-
1
-
-
34548660457
-
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
-
Rabe KF, Hurd S, Anzueto A et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2007; 176:532-55.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 532-555
-
-
Rabe, K.F.1
Hurd, S.2
Anzueto, A.3
-
3
-
-
0029978363
-
Risk factors for the development of chronic obstructive pulmonary disease
-
Silverman EK, Speizer FE. Risk factors for the development of chronic obstructive pulmonary disease. Med Clin North Am 1996; 80:501-22.
-
(1996)
Med Clin North Am
, vol.80
, pp. 501-522
-
-
Silverman, E.K.1
Speizer, F.E.2
-
4
-
-
65949097274
-
How will genetic approaches assist in the management of respiratory diseases?
-
Hall IP. How will genetic approaches assist in the management of respiratory diseases?. Curr Opin Pharmacol 2009; 9:256-61.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 256-261
-
-
Hall, I.P.1
-
5
-
-
64849094813
-
What can naturally occurring mutations tell us about the pathogenesis of COPD?
-
Marciniak SJ, Lomas DA. What can naturally occurring mutations tell us about the pathogenesis of COPD?. Thorax 2009; 64:359-64.
-
(2009)
Thorax
, vol.64
, pp. 359-364
-
-
Marciniak, S.J.1
Lomas, D.A.2
-
6
-
-
0013832667
-
The familial occurrence of chronic obstructive pulmonary disease
-
Larson RK, Barman ML. The familial occurrence of chronic obstructive pulmonary disease. Ann Intern Med 1965; 63:1001-8.
-
(1965)
Ann Intern Med
, vol.63
, pp. 1001-1008
-
-
Larson, R.K.1
Barman, M.L.2
-
7
-
-
0017800258
-
Studies of the familial aggregation of chronic bronchitis and obstructive airways disease
-
Tager I, Tishler PV, Rosner B, Speizer FE, Litt M. Studies of the familial aggregation of chronic bronchitis and obstructive airways disease. Int J Epidemiol 1978; 7:55-62.
-
(1978)
Int J Epidemiol
, vol.7
, pp. 55-62
-
-
Tager, I.1
Tishler, P.V.2
Rosner, B.3
Speizer, F.E.4
Litt, M.5
-
9
-
-
0035508452
-
Heritability of longitudinal change in lung function. The Framingham study
-
Gottlieb DJ, Wilk JB, Harmon M et al. Heritability of longitudinal change in lung function. The Framingham study. Am J Respir Crit Care Med 2001; 164:1655-9.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 1655-1659
-
-
Gottlieb, D.J.1
Wilk, J.B.2
Harmon, M.3
-
10
-
-
0021216876
-
Genetic and environmental determinants of level of pulmonary function
-
Lewitter FI, Tager IB, McGue M, Tishler PV, Speizer FE. Genetic and environmental determinants of level of pulmonary function. Am J Epidemiol 1984; 120:518-30.
-
(1984)
Am J Epidemiol
, vol.120
, pp. 518-530
-
-
Lewitter, F.I.1
Tager, I.B.2
McGue, M.3
Tishler, P.V.4
Speizer, F.E.5
-
11
-
-
0035021432
-
Familial aggregation and heritability of adult lung function: results from the Busselton Health Study
-
Palmer LJ, Knuiman MW, Divitini ML et al. Familial aggregation and heritability of adult lung function: results from the Busselton Health Study. Eur Respir J 2001; 17:696-702.
-
(2001)
Eur Respir J
, vol.17
, pp. 696-702
-
-
Palmer, L.J.1
Knuiman, M.W.2
Divitini, M.L.3
-
12
-
-
0033922390
-
Evidence for major genes influencing pulmonary function in the NHLBI family heart study
-
Wilk JB, Djousse L, Arnett DK et al. Evidence for major genes influencing pulmonary function in the NHLBI family heart study. Genet Epidemiol 2000; 19:81-94.
