-
1
-
-
0011964662
-
Tumor class prediction and discovery by microarray-based DNA methylation analysis
-
Adorjan P, Distler J, Lipscher E, Model F, Muller J, Pelet C, Braun A, Florl AR, Gutig D, Grabs G et al (2002) Tumor class prediction and discovery by microarray-based DNA methylation analysis. Nucleic Acids Res 30: e21.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Adorjan, P.1
Distler, J.2
Lipscher, E.3
Model, F.4
Muller, J.5
Pelet, C.6
Braun, A.7
Florl, A.R.8
Gutig, D.9
Grabs, G.10
-
2
-
-
0032401808
-
Aging and DNA methylation in colorectal mucosa and cancer
-
Ahuja N, Li Q, Mohan AL, Baylin SB, Issa JP (1998) Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 58: 5489-5494.
-
(1998)
Cancer Res
, vol.58
, pp. 5489-5494
-
-
Ahuja, N.1
Li, Q.2
Mohan, A.L.3
Baylin, S.B.4
Issa, J.P.5
-
3
-
-
0142182088
-
Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells
-
Akiyama Y, Maesawa C, Ogasawara S, Terashima M, Masuda T (2003) Cell-type-specific repression of the maspin gene is disrupted frequently by demethylation at the promoter region in gastric intestinal metaplasia and cancer cells. Am J Pathol 163: 1911-1919.
-
(2003)
Am J Pathol
, vol.163
, pp. 1911-1919
-
-
Akiyama, Y.1
Maesawa, C.2
Ogasawara, S.3
Terashima, M.4
Masuda, T.5
-
4
-
-
77954644767
-
DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas
-
Amara K, Ziadi S, Hachana M, Soltani N, Korbi S, Trimeche M (2010) DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas. Cancer Sci 101: 1722-1730.
-
(2010)
Cancer Sci
, vol.101
, pp. 1722-1730
-
-
Amara, K.1
Ziadi, S.2
Hachana, M.3
Soltani, N.4
Korbi, S.5
Trimeche, M.6
-
6
-
-
33748600947
-
mat-/- mice leads to a differentiation defect in the extraembryonic tissue
-
mat-/- mice leads to a differentiation defect in the extraembryonic tissue. Dev Biol 297: 361-373.
-
(2006)
Dev Biol
, vol.297
, pp. 361-373
-
-
Arima, T.1
Hata, K.2
Tanaka, S.3
Kusumi, M.4
Li, E.5
Kato, K.6
Shiota, K.7
Sasaki, H.8
Wake, N.9
-
7
-
-
67449100703
-
Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus
-
Baba S, Yamada Y, Hatano Y, Miyazaki Y, Mori H, Shibata T, Hara A (2009) Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus. Cancer Sci 100: 1186-1191.
-
(2009)
Cancer Sci
, vol.100
, pp. 1186-1191
-
-
Baba, S.1
Yamada, Y.2
Hatano, Y.3
Miyazaki, Y.4
Mori, H.5
Shibata, T.6
Hara, A.7
-
8
-
-
0038365277
-
CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimen: Genomic hypomethylation correlates with carcinogenic progression
-
Badal V, Chuang LS, Tan EH, Badal S, Villa LL, Wheeler CM, Li BF, Bernard HU (2003) CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimen: genomic hypomethylation correlates with carcinogenic progression. J Virol 77: 6227-6234.
-
(2003)
J Virol
, vol.77
, pp. 6227-6234
-
-
Badal, V.1
Chuang, L.S.2
Tan, E.H.3
Badal, S.4
Villa, L.L.5
Wheeler, C.M.6
Li, B.F.7
Bernard, H.U.8
-
9
-
-
24744453331
-
Methyl-CpG-binding proteins in cancer: Blaming the DNA methylation messenger
-
Ballestar E, Esteller M (2005) Methyl-CpG-binding proteins in cancer: blaming the DNA methylation messenger. Biochem Cell Biol 83: 374-384.
-
(2005)
Biochem Cell Biol
, vol.83
, pp. 374-384
-
-
Ballestar, E.1
Esteller, M.2
-
10
-
-
33644846509
-
Epigenetic gene silencing in cancer: A mechanism for early oncogenic pathway addiction?
-
Baylin SB, Ohm JE (2006) Epigenetic gene silencing in cancer: a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6: 107-116.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
11
-
-
0022495317
-
DNA methylation patterns of the calcitonin gene in human lung cancers and lymphomas
-
Baylin SB, Hoppener JW, de Bustros A, Steenbergh PH, Lips CJ, Nelkin BD (1986) DNA methylation patterns of the calcitonin gene in human lung cancers and lymphomas. Cancer Res 46: 2917-2922.
-
(1986)
Cancer Res
, vol.46
, pp. 2917-2922
-
-
Baylin, S.B.1
Hoppener, J.W.2
de Bustros, A.3
Steenbergh, P.H.4
Lips, C.J.5
Nelkin, B.D.6
-
12
-
-
0030006213
-
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer
-
Belinsky SA, Nikula KJ, Baylin SB, Issa JP (1996) Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer. Proc Natl Acad Sci USA 93: 4045-4050.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4045-4050
-
-
Belinsky, S.A.1
Nikula, K.J.2
Baylin, S.B.3
Issa, J.P.4
-
13
-
-
0032578509
-
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
Belinsky SA, Nikulan KJ, Palmisano WA, Michels R, Saccomanno G, Gabrielson E, Baylin SB, Herman JG (1998) Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA 95: 11891-11896.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikulan, K.J.2
Palmisano, W.A.3
Michels, R.4
Saccomanno, G.5
Gabrielson, E.6
Baylin, S.B.7
Herman, J.G.8
-
14
-
-
77649104794
-
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
-
Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM (2010) Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463: 1042-1047.
-
(2010)
Nature
, vol.463
, pp. 1042-1047
-
-
Bhutani, N.1
Brady, J.J.2
Damian, M.3
Sacco, A.4
Corbel, S.Y.5
Blau, H.M.6
-
15
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
16
-
-
0033601073
-
Methylation-induced repression-Belts, braces, and chromatin
-
Bird AP, Wolffe AP (1999) Methylation-induced repression-Belts, braces, and chromatin. Cell 99: 451-454.
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
17
-
-
69249220176
-
DNA methylation and methyl-CpG binding proteins: Developmental requirements and functions
-
Bogdanović O, Veenstra GJ (2009) DNA methylation and methyl-CpG binding proteins: developmental requirements and functions. Chromosoma 118: 549-565.
-
(2009)
Chromosoma
, vol.118
, pp. 549-565
-
-
Bogdanović, O.1
Veenstra, G.J.2
-
18
-
-
0035930660
-
Dnmt3L and the establishment of maternal genomic imprints
-
Bourc'his C, Xu GL, Lin CS, Bollman B, Bestor TH (2001) Dnmt3L and the establishment of maternal genomic imprints. Science 294: 2536-2539.
-
(2001)
Science
, vol.294
, pp. 2536-2539
-
-
Bourc'his, C.1
Xu, G.L.2
Lin, C.S.3
Bollman, B.4
Bestor, T.H.5
-
19
-
-
0036607452
-
DNA methyltransferases get connected to chromatin
-
Burgers WA, Fuks F, Kouzarides T (2002) DNA methyltransferases get connected to chromatin. Trends Genet 18: 275-277.
-
(2002)
Trends Genet
, vol.18
, pp. 275-277
-
-
Burgers, W.A.1
Fuks, F.2
Kouzarides, T.3
-
20
-
-
65449144773
-
The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: Results from the GMALL study group
-
Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, Schneider B, Raff T, Reinhardt R, Gökbuget N et al (2009) The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group. Blood 113: 4011-4015.
-
(2009)
Blood
, vol.113
, pp. 4011-4015
-
-
Burmeister, T.1
Meyer, C.2
Schwartz, S.3
Hofmann, J.4
Molkentin, M.5
Kowarz, E.6
Schneider, B.7
Raff, T.8
Reinhardt, R.9
Gökbuget, N.10
-
21
-
-
0344630574
-
Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene
-
Buschhausen G, Wittig B, Graessmann M, Graessmann A (1987) Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 84: 1177-1181.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 1177-1181
-
-
Buschhausen, G.1
Wittig, B.2
Graessmann, M.3
Graessmann, A.4
-
22
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB (1999) Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21: 103-107.
-
(1999)
Nat Genet
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
Bachman, K.E.2
Myohanen, S.3
Herman, J.G.4
Baylin, S.B.5
-
23
-
-
33748103002
-
Genetic variants in epigenetic genes and breast cancer risk
-
Cebrian A, Pharoah PD, Ahmed S, Ropero S, Fraga MF, Smith PL, Conroy D, Luben R, Perkins B, Easton DF et al (2006) Genetic variants in epigenetic genes and breast cancer risk. Carcinogenesis 27: 1661-1669.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1661-1669
-
-
Cebrian, A.1
Pharoah, P.D.2
Ahmed, S.3
Ropero, S.4
Fraga, M.F.5
Smith, P.L.6
Conroy, D.7
Luben, R.8
Perkins, B.9
Easton, D.F.10
-
24
-
-
77957878987
-
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine
-
Champion C, Guianvarc'h D, Senamaud-Beaufort C, Jurkowska RZ, Jeltsch A, Ponger L, Arimondo PB, Guieysse-Peugeot AL (2010) Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine. PLoS One 5: e12388.
-
(2010)
PLoS One
, vol.5
-
-
Champion, C.1
Guianvarc'h, D.2
Senamaud-Beaufort, C.3
Jurkowska, R.Z.4
Jeltsch, A.5
Ponger, L.6
Arimondo, P.B.7
Guieysse-Peugeot, A.L.8
-
25
-
-
31144434402
-
DNA hypermethylation of promoter of gene p53 and p16 in arsenicexposed people with and without malignancy
-
Chanda S, Dasgupta UB, Guhamazumder D, Gupta M, Chaudhuri U, Lahiri S, Das S, Ghosh N, Chatterjee D (2006) DNA hypermethylation of promoter of gene p53 and p16 in arsenicexposed people with and without malignancy. Toxicol Sci 89: 431-437.
-
(2006)
Toxicol Sci
, vol.89
, pp. 431-437
-
-
Chanda, S.1
Dasgupta, U.B.2
Guhamazumder, D.3
Gupta, M.4
Chaudhuri, U.5
Lahiri, S.6
Das, S.7
Ghosh, N.8
Chatterjee, D.9
-
26
-
-
58949094559
-
Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells
-
Chatagnon A, Bougel S, Perriaud L, Lachuer J, Benhattar J, Dante R (2009) Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells. Carcinogenesis 30: 28-34.
-
(2009)
Carcinogenesis
, vol.30
, pp. 28-34
-
-
Chatagnon, A.1
Bougel, S.2
Perriaud, L.3
Lachuer, J.4
Benhattar, J.5
Dante, R.6
-
27
-
-
0037168587
-
The DNA methyltransferases-like protein DNMT3L stimulates de novo methylation by Dnmt3a
-
Chedin F, Lieber MR, Hsieh CL (2002) The DNA methyltransferases-like protein DNMT3L stimulates de novo methylation by Dnmt3a. Proc Natl Acad Sci USA 99: 16916-16921.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16916-16921
-
-
Chedin, F.1
Lieber, M.R.2
Hsieh, C.L.3
-
28
-
-
5144228492
-
Preferential response of cancer cells to zebularine
-
Cheng JC, Yoo CB, Weisenberger DJ, Chuang J, Wozniak C, Liang G, Marquez VE, Greer S, Orntoft TF, Thykjaer T, Jones PA (2004) Preferential response of cancer cells to zebularine. Cancer Cell 6: 151-158.
