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Volumn 26, Issue 4, 2006, Pages 515-521

Minocycline for short-term neuroprotection

Author keywords

Minocycline; Neuroprotection; Stroke

Indexed keywords

LIVER ENZYME; MINOCYCLINE; NITROGEN; UREA;

EID: 33645662983     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.26.4.515     Document Type: Article
Times cited : (158)

References (55)
  • 1
    • 0034989884 scopus 로고    scopus 로고
    • Targeting the central nervous system inflammatory response in ischemic stroke
    • Becker KJ. Targeting the central nervous system inflammatory response in ischemic stroke. Curr Opin Neurol 2001;14:349-53.
    • (2001) Curr Opin Neurol , vol.14 , pp. 349-353
    • Becker, K.J.1
  • 2
    • 0035106674 scopus 로고    scopus 로고
    • Current status and perspectives of neuroprotection in ischemic stroke treatment
    • Martinez-Vila E, Sieria PI. Current status and perspectives of neuroprotection in ischemic stroke treatment. Cerebrovasc Dis 2001;11(suppl 1):60-70.
    • (2001) Cerebrovasc Dis , vol.11 , Issue.SUPPL. 1 , pp. 60-70
    • Martinez-Vila, E.1    Sieria, P.I.2
  • 3
    • 0033787273 scopus 로고    scopus 로고
    • Neuroprotection
    • Lees KR. Neuroprotection. Br Med Bull 2000;56:401-12.
    • (2000) Br Med Bull , vol.56 , pp. 401-412
    • Lees, K.R.1
  • 4
    • 0034008372 scopus 로고    scopus 로고
    • Why do neuroprotective drugs work in animals but not humans?
    • DeGraba TJ, Pettigrew LC. Why do neuroprotective drugs work in animals but not humans? Neurol Clin 2000;18(2):475-93.
    • (2000) Neurol Clin , vol.18 , Issue.2 , pp. 475-493
    • DeGraba, T.J.1    Pettigrew, L.C.2
  • 5
    • 0031984137 scopus 로고    scopus 로고
    • Neuroprotection as initial therapy in acute stroke. Third report of an ad hoc consensus group meeting
    • The European ad hoc consensus group
    • Anonymous. Neuroprotection as initial therapy in acute stroke. Third report of an ad hoc consensus group meeting. The European ad hoc consensus group. Cerebrovasc Dis 1998;8(1):59-72.
    • (1998) Cerebrovasc Dis , vol.8 , Issue.1 , pp. 59-72
  • 6
    • 0036330007 scopus 로고    scopus 로고
    • Toward wisdom from failure: Lessons from neuroprotective stroke trials and new therapeutic directions
    • Gladstone DJ, Black SE, Hakim AM. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 2002;33:2123-36.
    • (2002) Stroke , vol.33 , pp. 2123-2136
    • Gladstone, D.J.1    Black, S.E.2    Hakim, A.M.3
  • 7
    • 0032198174 scopus 로고    scopus 로고
    • Chemical and biological dynamics of tetracyclines
    • Nelson ML, Chemical and biological dynamics of tetracyclines. Adv Dent Res 1998;12:5-11.
    • (1998) Adv Dent Res , vol.12 , pp. 5-11
    • Nelson, M.L.1
  • 8
    • 0017280436 scopus 로고
    • Acne: Treatment with minocycline
    • Coskey RJ. Acne: treatment with minocycline. Cutis 1976;17(4):799-801.
    • (1976) Cutis , vol.17 , Issue.4 , pp. 799-801
    • Coskey, R.J.1
  • 9
    • 33645675185 scopus 로고    scopus 로고
    • MD Consult Web page
    • MD Consult Web page. Minocycline HCl. Available from www.mdconsult.com. Accessed June 20, 2005.
    • Minocycline HCl
  • 10
    • 0011970183 scopus 로고    scopus 로고
    • Antimicrobial agents: Protein synthesis inhibitors and miscellaneous antibacterial agents
    • Hardman JG, Limbird LE, Gilman AG, eds. New York: McGraw-Hill Professional
    • Chambers HF. Antimicrobial agents: protein synthesis inhibitors and miscellaneous antibacterial agents. In: Hardman JG, Limbird LE, Gilman AG, eds. Goodman & Gilman's the pharmacological basis of therapeutics, 10th ed. New York: McGraw-Hill Professional, 2001:1240-6.
