메뉴 건너뛰기




Volumn 6, Issue 12, 2011, Pages

Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; ALPHA SYNUCLEIN; BIOLOGICAL MARKER; ENDOTOXIN; LACTULOSE; LIPOPOLYSACCHARIDE BINDING PROTEIN; MANNITOL; SUCRALOSE; 3-NITROTYROSINE; ACUTE PHASE PROTEIN; CARRIER PROTEIN; DRUG DERIVATIVE; ENDOTOXIN, ESCHERICHIA COLI; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; SUCROSE; TRICHLOROSUCROSE; TYROSINE;

EID: 82455206282     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028032     Document Type: Article
Times cited : (698)

References (51)
  • 1
    • 66949152096 scopus 로고    scopus 로고
    • Parkinson's disease
    • Lees AJ, Hardy J, Revesz T, (2009) Parkinson's disease. Lancet 373: 2055-2066.
    • (2009) Lancet , vol.373 , pp. 2055-2066
    • Lees, A.J.1    Hardy, J.2    Revesz, T.3
  • 2
    • 33846572874 scopus 로고    scopus 로고
    • Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030
    • Dorsey ER, Constantinescu R, Thompson JP, Biglan KM, Holloway RG, et al. (2007) Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030. Neurology 68: 384-386.
    • (2007) Neurology , vol.68 , pp. 384-386
    • Dorsey, E.R.1    Constantinescu, R.2    Thompson, J.P.3    Biglan, K.M.4    Holloway, R.G.5
  • 3
    • 77958135785 scopus 로고    scopus 로고
    • The estimated life expectancy in a community cohort of Parkinson's disease patients with and without dementia, compared with the UK population
    • Hobson P, Meara J, Ishihara-Paul L, (2010) The estimated life expectancy in a community cohort of Parkinson's disease patients with and without dementia, compared with the UK population. J Neurol Neurosurg Psychiatry 81: 1093-1098.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 1093-1098
    • Hobson, P.1    Meara, J.2    Ishihara-Paul, L.3
  • 5
    • 43649106356 scopus 로고    scopus 로고
    • Invited Article: Nervous system pathology in sporadic Parkinson disease
    • Braak H, Del Tredici K, (2008) Invited Article: Nervous system pathology in sporadic Parkinson disease. Neurology 70: 1916-1925.
    • (2008) Neurology , vol.70 , pp. 1916-1925
    • Braak, H.1    Del Tredici, K.2
  • 6
    • 37349004102 scopus 로고    scopus 로고
    • Parkinson's disease
    • Thomas B, Beal MF, (2007) Parkinson's disease. Hum Mol Genet 16 Spec No. 2: R183-194.
    • (2007) Hum Mol Genet , vol.16 , Issue.2
    • Thomas, B.1    Beal, M.F.2
  • 8
    • 34447554529 scopus 로고    scopus 로고
    • Starring roles for astroglia in barrier pathologies of gut and brain
    • Savidge TC, Sofroniew MV, Neunlist M, (2007) Starring roles for astroglia in barrier pathologies of gut and brain. Lab Invest 87: 731-736.
    • (2007) Lab Invest , vol.87 , pp. 731-736
    • Savidge, T.C.1    Sofroniew, M.V.2    Neunlist, M.3
  • 9
  • 10
    • 77950669604 scopus 로고    scopus 로고
    • The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice
    • Turnbaugh PJ, Ridaura VK, Faith JJ, Rey FE, Knight R, et al. (2009) The effect of diet on the human gut microbiome: a metagenomic analysis in humanized gnotobiotic mice. Sci Transl Med 1: 6ra14.
    • (2009) Sci Transl Med , vol.1
    • Turnbaugh, P.J.1    Ridaura, V.K.2    Faith, J.J.3    Rey, F.E.4    Knight, R.5
  • 11
    • 77951468091 scopus 로고    scopus 로고
    • Multiple facets of intestinal permeability and epithelial handling of dietary antigens
    • Menard S, Cerf-Bensussan N, Heyman M, (2010) Multiple facets of intestinal permeability and epithelial handling of dietary antigens. Mucosal Immunol 3: 247-259.