-
(2004)
Cancer Cell
, vol.6
, pp. 151-158
-
-
Cheng, J.C.1
Yoo, C.B.2
Weisenberger, D.J.3
Chuang, J.4
Wozniak, C.5
Liang, G.6
Marquez, V.E.7
Greer, S.8
Orntoft, T.F.9
Thykjaer, T.10
Jones, P.A.11
-
29
-
-
0035902856
-
Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma
-
Cho M, Uemura H, Kim SC, Kawada Y, Yoshida K, Hirao Y, Konishi N, Saga S, Yoshikawa K (2001) Hypomethylation of the MN/CA9 promoter and upregulated MN/CA9 expression in human renal cell carcinoma. Br J Cancer 85: 563-567.
-
(2001)
Br J Cancer
, vol.85
, pp. 563-567
-
-
Cho, M.1
Uemura, H.2
Kim, S.C.3
Kawada, Y.4
Yoshida, K.5
Hirao, Y.6
Konishi, N.7
Saga, S.8
Yoshikawa, K.9
-
30
-
-
77955787215
-
Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients
-
Cho YH, Yazici H, Wu HC, Terry MB, Gonzalez K, Qu M, Dalay N, Santella RM (2010) Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients. Anticancer Res 30: 2489-2496.
-
(2010)
Anticancer Res
, vol.30
, pp. 2489-2496
-
-
Cho, Y.H.1
Yazici, H.2
Wu, H.C.3
Terry, M.B.4
Gonzalez, K.5
Qu, M.6
Dalay, N.7
Santella, R.M.8
-
31
-
-
77952203695
-
S110, a 5-aza-2ʹ-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth
-
Chuang JC, Warner SL, Vollmer D, Vankayalapati H, Redkar S, Bearss DJ, Qiu X, Yoo CB, Jones PA (2010) S110, a 5-aza-2ʹ-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Mol Cancer Ther 9: 1443-1450.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1443-1450
-
-
Chuang, J.C.1
Warner, S.L.2
Vollmer, D.3
Vankayalapati, H.4
Redkar, S.5
Bearss, D.J.6
Qiu, X.7
Yoo, C.B.8
Jones, P.A.9
-
32
-
-
34547765951
-
Action at a distance: Epigenetic silencing of large chromosomal regions in carcinogenesis
-
Clark SJ (2007) Action at a distance: epigenetic silencing of large chromosomal regions in carcinogenesis. Hum Mol Genet 16(Spec No 1): R88-R95.
-
(2007)
Hum Mol Genet
, vol.16
, pp. R88-R95
-
-
Clark, S.J.1
-
33
-
-
0043026893
-
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix
-
Cohen Y, Singer G, Lavie O, Dong SM, Beller U, Sidransky D (2003) The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix. Clin Cancer Res 9: 2981-2984.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2981-2984
-
-
Cohen, Y.1
Singer, G.2
Lavie, O.3
Dong, S.M.4
Beller, U.5
Sidransky, D.6
-
34
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420: 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
35
-
-
79952034429
-
UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer
-
Dadkalos A, Oleksiewicz U, Filia A, Nikolaidis G, Xinarianos G, Gosney JR, Malliri A, Field JK, Liloglou T (2011) UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer. Cancer 117: 1027-1037.
-
(2011)
Cancer
, vol.117
, pp. 1027-1037
-
-
Dadkalos, A.1
Oleksiewicz, U.2
Filia, A.3
Nikolaidis, G.4
Xinarianos, G.5
Gosney, J.R.6
Malliri, A.7
Field, J.K.8
Liloglou, T.9
-
36
-
-
79955004702
-
Advances in DNA methylation: 5-hydroxymethylcytosine revisited
-
Dahl C, Grønbæk K, Guldberg P (2011) Advances in DNA methylation: 5-hydroxymethylcytosine revisited. Clin Chim Acta. doi: 10. 1016/j. cca. 2011. 02. 013.
-
(2011)
Clin Chim Acta
-
-
Dahl, C.1
Grønbæk, K.2
Guldberg, P.3
-
37
-
-
74549162340
-
Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma
-
Dammann RH, Kirsch S, Schagdarsurengin U, Dansranjavin T, Gradhand E, Schmitt WD, Hauptmann S (2010) Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma. Int J Oncol 36: 171-179.
-
(2010)
Int J Oncol
, vol.36
, pp. 171-179
-
-
Dammann, R.H.1
Kirsch, S.2
Schagdarsurengin, U.3
Dansranjavin, T.4
Gradhand, E.5
Schmitt, W.D.6
Hauptmann, S.7
-
38
-
-
73349128157
-
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines
-
Dandrea M, Donadelli M, Costanzo C, Scarpa A, Palmieri M (2009) MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. Nucleic Acids Res 37: 6681-6690.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 6681-6690
-
-
Dandrea, M.1
Donadelli, M.2
Costanzo, C.3
Scarpa, A.4
Palmieri, M.5
-
39
-
-
0037376690
-
Biochemical fractionation reveals association of DNA methyltransferase (Dnmt)3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1
-
Datta J, Ghoshal K, Sharma SM, Tajima S, Jacob ST (2003) Biochemical fractionation reveals association of DNA methyltransferase (Dnmt)3b with Dnmt1 and that of Dnmt 3a with a histone H3 methyltransferase and Hdac1. J Cell Biochem 88: 855-864.
-
(2003)
J Cell Biochem
, vol.88
, pp. 855-864
-
-
Datta, J.1
Ghoshal, K.2
Sharma, S.M.3
Tajima, S.4
Jacob, S.T.5
-
40
-
-
0642345170
-
DNA demethylation is directly related to tumor progression: Evidence in normal, pre-malignant and malignant cells from uterine cervix samples
-
De Capoa A, Musolino A, Della Rosa S, Caiafa P, Mariani L, Del Nonno F, Vocaturo A, Donnorso RP, Niveleau A, Grappelli C (2003) DNA demethylation is directly related to tumor progression: evidence in normal, pre-malignant and malignant cells from uterine cervix samples. Oncol Rep 10: 545-549.
-
(2003)
Oncol Rep
, vol.10
, pp. 545-549
-
-
De Capoa, A.1
Musolino, A.2
Della Rosa, S.3
Caiafa, P.4
Mariani, L.5
Del Nonno, F.6
Vocaturo, A.7
Donnorso, R.P.8
Niveleau, A.9
Grappelli, C.10
-
41
-
-
0033566973
-
Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
-
De Marzo AM, Marchi VL, Yang ES, Veeraswamy R, Lin X, Nelson WG (1999) Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res 59: 3855-3860.
-
(1999)
Cancer Res
, vol.59
, pp. 3855-3860
-
-
De Marzo, A.M.1
Marchi, V.L.2
Yang, E.S.3
Veeraswamy, R.4
Lin, X.5
Nelson, W.G.6
-
42
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C et al (2002) Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 295: 1079-1082.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
Raker, V.A.2
Corsaro, M.3
Fazi, F.4
Fanelli, M.5
Faretta, M.6
Fuks, F.7
Lo Coco, F.8
Kouzarides, T.9
Nervi, C.10
-
43
-
-
76249131823
-
DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences
-
Diede SJ, Guenthoer J, Geng LN, Mahoney SE, Marotta M, Olson JM, Tanaka H, Tapscott SJ (2010) DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences. Proc Natl Acad Sci USA 107: 234-239.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 234-239
-
-
Diede, S.J.1
Guenthoer, J.2
Geng, L.N.3
Mahoney, S.E.4
Marotta, M.5
Olson, J.M.6
Tanaka, H.7
Tapscott, S.J.8
-
44
-
-
24044481947
-
Inactivation of Dnmt3b in mouse embryonicfibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization
-
Dodge JE, Okano M, Dick F, Tsujimoto N, Chen T, Wang S, Ueda Y, Dyson N, Li E (2005) Inactivation of Dnmt3b in mouse embryonicfibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization. J Biol Chem 280: 17986-17991.
-
(2005)
J Biol Chem
, vol.280
, pp. 17986-17991
-
-
Dodge, J.E.1
Okano, M.2
Dick, F.3
Tsujimoto, N.4
Chen, T.5
Wang, S.6
Ueda, Y.7
Dyson, N.8
Li, E.9
-
45
-
-
0037083647
-
Regulation of stage-specific nuclear translocation of Dnmt1o during preimplantation mouse development
-
Doherty AS, Bartolomei MS, Schultz RM (2002) Regulation of stage-specific nuclear translocation of Dnmt1o during preimplantation mouse development. Dev Biol 242: 255-266.
-
(2002)
Dev Biol
, vol.242
, pp. 255-266
-
-
Doherty, A.S.1
Bartolomei, M.S.2
Schultz, R.M.3
-
46
-
-
0019198357
-
Mutagenic deamination of cytosine residues in DNA
-
Duncan BK, Miller JH (1980) Mutagenic deamination of cytosine residues in DNA. Nature 287: 560-561.
-
(1980)
Nature
, vol.287
, pp. 560-561
-
-
Duncan, B.K.1
Miller, J.H.2
-
47
-
-
0026329756
-
Breast cancer genetic evolution: Data from cytogenetics and DNA content
-
Dutrillaux B, Gerbault-Seureau M, Remvikos Y, Zafrani B, Prieur M (1991) Breast cancer genetic evolution: data from cytogenetics and DNA content. Breast Cancer Res Treat 193: 245-255.
-
(1991)
Breast Cancer Res Treat
, vol.193
, pp. 245-255
-
-
Dutrillaux, B.1
Gerbault-Seureau, M.2
Remvikos, Y.3
Zafrani, B.4
Prieur, M.5
-
48
-
-
0036494563
-
Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice
-
Eads CA, Nickel AE, Laird PW (2002) Complete genetic suppression of polyp formation and reduction of CpG-island hypermethylation in Apc(Min/+) Dnmt1-hypomorphic Mice. Cancer Res 62: 1296-1299.
-
(2002)
Cancer Res
, vol.62
, pp. 1296-1299
-
-
Eads, C.A.1
Nickel, A.E.2
Laird, P.W.3
-
49
-
-
0242584454
-
Chromosomal instability and tumors promoted by DNA hypomethylation
-
Eden A, Gaudet F, Waghmare A, Jaenisch R (2003) Chromosomal instability and tumors promoted by DNA hypomethylation. Science 300: 455.
-
(2003)
Science
, vol.300
-
-
Eden, A.1
Gaudet, F.2
Waghmare, A.3
Jaenisch, R.4
-
50
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429: 457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
51
-
-
77954661906
-
DNA hypomethylation in cancer cells
-
Ehrlich M (2009) DNA hypomethylation in cancer cells. Epigenomics 1: 239-259.
-
(2009)
Epigenomics
, vol.1
, pp. 239-259
-
-
Ehrlich, M.1
-
52
-
-
78651348687
-
Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers
-
Endo Y, Marusawa H, Chiba T (2011) Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers. J Gastroenterol 46(Suppl 1): 6-10.
-
(2011)
J Gastroenterol
, vol.46
, pp. 6-10
-
-
Endo, Y.1
Marusawa, H.2
Chiba, T.3
-
53
-
-
13844320649
-
Aberrant DNA methylation as a cancer-inducing mechanism
-
Esteller M (2005) Aberrant DNA methylation as a cancer-inducing mechanism. Annu Rev Pharmacol Toxicol 45: 629-656.
-
(2005)
Annu Rev Pharmacol Toxicol
, vol.45
, pp. 629-656
-
-
Esteller, M.1
-
54
-
-
33745602221
-
The necessity of a human epigenome project
-
Esteller M (2006) The necessity of a human epigenome project. Carcinogenesis 27: 1121-1125.
-
(2006)
Carcinogenesis
, vol.27
, pp. 1121-1125
-
-
Esteller, M.1
-
55
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M (2007) Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8: 286-298.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
56
-
-
67651119885
-
Single nucleotide polymorphism in DNMT3B promoter and its association with hepatocellular carcinoma in a Moroccan population
-
Ezzikouri S, El Feydi AE, Benazzouz M, Afifi R, El Kihal L, Hassar M, Akil A, Pineau P, Benjelloun S (2009) Single nucleotide polymorphism in DNMT3B promoter and its association with hepatocellular carcinoma in a Moroccan population. Infect Genet Evol 9: 877-881.
