Subversion of the T/B lineage decision in the thymus by Lunatic Fringe-mediated inhibition of Notch-1

Immunity

Volumn 15, Issue 2, 2001, Pages 225-236

  Koch, Ute ^a,b   Lacombe, Tyler A ^a,b   Holland, Dianne ^a,b   Bowman, Jennifer L ^a,b   Cohen, Brenda L ^a,b   Egan, Sean E ^a,b   Guidos, Cynthia J ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LUNATIC FRINGE PROTEIN; MEMBRANE RECEPTOR; NOTCH1 RECEPTOR; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL FATE; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; ECTOPIC TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; STEM CELL; T LYMPHOCYTE; THYMOCYTE; THYMUS; TRANSGENIC MOUSE;

EID: 0034869258     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(01)00189-3     Document Type: Article

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15. - T-cells bearing αβ TCR
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34. The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD
35. Fringe modulates Notch-ligand interactions
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