-
1
-
-
27644469013
-
Use of preclinical models to improve treatment of retinoblastoma
-
doi:10.1371/journal.pmed.0020332
-
Dyer MA, Rodriguez-Galindo C, Wilson MW. Use of preclinical models to improve treatment of retinoblastoma. PLoS Med. 2005;2:e332. doi:10.1371/journal. pmed.0020332.
-
(2005)
PLoS Med
, vol.2
-
-
Dyer, M.A.1
Rodriguez-Galindo, C.2
Wilson, M.W.3
-
2
-
-
0037299508
-
Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome
-
Lillington DM, Kingston JE, Coen PG, et al. Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome. Genes Chromosomes Cancer. 2003;36:121-128.
-
(2003)
Genes Chromosomes Cancer
, vol.36
, pp. 121-128
-
-
Lillington, D.M.1
Kingston, J.E.2
Coen, P.G.3
-
3
-
-
77649340617
-
Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas
-
published online December 11, doi:10.1016/j.humpath.2009.08.022
-
Mu G, Liu H, Zhou F, et al. Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas [published online December 11, 2009]. Hum Pathol. 2010;41:493-502. doi:10.1016/j.humpath.2009.08.022.
-
(2009)
Hum Pathol
, vol.41
, pp. 493-502
-
-
Mu, G.1
Liu, H.2
Zhou, F.3
-
4
-
-
34249004558
-
One hit, two hits, three hits, more? genomic changes in the development of retinoblastoma
-
Corson TW, Gallie BL. One hit, two hits, three hits, more? genomic changes in the development of retinoblastoma. Genes Chromosomes Cancer. 2007;46:617-634.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 617-634
-
-
Corson, T.W.1
Gallie, B.L.2
-
5
-
-
67650443984
-
Frontiers in the management of retinoblastoma
-
Lin P, O'Brien JM. Frontiers in the management of retinoblastoma. Am J Ophthalmol. 2009;148:192-198.
-
(2009)
Am J Ophthalmol
, vol.148
, pp. 192-198
-
-
Lin, P.1
O'Brien, J.M.2
-
6
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
DOI 10.1038/366362a0
-
Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature. 1993;366:362-365. (Pubitemid 23349366)
-
(1993)
Nature
, vol.366
, Issue.6453
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
7
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992;69:915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
8
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet. 2002;3:415-428.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
9
-
-
0030770835
-
Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
-
Chuang LS, Ian HI, Koh TW, et al. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science. 1997;277:1996-2000.
-
(1997)
Science
, vol.277
, pp. 1996-2000
-
-
Chuang, L.S.1
Ian, H.I.2
Koh, T.W.3
-
10
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
Baylin SB, Herman JG, Graff JR, et al. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res. 1998;72:141-196.
-
(1998)
Adv Cancer Res
, vol.72
, pp. 141-196
-
-
Baylin, S.B.1
Herman, J.G.2
Graff, J.R.3
-
11
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
DOI 10.1016/S0092-8674(00)81656-6
-
Okano M, Bell DW, Haber DA, et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999;99:247-257. (Pubitemid 29519904)
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
12
-
-
1542319832
-
Increased DNA Methyltransferase 1 (DNMT1) Protein Expression Correlates Significantly with Poorer Tumor Differentiation and Frequent DNA Hypermethylation of Multiple CpG Islands in Gastric Cancers
-
Etoh T, Kanai Y, Ushijima S, et al. Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am J Pathol. 2004;164:689-699. (Pubitemid 38364682)
-
(2004)
American Journal of Pathology
, vol.164
, Issue.2
, pp. 689-699
-
-
Etoh, T.1
Kanai, Y.2
Ushijima, S.3
Nakagawa, T.4
Nakanishi, Y.5
Sasako, M.6
Kitano, S.7
Hirohashi, S.8
-
13
-
-
43649106748
-
Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer
-
DOI 10.1038/sj.bjc.6604343, PII 6604343
-
Xing J, Stewart DJ, Gu J, et al. Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. Br J Cancer. 2008;98:1716-1722. (Pubitemid 351684678)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.10
, pp. 1716-1722
-
-
Xing, J.1
Stewart, D.J.2
Gu, J.3
Lu, C.4
Spitz, M.R.5
Wu, X.6
-
14
-
-
17144413410
-
DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis
-
Nakagawa T, Kanai Y, Ushijima S, et al. DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis. J Urol. 2005;173:1767-1771.
-
(2005)
J Urol
, vol.173
, pp. 1767-1771
-
-
Nakagawa, T.1
Kanai, Y.2
Ushijima, S.3
-
16
-
-
39149123532
-
Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma
-
Cohen Y, Merhavi-Shoham E, Avraham RB, et al. Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma. Exp Eye Res. 2008;86:201-206.
-
(2008)
Exp Eye Res
, vol.86
, pp. 201-206
-
-
Cohen, Y.1
Merhavi-Shoham, E.2
Avraham, R.B.3
-
17
-
-
0027962591
-
Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma
-
Greger V, Debus N, Lohmann D, et al. Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma. Hum Genet. 1994;94:491-496.
-
(1994)
Hum Genet
, vol.94
, pp. 491-496
-
-
Greger, V.1
Debus, N.2
Lohmann, D.3
-
18
-
-
0033566973
-
Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
-
De Marzo AM, Marchi VL, Yang ES, et al. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res. 1999;59:3855-3860.