-
(2009)
Infect Genet Evol
, vol.9
, pp. 877-881
-
-
Ezzikouri, S.1
El Feydi, A.E.2
Benazzouz, M.3
Afifi, R.4
El Kihal, L.5
Hassar, M.6
Akil, A.7
Pineau, P.8
Benjelloun, S.9
-
57
-
-
79951499200
-
Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia
-
Fabris S, Bollati V, Agnelli L, Morabito F, Motta V, Cutrona G, Matis S, Recchia AG, Gigliotti V, Gentile M et al (2011) Biological and clinical relevance of quantitative global methylation of repetitive DNA sequences in chronic lymphocytic leukemia. Epigenetics 6: 188-194.
-
(2011)
Epigenetics
, vol.6
, pp. 188-194
-
-
Fabris, S.1
Bollati, V.2
Agnelli, L.3
Morabito, F.4
Motta, V.5
Cutrona, G.6
Matis, S.7
Recchia, A.G.8
Gigliotti, V.9
Gentile, M.10
-
58
-
-
0043136702
-
Lsh-deficient murine embryonalfibroblasts show reduced proliferation with signs of abnormal mitosis
-
Fan T, Yan Q, Huang J, Austin S, Cho E, Ferris D, Muegge K (2003) Lsh-deficient murine embryonalfibroblasts show reduced proliferation with signs of abnormal mitosis. Cancer Res 63: 4677-4683.
-
(2003)
Cancer Res
, vol.63
, pp. 4677-4683
-
-
Fan, T.1
Yan, Q.2
Huang, J.3
Austin, S.4
Cho, E.5
Ferris, D.6
Muegge, K.7
-
60
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B (2004) The history of cancer epigenetics. Nat Rev Cancer 4: 143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
61
-
-
0020699979
-
Hypomethylation distinguishes genes of some human cancers from their normal counterparts
-
Feinberg AP, Vogelstein B (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89-92.
-
(1983)
Nature
, vol.301
, pp. 89-92
-
-
Feinberg, A.P.1
Vogelstein, B.2
-
62
-
-
0023848637
-
Reduced genomic 5-methylcytosine genomic content in human colonic neoplasia
-
Feinberg AP, Ghrke CW, Kuo KC, Ehrlich M (1988) Reduced genomic 5-methylcytosine genomic content in human colonic neoplasia. Cancer Res 48: 1159-1161.
-
(1988)
Cancer Res
, vol.48
, pp. 1159-1161
-
-
Feinberg, A.P.1
Ghrke, C.W.2
Kuo, K.C.3
Ehrlich, M.4
-
64
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa ME, Abdel-Wahab O, Lu C, Ward PS, Patel J, Shih A, Li Y, Bhagwat N, Vasanthakumar A, Fernandez HF et al (2010) Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18: 553-567.
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
Ward, P.S.4
Patel, J.5
Shih, A.6
Li, Y.7
Bhagwat, N.8
Vasanthakumar, A.9
Fernandez, H.F.10
-
65
-
-
33646369393
-
Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band
-
Frigola J, Song J, Stirzaker C, Hinshelwood RA, Peinado MA, Clark SJ (2006) Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band. Nat Genet 38: 540-549.
-
(2006)
Nat Genet
, vol.38
, pp. 540-549
-
-
Frigola, J.1
Song, J.2
Stirzaker, C.3
Hinshelwood, R.A.4
Peinado, M.A.5
Clark, S.J.6
-
66
-
-
39649122136
-
Cancer epigenetics: Modifications, screening, and therapy
-
Gal-Yam EN, Saito Y, Egger G, Jones PA (2008) Cancer epigenetics: modifications, screening, and therapy. Annu Rev Med 59: 267-280.
-
(2008)
Annu Rev Med
, vol.59
, pp. 267-280
-
-
Gal-Yam, E.N.1
Saito, Y.2
Egger, G.3
Jones, P.A.4
-
67
-
-
0021101229
-
The 5-methylcytosine content of DNA from human tumors
-
Gama-Sosa MA, Slagel VA, Trewyn RW, Oxenhandler R, Kuo KC, Gehrke CW, Ehrlich M (1983) The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res 11: 6883-6894.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 6883-6894
-
-
Gama-Sosa, M.A.1
Slagel, V.A.2
Trewyn, R.W.3
Oxenhandler, R.4
Kuo, K.C.5
Gehrke, C.W.6
Ehrlich, M.7
-
68
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, Havelange V, Volinia S, Blum W, Rush LJ, Perrotti D, Andreeff M, Bloomfield CD, Byrd JC, Chan K, Wu LC, Croce CM, Marcucci G (2009) MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 113: 6411-6418.
-
(2009)
Blood
, vol.113
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
Liu, Z.4
Heaphy, C.E.5
Callegari, E.6
Schwind, S.7
Pang, J.8
Yu, J.9
Muthusamy, N.10
Havelange, V.11
Volinia, S.12
Blum, W.13
Rush, L.J.14
Perrotti, D.15
Andreeff, M.16
Bloomfield, C.D.17
Byrd, J.C.18
Chan, K.19
Wu, L.C.20
Croce, C.M.21
Marcucci, G.22
more..
-
69
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R (2003) Induction of tumors in mice by genomic hypomethylation. Science 300: 489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
Gray, J.W.6
Leonhardt, H.7
Jaenisch, R.8
-
70
-
-
0034069652
-
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
-
Gibbons RJ, McDowell TL, Raman S, O'Rourke DM, Garrick D, Ayyub H, Higgs DR (2000) Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat Genet 24: 368-371.
-
(2000)
Nat Genet
, vol.24
, pp. 368-371
-
-
Gibbons, R.J.1
McDowell, T.L.2
Raman, S.3
O'Rourke, D.M.4
Garrick, D.5
Ayyub, H.6
Higgs, D.R.7
-
71
-
-
0141995080
-
Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
-
Girault I, Tozlu S, Lidereau R, Bieche I (2003) Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res 9: 4415-4422.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4415-4422
-
-
Girault, I.1
Tozlu, S.2
Lidereau, R.3
Bieche, I.4
-
72
-
-
0021950948
-
Hypomethylation of DNA from benign and malignant human colon neoplasm's
-
Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP (1985) Hypomethylation of DNA from benign and malignant human colon neoplasm's. Science 228: 187-190.
-
(1985)
Science
, vol.228
, pp. 187-190
-
-
Goelz, S.E.1
Vogelstein, B.2
Hamilton, S.R.3
Feinberg, A.P.4
-
73
-
-
38449115628
-
DNA methylation profile at the DNMT3L promoter: A potential biomarker for cervical cancer
-
Gokul G, Gautami B, Malathi S, Sowjanya AP, Poli UR, Jain M, Ramakrishna G, Khosla S (2007) DNA methylation profile at the DNMT3L promoter: a potential biomarker for cervical cancer. Epigenetics 2: 80-85.
-
(2007)
Epigenetics
, vol.2
, pp. 80-85
-
-
Gokul, G.1
Gautami, B.2
Malathi, S.3
Sowjanya, A.P.4
Poli, U.R.5
Jain, M.6
Ramakrishna, G.7
Khosla, S.8
-
74
-
-
69949107733
-
Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis
-
Gokul G, Ramakrishna G, Khosla S (2009) Reprogramming of HeLa cells upon DNMT3L overexpression mimics carcinogenesis. Epigenetics 4: 322-329.
-
(2009)
Epigenetics
, vol.4
, pp. 322-329
-
-
Gokul, G.1
Ramakrishna, G.2
Khosla, S.3
-
75
-
-
74249095339
-
ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma
-
Gotze S, Feldhaus V, Traska T, Wolter M, Reifenberger G, Tannapfel A, Kuhnen C, Martin D, Muller O, Sievers S (2009) ECRG4 is a candidate tumor suppressor gene frequently hypermethylated in colorectal carcinoma and glioma. BMC Cancer 9: 447.
-
(2009)
BMC Cancer
, vol.9
-
-
Gotze, S.1
Feldhaus, V.2
Traska, T.3
Wolter, M.4
Reifenberger, G.5
Tannapfel, A.6
Kuhnen, C.7
Martin, D.8
Muller, O.9
Sievers, S.10
-
76
-
-
17144369504
-
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
-
Gowher H, Liebert K, Hermann A, Xu G, Jeltsch A (2005) Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L. J Biol Chem 280: 13341-13348.
-
(2005)
J Biol Chem
, vol.280
, pp. 13341-13348
-
-
Gowher, H.1
Liebert, K.2
Hermann, A.3
Xu, G.4
Jeltsch, A.5
-
77
-
-
40049102090
-
Inheritance of an epigenetic mark: The CpG DNA methyltransferase1 is required for de novo establishment of a complex pattern of non-CpG methylation
-
Grandjean V, Yaman R, Cuzin F, Rassoulzadegan M (2007) Inheritance of an epigenetic mark: the CpG DNA methyltransferase1 is required for de novo establishment of a complex pattern of non-CpG methylation. PLoS One 2: e1136.
-
(2007)
PLoS One
, vol.2
-
-
Grandjean, V.1
Yaman, R.2
Cuzin, F.3
Rassoulzadegan, M.4
-
78
-
-
0024365892
-
Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma
-
Greger V, Passarge E, Hopping W, Messmer E, Horsthemke B (1989) Epigenetic changes may contribute to the formation and spontaneous regression of retinoblastoma. Hum Genet 83: 155-158.
-
(1989)
Hum Genet
, vol.83
, pp. 155-158
-
-
Greger, V.1
Passarge, E.2
Hopping, W.3
Messmer, E.4
Horsthemke, B.5
-
79
-
-
77956192737
-
Genomic imprinting and human disease
-
Hirasawa R, Feil R (2010) Genomic imprinting and human disease. Essays Biochem 48: 187-200.
-
(2010)
Essays Biochem
, vol.48
, pp. 187-200
-
-
Hirasawa, R.1
Feil, R.2
-
80
-
-
77950347697
-
DNMT3B promoter Polymorphism and risk of gastric cancer
-
Hu J, Fan H, Liu D, Zhang S, Zhang F, Xu H (2010) DNMT3B promoter Polymorphism and risk of gastric cancer. Dig Dis Sci 55: 1011-1016.
-
(2010)
Dig Dis Sci
, vol.55
, pp. 1011-1016
-
-
Hu, J.1
Fan, H.2
Liu, D.3
Zhang, S.4
Zhang, F.5
Xu, H.6
-
81
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal K, Jin SG, Pfeifer GP, Szabó PE (2011) Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc Natl Acad Sci USA 108: 3642-3647.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabó, P.E.4
-
82
-
-
0042025123
-
Methylation and prognosis: Of molecular clocks and hypermethylator phenotypes
-
Issa JP (2003) Methylation and prognosis: of molecular clocks and hypermethylator phenotypes. Clin Cancer Res 9: 2879-2881.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2879-2881
-
-
Issa, J.P.1
-
83
-
-
10344260184
-
CpG island methylator phenotype in cancer
-
Issa JP (2004) CpG island methylator phenotype in cancer. Nat Rev Cancer 4: 988-993.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 988-993
-
-
Issa, J.P.1
-
84
-
-
34250213859
-
DNA methylation as a therapeutic target in cancer
-
Issa JP (2007) DNA methylation as a therapeutic target in cancer. Clin Cancer Res 13: 1634-1637.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1634-1637
-
-
Issa, J.P.1
-
85
-
-
0027198976
-
Increased cytosine DNA-methyltransferase activity during colon cancer progression
-
Issa JP, Vertino PM, Wu J, Sazawal S, Celano P, Nelkin BD, Hamilton SR, Baylin SB (1993) Increased cytosine DNA-methyltransferase activity during colon cancer progression. J Natl Cancer Inst 85: 1235-1240.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1235-1240
-
-
Issa, J.P.1
Vertino, P.M.2
Wu, J.3
Sazawal, S.4
Celano, P.5
Nelkin, B.D.6
Hamilton, S.R.7
Baylin, S.B.8
-
86
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB (1994) Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 7: 536-540.
