-
1
-
-
58149173418
-
What makes a fly enter diapause
-
Allen, M. J. (2007). What makes a fly enter diapause? Fly (Austin) 1, 307-310.
-
(2007)
Fly (Austin)
, vol.1
, pp. 307-310
-
-
Allen, M.J.1
-
2
-
-
0042626242
-
SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
-
An, J. H., and Blackwell, T. K. (2003). SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response. Genes Dev. 17,1882-1893.
-
(2003)
Genes Dev
, vol.17
, pp. 1882-1893
-
-
An, J.H.1
Blackwell, T.K.2
-
3
-
-
59149097747
-
Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases
-
Anderson, L. L. L., Mao, X., Scott, B. A., and Crowder, C. M. (2009). Survival from hypoxia in C. elegans by inactivation of aminoacyl-tRNA synthetases. Science 323, 630-633.
-
(2009)
Science
, vol.323
, pp. 630-633
-
-
Anderson, L.L.L.1
Mao, X.2
Scott, B.A.3
Crowder, C.M.4
-
4
-
-
72449170138
-
Starvation protects germline stem cells and extends reproductive longevity in C. elegans
-
Angelo, G., and Van Gilst, M. R. (2009). Starvation protects germline stem cells and extends reproductive longevity in C. elegans. Science 326, 954-958.
-
(2009)
Science
, vol.326
, pp. 954-958
-
-
Angelo, G.1
Van Gilst, M.R.2
-
5
-
-
84355161919
-
Chemical genetic screen for AMPKalpha2 substrates uncovers a network of proteins involved in mitosis
-
Banko, M. R., Allen, J. J., Schaffer, B. E., Wilker, E. W., Tsou, P., White, J. L., et al. (2011). Chemical genetic screen for AMPKalpha2 substrates uncovers a network of proteins involved in mitosis. Mol. Cell. 44, 878-892.
-
(2011)
Mol. Cell.
, vol.44
, pp. 878-892
-
-
Banko, M.R.1
Allen, J.J.2
Schaffer, B.E.3
Wilker, E.W.4
Tsou, P.5
White, J.L.6
-
6
-
-
33646024345
-
DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest
-
Baugh, L. R., and Sternberg, P. W (2006). DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest. Curr. Biol. 16, 780-785.
-
(2006)
Curr. Biol.
, vol.16
, pp. 780-785
-
-
Baugh, L.R.1
Sternberg, P.W.2
-
7
-
-
37549071066
-
5'-AMP-activated protein kinase signaling in Caenorhabditis elegans
-
Beale, E. G. (2008). 5'-AMP-activated protein kinase signaling in Caenorhabditis elegans. Exp. Biol. Med. 233, 12-20.
-
(2008)
Exp. Biol. Med.
, vol.233
, pp. 12-20
-
-
Beale, E.G.1
-
8
-
-
0038662783
-
Survival without brain damage after clinical death of 60-120 mins in dogs using suspended animation by profound hypothermia
-
Behringer, W., Safar, P., Wu, X., Kentner, R., Radovsky, A., Kochanek, P. M., et al. (2003). Survival without brain damage after clinical death of 60-120 mins in dogs using suspended animation by profound hypothermia. Crit. CareMed.31, 1523-1531.
-
(2003)
Crit. CareMed.
, vol.31
, pp. 1523-1531
-
-
Behringer, W.1
Safar, P.2
Wu, X.3
Kentner, R.4
Radovsky, A.5
Kochanek, P.M.6
-
9
-
-
70449578597
-
Environmental and physiological controls of blue crab avoidance behavior during exposure to hypoxia
-
Bell, G. W., Eggleston, D. B., and Noga, E. J. (2009). Environmental and physiological controls of blue crab avoidance behavior during exposure to hypoxia. Biol. Bull. 217, 161-172.
-
(2009)
Biol. Bull.
, vol.217
, pp. 161-172
-
-
Bell, G.W.1
Eggleston, D.B.2
Noga, E.J.3
-
10
-
-
35348972430
-
Genetic links between diet and lifespan: shared mechanisms from yeast to humans
-
Bishop, N. A., and Guarente, L. (2007). Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. Genet. 8, 835-844.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 835-844
-
-
Bishop, N.A.1
Guarente, L.2
-
11
-
-
34249891333
-
Two neurons mediate dietrestriction-induced longevity in C. elegans
-
Bishop, N. A., and Guarente, L. (2007). Two neurons mediate dietrestriction-induced longevity in C. elegans. Nature 447, 545-549.