-
(2000)
Genet Epidemiol
, vol.19
, pp. 81-94
-
-
Wilk, J.B.1
Djousse, L.2
Arnett, D.K.3
-
13
-
-
24644460685
-
Key concepts in genetic epidemiology
-
Burton PR, Tobin MD, Hopper JL. Key concepts in genetic epidemiology. Lancet 2005; 366:941-51.
-
(2005)
Lancet
, vol.366
, pp. 941-951
-
-
Burton, P.R.1
Tobin, M.D.2
Hopper, J.L.3
-
14
-
-
18344392253
-
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease
-
Silverman EK, Palmer LJ, Mosley JD et al. Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease. Am J Hum Genet 2002; 70:1229-39.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1229-1239
-
-
Silverman, E.K.1
Palmer, L.J.2
Mosley, J.D.3
-
15
-
-
0038440501
-
Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease
-
Palmer LJ, Celedon JC, Chapman HA, Speizer FE, Weiss ST, Silverman EK. Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease. Hum Mol Genet 2003; 12:1199-210.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1199-1210
-
-
Palmer, L.J.1
Celedon, J.C.2
Chapman, H.A.3
Speizer, F.E.4
Weiss, S.T.5
Silverman, E.K.6
-
16
-
-
10644225206
-
Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease
-
DeMeo DL, Celedon JC, Lange C et al. Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2004; 170:1294-301.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1294-1301
-
-
DeMeo, D.L.1
Celedon, J.C.2
Lange, C.3
-
17
-
-
33747868403
-
The SERPINE2 gene is associated with chronic obstructive pulmonary disease
-
DeMeo D, Mariani T, Lange C et al. The SERPINE2 gene is associated with chronic obstructive pulmonary disease. Proc 2006; 3:502.
-
(2006)
Proc
, vol.3
, pp. 502
-
-
DeMeo, D.1
Mariani, T.2
Lange, C.3
-
18
-
-
34447315555
-
The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations
-
Zhu G, Warren L, Aponte J et al. The SERPINE2 gene is associated with chronic obstructive pulmonary disease in two large populations. Am J Respir Crit Care Med 2007; 176:167-73.
-
(2007)
Am J Respir Crit Care Med
, vol.176
, pp. 167-173
-
-
Zhu, G.1
Warren, L.2
Aponte, J.3
-
19
-
-
77956851757
-
The genetics of obstructive lung disease: big is beautiful
-
Hall IP, Lomas DA. The genetics of obstructive lung disease: big is beautiful. Thorax 2010; 65:760-1.
-
(2010)
Thorax
, vol.65
, pp. 760-761
-
-
Hall, I.P.1
Lomas, D.A.2
-
20
-
-
77949911882
-
The COPD genetic association compendium: a comprehensive online database of COPD genetic associations
-
Castaldi PJ, Cho MH, Cohn M et al. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. Hum Mol Genet 2010; 19:526-34.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 526-534
-
-
Castaldi, P.J.1
Cho, M.H.2
Cohn, M.3
-
21
-
-
70349449892
-
Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research
-
Smolonska J, Wijmenga C, Postma DS, Boezen HM. Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. Am J Respir Crit Care Med 2009; 180:618-31.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 618-631
-
-
Smolonska, J.1
Wijmenga, C.2
Postma, D.S.3
Boezen, H.M.4
-
22
-
-
79956307563
-
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample
-
Obeidat M, Wain LV, Shrine N et al. A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample. PLoS ONE 2011; 6:e19382.
-
(2011)
PLoS ONE
, vol.6
-
-
Obeidat, M.1
Wain, L.V.2
Shrine, N.3
-
23
-
-
79954523757
-
Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report
-
Silverman EK, Vestbo J, Agusti A et al. Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD 2011; 8:121-35.
-
(2011)
COPD
, vol.8
, pp. 121-135
-
-
Silverman, E.K.1
Vestbo, J.2
Agusti, A.3
-
24
-
-
33846563409
-
Why most published research findings are false
-
Ioannidis JP. Why most published research findings are false. PLoS Med 2005; 2:e124.