-
(1994)
Nat Genet
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
Ottaviano, Y.L.2
Celano, P.3
Hamilton, S.R.4
Davidson, N.E.5
Baylin, S.B.6
-
87
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
-
Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, Zhang Y (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466: 1129-1133.
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
D'Alessio, A.C.2
Taranova, O.V.3
Hong, K.4
Sowers, L.C.5
Zhang, Y.6
-
88
-
-
34447104563
-
Mutator pathways unleashed by epigenetic silencing in human cancer
-
Jacinto FV, Esteller M (2007) Mutator pathways unleashed by epigenetic silencing in human cancer. Mutagenesis 22: 247-253.
-
(2007)
Mutagenesis
, vol.22
, pp. 247-253
-
-
Jacinto, F.V.1
Esteller, M.2
-
89
-
-
31544467813
-
De novo CpG island methylation in human cancer cells
-
Jair KW, Bachman KE, Suzuki H, Ting AH, Rhee I, Yen RW, Baylin SB, Schuebel KE (2006) De novo CpG island methylation in human cancer cells. Cancer Res 66: 682-692.
-
(2006)
Cancer Res
, vol.66
, pp. 682-692
-
-
Jair, K.W.1
Bachman, K.E.2
Suzuki, H.3
Ting, A.H.4
Rhee, I.5
Yen, R.W.6
Baylin, S.B.7
Schuebel, K.E.8
-
90
-
-
33749172559
-
Stem cell ageing modified by the cyclin-dependent kinase inhibitor p16(INK4a)
-
Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT (2006) Stem cell ageing modified by the cyclin-dependent kinase inhibitor p16(INK4a). Nature 443: 421-426.
-
(2006)
Nature
, vol.443
, pp. 421-426
-
-
Janzen, V.1
Forkert, R.2
Fleming, H.E.3
Saito, Y.4
Waring, M.T.5
Dombkowski, D.M.6
Cheng, T.7
DePinho, R.A.8
Sharpless, N.E.9
Scadden, D.T.10
-
91
-
-
33846581497
-
Loss of imprinting and cancer
-
Jelinic P, Shaw P (2007) Loss of imprinting and cancer. J Pathol 211: 261-268.
-
(2007)
J Pathol
, vol.211
, pp. 261-268
-
-
Jelinic, P.1
Shaw, P.2
-
92
-
-
0033541448
-
Genomic imprinting and cancer
-
Jirtle RL (1999) Genomic imprinting and cancer. Exp Cell Res 248: 18-24.
-
(1999)
Exp Cell Res
, vol.248
, pp. 18-24
-
-
Jirtle, R.L.1
-
93
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3: 415-428.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
94
-
-
0030909592
-
Altered DNA methylation and genome instability: A new pathway to cancer?
-
Jones PA, Gonzalgo ML (1997) Altered DNA methylation and genome instability: a new pathway to cancer? Proc Natl Acad Sci USA 94: 2103-2105.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2103-2105
-
-
Jones, P.A.1
Gonzalgo, M.L.2
-
95
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones PL, Veenstra GJ, Wade PA, Vermaak D, Kass SU, Landsberger N, Strouboulis J, Wolffe AP (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat Genet 19: 187-191.
-
(1998)
Nat Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
96
-
-
77949696376
-
Frequent promoter hypermethylation of the APC and RASSF1A tumor suppressors in parathyroid tumors
-
Juhlin CC, Kiss NB, Villablanca A, Haglund F, Nordenstrom J, Hoog A, Larsson C (2010) Frequent promoter hypermethylation of the APC and RASSF1A tumor suppressors in parathyroid tumors. PLoS One 5: e9472.
-
(2010)
PLoS One
, vol.5
-
-
Juhlin, C.C.1
Kiss, N.B.2
Villablanca, A.3
Haglund, F.4
Nordenstrom, J.5
Hoog, A.6
Larsson, C.7
-
97
-
-
0028151343
-
Toxicity of 5-aza-2ʹ-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R, Li E, Jaenisch R (1994) Toxicity of 5-aza-2ʹ-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 91: 11797-11801.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
Li, E.2
Jaenisch, R.3
-
98
-
-
49749094793
-
Alterations of DNA methylation and clinicopathological diversity of human cancers
-
Kanai Y (2008) Alterations of DNA methylation and clinicopathological diversity of human cancers. Pathol Int 58: 544-558.
-
(2008)
Pathol Int
, vol.58
, pp. 544-558
-
-
Kanai, Y.1
-
99
-
-
3042584653
-
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting
-
Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H (2004) Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429: 900-903.
-
(2004)
Nature
, vol.429
, pp. 900-903
-
-
Kaneda, M.1
Okano, M.2
Hata, K.3
Sado, T.4
Tsujimoto, N.5
Li, E.6
Sasaki, H.7
-
100
-
-
33748740832
-
Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L
-
Kareta MS, Botello ZM, Ennis JJ, Chou C, Chedin F (2006) Reconstitution and mechanism of the stimulation of de novo methylation by human DNMT3L. J Biol Chem 281: 25893-25902.
-
(2006)
J Biol Chem
, vol.281
, pp. 25893-25902
-
-
Kareta, M.S.1
Botello, Z.M.2
Ennis, J.J.3
Chou, C.4
Chedin, F.5
-
101
-
-
0022545498
-
DNA methylation affects the formation of active chromatin
-
Keshet I, Lieman-Hurwitz J, Cedar H (1986) DNA methylation affects the formation of active chromatin. Cell 44: 535-543.
-
(1986)
Cell
, vol.44
, pp. 535-543
-
-
Keshet, I.1
Lieman-Hurwitz, J.2
Cedar, H.3
-
102
-
-
0036683055
-
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
-
Kim GD, Ni J, Kelesoglu N, Roberts RJ, Pradhan S (2002) Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J 21: 4183-4195.
-
(2002)
EMBO J
, vol.21
, pp. 4183-4195
-
-
Kim, G.D.1
Ni, J.2
Kelesoglu, N.3
Roberts, R.J.4
Pradhan, S.5
-
103
-
-
61349186329
-
Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas
-
Kim MJ, White-Cross JA, Shen L, Issa JP, Rashid A (2009) Hypomethylation of long interspersed nuclear element-1 in hepatocellular carcinomas. Mod Pathol 22: 442-449.
-
(2009)
Mod Pathol
, vol.22
, pp. 442-449
-
-
Kim, M.J.1
White-Cross, J.A.2
Shen, L.3
Issa, J.P.4
Rashid, A.5
-
104
-
-
0032487675
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells
-
Kiyono T, Foster SA, Koop JI, McDougall JK, Galloway DA, Klingelhutz AJ (1998) Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. Nature 396: 84-88.
-
(1998)
Nature
, vol.396
, pp. 84-88
-
-
Kiyono, T.1
Foster, S.A.2
Koop, J.I.3
McDougall, J.K.4
Galloway, D.A.5
Klingelhutz, A.J.6
-
105
-
-
69249236962
-
The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia
-
Klemm L, Duy C, Iacobucci I, Kuchen S, von Levetzow G, Feldhahn N, Henke N, Li Z, Hoffmann TK, Kim YM, Hofmann WK, Jumaa H, Groffen J, Heisterkamp N, Martinelli G, Lieber MR, Casellas R, Müschen M (2009) The B cell mutator AID promotes B lymphoid blast crisis and drug resistance in chronic myeloid leukemia. Cancer Cell 16: 232-245.
-
(2009)
Cancer Cell
, vol.16
, pp. 232-245
-
-
Klemm, L.1
Duy, C.2
Iacobucci, I.3
Kuchen, S.4
von Levetzow, G.5
Feldhahn, N.6
Henke, N.7
Li, Z.8
Hoffmann, T.K.9
Kim, Y.M.10
Hofmann, W.K.11
Jumaa, H.12
Groffen, J.13
Heisterkamp, N.14
Martinelli, G.15
Lieber, M.R.16
Casellas, R.17
Müschen, M.18
-
106
-
-
32344450824
-
Genomic DNA methylation: The mark and its mediators
-
Klose RJ, Bird AP (2006) Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31: 89-97.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
107
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68: 820-823.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson, A.G.1
-
108
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko M, Huang Y, Jankowska AM, Pape UJ, Tahiliani M, Bandukwala HS, An J, Lamperti ED, Koh KP, Ganetzky R, Liu XS et al (2010) Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468: 839-843.
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
Huang, Y.2
Jankowska, A.M.3
Pape, U.J.4
Tahiliani, M.5
Bandukwala, H.S.6
An, J.7
Lamperti, E.D.8
Koh, K.P.9
Ganetzky, R.10
Liu, X.S.11
-
109
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, Heintz N (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324: 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
110
-
-
33749187810
-
P16(INK4a) induces an age-independent decline in islet regenerative potential
-
Krishnamurthy J, Ramsey MR, Ligon KL, Torrice C, Koh A, Bonner-Weir S, Sharpless NE (2006) P16(INK4a) induces an age-independent decline in islet regenerative potential. Nature 443: 453-457.
-
(2006)
Nature
, vol.443
, pp. 453-457
-
-
Krishnamurthy, J.1
Ramsey, M.R.2
Ligon, K.L.3
Torrice, C.4
Koh, A.5
Bonner-Weir, S.6
Sharpless, N.E.7
-
111
-
-
35548934558
-
MLL translocations, histone modifications and leukaemia stem-cell development
-
Krivtsov AV, Armstrong SA (2007) MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 7: 823-833.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
112
-
-
79959765942
-
Chromatin modifying agents-the cutting edge of anticancer therapy
-
Kwa FA, Balcerczyk A, Licciardi P, El-Osta A, Karagiannis TC (2011) Chromatin modifying agents-the cutting edge of anticancer therapy. Drug Discov Today 16: 543-547.
-
(2011)
Drug Discov Today
, vol.16
, pp. 543-547
-
-
Kwa, F.A.1
Balcerczyk, A.2
Licciardi, P.3
El-Osta, A.4
Karagiannis, T.C.5
-
113
-
-
0037379406
-
Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
-
Lacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, Rosty C, Walter K, Sato N, Parker A, Ashfaq R et al (2003) Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol 162: 1151-1162.
-
(2003)
Am J Pathol
, vol.162
, pp. 1151-1162
-
-
Lacobuzio-Donahue, C.A.1
Maitra, A.2
Olsen, M.3
Lowe, A.W.4
van Heek, N.T.5
Rosty, C.6
Walter, K.7
Sato, N.8
Parker, A.9
Ashfaq, R.10
-
114
-
-
0038576158
-
The power and the promise of DNA methylation markers
-
Laird PW (2003) The power and the promise of DNA methylation markers. Nat Rev Cancer 3: 253-266.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 253-266
-
-
Laird, P.W.1
-
115
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird PW, Jackson-Grusby L, Fazeli A, Dickinson SL, Jung WE, Li E, Weinberg RA, Jaenisch R (1995) Suppression of intestinal neoplasia by DNA hypomethylation. Cell 81: 197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
Jackson-Grusby, L.2
Fazeli, A.3
Dickinson, S.L.4
Jung, W.E.5
Li, E.6
Weinberg, R.A.7
Jaenisch, R.8
-
116
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W et al (2001) Initial sequencing and analysis of the human genome. Nature 409: 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
FitzHugh, W.10
-
117
-
-
78651316195
-
TET2 mutations in childhood leukemia
-
Langemeijer SM, Jansen JH, Hooijer J, van Hoogen P, Stevens-Linders E, Massop M, Waanders E, van Reijmersdal SV, Stevens-Kroef MJ, Zwaan CM et al (2011) TET2 mutations in childhood leukemia. Leukemia 25: 189-192.
-
(2011)
Leukemia
, vol.25
, pp. 189-192
-
-
Langemeijer, S.M.1
Jansen, J.H.2
Hooijer, J.3
van Hoogen, P.4
Stevens-Linders, E.5
Massop, M.6
Waanders, E.7
van Reijmersdal, S.V.8
Stevens-Kroef, M.J.9
Zwaan, C.M.10
-
118
-
-
44049115577
-
Choice of enzymes for mapping based on CpG islands in the human genome
-
Larsen F, Gundersen G, Prydz H (1992) Choice of enzymes for mapping based on CpG islands in the human genome. Genet Anal Tech Appl 9: 80-85.