-
(1999)
Cancer Res
, vol.59
, pp. 3855-3860
-
-
De Marzo, A.M.1
Marchi, V.L.2
Yang, E.S.3
-
19
-
-
0141995080
-
Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
-
Girault I, Tozlu S, Lidereau R, et al. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res. 2003;9:4415-4422.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4415-4422
-
-
Girault, I.1
Tozlu, S.2
Lidereau, R.3
-
20
-
-
0022506980
-
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
-
Friend SH, Bernards R, Rogelj S, et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature. 1986;323:643-646. (Pubitemid 16008560)
-
(1986)
Nature
, vol.323
, Issue.6089
, pp. 643-646
-
-
Friend, S.H.1
Bernards, R.2
Rogelj, S.3
-
21
-
-
27844480644
-
RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database
-
DOI 10.1186/1471-2156-6-53
-
Valverde JR, Alonso J, Palacios I, et al. RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database. BMC Genet. 2005;6:53. doi:10.1186/1471-2156-6-53. (Pubitemid 41645662)
-
(2005)
BMC Genetics
, vol.6
, pp. 53
-
-
Valverde, J.R.1
Alonso, J.2
Palacios, I.3
Pestana, A.4
-
22
-
-
0037313618
-
Coordinated regulation of life and death by RB
-
Chau BN, Wang JY. Coordinated regulation of life and death by RB. Nat Rev Cancer. 2003;3:130-138.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 130-138
-
-
Chau, B.N.1
Wang, J.Y.2
-
23
-
-
20144370134
-
Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma
-
Choy KW, Lee TC, Cheung KF, et al. Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. Neoplasia. 2005;7:200-206.
-
(2005)
Neoplasia
, vol.7
, pp. 200-206
-
-
Choy, K.W.1
Lee, T.C.2
Cheung, K.F.3
-
24
-
-
18444379044
-
Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
-
DOI 10.1038/sj.onc.1205446
-
Harada K, Toyooka S, Maitra A, et al. Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines. Oncogene. 2002;21:4345-4349. (Pubitemid 34753843)
-
(2002)
Oncogene
, vol.21
, Issue.27
, pp. 4345-4349
-
-
Harada, K.1
Toyooka, S.2
Maitra, A.3
Maruyama, R.4
Toyooka, K.O.5
Timmons, C.F.6
Tomlinson, G.E.7
Mastrangelo, D.8
Hay, R.J.9
Minna, J.D.10
Gazdar, A.F.11
-
25
-
-
0033153303
-
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
DOI 10.1093/nar/27.11.2291
-
Robertson KD, Uzvolgyi E, Liang G, et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res. 1999;27:2291-2298. (Pubitemid 29245646)
-
(1999)
Nucleic Acids Research
, vol.27
, Issue.11
, pp. 2291-2298
-
-
Robertson, K.D.1
Uzvolgyi, E.2
Liang, G.3
Talmadge, C.4
Sumegi, J.5
Gonzales, F.A.6
Jones, P.A.7
-
26
-
-
33748586754
-
Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells
-
DOI 10.1001/archopht.124.9.1269
-
Elison JR, Cobrinik D, Claros N, et al. Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells. Arch Ophthalmol. 2006;124:1269-1275. (Pubitemid 44379861)
-
(2006)
Archives of Ophthalmology
, vol.124
, Issue.9
, pp. 1269-1275
-
-
Elison, J.R.1
Cobrinik, D.2
Claros, N.3
Abramson, D.H.4
Lee, T.C.5
-
27
-
-
49649085534
-
Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma
-
Dalgard CL, Van Quill KR, O'Brien JM. Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. Clin Cancer Res. 2008;14:3113-3123.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3113-3123
-
-
Dalgard, C.L.1
Van Quill, K.R.2
O'Brien, J.M.3
-
28
-
-
33750590095
-
Inactivation of the p53 pathway in retinoblastoma
-
Laurie NA, Donovan SL, Shih CS, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444:61-66.
-
(2006)
Nature
, vol.444
, pp. 61-66
-
-
Laurie, N.A.1
Donovan, S.L.2
Shih, C.S.3
-
29
-
-
0028920604
-
The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor
-
Gabbara S, Bhagwat AS. The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor. Biochem J. 1995;307(pt 1):87-92.
-
(1995)
Biochem J
, vol.307
, Issue.PART 1
, pp. 87-92
-
-
Gabbara, S.1
Bhagwat, A.S.2
-
30
-
-
34347375106
-
Epigenetic drugs as pleiotropic agents in cancer treatment: Biomolecular aspects and clinical applications
-
DOI 10.1002/jcp.21066
-
Sigalotti L, Fratta E, Coral S, et al. Epigenetic drugs as pleiotropic agents in cancer treatment: biomolecular aspects and clinical applications. J Cell Physiol. 2007;212:330-344. (Pubitemid 47025622)
-
(2007)
Journal of Cellular Physiology
, vol.212
, Issue.2
, pp. 330-344
-
-
Sigalotti, L.1
Fratta, E.2
Coral, S.3
Cortini, E.4
Covre, A.5
Nicolay, H.J.M.6
Anzalone, L.7
Pezzani, L.8
Di Giacomo, A.M.9
Fonsatti, E.10
Colizzi, F.11
Altomonte, M.12
Calabro, L.13
Maio, M.14
-
31
-
-
56149090684
-
Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead
-
Mai A, Altucci L. Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead. Int J Biochem Cell Biol. 2009;41:199-213.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 199-213
-
-
Mai, A.1
Altucci, L.2
-
32
-
-
33846111256
-
Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer
-
Lin RK, Hsu HS, Chang JW, et al. Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer. 2007;55:205-213.
-
(2007)
Lung Cancer
, vol.55
, pp. 205-213
-
-
Lin, R.K.1
Hsu, H.S.2
Chang, J.W.3
|