메뉴 건너뛰기




Volumn 134, Issue 5, 2010, Pages 826-834

Overexpression of DNA methyltransferases 1, 3a, and 3b significantly correlates with retinoblastoma tumorigenesis

Author keywords

Biomarker; DNA methyltransferases; Immunohistochemistry; Retinoblastoma; Tumorigenesis

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; KI 67 ANTIGEN; DNA (CYTOSINE 5 ) METHYLTRANSFERASE 1; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; MESSENGER RNA;

EID: 78049515403     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPHGQ69FXDFWII     Document Type: Article
Times cited : (56)

References (32)
  • 1
    • 27644469013 scopus 로고    scopus 로고
    • Use of preclinical models to improve treatment of retinoblastoma
    • doi:10.1371/journal.pmed.0020332
    • Dyer MA, Rodriguez-Galindo C, Wilson MW. Use of preclinical models to improve treatment of retinoblastoma. PLoS Med. 2005;2:e332. doi:10.1371/journal. pmed.0020332.
    • (2005) PLoS Med , vol.2
    • Dyer, M.A.1    Rodriguez-Galindo, C.2    Wilson, M.W.3
  • 2
    • 0037299508 scopus 로고    scopus 로고
    • Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome
    • Lillington DM, Kingston JE, Coen PG, et al. Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome. Genes Chromosomes Cancer. 2003;36:121-128.
    • (2003) Genes Chromosomes Cancer , vol.36 , pp. 121-128
    • Lillington, D.M.1    Kingston, J.E.2    Coen, P.G.3
  • 3
    • 77649340617 scopus 로고    scopus 로고
    • Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas
    • published online December 11, doi:10.1016/j.humpath.2009.08.022
    • Mu G, Liu H, Zhou F, et al. Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomas [published online December 11, 2009]. Hum Pathol. 2010;41:493-502. doi:10.1016/j.humpath.2009.08.022.
    • (2009) Hum Pathol , vol.41 , pp. 493-502
    • Mu, G.1    Liu, H.2    Zhou, F.3
  • 4
    • 34249004558 scopus 로고    scopus 로고
    • One hit, two hits, three hits, more? genomic changes in the development of retinoblastoma
    • Corson TW, Gallie BL. One hit, two hits, three hits, more? genomic changes in the development of retinoblastoma. Genes Chromosomes Cancer. 2007;46:617-634.
    • (2007) Genes Chromosomes Cancer , vol.46 , pp. 617-634
    • Corson, T.W.1    Gallie, B.L.2
  • 5
    • 67650443984 scopus 로고    scopus 로고
    • Frontiers in the management of retinoblastoma
    • Lin P, O'Brien JM. Frontiers in the management of retinoblastoma. Am J Ophthalmol. 2009;148:192-198.
    • (2009) Am J Ophthalmol , vol.148 , pp. 192-198
    • Lin, P.1    O'Brien, J.M.2
  • 6
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • DOI 10.1038/366362a0
    • Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature. 1993;366:362-365. (Pubitemid 23349366)
    • (1993) Nature , vol.366 , Issue.6453 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 7
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992;69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 8
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. The fundamental role of epigenetic events in cancer. Nat Rev Genet. 2002;3:415-428.
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 9
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang LS, Ian HI, Koh TW, et al. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science. 1997;277:1996-2000.
    • (1997) Science , vol.277 , pp. 1996-2000
    • Chuang, L.S.1    Ian, H.I.2    Koh, T.W.3
  • 10
    • 0030846212 scopus 로고    scopus 로고
    • Alterations in DNA methylation: A fundamental aspect of neoplasia
    • Baylin SB, Herman JG, Graff JR, et al. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res. 1998;72:141-196.
    • (1998) Adv Cancer Res , vol.72 , pp. 141-196