    • (2010) Mucosal Immunol , vol.3 , pp. 247-259
    • Menard, S.1    Cerf-Bensussan, N.2    Heyman, M.3
  • 14
    • 0038748401 scopus 로고    scopus 로고
    • Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
    • Braak H, Rub U, Gai WP, Del Tredici K, (2003) Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J Neural Transm 110: 517-536.
    • (2003) J Neural Transm , vol.110 , pp. 517-536
    • Braak, H.1    Rub, U.2    Gai, W.P.3    Del Tredici, K.4
  • 16
    • 0034773027 scopus 로고    scopus 로고
    • Dual role of lipopolysaccharide (LPS)-binding protein in neutralization of LPS and enhancement of LPS-induced activation of mononuclear cells
    • Gutsmann T, Muller M, Carroll SF, MacKenzie RC, Wiese A, et al. (2001) Dual role of lipopolysaccharide (LPS)-binding protein in neutralization of LPS and enhancement of LPS-induced activation of mononuclear cells. Infect Immun 69: 6942-6950.
    • (2001) Infect Immun , vol.69 , pp. 6942-6950
    • Gutsmann, T.1    Muller, M.2    Carroll, S.F.3    MacKenzie, R.C.4    Wiese, A.5
  • 17
    • 0028924539 scopus 로고
    • Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14
    • Tobias PS, Soldau K, Gegner JA, Mintz D, Ulevitch RJ, (1995) Lipopolysaccharide binding protein-mediated complexation of lipopolysaccharide with soluble CD14. J Biol Chem 270: 10482-10488.
    • (1995) J Biol Chem , vol.270 , pp. 10482-10488
    • Tobias, P.S.1    Soldau, K.2    Gegner, J.A.3    Mintz, D.4    Ulevitch, R.J.5
  • 18
    • 58249105899 scopus 로고    scopus 로고
    • LPS-binding protein mediates LPS-induced liver injury and mortality in the setting of biliary obstruction
    • Minter RM, Bi X, Ben-Josef G, Wang T, Hu B, et al. (2009) LPS-binding protein mediates LPS-induced liver injury and mortality in the setting of biliary obstruction. Am J Physiol Gastrointest Liver Physiol 296: G45-54.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Minter, R.M.1    Bi, X.2    Ben-Josef, G.3    Wang, T.4    Hu, B.5
  • 20
    • 67349122370 scopus 로고    scopus 로고
    • Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease
    • Greene JG, Noorian AR, Srinivasan S, (2009) Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease. Exp Neurol 218: 154-161.
    • (2009) Exp Neurol , vol.218 , pp. 154-161
    • Greene, J.G.1    Noorian, A.R.2    Srinivasan, S.3
  • 21
    • 0023186176 scopus 로고
    • Parkinson's disease and megacolon: concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells
    • Kupsky WJ, Grimes MM, Sweeting J, Bertsch R, Cote LJ, (1987) Parkinson's disease and megacolon: concentric hyaline inclusions (Lewy bodies) in enteric ganglion cells. Neurology 37: 1253-1255.
    • (1987) Neurology , vol.37 , pp. 1253-1255
    • Kupsky, W.J.1    Grimes, M.M.2    Sweeting, J.3    Bertsch, R.4    Cote, L.J.5
  • 22
    • 0021161884 scopus 로고
    • Esophageal Lewy bodies associated with ganglion cell loss in achalasia. Similarity to Parkinson's disease
    • Qualman SJ, Haupt HM, Yang P, Hamilton SR, (1984) Esophageal Lewy bodies associated with ganglion cell loss in achalasia. Similarity to Parkinson's disease. Gastroenterology 87: 848-856.
    • (1984) Gastroenterology , vol.87 , pp. 848-856
    • Qualman, S.J.1    Haupt, H.M.2    Yang, P.3    Hamilton, S.R.4
  • 23
    • 0023805080 scopus 로고
    • Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses
    • Wakabayashi K, Takahashi H, Takeda S, Ohama E, Ikuta F, (1988) Parkinson's disease: the presence of Lewy bodies in Auerbach's and Meissner's plexuses. Acta Neuropathol 76: 217-221.
