234
    • Sari, Y.1    Sakai, M.2    Weedman, J.M.3    Rebec, G.V.4    Bell, R.L.5
  • 154
    • 84856532498 scopus 로고    scopus 로고
    • Human matrix metalloproteinases: an involved in several pathological processes
    • doi: 10.1016/j.mam.2011.10.015
    • Sbardella, D., Fasciglione, G. F., Gioia, M., Ciaccio, C., Tundo, G. R., Marini, S., et al. (2012). Human matrix metalloproteinases: an involved in several pathological processes. Mol. Aspects Med. 33, 119-208. doi: 10.1016/j.mam.2011.10.015
    • (2012) Mol. Aspects Med. , vol.33 , pp. 119-208
    • Sbardella, D.1    Fasciglione, G.F.2    Gioia, M.3    Ciaccio, C.4    Tundo, G.R.5    Marini, S.6
  • 158
    • 84875543900 scopus 로고    scopus 로고
    • Effect of long-term, low exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial
    • Serisier, D. J., Martin, M. L., McGuckin, M. A., Lourie, R., Chen, A. C., Brain, B., et al. (2013). Effect of long-term, low exacerbations among patients with non-cystic fibrosis bronchiectasis: the BLESS randomized controlled trial. JAMA 309, 1260
    • (2013) JAMA , vol.309 , pp. 1260
    • Serisier, D.J.1    Martin, M.L.2    McGuckin, M.A.3    Lourie, R.4    Chen, A.C.5    Brain, B.6
  • 159
    • 0030027692 scopus 로고    scopus 로고
    • The effect of minocycline arthritis: correlation of arthritis suppression with enhanced T cell calcium flux
    • doi: 10.1006/cimm.1996.0027
    • Sewell, K. L., Breedveld, F., Furrie, E., O'Brien, J., Brinckerhoff, C., Dynesius-Trentham, R., et al. (1996). The effect of minocycline arthritis: correlation of arthritis suppression with enhanced T cell calcium flux. Cell. Immunol. 167, 195-204. doi: 10.1006/cimm.1996.0027
    • (1996) Cell. Immunol. , vol.167 , pp. 195-204
    • Sewell, K.L.1    Breedveld, F.2    Furrie, E.3    O'Brien, J.4    Brinckerhoff, C.5    Dynesius-Trentham, R.6
  • 160
    • 84863466498 scopus 로고    scopus 로고
    • Adverse events induced by ceftriaxone: a 10-year review of reported cases to Iranian Clin
    • doi: 10.1111/j.1365-2710.2011.01321.x
    • Shalviri, G., Yousefian, S., and Gholami, K. (2012). Adverse events induced by ceftriaxone: a 10-year review of reported cases to Iranian Clin. Pharm. Ther. 37, 448-451. doi: 10.1111/j.1365-2710.2011.01321.x
    • (2012) Pharm. Ther. , vol.37 , pp. 448-451
    • Shalviri, G.1    Yousefian, S.2    Gholami, K.3
  • 164
    • 0034641962 scopus 로고    scopus 로고
    • Quorum-sensing signals indicate infected with bacterial biofilms
    • doi: 10.1038/35037627
    • Singh, P. K., Schaefer, A. L., Parsek, M. R., Moninger, T. O., Welsh, M. J., and Greenberg, E. P. (2000). Quorum-sensing signals indicate infected with bacterial biofilms. Nature 407, 762-764. doi: 10.1038/35037627
    • (2000) Nature , vol.407 , pp. 762-764
    • Singh, P.K.1    Schaefer, A.L.2    Parsek, M.R.3    Moninger, T.O.4    Welsh, M.J.5    Greenberg, E.P.6
  • 165
    • 78249258414 scopus 로고    scopus 로고
    • Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline Opin
    • doi: 10.1517/14728222.2010.531012
    • Sirangelo, I., and Irace, G. (2010). Inhibition of aggregate formation as therapeutic target in protein misfolding diseases: effect of tetracycline Opin. Ther. Targets. 14, 1311-1321. doi: 10.1517/14728222.2010.531012
