-
1
-
-
0029150110
-
Immunologie self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologie self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151.
-
(1995)
J. Immunol.
, vol.155
, pp. 1151
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
2
-
-
0029788211
-
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation
-
Asano, M., M. Toda, N. Sakaguchi, and S. Sakaguchi. 1996. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J. Exp. Med. 184:387.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 387
-
-
Asano, M.1
Toda, M.2
Sakaguchi, N.3
Sakaguchi, S.4
-
3
-
-
0031647622
-
+ naturally anergic and suppressive T cells: Induction of autoimmune disease by breaking their anergic/suppressive state
-
+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10:1969.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
5
-
-
0031939403
-
+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
-
+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160:1212.
-
(1998)
J. Immunol.
, vol.160
, pp. 1212
-
-
Suri-Payer, E.1
Amar, A.Z.2
Thornton, A.M.3
Shevach, E.M.4
-
6
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287
-
-
Thomton, A.M.1
Shevach, E.M.2
-
9
-
-
0035320679
-
+ regulatory T cells induced by an agonist self-peptide
-
+ regulatory T cells induced by an agonist self-peptide. Nat. Immunol. 2:301.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 301
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
Petrone, A.L.4
Holenbeck, A.E.5
Lerman, M.A.6
Naji, A.7
Caton, A.J.8
-
16
-
-
0037220923
-
+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice
-
+ regulatory T cells suppress differentiation and functions of Th1 and Th2 cells, Leishmania major infection, and colitis in mice. J. Immunol. 170:394.
-
(2003)
J. Immunol.
, vol.170
, pp. 394
-
-
Xu, D.1
Liu, H.2
Komai-Koma, M.3
Campbell, C.4
McSharry, C.5
Alexander, J.6
Liew, F.Y.7
-
17
-
-
0036838536
-
+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
-
+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169:4712.
-
(2002)
J. Immunol.
, vol.169
, pp. 4712
-
-
Kohm, A.P.1
Carpentier, P.A.2
Anger, H.A.3
Miller, S.D.4
-
18
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice: Implications for the nonredundant function of IL-2
-
Malek, T. R., A. Yu, V. Vincek, P. Scibelli, and L. Kong. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rβ-deficient mice: implications for the nonredundant function of IL-2. Immunity 17:167.
-
(2002)
Immunity
, vol.17
, pp. 167
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
24
-
-
0035525739
-
+ cells: A naturally occurring population of regulatory T cells
-
+ cells: a naturally occurring population of regulatory T cells. Blood 98:2736.
-
(2001)
Blood
, vol.98
, pp. 2736
-
-
Ng, W.F.1
Duggan, P.J.2
Ponchel, F.3
Matarese, O.4
Lombardi, O.5
Edwards, A.D.6
Isaacs, J.D.7
Lechler, R.I.8
-
28
-
-
0033928257
-
T-regulatory 1 cells: A novel subset of CD4 T cells with immunoregulatory properties
-
Levings, M. K., and M. G. Roncarolo. 2000. T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties. J. Allergy Clin. Immunol. 106:S109.
-
(2000)
J. Allergy Clin. Immunol.
, vol.106
-
-
Levings, M.K.1
Roncarolo, M.G.2
-
30
-
-
0031578938
-
Oral administration of myelin induces antigen-specific TGF-β1 secreting T cells in patients with multiple sclerosis
-
Hafler, D. A., S. C. Kent, M. J. Pietrusewicz, S. J. Khoury, H. L. Weiner, and H. Fukaura. 1997. Oral administration of myelin induces antigen-specific TGF-β1 secreting T cells in patients with multiple sclerosis. Ann. NY Acad. Sci. 835:120.
-
(1997)
Ann. NY Acad. Sci.