    • (2001) Goodman & Gilman's the Pharmacological Basis of Therapeutics, 10th Ed. , pp. 1240-1246
    • Chambers, H.F.1
  • 11
    • 0023245356 scopus 로고
    • A non-antibacterial chemically modified tetracycline inhibits mammalian collagenase activity
    • Golub LM, McNamara TF, d'Angelo GD, Greenwald RA, Ramamurthy NS. A non-antibacterial chemically modified tetracycline inhibits mammalian collagenase activity. J Dent Res 1987;66:1310-14.
    • (1987) J Dent Res , vol.66 , pp. 1310-1314
    • Golub, L.M.1    McNamara, T.F.2    D'Angelo, G.D.3    Greenwald, R.A.4    Ramamurthy, N.S.5
  • 12
    • 0026018690 scopus 로고
    • Suppression of human neutrophil functions by tetracyclines
    • Gabler WL, Creamer HR. Suppression of human neutrophil functions by tetracyclines. J Periodontal Res 1991;26:52-8.
    • (1991) J Periodontal Res , vol.26 , pp. 52-58
    • Gabler, W.L.1    Creamer, H.R.2
  • 13
    • 0028888687 scopus 로고
    • Minocycline in rheumatoid arthritis: A 48-week, double-blinded, placebo-controlled trial
    • Tilley BC, Alarcon GS, Heyse SP, et al. Minocycline in rheumatoid arthritis: a 48-week, double-blinded, placebo-controlled trial. Ann Intern Med 1995;122:81-9.
    • (1995) Ann Intern Med , vol.122 , pp. 81-89
    • Tilley, B.C.1    Alarcon, G.S.2    Heyse, S.P.3
  • 14
    • 0033539522 scopus 로고    scopus 로고
    • A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemic with a wide therapeutic window
    • Yrjänheikki J, Tikka T, Keinänen R, Goldsteins G. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemic with a wide therapeutic window. Proc Natl Acad Sci U S A 1999;96:13496-500.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 13496-13500
    • Yrjänheikki, J.1    Tikka, T.2    Keinänen, R.3    Goldsteins, G.4
  • 15
    • 0013071212 scopus 로고    scopus 로고
    • Delayed minocycline but not delayed mild hypothermia protects against embolic stroke
    • Wang CX, Yang T, Noor R, Shuaib A. Delayed minocycline but not delayed mild hypothermia protects against embolic stroke. Biomed Cent Neurol 2002;2:2-8.
    • (2002) Biomed Cent Neurol , vol.2 , pp. 2-8
    • Wang, C.X.1    Yang, T.2    Noor, R.3    Shuaib, A.4
  • 16
    • 18144393838 scopus 로고    scopus 로고
    • Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage
    • Morimoto N, Shimazawa M, Yamashima T, Nagabi H, Hara H. Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage. Brain Res 2005;1044:8-15.
    • (2005) Brain Res , vol.1044 , pp. 8-15
    • Morimoto, N.1    Shimazawa, M.2    Yamashima, T.3    Nagabi, H.4    Hara, H.5
  • 17
    • 2642545055 scopus 로고    scopus 로고
    • Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
    • Xu L, Fagan SC, Waller JL, et al. Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats [online exclusive article]. BMC Neurol 2004;4:7. Available from www.biomedcentral.com/1471-2377/4/7.
    • (2004) BMC Neurol , vol.4 , pp. 7
    • Xu, L.1    Fagan, S.C.2    Waller, J.L.3
  • 19
    • 0036289498 scopus 로고    scopus 로고
    • Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury
    • Arvin KL, Han BH, Du Y, Lin S, Paul SM, Holtzman DM. Minocycline markedly protects the neonatal brain against hypoxic-ischemic injury. Ann Neurol 2002;52:54-61.
    • (2002) Ann Neurol , vol.52 , pp. 54-61
    • Arvin, K.L.1    Han, B.H.2    Du, Y.3    Lin, S.4    Paul, S.M.5    Holtzman, D.M.6
  • 20
    • 1542376941 scopus 로고    scopus 로고
    • Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury
    • Stirling DP, Khodarahmi K, Liu J, et al. Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury. J Neurosci 2004;24:2182-90.
    • (2004) J Neurosci , vol.24 , pp. 2182-2190
    • Stirling, D.P.1    Khodarahmi, K.2    Liu, J.3
  • 21
    • 12144290904 scopus 로고    scopus 로고
    • Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
    • Teng YD, Choi H, Onario RC, et al. Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. Proc Natl Acad Sci U S A 2004;101:3071-6.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3071-3076
    • Teng, Y.D.1    Choi, H.2    Onario, R.C.3
  • 22
    • 0037481943 scopus 로고    scopus 로고
    • Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice
    • Wells JEA, Hurlbert RJ, Fehlings MG, Yong VW. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain 2003;126:1628-37.