    • (1988) Acta Neuropathol , vol.76 , pp. 217-221
    • Wakabayashi, K.1    Takahashi, H.2    Takeda, S.3    Ohama, E.4    Ikuta, F.5
  • 24
    • 0025346316 scopus 로고
    • Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system
    • Wakabayashi K, Takahashi H, Ohama E, Ikuta F, (1990) Parkinson's disease: an immunohistochemical study of Lewy body-containing neurons in the enteric nervous system. Acta Neuropathol 79: 581-583.
    • (1990) Acta Neuropathol , vol.79 , pp. 581-583
    • Wakabayashi, K.1    Takahashi, H.2    Ohama, E.3    Ikuta, F.4
  • 25
    • 0030662269 scopus 로고    scopus 로고
    • Neuropathology of autonomic nervous system in Parkinson's disease
    • Wakabayashi K, Takahashi H, (1997) Neuropathology of autonomic nervous system in Parkinson's disease. Eur Neurol 38 (Suppl 2): 2-7.
    • (1997) Eur Neurol , vol.38 , Issue.SUPPL. 2 , pp. 2-7
    • Wakabayashi, K.1    Takahashi, H.2
  • 26
    • 56549121613 scopus 로고    scopus 로고
    • Pathological lesions in colonic biopsies during Parkinson's disease
    • Lebouvier T, Chaumette T, Damier P, Coron E, Touchefeu Y, et al. (2008) Pathological lesions in colonic biopsies during Parkinson's disease. Gut 57: 1741-1743.
    • (2008) Gut , vol.57 , pp. 1741-1743
    • Lebouvier, T.1    Chaumette, T.2    Damier, P.3    Coron, E.4    Touchefeu, Y.5
  • 27
    • 77958558412 scopus 로고    scopus 로고
    • Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms
    • Lebouvier T, Neunlist M, Bruley des Varannes S, Coron E, Drouard A, et al. (2010) Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms. PLoS One 5: e12728.
    • (2010) PLoS One , vol.5
    • Lebouvier, T.1    Neunlist, M.2    des Bruley Varannes, S.3    Coron, E.4    Drouard, A.5
  • 28
    • 41149110768 scopus 로고    scopus 로고
    • Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?
    • Phillips RJ, Walter GC, Wilder SL, Baronowsky EA, Powley TL, (2008) Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease? Neuroscience 153: 733-750.
    • (2008) Neuroscience , vol.153 , pp. 733-750
    • Phillips, R.J.1    Walter, G.C.2    Wilder, S.L.3    Baronowsky, E.A.4    Powley, T.L.5
  • 30
    • 62549133546 scopus 로고    scopus 로고
    • Neuroinflammation in Parkinson's disease: a target for neuroprotection?
    • Hirsch EC, Hunot S, (2009) Neuroinflammation in Parkinson's disease: a target for neuroprotection? Lancet Neurol 8: 382-397.
    • (2009) Lancet Neurol , vol.8 , pp. 382-397
    • Hirsch, E.C.1    Hunot, S.2
  • 31
    • 71849087424 scopus 로고    scopus 로고
    • Neuroinflammation in the living brain of Parkinson's disease
    • Ouchi Y, Yagi S, Yokokura M, Sakamoto M, (2009) Neuroinflammation in the living brain of Parkinson's disease. Parkinsonism Relat Disord 15 (Suppl 3): S200-204.
    • (2009) Parkinsonism Relat Disord , vol.15 , Issue.SUPPL. 3
    • Ouchi, Y.1    Yagi, S.2    Yokokura, M.3    Sakamoto, M.4
  • 32
    • 14944352071 scopus 로고    scopus 로고
    • Inflammation and the degenerative diseases of aging
    • McGeer PL, McGeer EG, (2004) Inflammation and the degenerative diseases of aging. Ann N Y Acad Sci 1035: 104-116.
    • (2004) Ann N Y Acad Sci , vol.1035 , pp. 104-116
    • McGeer, P.L.1    McGeer, E.G.2
  • 33
    • 0037734163 scopus 로고    scopus 로고
    • Endotoxin: is it an environmental factor in the cause of Parkinson's disease?
