Global DNA methylation in precancerous and cancerous lesions of the uterine cervix

Asian Pacific Journal of Cancer Prevention

Volumn 11, Issue 6, 2010, Pages 1741-1744

  Missaoui, Nabiha ^a,b,c   Hmissa, Sihem ^b,c   Dante, Robert ^a   Frappart, Lucien ^a,d  

^a CENTRE LÉON BÉRARD   (France)

^b Medicine Faculty   (Tunisia)

^c FARHAT HACHED HOSPITAL   (Tunisia)

^d Edouard Herriot University Hospital   (France)

Author keywords

Cancer; CIN; DNA hypomethylation; Uterine cervix

Indexed keywords

EID: 79956117582     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Bedford MT, van Helden PD (1987). Hypomethylation of DNA in pathological conditions of the human prostate. Cancer Res, 47, 5274-6.
2. Burgers WA, Blanchon L, Pradhan S, et al (2007). Viral oncoproteins target the DNA methyltransferases. Oncogene, 26, 1650-5.
3. Cuschieri K, Wentzensen N (2008). Human papillomavirus mRNA and p16 detection as biomarkers for the improved diagnosis of cervical neoplasia. Cancer Epidemiol Biomarkers Prev, 17, 2536-45.
4. de Capoa A, Musolino A, Della Rosa S, et al (2003). DNA demethylation is directly related to tumour progression: evidence in normal, pre-malignant and malignant cells from uterine cervix samples. Oncol Rep, 10, 545-9.
5. Dell G, Gaston K (2001). Human papillomaviruses and their role in cervical cancer. Cell Mol Life Sci, 58, 1923-42.
6. Ehrlich M, Hopkins NE, Jiang G, et al (2003). Satellite DNA hypomethylation in karyotyped Wilms tumors. Cancer Genet Cytogenet, 141, 97-105.
7. Ehrlich M (2002). DNA methylation in cancer: too much, but also too little. Oncogene, 21, 5400-13.
8. Ehrlich M, Jiang G, Fiala E, et al (2002). Hypomethylation and hypermethylation of DNA in Wilms tumors. Oncogene, 21, 6694-702.
9. Florl AR, Steinhoff C, Muller M, et al (2004). Coordinate hypermethylation at specific genes in prostate carcinoma precedes LINE-1 hypomethylation. Br J Cancer, 91, 985-94.
10. Fraga MF, Uriol E, Borja Diego L, et al (2002). Highperformance capillary electrophoretic method for the quantification of 5-methyl 2'-deoxycytidine in genomic DNA: application to plant, animal and human cancer tissues. Electrophoresis, 23, 1677-81.
11. Gama-Sosa MA, Slagel VA, Trewyn RW, et al (1983). The 5-methylcytosine content of DNA from human tumors. Nucleic Acids Res, 11, 6883-94.
12. Ghabreau L, Roux JP, Niveleau A, et al (2004). Correlation between the DNA global methylation status and progesterone receptor expression in normal endometrium, endometrioid adenocarcinoma and precursors. Virchows Arch, 445, 129-34.
13. Goyal R, Reinhardt R, Jeltsch A (2006). Accuracy of DNA methylation pattern preservation by the Dnmt1 methyltransferase. Nucleic Acids Res, 34, 1182-8.
14. Kim YI, Giuliano A, Hatch KD, et al (1994). Global DNA hypomethylation increases progressively in cervical dysplasia and carcinoma. Cancer, 74, 893-9.
15. Klaes R, Friedrich T, Spitkovsky D, et al (2001). Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri. Int J Cancer, 92, 276-84.
16. Lin CH, Hsieh SY, Sheen IS, et al (2001). Genome-wide hypomethylation in hepatocellular carcinogenesis. Cancer Res, 61, 4238-43.
17. Missaoui N, Hmissa S, Frappart L, et al (2006). p16INK4A overexpression and HPV infection in uterine cervix adenocarcinoma. Virchows Arch, 448, 597-603.
18. Missaoui N, Trabelsi A, Hmissa S, et al (2010). p16INK4A overexpression in precancerous and cancerous lesions of the uterine cervix in Tunisian women. Pathol Res Pract, 206, 550-5.
19. Ostor AG (1993). Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol, 12, 186-92.
20. Parkin DM (2006). The evolution of the population-based cancer registry. Nat Rev Cancer, 6, 603-12.
21. Perrin D, Ballestar E, Fraga MF, et al (2007). Specific hypermethylation of LINE-1 elements during abnormal overgrowth and differentiation of human placenta. Oncogene, 26, 2518-24.
22. Piyathilake CJ, Azrad M, Jhala D, et al (2006). Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis. Cancer Biomark, 2, 259-66.
23. Tavassoli FA, Devilee P (2003). Tumours of the breast and female genital organs. IARC, Lyon
24. Tost J (2009). DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Methods Mol Biol, 507, 3-20.
25. Wahlfors J, Hiltunen H, Heinonen K, et al (1992). Genomic hypomethylation in human chronic lymphocytic leukemia. Blood, 80, 2074-80.
26. Wentzensen N, Bergeron C, Cas F, et al (2005). Evaluation of a nuclear score for p16INK4a stained cervical squamous cells in liquid based cytology samples. Cancer, 105, 461-7.
27. Widschwendter M, Jiang G, Woods C, et al (2004). DNA hypomethylation and ovarian cancer biology. Cancer Res, 64, 4472-80.
28. Yang HJ, Liu VW, Wang Y, et al (2006). Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data. BMC Cancer, 6, 212.
29. zur Hausen H (2000). Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst, 92, 690-8.
30. zur Hausen H (2001). Cervical carcinoma and human papillomavirus: on the road to preventing a major human cancer. J Natl Cancer Inst, 93, 252-3.
31. zur Hausen H (2002). Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer, 2, 342-50.