    • (2010) Ther. Targets. , vol.14 , pp. 1311-1321
    • Sirangelo, I.1    Irace, G.2
  • 166
    • 0344483895 scopus 로고    scopus 로고
    • Specificity of inhibition of matrix metalloproteinase activity structure of the enzyme
    • doi: 10.1002/1529-0131(199906)42:6<1140::AID-ANR10>3.0.CO;2
    • Smith, G. N. Jr., Mickler, E. A., Hasty, K. A., and Brandt, K. D. (1999). Specificity of inhibition of matrix metalloproteinase activity structure of the enzyme. Arthritis Rheum. 42, 1140-1146. doi: 10.1002/1529-0131(199906)42:6<1140::AID-ANR10>3.0.CO;2
    • (1999) Arthritis Rheum. , vol.42 , pp. 1140-1146
    • Smith Jr., G.N.1    Mickler, E.A.2    Hasty, K.A.3    Brandt, K.D.4
  • 168
    • 80051650467 scopus 로고    scopus 로고
    • Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation primed reinstatement of cocaine-seeking
    • doi: 10.1016/j.bbr.2011.07.041
    • Sondheimer, I., and Knackstedt, L. A. (2011). Ceftriaxone prevents the induction of cocaine sensitization and produces enduring attenuation primed reinstatement of cocaine-seeking. Behav. Brain Res. 225, 252-258. doi: 10.1016/j.bbr.2011.07.041
    • (2011) Behav. Brain Res. , vol.225 , pp. 252-258
    • Sondheimer, I.1    Knackstedt, L.A.2
  • 170
    • 84874404425 scopus 로고    scopus 로고
    • Membrane-associated matrix proteolysis and heart failure
    • 10.1161/CIRCRESAHA.112.266882
    • Spinale, F. G., Janicki, J. S., and Zile, M. R. (2013). Membrane-associated matrix proteolysis and heart failure. Circ. Res. 10.1161/CIRCRESAHA.112.266882
    • (2013) Circ. Res.
    • Spinale, F.G.1    Janicki, J.S.2    Zile, M.R.3
  • 172
    • 84964119227 scopus 로고
    • Further observations of the "animal protein factor"
    • Stokstad, E. L. R., and Jukes, T. H. (1950). Further observations of the "animal protein factor". Exp. Biol. Med. 72, 523
    • (1950) Exp. Biol. Med. , vol.72 , pp. 523
    • Stokstad, E.L.R.1    Jukes, T.H.2
  • 173
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and household size
    • doi: 10.1136/bmj.299.6710.1259
    • Strachan, D. P. (1989). Hay fever, hygiene, and household size. BMJ 299, 1259-1260. doi: 10.1136/bmj.299.6710.1259
    • (1989) BMJ , vol.299 , pp. 1259-1260
    • Strachan, D.P.1
  • 174
    • 84866434383 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship of a novel class of 15 known as '11a-azalides'
    • doi: 10.1016/j.bmc.2012.08.007
    • Sugimoto, T., Tanikawa, T., Suzuki, K., and Yamasaki, Y. (2012). Synthesis and structure-activity relationship of a novel class of 15 known as '11a-azalides'. Bioorg. Med. Chem. 20, 5787-5801. doi: 10.1016/j.bmc.2012.08.007
    • (2012) Bioorg. Med. Chem. , vol.20 , pp. 5787-5801
    • Sugimoto, T.1    Tanikawa, T.2    Suzuki, K.3    Yamasaki, Y.4
  • 176
    • 84869084761 scopus 로고    scopus 로고
    • Novel effects of macrolide antibiotics on Cardiovasc
    • doi: 10.1111/j.1755-5922.2011.00303.x
    • Suzuki, J., Ogawa, M., Hishikari, K., Watanabe, R., Takayama, K., Hirata, Y., et al. (2012). Novel effects of macrolide antibiotics on Cardiovasc. Ther. 30, 301-307. doi: 10.1111/j.1755-5922.2011.00303.x
    • (2012) Ther. , vol.30 , pp. 301-307
    • Suzuki, J.1    Ogawa, M.2    Hishikari, K.3    Watanabe, R.4    Takayama, K.5    Hirata, Y.6