    • (2003) Brain , vol.126 , pp. 1628-1637
    • Wells, J.E.A.1    Hurlbert, R.J.2    Fehlings, M.G.3    Yong, V.W.4
  • 23
    • 0034998271 scopus 로고    scopus 로고
    • Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction
    • Sanchez Mejia RO, Ona VO, Li M, Friedlander RM. Minocycline reduces traumatic brain injury-mediated caspase-1 activation, tissue damage, and neurological dysfunction. Neurosurgery 2001;48:1393-401.
    • (2001) Neurosurgery , vol.48 , pp. 1393-1401
    • Sanchez Mejia, R.O.1    Ona, V.O.2    Li, M.3    Friedlander, R.M.4
  • 24
    • 0038443057 scopus 로고    scopus 로고
    • Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases
    • Power C, Henry S, Del Bigio MR, et al. Intracerebral hemorrhage induces macrophage activation and matrix metalloproteinases. Ann Neurol 2003;53:731-42.
    • (2003) Ann Neurol , vol.53 , pp. 731-742
    • Power, C.1    Henry, S.2    Del Bigio, M.R.3
  • 25
    • 0037435882 scopus 로고    scopus 로고
    • Effects of minocycline alone and in combination with mild hypothermia in embolic stroke
    • Wang CX, Yang T, Schuaib A. Effects of minocycline alone and in combination with mild hypothermia in embolic stroke. Brain Res 2003;963:327-9.
    • (2003) Brain Res , vol.963 , pp. 327-329
    • Wang, C.X.1    Yang, T.2    Schuaib, A.3
  • 26
    • 0024271676 scopus 로고
    • Clinical pharmacokinetics of doxycycline and minocycline
    • Saivin S, Hovin G. Clinical pharmacokinetics of doxycycline and minocycline. Clin Pharmacokinet 1988;15:355-66.
    • (1988) Clin Pharmacokinet , vol.15 , pp. 355-366
    • Saivin, S.1    Hovin, G.2
  • 27
  • 28
    • 0030450402 scopus 로고    scopus 로고
    • A novel mechanism of action of tetracyclines: Effects of nitric oxide synthases
    • Amin AR, Attur MG, Thakker GD, et al. A novel mechanism of action of tetracyclines: effects of nitric oxide synthases. Proc Natl Acad Sci U S A 1996;93:14014-19.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14014-14019
    • Amin, A.R.1    Attur, M.G.2    Thakker, G.D.3
  • 29
    • 7244242682 scopus 로고    scopus 로고
    • Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia coculture
    • Lee SM, Yune TY, Kim SJ, et al. Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia coculture. J Neurochem 2004;91:568-78.
    • (2004) J Neurochem , vol.91 , pp. 568-578
    • Lee, S.M.1    Yune, T.Y.2    Kim, S.J.3
  • 30
    • 0035807904 scopus 로고    scopus 로고
    • Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease
    • Du Y, Ma Z, Lin S, et al. Minocycline prevents nigrostriatal dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Pro Natl Acad Sci U S A 2001;98:14669-74.
    • (2001) Pro Natl Acad Sci U S A , vol.98 , pp. 14669-14674
    • Du, Y.1    Ma, Z.2    Lin, S.3
  • 31
    • 0036260089 scopus 로고    scopus 로고
    • Targeting leukocyte MMPs and transmigration: Minocycline as a potential therapy for multiple sclerosis
    • Brundula V, Rewcastle NB, Metz LM, Bernard CC, Yong VW. Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis. Brain 2002;125(pt 6):1297-308.
    • (2002) Brain , vol.125 , Issue.PART 6 , pp. 1297-1308
    • Brundula, V.1    Rewcastle, N.B.2    Metz, L.M.3    Bernard, C.C.4    Yong, V.W.5
  • 32
    • 0035871840 scopus 로고    scopus 로고
    • Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
    • Tikka T, Fiebich BL, Goldsteins G, Keinanen R, Koistinaho J. Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia. J Neurosci 2001;21:2580-8.
    • (2001) J Neurosci , vol.21 , pp. 2580-2588
    • Tikka, T.1    Fiebich, B.L.2    Goldsteins, G.3    Keinanen, R.4    Koistinaho, J.5
  • 33
    • 0035940779 scopus 로고    scopus 로고
    • Minocycline blocks nitric oxide-induced neurotoxicity by inhibition of p38 MAPK in rat cerebellar granule neurons
    • Lin S, Zhang Y, Dodel R, Farlow MR, Paul SM, Du Y. Minocycline blocks nitric oxide-induced neurotoxicity by inhibition of p38 MAPK in rat cerebellar granule neurons. Neurosci Lett 2001;315:61-4.