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
12
-
-
34247093873
-
Suspended animation-like state protects mice from lethal hypoxia
-
Blackstone, E., and Roth, M. B. (2007). Suspended animation-like state protects mice from lethal hypoxia. Shock 27, 370-372.
-
(2007)
Shock
, vol.27
, pp. 370-372
-
-
Blackstone, E.1
Roth, M.B.2
-
13
-
-
20244390001
-
H2S induces a suspended animation-like state in mice
-
Blackstone, E., Morrison, M., and Roth, M. B. (2005). H2S induces a suspended animation-like state in mice. Science 308, 518.
-
(2005)
Science
, vol.308
, pp. 518
-
-
Blackstone, E.1
Morrison, M.2
Roth, M.B.3
-
14
-
-
0027751277
-
Interaction between temperature and hypoxia in the alligator
-
Branco, L. G., Pörtner, H. O., and Wood, S. C. (1993). Interaction between temperature and hypoxia in the alligator. Am. J. Physiol. 265, R1339-R1343.
-
(1993)
Am. J. Physiol.
, vol.265
-
-
Branco, L.G.1
Pörtner, H.O.2
Wood, S.C.3
-
15
-
-
75649150459
-
Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans
-
Budde, M. W., and Roth, M. B. (2010). Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans. Mol. Biol. Cell 21, 212-217.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 212-217
-
-
Budde, M.W.1
Roth, M.B.2
-
16
-
-
77954620098
-
Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice
-
Calvert, J. W., Elston, M., Nicholson, C. K., Gundewar, S., Jha, S., Elrod, J. W., et al. (2010). Genetic and pharmacologic hydrogen sulfide therapy attenuates ischemia-induced heart failure in mice. Circulation 122,11-19.
-
(2010)
Circulation
, vol.122
, pp. 11-19
-
-
Calvert, J.W.1
Elston, M.2
Nicholson, C.K.3
Gundewar, S.4
Jha, S.5
Elrod, J.W.6
-
17
-
-
70349233030
-
Hydrogen sulfide mediates cardioprotection through Nrf2 signaling
-
Calvert, J. W., Jha, S., Gundewar, S., Elrod, J. W., Ramachandran, A., Pattillo, C. B., et al. (2009). Hydrogen sulfide mediates cardioprotection through Nrf2 signaling. Circ. Res. 105, 365-374.
-
(2009)
Circ. Res.
, vol.105
, pp. 365-374
-
-
Calvert, J.W.1
Jha, S.2
Gundewar, S.3
Elrod, J.W.4
Ramachandran, A.5
Pattillo, C.B.6
-
18
-
-
0000733534
-
Organization for physiological homeostasis
-
Cannon, W.B. (1929). Organization for physiological homeostasis. Physiol. Rev. 9,399-431.
-
(1929)
Physiol. Rev.
, vol.9
, pp. 399-431
-
-
Cannon, W.B.1
-
19
-
-
79960490935
-
AMP-activated protein kinase: nature's energy sensor
-
Carling, D., Mayer, F. V., Sanders, M. J., and Gamblin, S. J. (2011). AMP-activated protein kinase: nature's energy sensor. Nat. Chem. Biol. 7, 512-518.
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 512-518
-
-
Carling, D.1
Mayer, F.V.2
Sanders, M.J.3
Gamblin, S.J.4
-
20
-
-
50049105823
-
The regulation of AMP-activated protein kinase by upstream kinases
-
Carling, D., Sanders, M. J., and Woods, A. (2008). The regulation of AMP-activated protein kinase by upstream kinases. Int. J. Obes. (Lond) 32(Suppl. 4),S55-S59.
-
(2008)
Int. J. Obes. (Lond)
, vol.32
, Issue.SUPPL. 4
-
-
Carling, D.1
Sanders, M.J.2
Woods, A.3
-
21
-
-
41649105073
-
Cell autonomy of HIF effects in Drosophila: tracheal cells sense hypoxia and induce terminal branch sprouting
-
Centanin, L., Dekanty, A., Romero, N., Irisarri, M., Gorr, T. A., and Wappner, P. (2008). Cell autonomy of HIF effects in Drosophila: tracheal cells sense hypoxia and induce terminal branch sprouting. Dev. Cell 14, 547-558.