  • 177
    • 78649877212 scopus 로고    scopus 로고
    • Minocycline prevents osmotic demyelination activation of microglia
    • doi: 10.1681/ASN.2010040438
    • Suzuki, H., Sugimura, Y., Iwama, S., Suzuki, H., Nobuaki, O., Nagasaki, H., et al. (2010). Minocycline prevents osmotic demyelination activation of microglia. J. Am. Soc. Nephrol. 21, 2090-2098. doi: 10.1681/ASN.2010040438
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 2090-2098
    • Suzuki, H.1    Sugimura, Y.2    Iwama, S.3    Suzuki, H.4    Nobuaki, O.5    Nagasaki, H.6
  • 178
    • 5444229881 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of Col tetracycline derivative with potent matrix metalloproteinase and antitumor properties
    • doi: 10.1158/
    • Syed, S., Takimoto, C., Hidalgo, M., Rizzo, J., Kuhn, J. G., Hammond, L. A., et al. (2004). A phase I and pharmacokinetic study of Col tetracycline derivative with potent matrix metalloproteinase and antitumor properties. Clin. Cancer Res. 10, 6512-6521. doi: 10.1158/
    • (2004) Clin. Cancer Res. , vol.10 , pp. 6512-6521
    • Syed, S.1    Takimoto, C.2    Hidalgo, M.3    Rizzo, J.4    Kuhn, J.G.5    Hammond, L.A.6
  • 180
    • 0029154442 scopus 로고
    • Effect of clarithromycin on sputum production and its rheological properties tract infections
    • doi: 10.1128/AAC.39.8.1688
    • Tamaoki, J., Takeyama, K., Tagaya, E., and Konno, K. (1995). Effect of clarithromycin on sputum production and its rheological properties tract infections. Antimicrob. Agents Chemother. 39, 1688-1690. doi: 10.1128/AAC.39.8.1688
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1688-1690
    • Tamaoki, J.1    Takeyama, K.2    Tagaya, E.3    Konno, K.4
  • 181
    • 84878665825 scopus 로고    scopus 로고
    • Nonantibiotic macrolides prevent human neutrophil stasis and airway surface liquid volume depletion
    • doi: 10.1152/ajplung.
    • Tarran, R., Sabater, J. R., Clarke, T. C., Tan, C. D., Davies, C. M., Liu, J., et al. (2013). Nonantibiotic macrolides prevent human neutrophil stasis and airway surface liquid volume depletion. Am. J. Physiol. Lung. Cell. Mol. Physiol. 304, L746-L756. doi: 10.1152/ajplung.
    • (2013) Am. J. Physiol. Lung. Cell. Mol. Physiol. , vol.304
    • Tarran, R.1    Sabater, J.R.2    Clarke, T.C.3    Tan, C.D.4    Davies, C.M.5    Liu, J.6
  • 182
    • 37349067977 scopus 로고    scopus 로고
    • Suppression of Pseudomonas aeruginosa macrolides: a promising strategy or an oriental mystery? J
    • doi: 10.1007/s10156-007-
    • Tateda, K., Ishii, Y., Kimura, S., Horikawa, M., Miyairi, S., and Yamaguchi, K. (2007). Suppression of Pseudomonas aeruginosa macrolides: a promising strategy or an oriental mystery? J. Infect. Chemother. 13, 357-367. doi: 10.1007/s10156-007-
    • (2007) Infect. Chemother. , vol.13 , pp. 357-367
    • Tateda, K.1    Ishii, Y.2    Kimura, S.3    Horikawa, M.4    Miyairi, S.5    Yamaguchi, K.6
  • 183
    • 0028856292 scopus 로고
    • Defective protein folding as a basis of human disease
    • 0004(00)89100-8
    • Thomas, P. J., Qu, B. H., and Pedersen, P. L. (1995). Defective protein folding as a basis of human disease. Trends Biochem. Sci. 0004(00)89100-8
    • (1995) Trends Biochem. Sci.
