Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a Sertoli-cell-only syndrome-like phenotype in mice

Biology of Reproduction

Volumn 79, Issue 4, 2008, Pages 598-607

  Million Passe, Christina M ^a   White, Crystal R ^b   King, Michael W ^c   Quirk, Phillip L ^b   Iovanna, Juan L ^d   Quirk, Christine C ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c Indiana University   (United States)

^d INSERM   (France)

Author keywords

Gonadotroph; Luteinizing hormone; NUPR1; Ovary; p8; Pituitary; Sertoli cell only syndrome; Testis

Indexed keywords

GONADOTROPIN; LUTEINIZING HORMONE BETA SUBUNIT; MESSENGER RNA; NUCLEAR PROTEIN; PEPTIDE HORMONE; PROTEIN NUPR1; PROTEIN P2; THYROTROPIN; TRANSCRIPTION FACTOR GATA 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GERM CELL; GONADOTROPIN SECRETING CELL; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; OVARY DEVELOPMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; SERTOLI CELL; SERTOLI CELL ONLY SYNDROME; SEXUAL MATURATION; SEXUAL MATURITY; TESTIS DEVELOPMENT; TESTIS DISEASE;

ANIMALS; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; FEMALE; FOLLICLE STIMULATING HORMONE, BETA SUBUNIT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GONADOTROPHS; LUTEINIZING HORMONE, BETA SUBUNIT; MALE; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; OVARY; PITUITARY GLAND; SERTOLI CELL-ONLY SYNDROME; SEXUAL MATURATION; TESTIS; TISSUE DISTRIBUTION;

MUS;

EID: 53349171466     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.108.068304     Document Type: Article

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