-
(2005)
PLoS Med
, vol.2
-
-
Ioannidis, J.P.1
-
25
-
-
1642295096
-
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004; 96:434-42.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
26
-
-
42349112088
-
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008; 9:356-69.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
-
27
-
-
84864004547
-
Genome-wide association studies in lung disease
-
Soler Artigas M, Wain LV, Tobin MD. Genome-wide association studies in lung disease. Thorax 2011; 2011:19.
-
(2011)
Thorax
, vol.2011
, pp. 19
-
-
Soler Artigas, M.1
Wain, L.V.2
Tobin, M.D.3
-
28
-
-
73349111257
-
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
-
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat Genet 2010; 42:45-52.
-
(2010)
Nat Genet
, vol.42
, pp. 45-52
-
-
Hancock, D.B.1
Eijgelsheim, M.2
Wilk, J.B.3
Gharib, S.A.4
Loehr, L.R.5
Marciante, K.D.6
-
29
-
-
73349143302
-
Genome-wide association study identifies five loci associated with lung function
-
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M et al. Genome-wide association study identifies five loci associated with lung function. Nat Genet 2010; 42:36-44.
-
(2010)
Nat Genet
, vol.42
, pp. 36-44
-
-
Repapi, E.1
Sayers, I.2
Wain, L.V.3
Burton, P.R.4
Johnson, T.5
Obeidat, M.6
-
30
-
-
77956331627
-
Integrating common and rare genetic variation in diverse human populations
-
Altshuler DM, Gibbs RA, Peltonen L et al. Integrating common and rare genetic variation in diverse human populations. Nature 2010; 467:52-8.
-
(2010)
Nature
, vol.467
, pp. 52-58
-
-
Altshuler, D.M.1
Gibbs, R.A.2
Peltonen, L.3
-
31
-
-
80055008094
-
Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function
-
Soler Artigas M, Loth DW, Wain LV et al. Genome-wide association and large scale follow-up identifies 16 new loci influencing lung function. Nat Genet 2011; 43:1082-90.
-
(2011)
Nat Genet
, vol.43
, pp. 1082-1090
-
-
Soler Artigas, M.1
Loth, D.W.2
Wain, L.V.3
-
32
-
-
63449099623
-
A genome-wide association study of pulmonary function measures in the Framingham Heart Study
-
Wilk JB, Chen TH, Gottlieb DJ et al. A genome-wide association study of pulmonary function measures in the Framingham Heart Study. PLoS Genet 2009; 5:e1000429.
-
(2009)
PLoS Genet
, vol.5
-
-
Wilk, J.B.1
Chen, T.H.2
Gottlieb, D.J.3
-
33
-
-
82755165236
-
The association of genome-wide significant spirometric loci with COPD susceptibility
-
Castaldi PJ, Cho MH, Litonjua AA et al. The association of genome-wide significant spirometric loci with COPD susceptibility. Am J Respir Cell Mol Biol 2011; 45:1147-53.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1147-1153
-
-
Castaldi, P.J.1
Cho, M.H.2
Litonjua, A.A.3
-
34
-
-
77649189442
-
Variants in FAM13A are associated with chronic obstructive pulmonary disease
-
Cho MH, Boutaoui N, Klanderman BJ et al. Variants in FAM13A are associated with chronic obstructive pulmonary disease. Nat Genet 2010; 42:200-2.
-
(2010)
Nat Genet
, vol.42
, pp. 200-202
-
-
Cho, M.H.1
Boutaoui, N.2
Klanderman, B.J.3
-
35
-
-
63449101907
-
A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci
-
Pillai SG, Ge D, Zhu G et al. A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci. PLoS Genet 2009; 5:e1000421.