-
(1992)
Genet Anal Tech Appl
, vol.9
, pp. 80-85
-
-
Larsen, F.1
Gundersen, G.2
Prydz, H.3
-
119
-
-
0029803192
-
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
-
Lei H, Oh SP, Okano M, Jüttermann R, Goss KA, Jaenisch R, Li E (1996) De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122: 3195-3205.
-
(1996)
Development
, vol.122
, pp. 3195-3205
-
-
Lei, H.1
Oh, S.P.2
Okano, M.3
Jüttermann, R.4
Goss, K.A.5
Jaenisch, R.6
Li, E.7
-
120
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69: 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
121
-
-
0037486949
-
DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma
-
Li S, Chiang TC, Richard-Davis G, Barrett JC, Mclachlan JA (2003) DNA hypomethylation and imbalanced expression of DNA methyltransferases (DNMT1, 3A, and 3B) in human uterine leiomyoma. Gynecol Oncol 90: 123-130.
-
(2003)
Gynecol Oncol
, vol.90
, pp. 123-130
-
-
Li, S.1
Chiang, T.C.2
Richard-Davis, G.3
Barrett, J.C.4
Mclachlan, J.A.5
-
122
-
-
0037350661
-
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10; 11) (q22; q23)
-
Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing JR (2003) TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10; 11) (q22; q23). Leukemia 17: 637-641.
-
(2003)
Leukemia
, vol.17
, pp. 637-641
-
-
Lorsbach, R.B.1
Moore, J.2
Mathew, S.3
Raimondi, S.C.4
Mukatira, S.T.5
Downing, J.R.6
-
123
-
-
0033822364
-
Large-scale human promoter mapping using CpG islands
-
Loshikhes IP, Zhang MQ (2000) Large-scale human promoter mapping using CpG islands. Nat Genet 26: 61-63.
-
(2000)
Nat Genet
, vol.26
, pp. 61-63
-
-
Loshikhes, I.P.1
Zhang, M.Q.2
-
124
-
-
33646160623
-
Inflammation, a key event in cancer development
-
Lu H, Ouyang W, Huang C (2006) Inflammation, a key event in cancer development. Mol Cancer Res 4: 221-233.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 221-233
-
-
Lu, H.1
Ouyang, W.2
Huang, C.3
-
125
-
-
0035942170
-
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia
-
Magdinier F, Wolffe AP (2001) Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. Proc Natl Acad Sci USA 98: 4990-4995.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4990-4995
-
-
Magdinier, F.1
Wolffe, A.P.2
-
126
-
-
77955402779
-
Hypomethylation of the DNMT3L promoter in Ocular Surface Squamous Neoplasia (OSSN)
-
Manderwad GP, Gokul G, Kannabiran C, Honavar SG, Khosla S, Vemuganti G (2010) Hypomethylation of the DNMT3L promoter in Ocular Surface Squamous Neoplasia (OSSN). Arch Pathol Lab Med 134: 1193-1196.
-
(2010)
Arch Pathol Lab Med
, vol.134
, pp. 1193-1196
-
-
Manderwad, G.P.1
Gokul, G.2
Kannabiran, C.3
Honavar, S.G.4
Khosla, S.5
Vemuganti, G.6
-
127
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M et al (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
-
128
-
-
54249139623
-
MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells
-
Martin V, Jorgensen HF, Chaubert AS, Berger J, Barr H, Shaw P, Bird A, Chaubert P (2008) MBD2-mediated transcriptional repression of the p14ARF tumor suppressor gene in human colon cancer cells. Pathobiology 75: 281-287.
-
(2008)
Pathobiology
, vol.75
, pp. 281-287
-
-
Martin, V.1
Jorgensen, H.F.2
Chaubert, A.S.3
Berger, J.4
Barr, H.5
Shaw, P.6
Bird, A.7
Chaubert, P.8
-
129
-
-
77955660238
-
Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis
-
Marusawa H, Chiba T (2010) Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis. Curr Opin Immunol 22: 442-447.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 442-447
-
-
Marusawa, H.1
Chiba, T.2
-
130
-
-
79958714414
-
2ʹ-deoxy-5, 6-dihydro-5-azacytidine-a less toxic alternative of 2ʹ-deoxy-5-azacytidine: A comparative study of hypomethylating potential
-
Matousova M, Votruba I, Otmar M, Tloustova E, Gunterova J, Mertlikova-kaiserova H (2011) 2ʹ-deoxy-5, 6-dihydro-5-azacytidine-a less toxic alternative of 2ʹ-deoxy-5-azacytidine: a comparative study of hypomethylating potential. Epigenetics 6: 769-776.
-
(2011)
Epigenetics
, vol.6
, pp. 769-776
-
-
Matousova, M.1
Votruba, I.2
Otmar, M.3
Tloustova, E.4
Gunterova, J.5
Mertlikova-kaiserova, H.6
-
131
-
-
34147180434
-
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
-
Matsumoto Y, Marusawa H, Kinoshita K, Endo Y, Kou T, Morisawa T, Azuma T, Okazaki IM, Honjo T, Chiba T (2007) Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium. Nat Med 13: 470-476.
-
(2007)
Nat Med
, vol.13
, pp. 470-476
-
-
Matsumoto, Y.1
Marusawa, H.2
Kinoshita, K.3
Endo, Y.4
Kou, T.5
Morisawa, T.6
Azuma, T.7
Okazaki, I.M.8
Honjo, T.9
Chiba, T.10
-
132
-
-
78649688865
-
Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer
-
Matsumoto Y, Marusawa H, Kinoshita K, Niwa Y, Sakai Y, Chiba T (2010) Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer. Gastroenterology 139: 1984-1994.
-
(2010)
Gastroenterology
, vol.139
, pp. 1984-1994
-
-
Matsumoto, Y.1
Marusawa, H.2
Kinoshita, K.3
Niwa, Y.4
Sakai, Y.5
Chiba, T.6
-
133
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W, Niveleau A, Walter J, Fundele R, Haaf T (2000) Demethylation of the zygotic paternal genome. Nature 403: 501-502.
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
135
-
-
77952385407
-
DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma
-
Minami K, Chano T, Kawakami T, Ushida H, Kushima R, Okabe H, Okada Y, Okamoto K (2010) DNMT3L is a novel marker and is essential for the growth of human embryonal carcinoma. Clin Cancer Res 16: 2751-2759.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2751-2759
-
-
Minami, K.1
Chano, T.2
Kawakami, T.3
Ushida, H.4
Kushima, R.5
Okabe, H.6
Okada, Y.7
Okamoto, K.8
-
137
-
-
79956117582
-
Global DNA methylation in precancerous and cancerous lesions of the uterine cervix
-
Missaoui N, Hmissa S, Dante R, Frappart L (2010) Global DNA methylation in precancerous and cancerous lesions of the uterine cervix. Asian Pac J Cancer Prev 11: 1741-1744.
-
(2010)
Asian Pac J Cancer Prev
, vol.11
, pp. 1741-1744
-
-
Missaoui, N.1
Hmissa, S.2
Dante, R.3
Frappart, L.4
-
138
-
-
33749171885
-
Increasing p16(INK4a) expression decreases forebrain progenitors and neurogenesis during ageing
-
Molofsky AV, Slutsky SG, Joseph NM, He S, Pardal R, Krishnamurthy J, Sharpless NE, Morrison SJ (2006) Increasing p16(INK4a) expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443: 448-452.
-
(2006)
Nature
, vol.443
, pp. 448-452
-
-
Molofsky, A.V.1
Slutsky, S.G.2
Joseph, N.M.3
He, S.4
Pardal, R.5
Krishnamurthy, J.6
Sharpless, N.E.7
Morrison, S.J.8
-
139
-
-
0035196111
-
Potential of 5-aza-2ʹ-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer
-
Momparler RL, Ayoub J (2001) Potential of 5-aza-2ʹ-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer. Lung Cancer 34(Suppl 4): S111-S1115.
-
(2001)
Lung Cancer
, vol.34
, pp. S111-S1115
-
-
Momparler, R.L.1
Ayoub, J.2
-
141
-
-
0022404250
-
Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2ʹ-deoxycytidine
-
Momparler RL, Bouchard J, Samson J (1985) Induction of differentiation and inhibition of DNA methylation in HL-60 myeloid leukemic cells by 5-AZA-2ʹ-deoxycytidine. Leuk Res 9: 1361-1366.
-
(1985)
Leuk Res
, vol.9
, pp. 1361-1366
-
-
Momparler, R.L.1
Bouchard, J.2
Samson, J.3
-
142
-
-
0022439016
-
5-Aza-2ʹ-deoxycytidine synergistic action with thymidine on leukemic cells and interaction of 5-AZA-dCMP with dCMP deaminase
-
Momparler RL, Rossi M, Bouchard J, Bartolucci S, Momparler LF, Raia CA, Nucci R, Vaccaro C, Sepe S (1986) 5-Aza-2ʹ-deoxycytidine synergistic action with thymidine on leukemic cells and interaction of 5-AZA-dCMP with dCMP deaminase. Adv Exp Med Biol 195 Pt B: 157-163.
-
(1986)
Adv Exp Med Biol
, vol.195
, pp. 157-163
-
-
Momparler, R.L.1
Rossi, M.2
Bouchard, J.3
Bartolucci, S.4
Momparler, L.F.5
Raia, C.A.6
Nucci, R.7
Vaccaro, C.8
Sepe, S.9
-
143
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK (2004) Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 279: 52353-52360.
-
(2004)
J Biol Chem
, vol.279
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
144
-
-
0346121833
-
MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status
-
Muller HM, Fiegl H, Goebel G, Hubalek MM, Widschwendter A, Muller-Holzner E, Marth C, Widschwendter M (2003) MeCP2 and MBD2 expression in human neoplastic and non-neoplastic breast tissue and its association with oestrogen receptor status. Br J Cancer 89: 1934-1939.
-
(2003)
Br J Cancer
, vol.89
, pp. 1934-1939
-
-
Muller, H.M.1
Fiegl, H.2
Goebel, G.3
Hubalek, M.M.4
Widschwendter, A.5
Muller-Holzner, E.6
Marth, C.7
Widschwendter, M.8
-
145
-
-
0024539196
-
Base methylation and local DNA helix stability. Effect on the kinetics of cruciform extrusion
-
Murchie AI, Lilley DM (1989) Base methylation and local DNA helix stability. Effect on the kinetics of cruciform extrusion. J Mol Biol 205: 593-602.
-
(1989)
J Mol Biol
, vol.205
, pp. 593-602
-
-
Murchie, A.I.1
Lilley, D.M.2
-
146
-
-
0032468051
-
Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines
-
Nakamura N, Takenaga K (1998) Hypomethylation of the metastasis-associated S100A4 gene correlates with gene activation in human colon adenocarcinoma cell lines. Clin Exp Metastasis 16: 471-479.
-
(1998)
Clin Exp Metastasis
, vol.16
, pp. 471-479
-
-
Nakamura, N.1
Takenaga, K.2
-
147
-
-
0032574977
-
Transcriptional repression by the methyl-CG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A (1998) Transcriptional repression by the methyl-CG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393: 386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
148
-
-
78649353107
-
The role of inflammation in the pathogenesis of prostate cancer
-
Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB (2004) The role of inflammation in the pathogenesis of prostate cancer. J Urol 172: S6-S11.