-
(2008)
Dev. Cell
, vol.14
, pp. 547-558
-
-
Centanin, L.1
Dekanty, A.2
Romero, N.3
Irisarri, M.4
Gorr, T.A.5
Wappner, P.6
-
22
-
-
0014714807
-
Factors affecting the oxygen tension around cells growing in plastic Petri dishes
-
Chapman, J. D., Sturrock, J., Boag, J. W., and Crookall, J. O. (1970). Factors affecting the oxygen tension around cells growing in plastic Petri dishes. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 17,305-328.
-
(1970)
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.
, vol.17
, pp. 305-328
-
-
Chapman, J.D.1
Sturrock, J.2
Boag, J.W.3
Crookall, J.O.4
-
23
-
-
77954178837
-
Suspended animation extends survival limits of Caenorhabditis elegans and Saccharomyces cerevisiae at low temperature
-
Chan, K., Goldmark, J. P., and Roth, M. B. (2010). Suspended animation extends survival limits of Caenorhabditis elegans and Saccharomyces cerevisiae at low temperature. Mol. Biol. Cell 21, 2161-2171.
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 2161-2171
-
-
Chan, K.1
Goldmark, J.P.2
Roth, M.B.3
-
24
-
-
67149107430
-
HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans
-
doi:10.1371/journal.pgen.1000486
-
Chen, D., Thomas, E. L., and Kapahi, P. (2009). HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. PLoS Genet. 5, e1000486. doi: 10.1371/journal.pgen.1000486
-
(2009)
PLoS Genet
, vol.5
-
-
Chen, D.1
Thomas, E.L.2
Kapahi, P.3
-
25
-
-
4444303170
-
Facultative vivipary is a life-history trait in Caenorhabditis elegans
-
Chen, J., and Caswell-Chen, E. P. (2004). Facultative vivipary is a life-history trait in Caenorhabditis elegans. J. Nematol. 36, 107-113.
-
(2004)
J. Nematol.
, vol.36
, pp. 107-113
-
-
Chen, J.1
Caswell-Chen, E.P.2
-
26
-
-
0030830201
-
Embryos of Artemia franciscana survive four years of continuous anoxia: the case for complete metabolic rate depression
-
Clegg, J. (1997). Embryos of Artemia franciscana survive four years of continuous anoxia: the case for complete metabolic rate depression. J. Exp. Biol. 200,467-475.
-
(1997)
J. Exp. Biol.
, vol.200
, pp. 467-475
-
-
Clegg, J.1
-
27
-
-
0035983324
-
Loss of HIF-2alpha and inhibition of VEGF impair fet al lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
-
Compernolle, V., Brusselmans, K., Acker, T., Hoet, P., Tjwa, M., Beck, H., et al. (2002). Loss of HIF-2alpha and inhibition of VEGF impair fet al lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat. Med. 8, 702-710.
-
(2002)
Nat. Med.
, vol.8
, pp. 702-710
-
-
Compernolle, V.1
Brusselmans, K.2
Acker, T.3
Hoet, P.4
Tjwa, M.5
Beck, H.6
-
28
-
-
84861530634
-
Low O2 avoidance is associated with physiological perturbation but not exhaustion in the snapper (Pagrus auratus: Sparidae)
-
Cook, D. G., and Herbert, N. A. (2012). Low O2 avoidance is associated with physiological perturbation but not exhaustion in the snapper (Pagrus auratus: Sparidae). Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 162, 310-316.
-
(2012)
Comp. Biochem. Physiol. A. Mol. Integr. Physiol.