    • Baylin, S.B.1    Herman, J.G.2    Graff, J.R.3
  • 11
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • DOI 10.1016/S0092-8674(00)81656-6
    • Okano M, Bell DW, Haber DA, et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 1999;99:247-257. (Pubitemid 29519904)
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 12
    • 1542319832 scopus 로고    scopus 로고
    • Increased DNA Methyltransferase 1 (DNMT1) Protein Expression Correlates Significantly with Poorer Tumor Differentiation and Frequent DNA Hypermethylation of Multiple CpG Islands in Gastric Cancers
    • Etoh T, Kanai Y, Ushijima S, et al. Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. Am J Pathol. 2004;164:689-699. (Pubitemid 38364682)
    • (2004) American Journal of Pathology , vol.164 , Issue.2 , pp. 689-699
    • Etoh, T.1    Kanai, Y.2    Ushijima, S.3    Nakagawa, T.4    Nakanishi, Y.5    Sasako, M.6    Kitano, S.7    Hirohashi, S.8
  • 13
    • 43649106748 scopus 로고    scopus 로고
    • Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer
    • DOI 10.1038/sj.bjc.6604343, PII 6604343
    • Xing J, Stewart DJ, Gu J, et al. Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer. Br J Cancer. 2008;98:1716-1722. (Pubitemid 351684678)
    • (2008) British Journal of Cancer , vol.98 , Issue.10 , pp. 1716-1722
    • Xing, J.1    Stewart, D.J.2    Gu, J.3    Lu, C.4    Spitz, M.R.5    Wu, X.6
  • 14
    • 17144413410 scopus 로고    scopus 로고
    • DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis
    • Nakagawa T, Kanai Y, Ushijima S, et al. DNA hypermethylation on multiple CpG islands associated with increased DNA methyltransferase DNMT1 protein expression during multistage urothelial carcinogenesis. J Urol. 2005;173:1767-1771.
    • (2005) J Urol , vol.173 , pp. 1767-1771
    • Nakagawa, T.1    Kanai, Y.2    Ushijima, S.3
  • 16
    • 39149123532 scopus 로고    scopus 로고
    • Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma
    • Cohen Y, Merhavi-Shoham E, Avraham RB, et al. Hypermethylation of CpG island loci of multiple tumor suppressor genes in retinoblastoma. Exp Eye Res. 2008;86:201-206.
    • (2008) Exp Eye Res , vol.86 , pp. 201-206
    • Cohen, Y.1    Merhavi-Shoham, E.2    Avraham, R.B.3
  • 17
    • 0027962591 scopus 로고
    • Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma
    • Greger V, Debus N, Lohmann D, et al. Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma. Hum Genet. 1994;94:491-496.
    • (1994) Hum Genet , vol.94 , pp. 491-496
    • Greger, V.1    Debus, N.2    Lohmann, D.3
  • 18
    • 0033566973 scopus 로고    scopus 로고
    • Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
    • De Marzo AM, Marchi VL, Yang ES, et al. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res. 1999;59:3855-3860.
    • (1999) Cancer Res , vol.59 , pp. 3855-3860
    • De Marzo, A.M.1    Marchi, V.L.2    Yang, E.S.3
  • 19
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I, Tozlu S, Lidereau R, et al. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res. 2003;9:4415-4422.
    • (2003) Clin Cancer Res , vol.9 , pp. 4415-4422
    • Girault, I.1    Tozlu, S.2    Lidereau, R.3
  • 20
    • 0022506980 scopus 로고
    • A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
    • Friend SH, Bernards R, Rogelj S, et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature. 1986;323:643-646. (Pubitemid 16008560)
    • (1986) Nature , vol.323 , Issue.6089 , pp. 643-646
    • Friend, S.H.1    Bernards, R.2    Rogelj, S.3
  • 21
    • 27844480644 scopus 로고    scopus 로고
    • RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database
    • DOI 10.1186/1471-2156-6-53