, vol.835
, pp. 120
-
-
Hafler, D.A.1
Kent, S.C.2
Pietrusewicz, M.J.3
Khoury, S.J.4
Weiner, H.L.5
Fukaura, H.6
-
31
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198:1875.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
32
-
-
1642299050
-
PKCθ signals activation versus tolerance in vivo
-
Berg-Brown, N. N., M. A. Gronski, R. G. Jones, A. R. Elford, E. K. Deenick, B. Odermatt, D. R. Littman, and P. S. Ohashi. 2004. PKCθ signals activation versus tolerance in vivo. J. Exp. Med. 199:743.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 743
-
-
Berg-Brown, N.N.1
Gronski, M.A.2
Jones, R.G.3
Elford, A.R.4
Deenick, E.K.5
Odermatt, B.6
Littman, D.R.7
Ohashi, P.S.8
-
33
-
-
0034724201
-
NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ
-
Coudronniere, N., M. Villalba, N. Englund, and A. Altman. 2000. NF-κB activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-θ. Proc. Natl. Acad. Sci. USA 97:3394.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3394
-
-
Coudronniere, N.1
Villalba, M.2
Englund, N.3
Altman, A.4
-
34
-
-
0034672054
-
The physical association of protein kinase Cθ with a lipid raft-associated inhibitor of κB factor kinase (IKK) complex plays a role in the activation of the NF-κB cascade by TCR and CD28
-
Khoshnan, A., D. Bae, C. A. Tindell, and A. E. Nel. 2000. The physical association of protein kinase Cθ with a lipid raft-associated inhibitor of κB factor kinase (IKK) complex plays a role in the activation of the NF-κB cascade by TCR and CD28. J. Immunol. 165:6933.
-
(2000)
J. Immunol.
, vol.165
, pp. 6933
-
-
Khoshnan, A.1
Bae, D.2
Tindell, C.A.3
Nel, A.E.4
-
35
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., H. Reddy, M. Caivano, and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95.
-
(2000)
Biochem. J.
, vol.351
, pp. 95
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
36
-
-
12444296237
-
-
Inhibitor of T-cell activation. International patent application WO 03/004612 A2, 02.07.2002. Yale University, New Haven
-
Ghosh, S., and F. D'Acquisto. 2003. Inhibitor of T-cell activation. International patent application WO 03/004612 A2, 02.07.2002. Yale University, New Haven.
-
(2003)
-
-
Ghosh, S.1
D'Acquisto, F.2
-
37
-
-
0034613767
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
-
+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192:1213.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 1213
-
-
Jonuleit, H.1
Schmitt, E.2
Schuler, G.3
Knop, J.4
Enk, A.H.5
-
38
-
-
0036086232
-
+ regulatory T cells
-
+ regulatory T cells. Eur. J. Immunol. 32:1621.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1621
-
-
Taams, L.S.1
Vukmanovic-Stejic, M.2
Smith, J.3
Dunne, P.J.4
Fletcher, J.M.5
Plunkett, F.J.6
Ebeling, S.B.7
Lombardi, G.8
Rustin, M.H.9
Bijlsma, J.W.10
-
39
-
-
0036345337
-
Origin of regulatory T cells with known specificity for antigen
-
Apostolou, I., A. Sarukhan, L. Klein, and H. von Boehmer. 2002. Origin of regulatory T cells with known specificity for antigen. Nat. Immunol. 3:756.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 756
-
-
Apostolou, I.1
Sarukhan, A.2
Klein, L.3
Von Boehmer, H.4
-
40
-
-
0038044861
-
- T cells to acquire regulatory cell function
-
- T cells to acquire regulatory cell function. Blood 101:5076.
-
(2003)
Blood
, vol.101
, pp. 5076
-
-
Chen, Z.M.1
O'Shaughnessy, M.J.2
Gramaglia, I.3
Panoskaltsis-Mortari, A.4
Murphy, W.J.5
Narula, S.6
Roncarolo, M.G.7
Blazar, B.R.8
-
42
-
-
0036687184
-
Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines
-
Bacchetta, R., C. Sartirana, M. K. Levings, C. Bordignon, S. Narula, and M. G. Roncarolo. 2002. Growth and expansion of human T regulatory type 1 cells are independent from TCR activation but require exogenous cytokines. Eur. J. Immunol. 32:2237.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2237
-
-
Bacchetta, R.1
Sartirana, C.2
Levings, M.K.3
Bordignon, C.4
Narula, S.5
Roncarolo, M.G.6
-
43
-
-
0037018104
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J. Exp. Med. 195:603.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 603
-
-
Barrat, F.J.1
Cua, D.J.2
Boonstra, A.3
Richards, D.F.4
Crain, C.5
Savelkoul, H.F.6
De Waal-Malefyt, R.7
Coffman, R.L.8
Hawrylowicz, C.M.9
O'Garra, A.10
-
44
-
-
0035339884
-
IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells
-
Levings, M. K., R. Sangregorio, F. Galbiati, S. Squadrone, R. de Waal Malefyt, and M. G. Roncarolo. 2001. IFN-α and IL-10 induce the differentiation of human type 1 T regulatory cells. J. Immunol. 166:5530.
