Bcl6 mediates the development of T follicular helper cells

Science

Volumn 325, Issue 5943, 2009, Pages 1001-1005

  Nurieva, Roza I ^a   Chung, Yeonseok ^a   Martinez, Gustavo J ^a   Yang, Xuexian O ^a   Tanaka, Shinya ^a   Matskevitch, Tatyana D ^a   Wang, Yi Hong ^a   Dong, Chen ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 21; INTERLEUKIN 6; PROTEIN BCL 6;

BIOLOGICAL ANALYSIS; DNA; GENE EXPRESSION; GENETIC ANALYSIS; REACTION KINETICS;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EFFECTOR CELL; GERMINAL CENTER; HELPER CELL; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; ANTIBODY FORMATION; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CYTOKINES; DNA-BINDING PROTEINS; GERMINAL CENTER; IMMUNOGLOBULINS; INTERLEUKIN-6; INTERLEUKINS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TRANSCRIPTION FACTORS;

EID: 69249101229     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1176676     Document Type: Article

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19. We thank R. Dalla-Favera for the generous gift of Bcl6-deficient mice, K. Murphy for the retrovirus vector, and members of the Dong laboratory for their help. The work is supported by research grants from NIH (to C.D. and R.I.N.), M. D. Anderson Cancer Center, and Leukemia and Lymphoma Society (to C.D.). G.J.M. is a Schissler Foundation Fellow in cancer research. Y.C. is a recipient of a postdoctoral fellowship from the Korea Science and Engineering Foundation. R.N. is a recipient of a Scientist Development Grant from the American Heart Association, and C.D. is a Leukemia and Lymphoma Society Scholar and a Trust Fellow of the M. D. Anderson Cancer Center.