-
(2009)
PLoS Genet
, vol.5
-
-
Pillai, S.G.1
Ge, D.2
Zhu, G.3
-
36
-
-
80053414310
-
Effect of 5 Genetic Variants Associated with Lung Function on the Risk of COPD, and their Joint Effects on Lung Function
-
Soler Artigas M, Wain LV, Repapi E et al. Effect of 5 Genetic Variants Associated with Lung Function on the Risk of COPD, and their Joint Effects on Lung Function. Am J Respir Crit Care Med 2011; 184:786-95.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 786-795
-
-
Soler Artigas, M.1
Wain, L.V.2
Repapi, E.3
-
37
-
-
44349142294
-
Common variants near MC4R are associated with fat mass, weight and risk of obesity
-
Loos RJ, Lindgren CM, Li S et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet 2008; 40:768-75.
-
(2008)
Nat Genet
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
Lindgren, C.M.2
Li, S.3
-
38
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen H, Estrada K, Lettre G et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467:832-8.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
-
39
-
-
0037477467
-
5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia
-
Manzke T, Guenther U, Ponimaskin EG et al. 5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia. Science 2003; 301:226-9.
-
(2003)
Science
, vol.301
, pp. 226-229
-
-
Manzke, T.1
Guenther, U.2
Ponimaskin, E.G.3
-
40
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 2009; 106:9362-7.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
-
41
-
-
40449092262
-
A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis
-
Englert JM, Hanford LE, Kaminski N et al. A role for the receptor for advanced glycation end products in idiopathic pulmonary fibrosis. Am J Pathol 2008; 172:583-91.
-
(2008)
Am J Pathol
, vol.172
, pp. 583-591
-
-
Englert, J.M.1
Hanford, L.E.2
Kaminski, N.3
-
42
-
-
4344689086
-
The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD)
-
Celedon JC, Lange C, Raby BA et al. The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD). Hum Mol Genet 2004; 13:1649-56.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1649-1656
-
-
Celedon, J.C.1
Lange, C.2
Raby, B.A.3
-
43
-
-
33645214183
-
Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease
-
Matheson MC, Ellis JA, Raven J, Walters EH, Abramson MJ. Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease. J Hum Genet 2006; 51:196-203.
-
(2006)
J Hum Genet
, vol.51
, pp. 196-203
-
-
Matheson, M.C.1
Ellis, J.A.2
Raven, J.3
Walters, E.H.4
Abramson, M.J.5
-
44
-
-
0035132050
-
Association of tumor necrosis factor alpha gene promoter polymorphism with the presence of chronic obstructive pulmonary disease
-
Sakao S, Tatsumi K, Igari H, Shino Y, Shirasawa H, Kuriyama T. Association of tumor necrosis factor alpha gene promoter polymorphism with the presence of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001; 163:420-2.
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 420-422
-
-
Sakao, S.1
Tatsumi, K.2
Igari, H.3
Shino, Y.4
Shirasawa, H.5
Kuriyama, T.6
-
45
-
-
33747114663
-
Decorin and TGF-beta1 polymorphisms and development of COPD in a general population
-
van Diemen CC, Postma DS, Vonk JM, Bruinenberg M, Nolte IM, Boezen HM. Decorin and TGF-beta1 polymorphisms and development of COPD in a general population. Respir Res 2006; 7:89.
-
(2006)
Respir Res
, vol.7
, pp. 89
-
-
van Diemen, C.C.1
Postma, D.S.2
Vonk, J.M.3
Bruinenberg, M.4
Nolte, I.M.5
Boezen, H.M.6
-
46
-
-
58949083626
-
Association of cytokine gene polymorphisms with rate of decline in lung function
-
Yucesoy B, Kurzius-Spencer M, Johnson VJ et al. Association of cytokine gene polymorphisms with rate of decline in lung function. J Occup Environ Med 2008; 50:642-8.