    • Valverde JR, Alonso J, Palacios I, et al. RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database. BMC Genet. 2005;6:53. doi:10.1186/1471-2156-6-53. (Pubitemid 41645662)
    • (2005) BMC Genetics , vol.6 , pp. 53
    • Valverde, J.R.1    Alonso, J.2    Palacios, I.3    Pestana, A.4
  • 22
    • 0037313618 scopus 로고    scopus 로고
    • Coordinated regulation of life and death by RB
    • Chau BN, Wang JY. Coordinated regulation of life and death by RB. Nat Rev Cancer. 2003;3:130-138.
    • (2003) Nat Rev Cancer , vol.3 , pp. 130-138
    • Chau, B.N.1    Wang, J.Y.2
  • 23
    • 20144370134 scopus 로고    scopus 로고
    • Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma
    • Choy KW, Lee TC, Cheung KF, et al. Clinical implications of promoter hypermethylation in RASSF1A and MGMT in retinoblastoma. Neoplasia. 2005;7:200-206.
    • (2005) Neoplasia , vol.7 , pp. 200-206
    • Choy, K.W.1    Lee, T.C.2    Cheung, K.F.3
  • 25
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • DOI 10.1093/nar/27.11.2291
    • Robertson KD, Uzvolgyi E, Liang G, et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res. 1999;27:2291-2298. (Pubitemid 29245646)
    • (1999) Nucleic Acids Research , vol.27 , Issue.11 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6    Jones, P.A.7
  • 26
    • 33748586754 scopus 로고    scopus 로고
    • Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells
    • DOI 10.1001/archopht.124.9.1269
    • Elison JR, Cobrinik D, Claros N, et al. Small molecule inhibition of HDM2 leads to p53-mediated cell death in retinoblastoma cells. Arch Ophthalmol. 2006;124:1269-1275. (Pubitemid 44379861)
    • (2006) Archives of Ophthalmology , vol.124 , Issue.9 , pp. 1269-1275
    • Elison, J.R.1    Cobrinik, D.2    Claros, N.3    Abramson, D.H.4    Lee, T.C.5
  • 27
    • 49649085534 scopus 로고    scopus 로고
    • Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma
    • Dalgard CL, Van Quill KR, O'Brien JM. Evaluation of the in vitro and in vivo antitumor activity of histone deacetylase inhibitors for the therapy of retinoblastoma. Clin Cancer Res. 2008;14:3113-3123.
    • (2008) Clin Cancer Res , vol.14 , pp. 3113-3123
    • Dalgard, C.L.1    Van Quill, K.R.2    O'Brien, J.M.3
  • 28
    • 33750590095 scopus 로고    scopus 로고
    • Inactivation of the p53 pathway in retinoblastoma
    • Laurie NA, Donovan SL, Shih CS, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 2006;444:61-66.
    • (2006) Nature , vol.444 , pp. 61-66
    • Laurie, N.A.1    Donovan, S.L.2    Shih, C.S.3
  • 29
    • 0028920604 scopus 로고
    • The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor
    • Gabbara S, Bhagwat AS. The mechanism of inhibition of DNA (cytosine-5-)-methyltransferases by 5-azacytosine is likely to involve methyl transfer to the inhibitor. Biochem J. 1995;307(pt 1):87-92.
    • (1995) Biochem J , vol.307 , Issue.PART 1 , pp. 87-92
    • Gabbara, S.1    Bhagwat, A.S.2
  • 31
    • 56149090684 scopus 로고    scopus 로고
    • Epi-drugs to fight cancer: From chemistry to cancer treatment, the road ahead
    • Mai A, Altucci L. Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead. Int J Biochem Cell Biol. 2009;41:199-213.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 199-213
    • Mai, A.1    Altucci, L.2
  • 32
    • 33846111256 scopus 로고    scopus 로고
    • Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer
    • Lin RK, Hsu HS, Chang JW, et al. Alteration of DNA methyltransferases contributes to 5'CpG methylation and poor prognosis in lung cancer. Lung Cancer. 2007;55:205-213.
    • (2007) Lung Cancer , vol.55 , pp. 205-213
    • Lin, R.K.1    Hsu, H.S.2    Chang, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.