    • Thomas, P.J.1    Qu, B.H.2    Pedersen, P.L.3
  • 184
    • 59849095508 scopus 로고    scopus 로고
    • The beta-lactam antibiotic, improves survival, increases glutamate uptake and induces neurotrophins in stroke
    • doi: 10.1097/HJH.
    • Thöne-Reineke, C., Neumann, C., Namsolleck, P., Schmerbach, K., Krikov, M., Schefe, J. H., et al. (2008). The beta-lactam antibiotic, improves survival, increases glutamate uptake and induces neurotrophins in stroke. J. Hypertens. 26, 2426-2435. doi: 10.1097/HJH.
    • (2008) J. Hypertens. , vol.26 , pp. 2426-2435
    • Thöne-Reineke, C.1    Neumann, C.2    Namsolleck, P.3    Schmerbach, K.4    Krikov, M.5    Schefe, J.H.6
  • 185
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective inhibiting activation and proliferation of microglia
    • Tikka, T. M., Fiebich, B. L., Goldsteins, G., Keinanen, R., and Koistinaho, J. (2001). Minocycline, a tetracycline derivative, is neuroprotective inhibiting activation and proliferation of microglia. J. Neurosci. 21, 2580-2588.
    • (2001) J. Neurosci. , vol.21 , pp. 2580-2588
    • Tikka, T.M.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 186
    • 0036209082 scopus 로고    scopus 로고
    • Minocycline prevents neurotoxicity fluid from patients with motor neurone disease
    • doi: 10.1093/brain/awf068
    • Tikka, T. M., Vartiainen, N. E., Goldsteins, G., Oja, S. S., Andersen, P. M., Marklund, S. L., et al. (2002). Minocycline prevents neurotoxicity fluid from patients with motor neurone disease. Brain 125, 722-731. doi: 10.1093/brain/awf068
    • (2002) Brain , vol.125 , pp. 722-731
    • Tikka, T.M.1    Vartiainen, N.E.2    Goldsteins, G.3    Oja, S.S.4    Andersen, P.M.5    Marklund, S.L.6
  • 187
    • 84865798081 scopus 로고    scopus 로고
    • Ceftriaxone normalizes nucleus transmission, glutamate transport, and export following cocaine self-administration and extinction training
    • 10.1523/JNEUROSCI.1976-12.2012
    • Trantham-Davidson, H., LaLumiere, R. T., Reissner, K. J., Kalivas, P. W., and Knackstedt, L. A. (2012). Ceftriaxone normalizes nucleus transmission, glutamate transport, and export following cocaine self-administration and extinction training. J. Neurosci. 10.1523/JNEUROSCI.1976-12.2012
    • (2012) J. Neurosci.