-
(2004)
J Urol
, vol.172
, pp. S6-S11
-
-
Nelson, W.G.1
De Marzo, A.M.2
DeWeese, T.L.3
Isaacs, W.B.4
-
149
-
-
0036830336
-
Senescence and epigenetic dysregulation in cancer
-
Neumeister P, Albanese C, Balent B, Greally J, Pestell RG (2002) Senescence and epigenetic dysregulation in cancer. Int J Biochem Cell Biol 34: 1475-1490.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1475-1490
-
-
Neumeister, P.1
Albanese, C.2
Balent, B.3
Greally, J.4
Pestell, R.G.5
-
150
-
-
0032871399
-
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
-
Ng HH, Zhang Y, Hendrich B, Johnson CA, Turner BM, Erdjument-Bromage H, Tempst P, Reinberg D, Bird A (1999) MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat Genet 23: 58-61.
-
(1999)
Nat Genet
, vol.23
, pp. 58-61
-
-
Ng, H.H.1
Zhang, Y.2
Hendrich, B.3
Johnson, C.A.4
Turner, B.M.5
Erdjument-Bromage, H.6
Tempst, P.7
Reinberg, D.8
Bird, A.9
-
151
-
-
0037112369
-
Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine
-
Nguyen CT, Weisenberger DJ, Velicescu M, Gonzales FA, Lin JC, Liang G, Jones PA (2002) Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine. Cancer Res 62: 6456-6461.
-
(2002)
Cancer Res
, vol.62
, pp. 6456-6461
-
-
Nguyen, C.T.1
Weisenberger, D.J.2
Velicescu, M.3
Gonzales, F.A.4
Lin, J.C.5
Liang, G.6
Jones, P.A.7
-
152
-
-
0033607147
-
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
-
Nuovo GJ, Plaia TW, Belinsky SA, Baylin SB, Herman JG (1999) In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc Natl Acad Sci USA 96: 12754-12759.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 12754-12759
-
-
Nuovo, G.J.1
Plaia, T.W.2
Belinsky, S.A.3
Baylin, S.B.4
Herman, J.G.5
-
153
-
-
33846100356
-
A human colon cancer cell capable of initiating tumor growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S, Dick JE (2007) A human colon cancer cell capable of initiating tumor growth in immunodeficient mice. Nature 445: 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
154
-
-
57349138824
-
A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer
-
Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Chan AT, Schernhammer ES, Giovannucci EL, Fuchs CS (2008) A cohort study of tumoral LINE-1 hypomethylation and prognosis in colon cancer. J Natl Cancer Inst 100: 1734-1738.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1734-1738
-
-
Ogino, S.1
Nosho, K.2
Kirkner, G.J.3
Kawasaki, T.4
Chan, A.T.5
Schernhammer, E.S.6
Giovannucci, E.L.7
Fuchs, C.S.8
-
155
-
-
34248193264
-
Stem cell chromatin patterns: An instructive mechanism for DNA hypermethylation?
-
Ohm JE, Baylin SB (2007) Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation? Cell Cycle 6: 1040-1043.
-
(2007)
Cell Cycle
, vol.6
, pp. 1040-1043
-
-
Ohm, J.E.1
Baylin, S.B.2
-
156
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99: 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
157
-
-
0037099537
-
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10; 11)(q22; q23)
-
Ono R, Taki T, Taketani T, Taniwaki M, Kobayashi H, Hayashi Y (2002) LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10; 11)(q22; q23). Cancer Res 62: 4075-4080.
-
(2002)
Cancer Res
, vol.62
, pp. 4075-4080
-
-
Ono, R.1
Taki, T.2
Taketani, T.3
Taniwaki, M.4
Kobayashi, H.5
Hayashi, Y.6
-
158
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi SK, Bestor TH (2008) The colorful history of active DNA demethylation. Cell 133: 1145-1148.
-
(2008)
Cell
, vol.133
, pp. 1145-1148
-
-
Ooi, S.K.1
Bestor, T.H.2
-
159
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi SK, Qui C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH (2007) DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448: 714-717.
-
(2007)
Nature
, vol.448
, pp. 714-717
-
-
Ooi, S.K.1
Qui, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
Erdjument-Bromage, H.7
Tempst, P.8
Lin, S.P.9
Allis, C.D.10
Cheng, X.11
Bestor, T.H.12
-
160
-
-
77957901287
-
Dynamic instability of genomic methylation patterns in pluripotent stem cells
-
Ooi SK, Wolf D, Hartung O, Agarwal S, Daley GQ, Goff SP, Bestor TH (2010) Dynamic instability of genomic methylation patterns in pluripotent stem cells. Epigenet Chromatin 3: 17.
-
(2010)
Epigenet Chromatin
, vol.3
-
-
Ooi, S.K.1
Wolf, D.2
Hartung, O.3
Agarwal, S.4
Daley, G.Q.5
Goff, S.P.6
Bestor, T.H.7
-
161
-
-
1042263110
-
Promoter methylation of cyclin D2 gene in gastric carcinoma
-
Oshimo Y, Nakayama H, Ito R, Kitadai Y, Yoshida K, Chayama K, Yasui W (2003) Promoter methylation of cyclin D2 gene in gastric carcinoma. Int J Oncol 6: 1663-1670.
-
(2003)
Int J Oncol
, vol.6
, pp. 1663-1670
-
-
Oshimo, Y.1
Nakayama, H.2
Ito, R.3
Kitadai, Y.4
Yoshida, K.5
Chayama, K.6
Yasui, W.7
-
162
-
-
78649953952
-
Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome
-
Pancione M, Sabatino L, Fucci A, Carafa V, Nebbioso A, Forte N, Febbraro A, Parente D, Ambrosino C, Normanno N, Altucci L, Colantuoni V (2010) Epigenetic silencing of peroxisome proliferator-activated receptor γ is a biomarker for colorectal cancer progression and adverse patients' outcome. PLoS One 5: e14229.
-
(2010)
PLoS One
, vol.5
-
-
Pancione, M.1
Sabatino, L.2
Fucci, A.3
Carafa, V.4
Nebbioso, A.5
Forte, N.6
Febbraro, A.7
Parente, D.8
Ambrosino, C.9
Normanno, N.10
Altucci, L.11
Colantuoni, V.12
-
163
-
-
0027243484
-
5-Aza-2ʹ-deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: Past, present and future trends
-
Pinto A, Zagonel V (1993) 5-Aza-2ʹ-deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: past, present and future trends. Leukemia 7(Suppl 1): 51-60.
-
(1993)
Leukemia
, vol.7
, pp. 51-60
-
-
Pinto, A.1
Zagonel, V.2
-
164
-
-
0021160287
-
5-Aza-2ʹ-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias
-
Pinto A, Attadia V, Fusco A, Ferrara F, Spada OA, Di Fiore PP (1984) 5-Aza-2ʹ-deoxycytidine induces terminal differentiation of leukemic blasts from patients with acute myeloid leukemias. Blood 64: 922-929.
-
(1984)
Blood
, vol.64
, pp. 922-929
-
-
Pinto, A.1
Attadia, V.2
Fusco, A.3
Ferrara, F.4
Spada, O.A.5
Di Fiore, P.P.6
-
165
-
-
0022910389
-
Oncogenes and human neoplasia
-
Pitot HC (1986) Oncogenes and human neoplasia. Clin Lab Med 6: 167-179.
-
(1986)
Clin Lab Med
, vol.6
, pp. 167-179
-
-
Pitot, H.C.1
-
166
-
-
0037306633
-
Race-and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States)
-
Piyathilake CJ, Henao O, Frost AR, Macaluso M, Bell WC, Johanning GL, Heimburger DC, Niveleau A, Grizzle WE (2003) Race-and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States). Cancer Causes Control 14: 37-42.
-
(2003)
Cancer Causes Control
, vol.14
, pp. 37-42
-
-
Piyathilake, C.J.1
Henao, O.2
Frost, A.R.3
Macaluso, M.4
Bell, W.C.5
Johanning, G.L.6
Heimburger, D.C.7
Niveleau, A.8
Grizzle, W.E.9
-
167
-
-
0035183199
-
Determinants of CpG islands: Expression in early embryo and isochore structure
-
Ponger L, Duret L, Mouchiroud D (2001) Determinants of CpG islands: expression in early embryo and isochore structure. Genome Res 11: 1854-1860.
-
(2001)
Genome Res
, vol.11
, pp. 1854-1860
-
-
Ponger, L.1
Duret, L.2
Mouchiroud, D.3
-
168
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp C, Dean W, Feng S, Cokus SJ, Andrews S, Pellegrini M, Jacobsen SE, Reik W (2010) Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 463: 1101-1105.
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
Dean, W.2
Feng, S.3
Cokus, S.J.4
Andrews, S.5
Pellegrini, M.6
Jacobsen, S.E.7
Reik, W.8
-
169
-
-
0035394961
-
The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor
-
Prokhortchouk A, Hendrich B, Jørgensen H, Ruzov A, Wilm M, Georgiev G, Bird A, Prokhortchouk E (2001) The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor. Genes Dev 15: 1613-1618.
-
(2001)
Genes Dev
, vol.15
, pp. 1613-1618
-
-
Prokhortchouk, A.1
Hendrich, B.2
Jørgensen, H.3
Ruzov, A.4
Wilm, M.5
Georgiev, G.6
Bird, A.7
Prokhortchouk, E.8
-
170
-
-
32344449372
-
Kaiso-deficient mice show resistance to intestinal cancer
-
Prokhortchouk A, Sansom O, Selfridge J, Caballero IM, Salozhin S, Aithozhina D, Cerchietti L, Meng FG, Augenlicht LH, Mariadason JM et al (2006) Kaiso-deficient mice show resistance to intestinal cancer. Mol Cell Biol 26: 199-208.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 199-208
-
-
Prokhortchouk, A.1
Sansom, O.2
Selfridge, J.3
Caballero, I.M.4
Salozhin, S.5
Aithozhina, D.6
Cerchietti, L.7
Meng, F.G.8
Augenlicht, L.H.9
Mariadason, J.M.10
-
171
-
-
0033081639
-
Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16
-
Qu GZ, Grundy PE, Narayan A, Ehrlich M (1999) Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16. Cancer Genet Cytogenet 109: 34-39.
-
(1999)
Cancer Genet Cytogenet
, vol.109
, pp. 34-39
-
-
Qu, G.Z.1
Grundy, P.E.2
Narayan, A.3
Ehrlich, M.4
-
172
-
-
78049515403
-
Overexpression of DNA methyltransferases 1, 3a, and 3b significantly correlates with retinoblastoma tumorigenesis
-
Qu Y, Mu G, Wu Y, Dai X, Zhou F, Xu X, Wang Y, Wei F (2010) Overexpression of DNA methyltransferases 1, 3a, and 3b significantly correlates with retinoblastoma tumorigenesis. Am J Clin Pathol 134: 826-834.
-
(2010)
Am J Clin Pathol
, vol.134
, pp. 826-834
-
-
Qu, Y.1
Mu, G.2
Wu, Y.3
Dai, X.4
Zhou, F.5
Xu, X.6
Wang, Y.7
Wei, F.8
-
173
-
-
79551513940
-
Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer
-
Radpour R, Barekati Z, Kohler C, Lv Q, Burki N, Diesch C, Bitzer J, Zheng H, Schmid S, Zhong XY (2011) Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer. PLoS One 6: e16080.
-
(2011)
PLoS One
, vol.6
-
-
Radpour, R.1
Barekati, Z.2
Kohler, C.3
Lv, Q.4
Burki, N.5
Diesch, C.6
Bitzer, J.7
Zheng, H.8
Schmid, S.9
Zhong, X.Y.10
-
174
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR (2008) DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 135: 1201-1212.
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
Karpf, A.R.4
Jones, D.A.5
Cairns, B.R.6
-
175
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye BH, Biniszkiewicz D, Lyko F, Clark V, Bird AP, Jaenisch R (2000) Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc Natl Acad Sci USA 97: 5237-5242.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
Biniszkiewicz, D.2
Lyko, F.3
Clark, V.4
Bird, A.P.5
Jaenisch, R.6
-
176
-
-
14644425319
-
Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia
-
Ren R (2005) Mechanisms of BCR-ABL in the pathogenesis of chronic myelogenous leukaemia. Nat Rev Cancer 5: 172-183.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 172-183
-
-
Ren, R.1
-
177
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)
-
Revy P, Muto T, Levy Y, Geissmann F, Plebani A, Sanal O, Catalan N, Forveille M, Dufourcq-Labelouse R, Gennery A et al (2000) Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2). Cell 102: 565-575.
