Beta-lactam antibiotic reduces morphine analgesic tolerance in rats through GLT-1 transporter activation

Drug and Alcohol Dependence

Volumn 107, Issue 2-3, 2010, Pages 261-263

  Rawls, Scott M ^a   Zielinski, Michael ^a   Patel, Hiren ^a   Sacavage, Steven ^a   Baron, David A ^a   Patel, Digvesh ^a  

^a Temple University Health Sciences Center   (United States)

Author keywords

Beta lactam antibiotic; Ceftriaxone; GLT 1; Glutamate; Morphine; Opioid; Tolerance

Indexed keywords

CEFTRIAXONE; MORPHINE SULFATE; VESICULAR GLUTAMATE TRANSPORTER 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG COMPETITION; DRUG EFFICACY; DRUG MECHANISM; HOT PLATE TEST; MALE; MORNING DOSAGE; MORPHINE ADDICTION; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALGESICS, OPIOID; ANIMALS; ANTI-BACTERIAL AGENTS; CEFTRIAXONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; EXCITATORY AMINO ACID TRANSPORTER 2; HOT TEMPERATURE; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SUBCUTANEOUS; KAINIC ACID; MALE; MORPHINE; PAIN MEASUREMENT; PAIN THRESHOLD; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME;

RATTUS;

EID: 77649191179     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.10.010     Document Type: Article

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