Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell-dependent mechanism

Journal of Clinical Investigation

Volumn 112, Issue 11, 2003, Pages 1741-1750

  Wong, Kenneth K ^a   Carpenter, Matthew J ^a   Young, Lesley L ^b   Walker, Susan J ^a   McKenzie, Grahame ^b   Rust, Alyson J ^b   Ward, George ^b   Packwood, Laura ^a   Wahl, Karen ^c   Delriviere, Luc ^d   Hoyne, Gerard ^c   Gibbs, Paul ^d   Champion, Brian R ^b   Lamb, Jonathan R ^c   Dallman, Margaret J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b Celldex Therapeutics Inc   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD8 ANTIGEN; DELTA1 PROTEIN; GAMMA INTERFERON; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN; NOTCH RECEPTOR; PROTEIN; TRANSPLANTATION ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL RENEWAL; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; GENE EXPRESSION; GRAFT REJECTION; HEART TRANSPLANTATION; HEMATOPOIETIC STEM CELL; IMMUNE RESPONSE; IMMUNOGENICITY; LYMPHOCYTE DEPLETION; LYMPHOCYTE DIFFERENTIATION; NONHUMAN; PERIPHERAL IMMUNE RESPONSE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; TRANSPLANTATION; TRANSPLANTATION TOLERANCE;

ANIMALS; ANTIGEN-PRESENTING CELLS; APOPTOSIS; CALCIUM-BINDING PROTEINS; CD8-POSITIVE T-LYMPHOCYTES; CHO CELLS; CRICETINAE; GRAFT REJECTION; HISTOCOMPATIBILITY ANTIGENS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON TYPE II; INTERLEUKIN-10; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; PROTEINS; RECEPTOR, NOTCH2; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0347951391     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200318020     Document Type: Article

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