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Volumn 404, Issue 6781, 2000, Pages 1003-1007

CpG methylation is maintained in human cancer cells lacking DNMT1

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE;

EID: 0034720284     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35010000     Document Type: Article
Times cited : (382)

References (30)
  • 2
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones, P. A. & Laird, P. W. Cancer epigenetics comes of age. Nature Genet. 21, 163-167 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 3
    • 0030009868 scopus 로고    scopus 로고
    • Mechanisms for the involvement of DNA methylation in colon carcinogenesis
    • Schmutte, C., Yang, A. S., Nguyen, T. T. Beart, R. W. & Jones, P. A. Mechanisms for the involvement of DNA methylation in colon carcinogenesis. Cancer Res. 56, 2375-2381 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 2375-2381
    • Schmutte, C.1    Yang, A.S.2    Nguyen, T.T.3    Beart, R.W.4    Jones, P.A.5
  • 4
    • 0033563083 scopus 로고    scopus 로고
    • CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression
    • Eads, C. A. et al. CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. Cancer Res. 59, 2302-2306 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 2302-2306
    • Eads, C.A.1
  • 5
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T. H. & Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926 (1992).
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 6
    • 0033578407 scopus 로고    scopus 로고
    • Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues
    • Hsu, D. W. et al. Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues. Proc. Natl Acad. Sci. USA 96, 9751-9756 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 9751-9756
    • Hsu, D.W.1
  • 7
    • 0033533612 scopus 로고    scopus 로고
    • 14-3σ is required to prevent mitotic catastrophe after DNA damage
    • Chan, T. A., Hermeking, H., Lengauer, C., Kinzler, K. W. & Vogelstein, B. 14-3σ is required to prevent mitotic catastrophe after DNA damage. Nature 401, 616-620 (1999).
    • (1999) Nature , vol.401 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 8
    • 0030983076 scopus 로고    scopus 로고
    • DNA methylation and genetic instability in colorectal cancer cells
    • Lengauer, C., Kinzler, K. W. & Vogelstein, B. DNA methylation and genetic instability in colorectal cancer cells. Proc. Natl Acad. Sci. USA 94, 2545-2550 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 2545-2550
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 10
    • 0031004175 scopus 로고    scopus 로고
    • Genetic instability in colorectal cancers
    • Lengauer, C., Kinzler, K. W. & Vogelstein, B. Genetic instability in colorectal cancers. Nature 386, 623-627 (1997).
    • (1997) Nature , vol.386 , pp. 623-627
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 11
    • 0030868694 scopus 로고    scopus 로고
    • Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation
    • Graff, J. R., Herman, J. G., Myohanen, S., Baylin, S. B. & Vertino, P. M. Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation. J. Biol. Chem. 272, 22322-22329 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 22322-22329
    • Graff, J.R.1    Herman, J.G.2    Myohanen, S.3    Baylin, S.B.4    Vertino, P.M.5
  • 12
    • 0019202657 scopus 로고
    • Quantitative reversed-phase high performance liquid chromatographic determination of major and modified deoxyribonucleosides in DNA
    • Kuo, K. C., McCune, K. A., Gehrke, C. W., Midgett, R. & Ehrlich, M. Quantitative reversed-phase high performance liquid chromatographic determination of major and modified deoxyribonucleosides in DNA. Nucleic Acids Res. 8, 4763-4776 (1980).
    • (1980) Nucleic Acids Res. , vol.8 , pp. 4763-4776
    • Kuo, K.C.1    McCune, K.A.2    Gehrke, C.W.3    Midgett, R.4    Ehrlich, M.5
  • 13
    • 0023848637 scopus 로고
    • Reduced genomic 5-methylcytosine content in human colonic neoplasia
    • Feinberg, A. P., Gehrke, C. W., Kuo, K. C. & Ehrlich, M. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res. 48, 1159-1161 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 1159-1161
    • Feinberg, A.P.1    Gehrke, C.W.2    Kuo, K.C.3    Ehrlich, M.4
  • 14
    • 0026546877 scopus 로고
    • A genomic sequencing protocol that yields a positive display of 5- methylcytosine residues in individual DNA strands