-
(2008)
J Occup Environ Med
, vol.50
, pp. 642-648
-
-
Yucesoy, B.1
Kurzius-Spencer, M.2
Johnson, V.J.3
-
47
-
-
72149129508
-
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma
-
Landi MT, Chatterjee N, Yu K et al. A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet 2009; 85:679-91.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 679-691
-
-
Landi, M.T.1
Chatterjee, N.2
Yu, K.3
-
48
-
-
67649777117
-
The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort
-
Kohansal R, Martinez-Camblor P, Agusti A, Buist AS, Mannino DM, Soriano JB. The natural history of chronic airflow obstruction revisited: an analysis of the Framingham offspring cohort. Am J Respir Crit Care Med 2009; 180:3-10.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 3-10
-
-
Kohansal, R.1
Martinez-Camblor, P.2
Agusti, A.3
Buist, A.S.4
Mannino, D.M.5
Soriano, J.B.6
-
49
-
-
35348898987
-
Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation
-
Morin C, Sirois M, Echave V, Gomes MM, Rousseau E. Functional effects of 20-HETE on human bronchi: hyperpolarization and relaxation due to BKCa channel activation. Am J Physiol Lung Cell Mol Physiol 2007; 293:L1037-44.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Morin, C.1
Sirois, M.2
Echave, V.3
Gomes, M.M.4
Rousseau, E.5
-
50
-
-
77956182127
-
Activation of endothelial BKCa channels causes pulmonary vasodilation
-
Vang A, Mazer J, Casserly B, Choudhary G. Activation of endothelial BKCa channels causes pulmonary vasodilation. Vascul Pharmacol 2010; 53:122-9.
-
(2010)
Vascul Pharmacol
, vol.53
, pp. 122-129
-
-
Vang, A.1
Mazer, J.2
Casserly, B.3
Choudhary, G.4
-
51
-
-
3042772969
-
DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites
-
Moriguchi T, Haraguchi K, Ueda N, Okada M, Furuya T, Akiyama T. DREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sites. Genes Cells 2004; 9:549-60.
-
(2004)
Genes Cells
, vol.9
, pp. 549-560
-
-
Moriguchi, T.1
Haraguchi, K.2
Ueda, N.3
Okada, M.4
Furuya, T.5
Akiyama, T.6
-
52
-
-
2942581287
-
Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma
-
Jongepier H, Boezen HM, Dijkstra A et al. Polymorphisms of the ADAM33 gene are associated with accelerated lung function decline in asthma. Clin Exp Allergy 2004; 34:757-60.
-
(2004)
Clin Exp Allergy
, vol.34
, pp. 757-760
-
-
Jongepier, H.1
Boezen, H.M.2
Dijkstra, A.3
-
53
-
-
22644432807
-
A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population
-
van Diemen CC, Postma DS, Vonk JM, Bruinenberg M, Schouten JP, Boezen HM. A disintegrin and metalloprotease 33 polymorphisms and lung function decline in the general population. Am J Respir Crit Care Med 2005; 172:329-33.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 329-333
-
-
van Diemen, C.C.1
Postma, D.S.2
Vonk, J.M.3
Bruinenberg, M.4
Schouten, J.P.5
Boezen, H.M.6
-
54
-
-
0037173639
-
Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
-
Van Eerdewegh P, Little RD, Dupuis J et al. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 2002; 418:426-30.
-
(2002)
Nature
, vol.418
, pp. 426-430
-
-
Van Eerdewegh, P.1
Little, R.D.2
Dupuis, J.3
-
55
-
-
0037678525
-
Retinoic acid signaling regulates murine bronchial tubule formation
-
Chazaud C, Dolle P, Rossant J, Mollard R. Retinoic acid signaling regulates murine bronchial tubule formation. Mech Dev 2003; 120:691-700.
-
(2003)
Mech Dev
, vol.120
, pp. 691-700
-
-
Chazaud, C.1
Dolle, P.2
Rossant, J.3
Mollard, R.4
-
56
-
-
0347079831
-
Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli
-
Massaro GD, Massaro D, Chan WY et al. Retinoic acid receptor-beta: an endogenous inhibitor of the perinatal formation of pulmonary alveoli. Physiol Genomics 2000; 4:51-7.