, vol.162
, pp. 310-316
-
-
Cook, D.G.1
Herbert, N.A.2
-
29
-
-
77950547646
-
The first metazoa living in permanently anoxic conditions
-
doi:10.1186/1741-7007-8-30
-
Danovaro, R., Dell'Anno, A., Pusceddu, A., Gambi, C., Heiner, I., and Kristensen, R. M. (2010). The first metazoa living in permanently anoxic conditions. BMC Biol. 8, 30. doi: 10.1186/1741-7007-8-30
-
(2010)
BMC Biol
, vol.8
, pp. 30
-
-
Danovaro, R.1
Dell'Anno, A.2
Pusceddu, A.3
Gambi, C.4
Heiner, I.5
Kristensen, R.M.6
-
30
-
-
0035910512
-
Hypoxia and nitric oxide induce a rapid, reversible cell cycle arrest of the Drosophila syncytial divisions
-
DiGregorio, P. J., Ubersax, J. A., and O'Farrell, P. H. (2001). Hypoxia and nitric oxide induce a rapid, reversible cell cycle arrest of the Drosophila syncytial divisions. J. Biol. Chem. 276, 1930-1937.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 1930-1937
-
-
DiGregorio, P.J.1
Ubersax, J.A.2
O'Farrell, P.H.3
-
31
-
-
0028214311
-
Cloning and characterization of LAG1, a longevity-assurance gene in yeast
-
D'Mello, N. P., Childress, A. M., Franklin, D. S., Kale, S. P., Pinswasdi, C., and Jazwinski, S. M. (1994). Cloning and characterization of LAG1, a longevity-assurance gene in yeast. J. Biol. Chem. 269, 15451-15459.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15451-15459
-
-
D'Mello, N.P.1
Childress, A.M.2
Franklin, D.S.3
Kale, S.P.4
Pinswasdi, C.5
Jazwinski, S.M.6
-
32
-
-
0032808433
-
Chemolithoheterotrophy in a metazoan tissue: sulfide supports cellular work in ciliated mussel gills
-
Doeller, J. E., Gaschen, B. K., Parrino, V., and Kraus, D. W (1999). Chemolithoheterotrophy in a metazoan tissue: sulfide supports cellular work in ciliated mussel gills. J. Exp. Biol. 202, 1953-1961.
-
(1999)
J. Exp. Biol.
, vol.202
, pp. 1953-1961
-
-
Doeller, J.E.1
Gaschen, B.K.2
Parrino, V.3
Kraus, D.W.4
-
33
-
-
4644266615
-
New roles for cysteine and transsulfuration enzymes: production of H2S, a neuromodulator and smooth muscle relaxant
-
Dominy, J. E., and Stipanuk, M. H. (2004). New roles for cysteine and transsulfuration enzymes: production of H2S, a neuromodulator and smooth muscle relaxant. Nutr. Rev. 62, 348-353.
-
(2004)
Nutr. Rev.
, vol.62
, pp. 348-353
-
-
Dominy, J.E.1
Stipanuk, M.H.2
-
34
-
-
0035378480
-
Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms.
-
Dong, Z., Venkatachalam, M. A., Wang, J., Patel, Y., Saikumar, P., Semenza, G. L., et al. (2001). Up-regulation of apoptosis inhibitory protein IAP-2 by hypoxia. Hif-1-independent mechanisms. J. Biol. Chem. 276, 18702-18709.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18702-18709
-
-
Dong, Z.1
Venkatachalam, M.A.2
Wang, J.3
Patel, Y.4
Saikumar, P.5
Semenza, G.L.6
-
35
-
-
77953257025
-
Aging and disease: connections to sirtuins
-
Donmez, G., and Guarente, L. (2010). Aging and disease: connections to sirtuins. Aging Cell 9, 285-290.
-
(2010)
Aging Cell
, vol.9
, pp. 285-290
-
-
Donmez, G.1
Guarente, L.2
-
36
-
-
0035041604
-
Cell cycle progression and cell division are sensitive to hypoxia in Drosophila melanogaster embryos
-
Douglas, R. M., Xu, T., and Haddad, G. G. (2001). Cell cycle progression and cell division are sensitive to hypoxia in Drosophila melanogaster embryos. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280, R1555-R1563.
-
(2001)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.280
-
-
Douglas, R.M.1
Xu, T.2
Haddad, G.G.3
-
37
-
-
4644308998
-
Hypoxia tolerance in mammalian heterotherms
-
Drew, K. L., Harris, M. B., LaManna, J. C., Smith, M. A., Zhu, X. W., and Ma, Y. L. (2004). Hypoxia tolerance in mammalian heterotherms. J. Exp. Biol. 207, 3155-3162.
-
(2004)
J. Exp. Biol.
, vol.207
, pp. 3155-3162
-
-
Drew, K.L.1
Harris, M.B.2
LaManna, J.C.3
Smith, M.A.4
Zhu, X.W.5
Ma, Y.L.6
-
38
-
-
0000710809
-
Appetitive response of the nematode Caenorhabditis elegans to oxygen
-
Dusenbery, D. B. (1980). Appetitive response of the nematode Caenorhabditis elegans to oxygen. J. Comp. Phys. 136, 333-336.