    • Frommer, M. et al. A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands. Proc. Natl Acad. Sci. USA 89, 1827-1831 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 1827-1831
    • Frommer, M.1
  • 15
    • 0028033270 scopus 로고
    • Mutations and altered expression of p16INK4 in human cancer
    • Okamoto, A. et al. Mutations and altered expression of p16INK4 in human cancer. Proc. Natl Acad. Sci. USA 91, 11045-11049 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11045-11049
    • Okamoto, A.1
  • 16
    • 0033558192 scopus 로고    scopus 로고
    • Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers
    • Bachman, K. E. et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers. Cancer Res. 59, 798-802 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 798-802
    • Bachman, K.E.1
  • 17
    • 0020582853 scopus 로고
    • On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs
    • Santi, D. V., Garrett, C. E. & Barr, P. J. On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs. Cell 33, 9-10 (1983).
    • (1983) Cell , vol.33 , pp. 9-10
    • Santi, D.V.1    Garrett, C.E.2    Barr, P.J.3
  • 18
    • 0000418476 scopus 로고
    • Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine
    • Santi, D. V., Norment, A. & Garrett, C. E. Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine. Proc. Natl Acad. Sci. USA 81, 6993-6997 (1984).
    • (1984) Proc. Natl Acad. Sci. USA , vol.81 , pp. 6993-6997
    • Santi, D.V.1    Norment, A.2    Garrett, C.E.3
  • 19
    • 0028151343 scopus 로고
    • Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
    • Juttermann, R., Li, E. & Jaenisch, R. Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc. Natl Acad. Sci. USA 91, 11797-11801 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 11797-11801
    • Juttermann, R.1    Li, E.2    Jaenisch, R.3
  • 20
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano, M., Xie, S. & Li, E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nature Genet. 19, 219-220 (1998).
    • (1998) Nature Genet. , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 21
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano, M., Bell, D. W., Haber, D. A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999).
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 22
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C. & Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 366, 362-365 (1993).
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 23
    • 0029803192 scopus 로고    scopus 로고
    • De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells
    • Lei, H. et al. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 122, 3195-3205 (1996).
    • (1996) Development , vol.122 , pp. 3195-3205
    • Lei, H.1
  • 24
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
    • Xu, G. L. et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402, 187-191 (1999).
    • (1999) Nature , vol.402 , pp. 187-191
    • Xu, G.L.1
  • 25
    • 0032478271 scopus 로고    scopus 로고
    • A simplified system for generating recombinant adenoviruses
    • He, T. C. et al. A simplified system for generating recombinant adenoviruses. Proc. Natl Acad. Sci. USA 95, 2509-2514 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 2509-2514
    • He, T.C.1
  • 26
    • 0029973718 scopus 로고    scopus 로고
    • De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
    • Vertino, P. M., Yen, R. W., Gao, J. & Baylin, S. B. De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol. Cell. Biol. 16, 4555-4565 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4555-4565
    • Vertino, P.M.1    Yen, R.W.2    Gao, J.3    Baylin, S.B.4
  • 27
    • 0028650742 scopus 로고
    • Human satellites 2 and 3
    • Jeanpierre, M. Human satellites 2 and 3. Ann. Genet. 37, 163-171 (1994).
    • (1994) Ann. Genet. , vol.37 , pp. 163-171
    • Jeanpierre, M.1
  • 28
    • 0033563165 scopus 로고    scopus 로고
    • Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
    • Toyota, M. et al. Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification. Cancer Res. 59, 2307-2312 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 2307-2312
    • Toyota, M.1
  • 30
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the re- expression of genes silenced in cancer
    • Cameron, E. E., Bachman, K. E., Myohanen, S., Herman, J. G. & Baylin, S. B. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nature Genet. 21, 103-107 (1999).
    • (1999) Nature Genet. , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.