-
(2001)
J. Immunol.
, vol.166
, pp. 5530
-
-
Levings, M.K.1
Sangregorio, R.2
Galbiati, F.3
Squadrone, S.4
De Waal Malefyt, R.5
Roncarolo, M.G.6
-
45
-
-
0037131969
-
+ T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from type 1 T regulatory cells
-
+ T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from type 1 T regulatory cells. J. Exp. Med. 196:1335.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 1335
-
-
Levings, M.K.1
Sangregorio, R.2
Sartirana, C.3
Moschin, A.L.4
Battaglia, M.5
Orban, P.C.6
Roncarolo, M.G.7
-
46
-
-
0035806323
-
+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
-
+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function. J. Exp. Med. 193:1295.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1295
-
-
Levings, M.K.1
Sangregorio, R.2
Roncarolo, M.G.3
-
47
-
-
0036467522
-
+ regulatory T cells prevent graft rejection: CTLA-4- And IL-10-dependent immunoregulation of alloresponses
-
+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponses. J. Immunol. 168:1080.
-
(2002)
J. Immunol.
, vol.168
, pp. 1080
-
-
Kingsley, C.I.1
Karim, M.2
Bushell, A.R.3
Wood, K.J.4
-
48
-
-
0036791004
-
- regulatory T cells
-
- regulatory T cells. Proc. Natl. Acad. Sci. USA 99:13031.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13031
-
-
Lehmann, J.1
Huehn, J.2
De La Rosa, M.3
Maszyna, F.4
Kretschmer, U.5
Krenn, V.6
Brunner, M.7
Scheffold, A.8
Hamann, A.9
-
50
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez, F., S. D. Hurst, R. L. Coffman, and H. Groux. 2000. T regulatory cells 1 inhibit a Th2-specific response in vivo. J. Immunol. 165:4848.
-
(2000)
J. Immunol.
, vol.165
, pp. 4848
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
51
-
-
0035186416
-
Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells
-
Weiner, H. L. 2001. Induction and mechanism of action of transforming growth factor-β-secreting Th3 regulatory cells. Immunol Rev. 182:207.
-
(2001)
Immunol Rev.
, vol.182
, pp. 207
-
-
Weiner, H.L.1
-
53
-
-
0037099733
-
+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells
-
+ regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells. J. Exp. Med. 196:247.
-
(2002)
J. Exp. Med.
, vol.196
, pp. 247
-
-
Dieckmann, D.1
Bruett, C.H.2
Ploettner, H.3
Lutz, M.B.4
Schuler, G.5
-
55
-
-
0035181582
-
Type 1 T regulatory cells
-
Roncarolo, M. G., R. Bacchetta, C. Bordignon, S. Narula, and M. K. Levings. 2001. Type 1 T regulatory cells. Immunol. Rev. 182:68.
-
(2001)
Immunol. Rev.