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissmann, F.4
Plebani, A.5
Sanal, O.6
Catalan, N.7
Forveille, M.8
Dufourcq-Labelouse, R.9
Gennery, A.10
-
178
-
-
33747732171
-
Tumor suppressor P16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells
-
Reynolds PA, Sigaroudinia M, Zardo G, Wilson MB, Benton GM, Miller CJ, Hong C, Fridlyand J, Costello JF, Tlsty TD (2006) Tumor suppressor P16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells. J Biol Chem 281: 24790-24802.
-
(2006)
J Biol Chem
, vol.281
, pp. 24790-24802
-
-
Reynolds, P.A.1
Sigaroudinia, M.2
Zardo, G.3
Wilson, M.B.4
Benton, G.M.5
Miller, C.J.6
Hong, C.7
Fridlyand, J.8
Costello, J.F.9
Tlsty, T.D.10
-
179
-
-
0034720284
-
CpG methylation is maintained in human cancer cells lacking DNMT1
-
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG, Kinzler KW, Vogelstein B, Baylin SB, Schuebel KE (2000) CpG methylation is maintained in human cancer cells lacking DNMT1. Nature 404: 1003-1007.
-
(2000)
Nature
, vol.404
, pp. 1003-1007
-
-
Rhee, I.1
Jair, K.W.2
Yen, R.W.3
Lengauer, C.4
Herman, J.G.5
Kinzler, K.W.6
Vogelstein, B.7
Baylin, S.B.8
Schuebel, K.E.9
-
180
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B (2002) DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416: 552-556.
-
(2002)
Nature
, vol.416
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.W.4
Yen, R.W.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
181
-
-
0020986251
-
5-methylcytosine, gene regulation, and cancer
-
Riggs AD, Jones PA (1983) 5-methylcytosine, gene regulation, and cancer. Adv Cancer Res 40: 1-30.
-
(1983)
Adv Cancer Res
, vol.40
, pp. 1-30
-
-
Riggs, A.D.1
Jones, P.A.2
-
182
-
-
78650584064
-
CpG methylation of half-CRE sequences creates C/EBP alpha binding sites that activate some tissue-specific genes
-
Rishi V, Bhattacharya P, Chatterjee R, Rozenberg J, Zhao J, Glass K, Fitzgerald P, Vinson C (2010) CpG methylation of half-CRE sequences creates C/EBP alpha binding sites that activate some tissue-specific genes. Proc Natl Acad Sci USA 107: 20311-20316.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20311-20316
-
-
Rishi, V.1
Bhattacharya, P.2
Chatterjee, R.3
Rozenberg, J.4
Zhao, J.5
Glass, K.6
Fitzgerald, P.7
Vinson, C.8
-
183
-
-
0019857236
-
Phase I study on 5-aza-2ʹ-deoxycytidine in children with acute leukemia
-
Rivard GE, Momparler RL, Demers J, Benoit P, Raymond R, Lin K, Momparler LF (1981) Phase I study on 5-aza-2ʹ-deoxycytidine in children with acute leukemia. Leuk Res 5: 453-462.
-
(1981)
Leuk Res
, vol.5
, pp. 453-462
-
-
Rivard, G.E.1
Momparler, R.L.2
Demers, J.3
Benoit, P.4
Raymond, R.5
Lin, K.6
Momparler, L.F.7
-
184
-
-
70449641054
-
AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations
-
Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR et al (2009) AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Mol Cell 36: 631-641.
-
(2009)
Mol Cell
, vol.36
, pp. 631-641
-
-
Robbiani, D.F.1
Bunting, S.2
Feldhahn, N.3
Bothmer, A.4
Camps, J.5
Deroubaix, S.6
McBride, K.M.7
Klein, I.A.8
Stone, G.9
Eisenreich, T.R.10
-
185
-
-
0033153303
-
The human DNA methyltransferase (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA (1999) The human DNA methyltransferase (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res 27: 2291-2298.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgyi, E.2
Liang, G.3
Talmadge, C.4
Sumegi, J.5
Gonzales, F.A.6
Jones, P.A.7
-
186
-
-
0037162542
-
Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
-
Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hirohashi S (2002) Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis. Proc Natl Acad Sci USA 99: 10060-10065.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10060-10065
-
-
Saito, Y.1
Kanai, Y.2
Sakamoto, M.3
Saito, H.4
Ishii, H.5
Hirohashi, S.6
-
187
-
-
0037603586
-
Deficiency of Mbd2 suppresses intestinal tumorigenesis
-
Sansom OJ, Berger J, Bishop SM, Hendrich B, Bird A, Clarke AR (2003) Deficiency of Mbd2 suppresses intestinal tumorigenesis. Nat Genet 34: 145-147.
-
(2003)
Nat Genet
, vol.34
, pp. 145-147
-
-
Sansom, O.J.1
Berger, J.2
Bishop, S.M.3
Hendrich, B.4
Bird, A.5
Clarke, A.R.6
-
188
-
-
0000418476
-
Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
-
Santi DV, Norment A, Garrett CE (1984) Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc Natl Acad Sci USA 81: 6993-6997.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 6993-6997
-
-
Santi, D.V.1
Norment, A.2
Garrett, C.E.3
-
189
-
-
4344685735
-
Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly
-
Sarraf SA, Stancheva I (2004) Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Mol Cell 15: 595-605.
-
(2004)
Mol Cell
, vol.15
, pp. 595-605
-
-
Sarraf, S.A.1
Stancheva, I.2
-
190
-
-
0042674172
-
Frequent hyomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma
-
Sato N, Maitra A, Fukushima N, van Heek NT, Matsubayashi H, Iacobuzio-Donahue CA, Rosty C, Goggins M (2003) Frequent hyomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. Cancer Res 63: 4158-4166.
-
(2003)
Cancer Res
, vol.63
, pp. 4158-4166
-
-
Sato, N.1
Maitra, A.2
Fukushima, N.3
van Heek, N.T.4
Matsubayashi, H.5
Iacobuzio-Donahue, C.A.6
Rosty, C.7
Goggins, M.8
-
191
-
-
77949950879
-
Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancer
-
Schernhammer ES, Giovannucci E, Kawasaki T, Rosner B, Fuchs CS, Ogino S (2010) Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancer. Gut 59: 794-799.
-
(2010)
Gut
, vol.59
, pp. 794-799
-
-
Schernhammer, E.S.1
Giovannucci, E.2
Kawasaki, T.3
Rosner, B.4
Fuchs, C.S.5
Ogino, S.6
-
192
-
-
33646474281
-
AML patients with CEBPalpha mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: A comparative analysis on paired diagnosis and relapse samples
-
Shih LY, Liang DC, Huang CF, Wu JH, Lin TL, Wang PN, Dunn P, Kuo MC, Tang TC (2006) AML patients with CEBPalpha mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples. Leukemia 20: 604-609.
-
(2006)
Leukemia
, vol.20
, pp. 604-609
-
-
Shih, L.Y.1
Liang, D.C.2
Huang, C.F.3
Wu, J.H.4
Lin, T.L.5
Wang, P.N.6
Dunn, P.7
Kuo, M.C.8
Tang, T.C.9
-
193
-
-
78049484691
-
BRCA1 affects global DNA methylation through regulation of DNMT1
-
Shukla V, Coumoul X, Lahusen T, Wang RH, Xu X, Vassilopoulos A, Xiao C, Lee MH, Man YG, Ouchi M, Ouchi T, Deng CX (2010) BRCA1 affects global DNA methylation through regulation of DNMT1. Cell Res 20: 1201-1215.
-
(2010)
Cell Res
, vol.20
, pp. 1201-1215
-
-
Shukla, V.1
Coumoul, X.2
Lahusen, T.3
Wang, R.H.4
Xu, X.5
Vassilopoulos, A.6
Xiao, C.7
Lee, M.H.8
Man, Y.G.9
Ouchi, M.10
Ouchi, T.11
Deng, C.X.12
-
194
-
-
0018785482
-
Methylation of mouse liver DNA studied by means of the restriction enzymes MspI and HpaII
-
Singer J, Roberts-Ems J, Riggs AD (1979) Methylation of mouse liver DNA studied by means of the restriction enzymes MspI and HpaII. Science 203: 1019-1021.
-
(1979)
Science
, vol.203
, pp. 1019-1021
-
-
Singer, J.1
Roberts-Ems, J.2
Riggs, A.D.3
-
195
-
-
0009021282
-
The action of pancreatic deoxyribonuclease II isomeric dinucleotides
-
Sinsheimer RL (1955) The action of pancreatic deoxyribonuclease II isomeric dinucleotides. J Biol Chem 215: 579-583.
-
(1955)
J Biol Chem
, vol.215
, pp. 579-583
-
-
Sinsheimer, R.L.1
-
196
-
-
0013773866
-
5-Azacytidine, a new, highly effective cancerostatic
-
Sorm F, Piskala A, Cihak A, Vesely J (1964) 5-Azacytidine, a new, highly effective cancerostatic. Experientia 20: 202-203.
-
(1964)
Experientia
, vol.20
, pp. 202-203
-
-
Sorm, F.1
Piskala, A.2
Cihak, A.3
Vesely, J.4
-
197
-
-
0036230566
-
A genome wide screen for normally methylated human CpG islands that can identify normal imprinted genes
-
Strichman-Almashanu LZ, Lee RS, Onyango PO, Perlman E, Flam F, Frieman MB, Feinberg AP (2002) A genome wide screen for normally methylated human CpG islands that can identify normal imprinted genes. Genome Res 12: 543-554.
-
(2002)
Genome Res
, vol.12
, pp. 543-554
-
-
Strichman-Almashanu, L.Z.1
Lee, R.S.2
Onyango, P.O.3
Perlman, E.4
Flam, F.5
Frieman, M.B.6
Feinberg, A.P.7
-
198
-
-
3042641718
-
DNMT3L stimulates the DNA methylation activity of Dnmt3a and DNMT3B through a direct interaction
-
Suetake I, Shinozaki F, Miyagawa J, Takeshima H, Tajima S (2004) DNMT3L stimulates the DNA methylation activity of Dnmt3a and DNMT3B through a direct interaction. J Biol Chem 279: 27816-27823.
-
(2004)
J Biol Chem
, vol.279
, pp. 27816-27823
-
-
Suetake, I.1
Shinozaki, F.2
Miyagawa, J.3
Takeshima, H.4
Tajima, S.5
-
199
-
-
1242285594
-
Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue
-
Suter CM, Martin DI, Ward RL (2004) Hypomethylation of L1 retrotransposons in colorectal cancer and adjacent normal tissue. Int J Colorectal Dis 19: 95-101.
-
(2004)
Int J Colorectal Dis
, vol.19
, pp. 95-101
-
-
Suter, C.M.1
Martin, D.I.2
Ward, R.L.3
-
200
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, Chen WD, Pretlow TP, Yang B, Akiyama Y, Van Engeland M, Toyota M, Tokino T, Hinoda Y, Imai K, Herman JG, Baylin SB (2004) Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 36: 417-422.
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
Schuebel, K.E.4
Markowitz, S.D.5
Chen, W.D.6
Pretlow, T.P.7
Yang, B.8
Akiyama, Y.9
Van Engeland, M.10
Toyota, M.11
Tokino, T.12
Hinoda, Y.13
Imai, K.14
Herman, J.G.15
Baylin, S.B.16
-
201
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324: 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
Rao, A.11
-
202
-
-
0345603004
-
The CpG island searcher: A new WWW resource
-
Takai D, Jones PA (2003) The CpG island searcher: a new WWW resource. In Silico Biol 3: 235-240.