    • Niehaus I, Lange JH, (2003) Endotoxin: is it an environmental factor in the cause of Parkinson's disease? Occup Environ Med 60: 378.
    • (2003) Occup Environ Med , vol.60 , pp. 378
    • Niehaus, I.1    Lange, J.H.2
  • 34
    • 33847759064 scopus 로고    scopus 로고
    • Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
    • Qin L, Wu X, Block ML, Liu Y, Breese GR, et al. (2007) Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 55: 453-462.
    • (2007) Glia , vol.55 , pp. 453-462
    • Qin, L.1    Wu, X.2    Block, M.L.3    Liu, Y.4    Breese, G.R.5
  • 35
    • 62949177919 scopus 로고    scopus 로고
    • Dopaminergic and serotoninergic deficiencies in young adult rats prenatally exposed to the bacterial lipopolysaccharide
    • Wang S, Yan JY, Lo YK, Carvey PM, Ling Z, (2009) Dopaminergic and serotoninergic deficiencies in young adult rats prenatally exposed to the bacterial lipopolysaccharide. Brain Res 1265: 196-204.
    • (2009) Brain Res , vol.1265 , pp. 196-204
    • Wang, S.1    Yan, J.Y.2    Lo, Y.K.3    Carvey, P.M.4    Ling, Z.5
  • 36
    • 34247366072 scopus 로고    scopus 로고
    • Inflammation as a causative factor in the aetiology of Parkinson's disease
    • Whitton PS, (2007) Inflammation as a causative factor in the aetiology of Parkinson's disease. Br J Pharmacol 150: 963-976.
    • (2007) Br J Pharmacol , vol.150 , pp. 963-976
    • Whitton, P.S.1
  • 37
    • 25444474430 scopus 로고    scopus 로고
    • Modulatory effects of sCD14 and LBP on LPS-host cell interactions
    • Kitchens RL, Thompson PA, (2005) Modulatory effects of sCD14 and LBP on LPS-host cell interactions. J Endotoxin Res 11: 225-229.
    • (2005) J Endotoxin Res , vol.11 , pp. 225-229
    • Kitchens, R.L.1    Thompson, P.A.2
  • 38
    • 79955536232 scopus 로고    scopus 로고
    • Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells
    • Keck S, Muller I, Fejer G, Savic I, Tchaptchet S, et al. (2011) Absence of TRIF Signaling in Lipopolysaccharide-Stimulated Murine Mast Cells. J Immunol 186: 5478-5488.
    • (2011) J Immunol , vol.186 , pp. 5478-5488
    • Keck, S.1    Muller, I.2    Fejer, G.3    Savic, I.4    Tchaptchet, S.5
  • 39
    • 0034663061 scopus 로고    scopus 로고
    • Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia
    • Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, et al. (2000) Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia. J Neurosci 20: 6309-6316.
    • (2000) J Neurosci , vol.20 , pp. 6309-6316
    • Kim, W.G.1    Mohney, R.P.2    Wilson, B.3    Jeohn, G.H.4    Liu, B.5
  • 40
    • 79955921784 scopus 로고    scopus 로고
    • Neuroinflammation and alpha-Synuclein Dysfunction Potentiate Each Other Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease
    • Gao HM, Zhang F, Zhou H, Kam W, Wilson B, et al. (2011) Neuroinflammation and alpha-Synuclein Dysfunction Potentiate Each Other Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease. Environ Health Perspect.
    • (2011) Environ Health Perspect
    • Gao, H.M.1    Zhang, F.2    Zhou, H.3    Kam, W.4    Wilson, B.5
  • 41
    • 70349666893 scopus 로고    scopus 로고
    • Increased mucosal nitric oxide production in ulcerative colitis is mediated in part by the enteroglial-derived S100B protein
    • Cirillo C, Sarnelli G, Esposito G, Grosso M, Petruzzelli R, et al. (2009) Increased mucosal nitric oxide production in ulcerative colitis is mediated in part by the enteroglial-derived S100B protein. Neurogastroenterol Motil 21: 1209-e1112.