-
(2000)
Physiol Genomics
, vol.4
, pp. 51-57
-
-
Massaro, G.D.1
Massaro, D.2
Chan, W.Y.3
-
57
-
-
0037064591
-
Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet
-
Yang J, Liu X, Yue G, Adamian M, Bulgakov O, Li T. Rootletin, a novel coiled-coil protein, is a structural component of the ciliary rootlet. J Cell Biol 2002; 159:431-40.
-
(2002)
J Cell Biol
, vol.159
, pp. 431-440
-
-
Yang, J.1
Liu, X.2
Yue, G.3
Adamian, M.4
Bulgakov, O.5
Li, T.6
-
58
-
-
53149103590
-
Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells
-
Makrygiannakis D, Hermansson M, Ulfgren AK et al. Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann Rheum Dis 2008; 67:1488-92.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 1488-1492
-
-
Makrygiannakis, D.1
Hermansson, M.2
Ulfgren, A.K.3
-
59
-
-
70349083749
-
New and controversial therapies for chronic obstructive pulmonary disease
-
Bourbeau J, Johnson M. New and controversial therapies for chronic obstructive pulmonary disease. Proc 2009; 6:553-4.
-
(2009)
Proc
, vol.6
, pp. 553-554
-
-
Bourbeau, J.1
Johnson, M.2
-
60
-
-
21044458874
-
Decreased histone deacetylase activity in chronic obstructive pulmonary disease
-
Ito K, Ito M, Elliott WM et al. Decreased histone deacetylase activity in chronic obstructive pulmonary disease. N Engl J Med 2005; 352:1967-76.
-
(2005)
N Engl J Med
, vol.352
, pp. 1967-1976
-
-
Ito, K.1
Ito, M.2
Elliott, W.M.3
-
61
-
-
8344261349
-
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
-
Vega RB, Matsuda K, Oh J et al. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell 2004; 119:555-66.
-
(2004)
Cell
, vol.119
, pp. 555-566
-
-
Vega, R.B.1
Matsuda, K.2
Oh, J.3
-
63
-
-
79952901531
-
PM 2.5 collected in a residential area induced Th1-type inflammatory responses with oxidative stress in mice
-
Park EJ, Roh J, Kim Y, Park K, Kim DS, Yu SD. PM 2.5 collected in a residential area induced Th1-type inflammatory responses with oxidative stress in mice. Environ Res 2011; 111:348-55.
-
(2011)
Environ Res
, vol.111
, pp. 348-355
-
-
Park, E.J.1
Roh, J.2
Kim, Y.3
Park, K.4
Kim, D.S.5
Yu, S.D.6
-
64
-
-
0036501372
-
The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function
-
Joos L, He JQ, Shepherdson MB et al. The role of matrix metalloproteinase polymorphisms in the rate of decline in lung function. Hum Mol Genet 2002; 11:569-76.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 569-576
-
-
Joos, L.1
He, J.Q.2
Shepherdson, M.B.3
-
65
-
-
74049134939
-
MMP12, lung function, and COPD in high-risk populations
-
Hunninghake GM, Cho MH, Tesfaigzi Y et al. MMP12, lung function, and COPD in high-risk populations. N Engl J Med 2009; 361:2599-608.
-
(2009)
N Engl J Med
, vol.361
, pp. 2599-2608
-
-
Hunninghake, G.M.1
Cho, M.H.2
Tesfaigzi, Y.3
-
66
-
-
0035941048
-
Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema
-
Minematsu N, Nakamura H, Tateno H, Nakajima T, Yamaguchi K. Genetic polymorphism in matrix metalloproteinase-9 and pulmonary emphysema. Biochem Biophys Res Commun 2001; 289:116-19.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 116-119
-
-
Minematsu, N.1
Nakamura, H.2
Tateno, H.3
Nakajima, T.4
Yamaguchi, K.5
-
67
-
-
8844250037
-
Genetic polymorphism in matrix metalloproteinase-9 and the susceptibility to chronic obstructive pulmonary disease in Han population of south China
-
Zhou M, Huang SG, Wan HY, Li B, Deng WW, Li M. Genetic polymorphism in matrix metalloproteinase-9 and the susceptibility to chronic obstructive pulmonary disease in Han population of south China. Chin Med J (Engl) 2004; 117:1481-4.