, vol.182
, pp. 68
-
-
Roncarolo, M.G.1
Bacchetta, R.2
Bordignon, C.3
Narula, S.4
Levings, M.K.5
-
57
-
-
0037013930
-
Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation
-
Gorelik, L., S. Constant, and R. A. Flavell. 2002. Mechanism of transforming growth factor β-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195:1499.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
58
-
-
0033623339
-
TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression
-
Heath, V. L., E. E. Murphy, C. Crain, M. G. Tomlinson, and A. O'Garra. 2000. TGF-β1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression. Eur. J. Immunol. 30:2639.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2639
-
-
Heath, V.L.1
Murphy, E.E.2
Crain, C.3
Tomlinson, M.G.4
O'Garra, A.5
-
59
-
-
0034327176
-
Cutting edge: TGF-β inhibits Th type 2 development through inhibition of GATA-3 expression
-
Gorelik, L., P. E. Fields, and R. A. Flavell. 2000. Cutting edge: TGF-β inhibits Th type 2 development through inhibition of GATA-3 expression. J. Immunol. 165:4773.
-
(2000)
J. Immunol.
, vol.165
, pp. 4773
-
-
Gorelik, L.1
Fields, P.E.2
Flavell, R.A.3
-
60
-
-
18844473151
-
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
-
Sun, Z., C. W. Arendt, W. Ellmeier, E. M. Schaeffer, M. J. Sunshine, L. Gandhi, J. Annes, D. Petrzilka, A. Kupfer, P. L. Schwartzberg, and D. R. Littman. 2000. PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes. Nature 404:402.
-
(2000)
Nature
, vol.404
, pp. 402
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
Schaeffer, E.M.4
Sunshine, M.J.5
Gandhi, L.6
Annes, J.7
Petrzilka, D.8
Kupfer, A.9
Schwartzberg, P.L.10
Littman, D.R.11
-
61
-
-
0242708772
-
Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling
-
Jun, J. E., and C. C. Goodnow. 2003. Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling. Nat. Immunol. 4:1057.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 1057
-
-
Jun, J.E.1
Goodnow, C.C.2
-
62
-
-
85047682875
-
Protein kinase Cθ in T cell activation
-
Isakov, N., and A. Altman. 2002. Protein kinase Cθ in T cell activation. Annu. Rev. Immunol. 20:761.
-
(2002)
Annu. Rev. Immunol.
, vol.20
, pp. 761
-
-
Isakov, N.1
Altman, A.2
-
63
-
-
0035870086
-
Differential NF-κb and IκB gene expression during development of cardiac allograft rejection versus CD154 monoclonal antibody-induced tolerance
-
Csizmadia, V., W. Gao, S. A. Hancock, J. B. Rottman, Z. Wu, L. A. Turka, U. Siebenlist, and W. W. Hancock. 2001. Differential NF-κb and IκB gene expression during development of cardiac allograft rejection versus CD154 monoclonal antibody-induced tolerance. Transplantation 71:835.
-
(2001)
Transplantation
, vol.71
, pp. 835
-
-
Csizmadia, V.1
Gao, W.2
Hancock, S.A.3
Rottman, J.B.4
Wu, Z.5
Turka, L.A.6
Siebenlist, U.7
Hancock, W.W.8
-
64
-
-
0029038108
-
Deoxyspergualin inhibits κ light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-κB activation
-
Tepper, M. A., S. G. Nadler, J. M. Esselstyn, and K. G. Sterbenz. 1995. Deoxyspergualin inhibits κ light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-κB activation. J. Immunol. 155:2427.
-
(1995)
J. Immunol.
, vol.155
, pp. 2427
-
-
Tepper, M.A.1
Nadler, S.G.2
Esselstyn, J.M.3
Sterbenz, K.G.4
-
65
-
-
0037850570
-
The immune decision toward allograft tolerance in non-human primates requires early inhibition of innate immunity and induction of immune regulation
-
Hutchings, A., J. Wu, C. Asiedu, W. Hubbard, D. Eckhoff, J. Contreras, F. T. Thomas, D. Neville, and J. M. Thomas. 2003. The immune decision toward allograft tolerance in non-human primates requires early inhibition of innate immunity and induction of immune regulation. Transplant Immunol. 11:335.
-
(2003)
Transplant Immunol.
, vol.11
, pp. 335
-
-
Hutchings, A.1
Wu, J.2
Asiedu, C.3
Hubbard, W.4
Eckhoff, D.5
Contreras, J.6
Thomas, F.T.7
Neville, D.8
Thomas, J.M.9
|