-
(1980)
J. Comp. Phys.
, vol.136
, pp. 333-336
-
-
Dusenbery, D.B.1
-
39
-
-
79955573042
-
Tissue oxygen tension monitoring: will it fill the void? Curr
-
Dyson, A., and Singer, M. (2011). Tissue oxygen tension monitoring: will it fill the void? Curr. Opin. Crit. Care 17, 281-289.
-
(2011)
Opin. Crit. Care
, vol.17
, pp. 281-289
-
-
Dyson, A.1
Singer, M.2
-
40
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein, A. C., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., et al. (2001). C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107, 43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O'Rourke, J.5
Mole, D.R.6
-
41
-
-
80051668850
-
The dual role of autophagy in cancer
-
Eskelinen, E.-L. (2011). The dual role of autophagy in cancer. Curr. Opin. Pharmacol. 11, 294-300.
-
(2011)
Curr. Opin. Pharmacol.
, vol.11
, pp. 294-300
-
-
Eskelinen, E.-L.1
-
42
-
-
84867606574
-
Creating defined gaseous environments to study the effects of hypoxia on C. elegans
-
Fawcett, E. M., Horsman, J. W., and Miller, D. L. (2012). Creating defined gaseous environments to study the effects of hypoxia on C. elegans. J. Vis. Exp. 65, 34088.
-
(2012)
J. Vis. Exp.
, vol.65
, pp. 34088
-
-
Fawcett, E.M.1
Horsman, J.W.2
Miller, D.L.3
-
43
-
-
50049116926
-
C. elegans dauer formation and the molecular basis of plasticity
-
Fielenbach, N., and Antebi, A. (2008). C. elegans dauer formation and the molecular basis of plasticity. Genes Dev. 22,2149-2165.
-
(2008)
Genes Dev
, vol.22
, pp. 2149-2165
-
-
Fielenbach, N.1
Antebi, A.2
-
44
-
-
79958847747
-
Basis for the use of localized hypothermia during radical pelvic surgery
-
Finley, D. S. (2011). Basis for the use of localized hypothermia during radical pelvic surgery. Nat. Rev. Urol. 8, 345-350.
-
(2011)
Nat. Rev. Urol.
, vol.8
, pp. 345-350
-
-
Finley, D.S.1
-
45
-
-
0021952110
-
Reversible chromosome condensation induced in Drosophila embryos by anoxia: visualization of interphase nuclear organization
-
Foe, V E., and Alberts, B. M. (1985). Reversible chromosome condensation induced in Drosophila embryos by anoxia: visualization of interphase nuclear organization.J. Cell Biol. 100, 1623-1636.
-
(1985)
J. Cell Biol.
, vol.100
, pp. 1623-1636
-
-
Foe, V.E.1
Alberts, B.M.2
-
46
-
-
77951176737
-
Extending healthy life span - from yeast to humans
-
Fontana, L., Partridge, L., and Longo, V D. (2010). Extending healthy life span - from yeast to humans. Science 328,321-326.
-
(2010)
Science
, vol.328
, pp. 321-326
-
-
Fontana, L.1
Partridge, L.2
Longo, V.D.3
-
47
-
-
67349119501
-
Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments
-
Frazier, H. N. III, and Roth, M. B. (2009). Adaptive sugar provisioning controls survival of C. elegans embryos in adverse environments. Curr. Biol. 19,859-863.
-
(2009)
Curr. Biol.
, vol.19
, pp. 859-863
-
-
Frazier III, H.N.1
Roth, M.B.2
-
48
-
-
84857409875
-
Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production
-
Fu, M., Zhang, W., Wu, L., Yang, G., Li, H., and Wang, R. (2012). Hydrogen sulfide (H2S) metabolism in mitochondria and its regulatory role in energy production. Proc. Natl. Acad. Sci. U.S.A. 109,2943-2948.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 2943-2948
-
-
Fu, M.1
Zhang, W.2
Wu, L.3
Yang, G.4
Li, H.5
Wang, R.6
-
49
-
-
33646063579
-
C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline
-
Fukuyama, M., Rougvie, A. E., and Rothman, J. H. (2006). C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline. Curr. Biol. 16,773-779.
-
(2006)
Curr. Biol.