    • (2009) Neurogastroenterol Motil , vol.21
    • Cirillo, C.1    Sarnelli, G.2    Esposito, G.3    Grosso, M.4    Petruzzelli, R.5
  • 42
    • 65849441307 scopus 로고    scopus 로고
    • Lipopolysaccharides enhance the action of bradykinin in enteric neurons via secretion of interleukin-1beta from enteric glial cells
    • Murakami M, Ohta T, Ito S, (2009) Lipopolysaccharides enhance the action of bradykinin in enteric neurons via secretion of interleukin-1beta from enteric glial cells. J Neurosci Res 87: 2095-2104.
    • (2009) J Neurosci Res , vol.87 , pp. 2095-2104
    • Murakami, M.1    Ohta, T.2    Ito, S.3
  • 43
    • 58149279447 scopus 로고    scopus 로고
    • Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS)
    • Zhang R, Miller RG, Gascon R, Champion S, Katz J, et al. (2009) Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS). J Neuroimmunol 206: 121-124.
    • (2009) J Neuroimmunol , vol.206 , pp. 121-124
    • Zhang, R.1    Miller, R.G.2    Gascon, R.3    Champion, S.4    Katz, J.5
  • 44
    • 42149093127 scopus 로고    scopus 로고
    • The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression
    • Maes M, Kubera M, Leunis JC, (2008) The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression. Neuro Endocrinol Lett 29: 117-124.
    • (2008) Neuro Endocrinol Lett , vol.29 , pp. 117-124
    • Maes, M.1    Kubera, M.2    Leunis, J.C.3
  • 46
    • 0029914203 scopus 로고    scopus 로고
    • Intestinal permeability and orocaecal transit time in elderly patients with Parkinson's disease
    • Davies KN, King D, Billington D, Barrett JA, (1996) Intestinal permeability and orocaecal transit time in elderly patients with Parkinson's disease. Postgrad Med J 72: 164-167.
    • (1996) Postgrad Med J , vol.72 , pp. 164-167
    • Davies, K.N.1    King, D.2    Billington, D.3    Barrett, J.A.4
  • 47
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
    • Hughes AJ, Daniel SE, Kilford L, Lees AJ, (1992) Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55: 181-184.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4
  • 48
    • 77649300234 scopus 로고    scopus 로고
    • Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults
    • McOmber ME, Ou CN, Shulman RJ, (2010) Effects of timing, sex, and age on site-specific gastrointestinal permeability testing in children and adults. J Pediatr Gastroenterol Nutr 50: 269-275.
    • (2010) J Pediatr Gastroenterol Nutr , vol.50 , pp. 269-275
    • McOmber, M.E.1    Ou, C.N.2    Shulman, R.J.3
  • 49
    • 33646597781 scopus 로고    scopus 로고
    • Resolution of common dietary sugars from probe sugars for test of intestinal permeability using capillary column gas chromatography
    • Farhadi A, Keshavarzian A, Fields JZ, Sheikh M, Banan A, (2006) Resolution of common dietary sugars from probe sugars for test of intestinal permeability using capillary column gas chromatography. J Chromatogr B Analyt Technol Biomed Life Sci 836: 63-68.
    • (2006) J Chromatogr B Analyt Technol Biomed Life Sci , vol.836 , pp. 63-68
    • Farhadi, A.1    Keshavarzian, A.2    Fields, J.Z.3    Sheikh, M.4    Banan, A.5
  • 50
    • 0037464608 scopus 로고    scopus 로고
    • Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability
    • Farhadi A, Keshavarzian A, Holmes EW, Fields J, Zhang L, et al. (2003) Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability. J Chromatogr B Analyt Technol Biomed Life Sci 784: 145-154.
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.784 , pp. 145-154
    • Farhadi, A.1    Keshavarzian, A.2    Holmes, E.W.3    Fields, J.4    Zhang, L.5
  • 51
    • 77958083540 scopus 로고    scopus 로고
    • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
    • Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, et al. (2010) Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. PLoS Pathog 6.
    • (2010) PLoS Pathog , vol.6
    • Estes, J.D.1    Harris, L.D.2    Klatt, N.R.3    Tabb, B.4    Pittaluga, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.