-
(2003)
In Silico Biol
, vol.3
, pp. 235-240
-
-
Takai, D.1
Jones, P.A.2
-
203
-
-
0021070915
-
Developmental activation of the H2K gene is correlated with an increase in DNA methylation
-
Tanaka K, Appella E, Jay G (1983) Developmental activation of the H2K gene is correlated with an increase in DNA methylation. Cell 35: 457-465.
-
(1983)
Cell
, vol.35
, pp. 457-465
-
-
Tanaka, K.1
Appella, E.2
Jay, G.3
-
204
-
-
2642574054
-
CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1
-
Ting AH, Jair KW, Suzuki H, Yen RW, Baylin SB, Schuebel KE (2004) CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1. Nat Genet 36: 582-584.
-
(2004)
Nat Genet
, vol.36
, pp. 582-584
-
-
Ting, A.H.1
Jair, K.W.2
Suzuki, H.3
Yen, R.W.4
Baylin, S.B.5
Schuebel, K.E.6
-
205
-
-
31544457309
-
Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation
-
Ting AH, Jair KW, Schuebel KE, Baylin SB (2006a) Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation. Cancer Res 66: 729-735.
-
(2006)
Cancer Res
, vol.66
, pp. 729-735
-
-
Ting, A.H.1
Jair, K.W.2
Schuebel, K.E.3
Baylin, S.B.4
-
206
-
-
33845417885
-
The cancer epigenome-components and functional correlates
-
Ting AH, McGarvey KM, Baylin SB (2006b) The cancer epigenome-components and functional correlates. Genes Dev 20: 3215-3231.
-
(2006)
Genes Dev
, vol.20
, pp. 3215-3231
-
-
Ting, A.H.1
McGarvey, K.M.2
Baylin, S.B.3
-
207
-
-
77956276643
-
Suppressive effect of global DNA hypomethylation on gastric carcinogenesis
-
Tomita H, Hirata A, Yamada Y, Hata K, Oyama T, Mori H, Yamashita S, Ushijima T, Hara A (2010) Suppressive effect of global DNA hypomethylation on gastric carcinogenesis. Carcinogenesis 31: 1627-1633.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1627-1633
-
-
Tomita, H.1
Hirata, A.2
Yamada, Y.3
Hata, K.4
Oyama, T.5
Mori, H.6
Yamashita, S.7
Ushijima, T.8
Hara, A.9
-
208
-
-
78549273319
-
When bacteria become mutagenic and carcinogenic: Lessons from H. pylori
-
Touati E (2010) When bacteria become mutagenic and carcinogenic: lessons from H. pylori. Mutat Res 703: 66-70.
-
(2010)
Mutat Res
, vol.703
, pp. 66-70
-
-
Touati, E.1
-
209
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP (1999) CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 96: 8681-8686.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
Herman, J.G.4
Baylin, S.B.5
Issa, J.P.6
-
210
-
-
0033933366
-
DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients
-
Tuck-Muller CM, Narayan A, Tsien F, Smeets DF, Sawyer J, Fiala ES, Sohn OS, Ehrlich M (2000) DNA hypomethylation and unusual chromosome instability in cell lines from ICF syndrome patients. Cytogenet Cell Genet 89: 121-128.
-
(2000)
Cytogenet Cell Genet
, vol.89
, pp. 121-128
-
-
Tuck-Muller, C.M.1
Narayan, A.2
Tsien, F.3
Smeets, D.F.4
Sawyer, J.5
Fiala, E.S.6
Sohn, O.S.7
Ehrlich, M.8
-
212
-
-
0035895505
-
The sequence of the human genome
-
Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA et al (2001) The sequence of the human genome. Science 291: 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
Smith, H.O.7
Yandell, M.8
Evans, C.A.9
Holt, R.A.10
-
213
-
-
0029973718
-
De novo methylation of CpG island sequences in humanfibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
-
Vertino PM, Yen RW, Gao J, Baylin SB (1996) De novo methylation of CpG island sequences in humanfibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol Cell Biol 16: 4555-4565.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4555-4565
-
-
Vertino, P.M.1
Yen, R.W.2
Gao, J.3
Baylin, S.B.4
-
214
-
-
77955490797
-
miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer
-
Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y (2010) miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer. Int J Cancer 127: 1106-1114.
-
(2010)
Int J Cancer
, vol.127
, pp. 1106-1114
-
-
Wada, R.1
Akiyama, Y.2
Hashimoto, Y.3
Fukamachi, H.4
Yuasa, Y.5
-
215
-
-
0032845039
-
Mi-2 complex couples DNA methylation to chromatin remodeling and histone deacetylation
-
Wade PA, Gegonne A, Jones PL, Ballestar E, Aubry F, Wolffe AP (1999) Mi-2 complex couples DNA methylation to chromatin remodeling and histone deacetylation. Nat Genet 23: 62-66.
-
(1999)
Nat Genet
, vol.23
, pp. 62-66
-
-
Wade, P.A.1
Gegonne, A.2
Jones, P.L.3
Ballestar, E.4
Aubry, F.5
Wolffe, A.P.6
-
216
-
-
78751508049
-
Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma
-
Walker BA, Wardell CP, Chiecchio L, Smith EM, Boyd KD, Neri A, Davies FE, Ross FM, Morgan GJ (2011) Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma. Blood 117: 553-562.
-
(2011)
Blood
, vol.117
, pp. 553-562
-
-
Walker, B.A.1
Wardell, C.P.2
Chiecchio, L.3
Smith, E.M.4
Boyd, K.D.5
Neri, A.6
Davies, F.E.7
Ross, F.M.8
Morgan, G.J.9
-
217
-
-
20144374921
-
Meiotic and epigenetic defects in DNMT3L-knockout mouse spermatogenesis
-
Webster KE, O'Bryan MK, Fletcher S, Crewther PE, Aapola U, Craig J, Harrison DK, Anug H, Phutikanit N, Lyle R, Meachem SJ, Antonarakis SE, de Kretser DM, Hedger MP, Peterson P, Carroll BJ, Scott HS (2005) Meiotic and epigenetic defects in DNMT3L-knockout mouse spermatogenesis. Proc Natl Acad Sci USA 102: 4068-4073.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4068-4073
-
-
Webster, K.E.1
O'Bryan, M.K.2
Fletcher, S.3
Crewther, P.E.4
Aapola, U.5
Craig, J.6
Harrison, D.K.7
Anug, H.8
Phutikanit, N.9
Lyle, R.10
Meachem, S.J.11
Antonarakis, S.E.12
de Kretser, D.M.13
Hedger, M.P.14
Peterson, P.15
Carroll, B.J.16
Scott, H.S.17
-
218
-
-
77649083131
-
Implications of LINE1 methylation for bladder cancer risk in women
-
Wilhelm CS, Kelsey KT, Butler R, Plaza S, Gagne L, Zens MS, Andrew AS, Morris S, Nelson HH, Schned AR, Karagas MR, Marsit CJ (2010) Implications of LINE1 methylation for bladder cancer risk in women. Clin Cancer Res 16: 1682-1689.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1682-1689
-
-
Wilhelm, C.S.1
Kelsey, K.T.2
Butler, R.3
Plaza, S.4
Gagne, L.5
Zens, M.S.6
Andrew, A.S.7
Morris, S.8
Nelson, H.H.9
Schned, A.R.10
Karagas, M.R.11
Marsit, C.J.12
-
219
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
Wu SC, Zhang Y (2010) Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol 11: 607-620.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
220
-
-
0027504621
-
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
-
Wu J, Issa JP, Herman J, Bassett DE Jr, Nelkin BD, Baylin SB (1993) Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells. Proc Natl Acad Sci USA 90: 8891-8895.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8891-8895
-
-
Wu, J.1
Issa, J.P.2
Herman, J.3
Bassett, D.E.4
Nelkin, B.D.5
Baylin, S.B.6
-
221
-
-
13844255666
-
Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers
-
Xiong Y, Dowdy SC, Xue A, Shujuan J, Eberhardt NL, Podratz KC, Jiang SW (2005) Opposite alterations of DNA methyltransferase gene expression in endometrioid and serous endometrial cancers. Gynecol Oncol 96: 601-609.
-
(2005)
Gynecol Oncol
, vol.96
, pp. 601-609
-
-
Xiong, Y.1
Dowdy, S.C.2
Xue, A.3
Shujuan, J.4
Eberhardt, N.L.5
Podratz, K.C.6
Jiang, S.W.7
-
222
-
-
0030840954
-
Cytosine methylation and the ecology of intragenomic parasites
-
Yoder JA, Walsh CP, Bestor TH (1997) Cytosine methylation and the ecology of intragenomic parasites. Trends Genet 13: 335-340.
-
(1997)
Trends Genet
, vol.13
, pp. 335-340
-
-
Yoder, J.A.1
Walsh, C.P.2
Bestor, T.H.3
-
223
-
-
0141638426
-
N-CoR mediates DNA methylationdependent repression through a methyl CpG binding protein Kaiso
-
Yoon HF, Chan DW, Reynolds AB, Qin J, Wong J (2003) N-CoR mediates DNA methylationdependent repression through a methyl CpG binding protein Kaiso. Mol Cell 12: 723-734.
-
(2003)
Mol Cell
, vol.12
, pp. 723-734
-
-
Yoon, H.F.1
Chan, D.W.2
Reynolds, A.B.3
Qin, J.4
Wong, J.5
-
224
-
-
78349292907
-
Alu and Sat α hypomethylation in Helicobacter pylori-infected gastric mucosae
-
Yoshida T, Yamashita S, Takamura-Enya T, Niwa T, Ando T, Enomoto S, Maekita T, Nakazawa K, Tatematsu M, Ichinose M, Ushijima T (2011) Alu and Sat α hypomethylation in Helicobacter pylori-infected gastric mucosae. Int J Cancer 128: 33-39.
-
(2011)
Int J Cancer
, vol.128
, pp. 33-39
-
-
Yoshida, T.1
Yamashita, S.2
Takamura-Enya, T.3
Niwa, T.4
Ando, T.5
Enomoto, S.6
Maekita, T.7
Nakazawa, K.8
Tatematsu, M.9
Ichinose, M.10
Ushijima, T.11
-
225
-
-
85063821394
-
Two-hit hypothesis of tumor suppressor gene and Revisions
-
Yu JC, Shen CY (2002) Two-hit hypothesis of tumor suppressor gene and Revisions. J Med Sci 22: 13-18.
-
(2002)
J Med Sci
, vol.22
, pp. 13-18
-
-
Yu, J.C.1
Shen, C.Y.2
-
226
-
-
77649163840
-
Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice
-
Yu S, Khor TO, Cheung KL, Li W, Wu TY, Huang Y, Foster BA, Kan YW, Kong AN (2010) Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice. PLoS One 5: e8579.
-
(2010)
PLoS One
, vol.5
-
-
Yu, S.1
Khor, T.O.2
Cheung, K.L.3
Li, W.4
Wu, T.Y.5
Huang, Y.6
Foster, B.A.7
Kan, Y.W.8
Kong, A.N.9
-
227
-
-
0025333258
-
Cytosine methylation enhances Z-DNA formation in vivo
-
Zacharias W, Jaworski A, Wells RD (1990) Cytosine methylation enhances Z-DNA formation in vivo. J Bacteriol 172: 3278-3283.
-
(1990)
J Bacteriol
, vol.172
, pp. 3278-3283
-
-
Zacharias, W.1
Jaworski, A.2
Wells, R.D.3
-
228
-
-
0033180082
-
Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
-
Zhang Y, Ng HH, Erdjument-Bromage H, Tempst P, Bird A, Reinberg D (1999) Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation. Genes Dev 13: 1924-1935.
-
(1999)
Genes Dev
, vol.13
, pp. 1924-1935
-
-
Zhang, Y.1
Ng, H.H.2
Erdjument-Bromage, H.3
Tempst, P.4
Bird, A.5
Reinberg, D.6
-
229
-
-
0031416750
-
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis
-
Zingg JM, Jones PA (1997) Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis 18: 869-882.
-
(1997)
Carcinogenesis
, vol.18
, pp. 869-882
-
-
Zingg, J.M.1
Jones, P.A.2
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