Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis

Immunity

Volumn 33, Issue 5, 2010, Pages 685-698

  Gómez del Arco, Pablo ^a,b,c   Kashiwagi, Mariko ^c   Jackson, Audrey F ^c   Naito, Taku ^c,h   Zhang, Jiangwen ^d   Liu, Feifei ^c   Kee, Barbara ^e   Vooijs, Marc ^f   Radtke, Freddy ^g   Redondo, Juan Miguel ^a   Georgopoulos, Katia ^c  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD UNIVERSITY   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f MAASTRICHT UNIVERSITY   (Netherlands)

^g UNIVERSITY OF LAUSANNE   (Switzerland)

^h RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; NOTCH1 RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MATURATION; LEUKEMIA CELL; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

ANIMALS; EPIGENOMICS; GENE EXPRESSION REGULATION, LEUKEMIC; GENETIC LOCI; IKAROS TRANSCRIPTION FACTOR; LYMPHOCYTE ACTIVATION; MICE; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 78650213618     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2010.11.008     Document Type: Article

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