-
(2004)
Chin Med J (Engl)
, vol.117
, pp. 1481-1484
-
-
Zhou, M.1
Huang, S.G.2
Wan, H.Y.3
Li, B.4
Deng, W.W.5
Li, M.6
-
68
-
-
0037322022
-
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?
-
Davey Smith G, Ebrahim S. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 2003; 32:1-22.
-
(2003)
Int J Epidemiol
, vol.32
, pp. 1-22
-
-
Davey Smith, G.1
Ebrahim, S.2
-
69
-
-
50949084462
-
Mendelian randomisation and causal inference in observational epidemiology
-
Sheehan NA, Didelez V, Burton PR, Tobin MD. Mendelian randomisation and causal inference in observational epidemiology. PLoS Med 2008; 5:e177.
-
(2008)
PLoS Med
, vol.5
-
-
Sheehan, N.A.1
Didelez, V.2
Burton, P.R.3
Tobin, M.D.4
-
70
-
-
77951751034
-
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
-
Liu JZ, Tozzi F, Waterworth DM et al. Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet 2010; 42:436-40.
-
(2010)
Nat Genet
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
-
71
-
-
77951748276
-
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
-
Thorgeirsson TE, Gudbjartsson DF, Surakka I et al. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet 2010; 42:448-53.
-
(2010)
Nat Genet
, vol.42
, pp. 448-453
-
-
Thorgeirsson, T.E.1
Gudbjartsson, D.F.2
Surakka, I.3
-
72
-
-
77951711343
-
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
-
Tobacco and Genetics Consortium.
-
Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet 2010; 42:441-7.
-
(2010)
Nat Genet
, vol.42
, pp. 441-447
-
-
-
73
-
-
70350512132
-
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene
-
DeMeo DL, Mariani T, Bhattacharya S et al. Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. Am J Hum Genet 2009; 85:493-502.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 493-502
-
-
DeMeo, D.L.1
Mariani, T.2
Bhattacharya, S.3
-
74
-
-
67650735159
-
Genomic copy number variation, human health, and disease
-
Wain LV, Armour JA, Tobin MD. Genomic copy number variation, human health, and disease. Lancet 2009; 374:340-50.
-
(2009)
Lancet
, vol.374
, pp. 340-350
-
-
Wain, L.V.1
Armour, J.A.2
Tobin, M.D.3
-
75
-
-
77949578084
-
Performance of common genetic variants in breast-cancer risk models
-
Wacholder S, Hartge P, Prentice R et al. Performance of common genetic variants in breast-cancer risk models. N Engl J Med 2010; 362:986-93.
-
(2010)
N Engl J Med
, vol.362
, pp. 986-993
-
-
Wacholder, S.1
Hartge, P.2
Prentice, R.3
-
76
-
-
76249109928
-
Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study
-
Talmud PJ, Hingorani AD, Cooper JA et al. Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study. BMJ 2010; 340:b4838.
-
(2010)
BMJ
, vol.340
-
-
Talmud, P.J.1
Hingorani, A.D.2
Cooper, J.A.3
-
77
-
-
33751236493
-
Developing COPD: a 25 year follow up study of the general population
-
Lokke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing COPD: a 25 year follow up study of the general population. Thorax 2006; 61:935-9.
-
(2006)
Thorax
, vol.61
, pp. 935-939
-
-
Lokke, A.1
Lange, P.2
Scharling, H.3
Fabricius, P.4
Vestbo, J.5
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