    • Trantham-Davidson, H.1    LaLumiere, R.T.2    Reissner, K.J.3    Kalivas, P.W.4    Knackstedt, L.A.5
  • 188
    • 84870891391 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhoea
    • doi: 10.2217/fmb.12.117
    • Unemo, M., and Nicholas, R. A. (2012). Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhoea. doi: 10.2217/fmb.12.117
    • (2012)
    • Unemo, M.1    Nicholas, R.A.2
  • 189
    • 0036195462 scopus 로고    scopus 로고
    • p8 is critical for tumour development induced and E1A oncogene
    • doi: 10.1093/embo-reports/kvf023
    • Vasseur, S., Hoffmeister, A., Garcia, S., Bagnis, C., Dagorn, J. C., and Iovanna, J. L. (2002). p8 is critical for tumour development induced and E1A oncogene. EMBO Rep. 3, 165-170. doi: 10.1093/embo-reports/kvf023
    • (2002) EMBO Rep. , vol.3 , pp. 165-170
    • Vasseur, S.1    Hoffmeister, A.2    Garcia, S.3    Bagnis, C.4    Dagorn, J.C.5    Iovanna, J.L.6
  • 190
    • 77953534964 scopus 로고    scopus 로고
    • Pharmacological evaluation of glutamate transporter 1 (GLT cerebral ischemia/reperfusion injury
    • doi: 10.1016/j.ejphar.2010.04.021
    • Verma, R., Mishra, V., Sasmal, D., and Raghubir, R. (2010). Pharmacological evaluation of glutamate transporter 1 (GLT cerebral ischemia/reperfusion injury. Eur. J. Pharmacol. 638, 65-71. doi: 10.1016/j.ejphar.2010.04.021
    • (2010) Eur. J. Pharmacol. , vol.638 , pp. 65-71
    • Verma, R.1    Mishra, V.2    Sasmal, D.3    Raghubir, R.4
  • 193
    • 0041335559 scopus 로고    scopus 로고
    • Minocycline inhibits caspase cell death pathways in models of Huntington's disease
    • doi: 10.1073/pnas.1832501100
    • Wang, X., Zhu, S., Drozda, M., Zhang, W., Stavrovskaya, I. G., Cattaneo, E., et al. (2003). Minocycline inhibits caspase cell death pathways in models of Huntington's disease. Proc. Natl. Acad. Sci. U.S.A. 100, 10483-10487. doi: 10.1073/pnas.1832501100
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 10483-10487
    • Wang, X.1    Zhu, S.2    Drozda, M.3    Zhang, W.4    Stavrovskaya, I.G.5    Cattaneo, E.6
  • 194
    • 84884246320 scopus 로고    scopus 로고
    • Minocycline, a microglial inhibitor, reduces economic exchange
    • doi: 10.1038/srep01685
    • Watabe, M., Kato, T. A., Tsuboi, S., Ishikawa, K., Hashiya, K., Monji, A., et al. (2013). Minocycline, a microglial inhibitor, reduces economic exchange. Sci. Rep. 3, 1685. doi: 10.1038/srep01685
    • (2013) Sci. Rep. , vol.3 , pp. 1685
    • Watabe, M.1    Kato, T.A.2    Tsuboi, S.3    Ishikawa, K.4    Hashiya, K.5    Monji, A.6
  • 195
    • 34147148650 scopus 로고    scopus 로고
    • Anti-inflammatory activity of tetracyclines
    • doi: 10.1016/j.det.
    • Webster, G., and Del Rosso, J. Q. (2007). Anti-inflammatory activity of tetracyclines. Dermatol. Clin. 25, 133-135. doi: 10.1016/j.det.
    • (2007) Dermatol. Clin. , vol.25 , pp. 133-135
    • Webster, G.1    Del Rosso, J.Q.2
  • 196
    • 84865955492 scopus 로고    scopus 로고
    • The beta-lactam antibiotic, ceftriaxone, provides neuroprotective and anti-inflammation response in a rat model of traumatic brain injury
    • doi: 10.1097/TA.
    • Wei, J., Pan, X., Pei, Z., Wang, W., Qiu, W., Shi, Z., et al. (2012). The beta-lactam antibiotic, ceftriaxone, provides neuroprotective and anti-inflammation response in a rat model of traumatic brain injury. J. Trauma Acute Care Surg. 73, 654-660. doi: 10.1097/TA.
