IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells

Nature Immunology

Volumn 9, Issue 12, 2008, Pages 1347-1355

  Dardalhon, Valérie ^a   Awasthi, Amit ^a   Kwon, Hyoung ^a   Galileos, George ^a   Gao, Wenda ^b   Sobel, Raymond A ^c   Mitsdoerffer, Meike ^a   Strom, Terry B ^b   Elyaman, Wassim ^a   Ho, I Cheng ^a   Khoury, Samia ^a   Oukka, Mohamed ^a   Kuchroo, Vijay K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45RB ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 9; RAG1 PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; HELPER CELL; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; IMMUNOREGULATION; INFLAMMATION; MOUSE; NEURITIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; FORKHEAD TRANSCRIPTION FACTORS; GATA3 TRANSCRIPTION FACTOR; INTERLEUKIN-10; INTERLEUKIN-4; INTERLEUKIN-9; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; STAT6 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 56349093347     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1677     Document Type: Article

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