Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development

Journal of Immunology

Volumn 187, Issue 5, 2011, Pages 2322-2328

  Bassil, Ribal ^a   Zhu, Bing ^a   Lahoud, Youmna ^a   Riella, Leonardo V ^b,c   Yagita, Hideo ^d   Elyaman, Wassim ^a   Khoury, Samia J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; JANUS KINASE 3; LIGAND; MONOCLONAL ANTIBODY; NOTCH DELTA LIKE 4 LIGAND; NOTCH RECEPTOR; STAT5 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; FEMALE; IMMUNE RESPONSE; IMMUNOTHERAPY; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; LYMPHOCYTOPOIESIS; MOLECULAR INTERACTION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T CELL DEPLETION; TH1 CELL; TH17 CELL; TH2 CELL;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL SEPARATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; FLOW CYTOMETRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 80052685578     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100725     Document Type: Article

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