    • (2012) J. Trauma Acute Care Surg. , vol.73 , pp. 654-660
    • Wei, J.1    Pan, X.2    Pei, Z.3    Wang, W.4    Qiu, W.5    Shi, Z.6
  • 197
    • 18244366080 scopus 로고    scopus 로고
    • The anti-inflammatory effects of tetracyclines
    • Weinberg, J. M. (2005). The anti-inflammatory effects of tetracyclines. Cutis 75, 6-11.
    • (2005) Cutis , vol.75 , pp. 6-11
    • Weinberg, J.M.1
  • 198
    • 0029418483 scopus 로고
    • Mechanism of action of rapamycin: regulation of G1-phase progression in eukaryotic cells
    • doi: 10.1007/978-1-4615-1809-9_5
    • Wiederrecht, G. J., Sabers, C. J., Brunn, G. J., Martin, M. M., Dumont, F. J., and Abraham, R. T. (1995). Mechanism of action of rapamycin: regulation of G1-phase progression in eukaryotic cells. Prog. Cell Cycle Res. 1, 53-71. doi: 10.1007/978-1-4615-1809-9_5
    • (1995) Prog. Cell Cycle Res. , vol.1 , pp. 53-71
    • Wiederrecht, G.J.1    Sabers, C.J.2    Brunn, G.J.3    Martin, M.M.4    Dumont, F.J.5    Abraham, R.T.6
  • 200
    • 0037669432 scopus 로고    scopus 로고
    • Tacrolimus-associated posterior reversible allogeneic haematopoietic stem cell transplantation
    • doi: 10.1046/j.1365-2141.2003.04447.x
    • Wong, R., Beguelin, G. Z., de Lima, M., Giralt, S. A., Hosing, C., Ippoliti, C., et al. (2003). Tacrolimus-associated posterior reversible allogeneic haematopoietic stem cell transplantation. Br. J. Haematol. 122, 128-134. doi: 10.1046/j.1365-2141.2003.04447.x
    • (2003) Br. J. Haematol. , vol.122 , pp. 128-134
    • Wong, R.1    Beguelin, G.Z.2    de Lima, M.3    Giralt, S.A.4    Hosing, C.5    Ippoliti, C.6
  • 201
    • 79951965682 scopus 로고    scopus 로고
    • The risk of hypotension following co calcium-channel blockers
    • doi: 10.1503/cmaj.100702
    • Wright, A. J., Gomes, T., Mamdani, M. M., Horn, J. R., and Juurlink, D. N. (2011). The risk of hypotension following co calcium-channel blockers. CMAJ 183, 303-307. doi: 10.1503/cmaj.100702
    • (2011) CMAJ , vol.183 , pp. 303-307
    • Wright, A.J.1    Gomes, T.2    Mamdani, M.M.3    Horn, J.R.4    Juurlink, D.N.5
  • 202
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu, D. C., Jackson-Lewis, V., Vila, M., Tieu, K., Teismann, P., Vadseth, C., et al. (2002). Blockade of microglial activation is neuroprotective phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 22, 1763-1771.
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6
  • 203
    • 77955301448 scopus 로고    scopus 로고
    • Tacrolimus-associated posterior reversible encephalopathy organ transplantation
    • doi: 10.1159/000319032
    • Wu, Q., Marescaux, C., Wolff, V., Jeung, M. Y., Kessler, R., Lauer, V., et al. (2010). Tacrolimus-associated posterior reversible encephalopathy organ transplantation. Eur. Neurol. 64, 169-177. doi: 10.1159/000319032
    • (2010) Eur. Neurol. , vol.64 , pp. 169-177
    • Wu, Q.1    Marescaux, C.2    Wolff, V.3    Jeung, M.Y.4    Kessler, R.5    Lauer, V.6
  • 204
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • doi: 10.1016/j.cell.
    • Wullschleger, S., Loewith, R., and Hall, M. N. (2006). TOR signaling in growth and metabolism. Cell 124, 471-484. doi: 10.1016/j.cell.
    • (2006) Cell , vol.124 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 205
    • 33644871218 scopus 로고    scopus 로고
    • The truth about antibiotics
    • doi: 10.1016/j.ijmm.