    • (2001) Neurosci Lett , vol.315 , pp. 61-64
    • Lin, S.1    Zhang, Y.2    Dodel, R.3    Farlow, M.R.4    Paul, S.M.5    Du, Y.6
  • 34
    • 0031917042 scopus 로고    scopus 로고
    • Update on clinical trials in the rheumatic diseases
    • Furst DE. Update on clinical trials in the rheumatic diseases, Curr Opin Rheumatol 1998;10:123-8.
    • (1998) Curr Opin Rheumatol , vol.10 , pp. 123-128
    • Furst, D.E.1
  • 35
    • 0034761723 scopus 로고    scopus 로고
    • Treatment of early seropositive rheumatoid arthritis: A two year double-blind comparison of minocycline and hydroxychloroquine
    • O'Dell JR, Blakely KW, Mallek JA, et al. Treatment of early seropositive rheumatoid arthritis: a two year double-blind comparison of minocycline and hydroxychloroquine. Arthritis Rheum 2001;44:2235-41.
    • (2001) Arthritis Rheum , vol.44 , pp. 2235-2241
    • O'Dell, J.R.1    Blakely, K.W.2    Mallek, J.A.3
  • 36
    • 11144354138 scopus 로고    scopus 로고
    • Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis
    • Metz LM, Zhang Y, Yeung M, et al. Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis [letter]. Ann Neurol 2004;55:756.
    • (2004) Ann Neurol , vol.55 , pp. 756
    • Metz, L.M.1    Zhang, Y.2    Yeung, M.3
  • 37
    • 0037007645 scopus 로고    scopus 로고
    • Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
    • Zhu S, Stavrovskaya IG, Drozda M, et al. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature 2002;417:74-8.
    • (2002) Nature , vol.417 , pp. 74-78
    • Zhu, S.1    Stavrovskaya, I.G.2    Drozda, M.3
  • 38
    • 0041335559 scopus 로고    scopus 로고
    • Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease
    • Wang X, Zhu S, Drozda M, et al. Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease. Pro Natl Acad Sci USA 2003;100:10483-7.
    • (2003) Pro Natl Acad Sci USA , vol.100 , pp. 10483-10487
    • Wang, X.1    Zhu, S.2    Drozda, M.3
  • 39
    • 2442454612 scopus 로고    scopus 로고
    • Minocycline upregulates Bcl-2 and protects against cell death in mitochondria
    • Wang J, Wei Q, Wang C, Hill WD, Hess DC, Dong Z. Minocycline upregulates Bcl-2 and protects against cell death in mitochondria. J Biol Chem 2004;279:19948-54.
    • (2004) J Biol Chem , vol.279 , pp. 19948-19954
    • Wang, J.1    Wei, Q.2    Wang, C.3    Hill, W.D.4    Hess, D.C.5    Dong, Z.6
  • 40
    • 33645694677 scopus 로고    scopus 로고
    • Minocycline protects neurons, but not astrocytes against oxygen glucose deprivation via apoptotic pathway
    • Matsukawa N, Yasuhara T, Xu L, et al. Minocycline protects neurons, but not astrocytes against oxygen glucose deprivation via apoptotic pathway [abstr]. Exp Neurol 2005;193:253.
    • (2005) Exp Neurol , vol.193 , pp. 253
    • Matsukawa, N.1    Yasuhara, T.2    Xu, L.3
  • 41
    • 10744226569 scopus 로고    scopus 로고
    • Minocycline inhibits caspase activation and reactivation, increases the ratio of X1AP to smac/Diablo, and reduces the mitochondrial leakage of cytochrome C and smac/Diablo
    • Scarabelli TM, Stephanou A, Pasini E, et al. Minocycline inhibits caspase activation and reactivation, increases the ratio of X1AP to smac/Diablo, and reduces the mitochondrial leakage of cytochrome C and smac/Diablo. J Am Coll Cardiol 2004;43(5):865-74.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.5 , pp. 865-874
    • Scarabelli, T.M.1    Stephanou, A.2    Pasini, E.3
  • 42
    • 0027292516 scopus 로고
    • Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: A potential therapeutic role for tetracyclines and their chemically-modified analogs
    • Rifkin BR, Vernillo AT, Golub LM. Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs. J Periodontol 1993;64(8 suppl):819-27.