    • Yim, G., Wang, H. H., and Davies, J. (2006). The truth about antibiotics. Int. J. Med. Microbiol. 296, 163-170. doi: 10.1016/j.ijmm.
    • (2006) Int. J. Med. Microbiol. , vol.296 , pp. 163-170
    • Yim, G.1    Wang, H.H.2    Davies, J.3
  • 208
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, protects against focal cerebral ischemia with a wide therapeutic window
    • doi: 10.1073/
    • Yrjanheikki, J., Tikka, T., Keinanen, R., Goldsteins, G., Chan, P. H., and Koistinaho, J. (1999). A tetracycline derivative, minocycline, protects against focal cerebral ischemia with a wide therapeutic window. Proc. Natl. Acad. Sci. U.S.A. 96, 13496-13500. doi: 10.1073/
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 13496-13500
    • Yrjanheikki, J.1    Tikka, T.2    Keinanen, R.3    Goldsteins, G.4    Chan, P.H.5    Koistinaho, J.6
  • 209
    • 65649135141 scopus 로고    scopus 로고
    • Role of NF-kappaB activation and peroxisome proliferatoreffect of rifampin on inducible nitric oxide synthase transcription in human lung epithelial cells
    • 10.1128/AAC.00961-08
    • Yuhas, Y., Berent, E., Cohen, R., and Ashkenazi, S. (2009). Role of NF-kappaB activation and peroxisome proliferatoreffect of rifampin on inducible nitric oxide synthase transcription in human lung epithelial cells. Antimicrob. Agents Chemother. 10.1128/AAC.00961-08
    • (2009) Antimicrob. Agents Chemother.
    • Yuhas, Y.1    Berent, E.2    Cohen, R.3    Ashkenazi, S.4
  • 210
    • 34249039892 scopus 로고    scopus 로고
    • The clinical response to minocycline in accompanied by beneficial immune changes: a pilot study
    • Zabad, R. K., Metz, L. M., Todoruk, T. R., Zhang, Y., Mitchell, J. R., Yeung, M., et al. (2007). The clinical response to minocycline in accompanied by beneficial immune changes: a pilot study. Mult. Scler. 13, 517-526.
    • (2007) Mult. Scler. , vol.13 , pp. 517-526
    • Zabad, R.K.1    Metz, L.M.2    Todoruk, T.R.3    Zhang, Y.4    Mitchell, J.R.5    Yeung, M.6
  • 211
    • 84881060646 scopus 로고    scopus 로고
    • Inhibitory impacts of chemically modified tetracycline cervical cancer cells
    • doi: 10.1097/CAD.0b013e328362b1be
    • Zhao, L., Xu, J., Yang, Y., Chong, Y., Liu, C., Jiao, Y., et al. (2013a). Inhibitory impacts of chemically modified tetracycline cervical cancer cells. Anticancer Drugs 24, 799-809. doi: 10.1097/CAD.0b013e328362b1be
    • (2013) Anticancer Drugs , vol.24 , pp. 799-809
    • Zhao, L.1    Xu, J.2    Yang, Y.3    Chong, Y.4    Liu, C.5    Jiao, Y.6
  • 213
    • 0037007645 scopus 로고    scopus 로고
    • Minocycline inhibits cytochrome c release and delays lateral sclerosis in mice
    • doi: 10.1038/417074a
    • Zhu, S., Stavrovskaya, I. G., Drozda, M., Kim, B. Y., Ona, V., Li, M., et al. (2002). Minocycline inhibits cytochrome c release and delays lateral sclerosis in mice. Nature 417, 74-78. doi: 10.1038/417074a
    • (2002) Nature , vol.417 , pp. 74-78
    • Zhu, S.1    Stavrovskaya, I.G.2    Drozda, M.3    Kim, B.Y.4    Ona, V.5    Li, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.