    • (1993) J Periodontol , vol.64 , Issue.8 SUPPL. , pp. 819-827
    • Rifkin, B.R.1    Vernillo, A.T.2    Golub, L.M.3
  • 43
    • 0032837039 scopus 로고    scopus 로고
    • Clinical trials of a matrix metalloproteinase inhibitor in human periodontal disease: SDD clinical research team
    • Ashley RA. Clinical trials of a matrix metalloproteinase inhibitor in human periodontal disease: SDD clinical research team. Ann N Y Acad Sci 1999;878:335-46.
    • (1999) Ann N Y Acad Sci , vol.878 , pp. 335-346
    • Ashley, R.A.1
  • 44
    • 0026643124 scopus 로고
    • Tetracyclines suppress matrix metalloproteinase activity in adjuvant arthritis and in combination with flurbiprofen, ameliorate bone damage
    • Greenwald RA, Moak SA, Eamamurthy NS, Golub LM. Tetracyclines suppress matrix metalloproteinase activity in adjuvant arthritis and in combination with flurbiprofen, ameliorate bone damage. J Rheumatol 1992;19(6):927-38.
    • (1992) J Rheumatol , vol.19 , Issue.6 , pp. 927-938
    • Greenwald, R.A.1    Moak, S.A.2    Eamamurthy, N.S.3    Golub, L.M.4
  • 47
    • 0034192486 scopus 로고    scopus 로고
    • Advances in the vascular pathophysiology of ischemic stroke
    • del Zoppo GJ, Hallenbeck JM. Advances in the vascular pathophysiology of ischemic stroke. Thromb Res 2000;98(3):73-81.
    • (2000) Thromb Res , vol.98 , Issue.3 , pp. 73-81
    • Del Zoppo, G.J.1    Hallenbeck, J.M.2
  • 49
    • 0035800589 scopus 로고    scopus 로고
    • Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum
    • He Y, Appel S, Le W. Minocycline inhibits microglial activation and protects nigral cells after 6-hydroxydopamine injection into mouse striatum. Brain Res 2001;909:187-93.
    • (2001) Brain Res , vol.909 , pp. 187-193
    • He, Y.1    Appel, S.2    Le, W.3
  • 50
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu DC, Jackson-Lewis V, Vila M, et al. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J Neurosci 2002;22:1763-71.
    • (2002) J Neurosci , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3
  • 51
    • 1542722933 scopus 로고    scopus 로고
    • Optimal delivery of minocycline to the brain: Implication for human studies of acute neuroprotection
    • Fagan SC, Edwards DJ, Borlongan C, et al. Optimal delivery of minocycline to the brain: implication for human studies of acute neuroprotection. Exp Neurol 2004;186:248-51.
    • (2004) Exp Neurol , vol.186 , pp. 248-251
    • Fagan, S.C.1    Edwards, D.J.2    Borlongan, C.3
  • 52
    • 0038359549 scopus 로고    scopus 로고
    • Liquid Chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat
    • Colovic M, Caccia S. Liquid Chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat. J Chrom B 2003;791:337-43.
    • (2003) J Chrom B , vol.791 , pp. 337-343
    • Colovic, M.1    Caccia, S.2
  • 53
    • 0017283596 scopus 로고
    • Minocycline for prophylaxis of infection with Neisseria meningitides: High rate of side effects in recipients
    • Drew TJ, Altman R, Black K, Goldfield M. Minocycline for prophylaxis of infection with Neisseria meningitides: high rate of side effects in recipients. J Infect Dis 1976;133:194-8.
    • (1976) J Infect Dis , vol.133 , pp. 194-198
    • Drew, T.J.1    Altman, R.2    Black, K.3    Goldfield, M.4
  • 54
    • 2442715084 scopus 로고    scopus 로고
    • Placebo controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis
    • Gordon PH, Moore DH, Gelinas DF, et al. Placebo controlled phase I/II studies of minocycline in amyotrophic lateral sclerosis. Neurology 2004;62:1845-7.
    • (2004) Neurology , vol.62 , pp. 1845-1847
    • Gordon, P.H.1    Moore, D.H.2    Gelinas, D.F.3
  • 55
    • 0016283936 scopus 로고
    • Minocycline administered intravenously: Pharmacological activity and clinical experience
    • Clark BJ, Hodgson CR, Dornbush AC, Hutchinson J. Minocycline administered intravenously: pharmacological activity and clinical experience. Curr Ther Res 1974;16:865-77.
    • (1974) Curr Ther Res , vol.16 , pp. 865-877
    • Clark, B.J.1    Hodgson, C.R.2    Dornbush, A.C.3    Hutchinson, J.4


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