, vol.16
, pp. 773-779
-
-
Fukuyama, M.1
Rougvie, A.E.2
Rothman, J.H.3
-
50
-
-
84863533791
-
The stress of protein misfolding: from single cells to multicellular organisms
-
doi:10.1101/cshperspect.a009704
-
Gidalevitz, T., Prahlad, V., and Morimoto, R. I. (2011). The stress of protein misfolding: from single cells to multicellular organisms. Cold Spring Harb. Perspect. Biol. 3. doi: 10.1101/cshperspect.a009704
-
(2011)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Gidalevitz, T.1
Prahlad, V.2
Morimoto, R.I.3
-
51
-
-
33646016261
-
Sensing and responding to hypoxia via HIF in model invertebrates
-
Gorr, T. A., Gassmann, M., and Wappner, P. (2006). Sensing and responding to hypoxia via HIF in model invertebrates. J. Insect Physiol. 52, 349-364.
-
(2006)
J. Insect Physiol.
, vol.52
, pp. 349-364
-
-
Gorr, T.A.1
Gassmann, M.2
Wappner, P.3
-
52
-
-
3142674291
-
Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue
-
Gray, J. M., Karow, D. S., Lu, H., Chang, A. J., Chang, J. S., Ellis, R. E., et al. (2004). Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature 430, 317-322.
-
(2004)
Nature
, vol.430
, pp. 317-322
-
-
Gray, J.M.1
Karow, D.S.2
Lu, H.3
Chang, A.J.4
Chang, J.S.5
Ellis, R.E.6
-
53
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C.elegans
-
Greer, E. L., and Brunet, A. (2009). Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C.elegans. Aging Cell 8, 113-127.
-
(2009)
Aging Cell
, vol.8
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
54
-
-
49749104841
-
Diapause in tardigrades: a study of factors involved in encystment
-
Guidetti, R., Boschini, D., Altiero, T., Bertolani, R., and Rebecchi, L. (2008). Diapause in tardigrades: a study of factors involved in encystment. J. Exp. Biol. 211, 2296-2302.
-
(2008)
J. Exp. Biol.
, vol.211
, pp. 2296-2302
-
-
Guidetti, R.1
Boschini, D.2
Altiero, T.3
Bertolani, R.4
Rebecchi, L.5
-
55
-
-
78649350746
-
The aging stress response
-
Haigis, M. C., and Yankner, B. A. (2010). The aging stress response. Mol. Cell 40,333-344.
-
(2010)
Mol. Cell
, vol.40
, pp. 333-344
-
-
Haigis, M.C.1
Yankner, B.A.2
-
56
-
-
29944435594
-
Characterization of sub-nuclear changes in Caenorhabditis elegans embryos exposed to brief, intermediate and long-term anoxia to analyze anoxia-induced cell cycle arrest
-
doi:10.1186/1471-2121-6-47
-
Hajeri, V. A., Trejo, J., and Padilla, P. A. (2005). Characterization of sub-nuclear changes in Caenorhabditis elegans embryos exposed to brief, intermediate and long-term anoxia to analyze anoxia-induced cell cycle arrest. BMC Cell Biol. 6, 47. doi: 10.1186/1471-2121-6-47
-
(2005)
BMC Cell Biol
, vol.6
, pp. 47
-
-
Hajeri, V.A.1
Trejo, J.2
Padilla, P.A.3
-
57
-
-
22344443522
-
A systematic RNAi screen for longevity genes in C. elegans
-
Hamilton, B., Dong, Y., Shindo, M., Liu, W., Odell, I., Ruvkun, G., et al. (2005). A systematic RNAi screen for longevity genes in C. elegans. Genes Dev. 19, 1544-1555.
-
(2005)
Genes Dev
, vol.19
, pp. 1544-1555
-
-
Hamilton, B.1
Dong, Y.2
Shindo, M.3
Liu, W.4
Odell, I.5
Ruvkun, G.6
-
58
-
-
79957533816
-
Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals
-
Hand, S. C., Menze, M. A., Borcar, A., Patil, Y., Covi, J. A., Reynolds, J. A., et al. (2011). Metabolic restructuring during energy-limited states: insights from Artemia franciscana embryos and other animals. J. Insect Physiol. 57, 584-594.
-
(2011)
J. Insect Physiol.
, vol.57
, pp. 584-594
-
-
Hand, S.C.1
Menze, M.A.2
Borcar, A.3
Patil, Y.4
Covi, J.A.5
Reynolds, J.A.6
-
59
-
-
40149105890
-
A role for autophagy in the extension of lifespan by dietary restriction in C. elegans
-
doi:10.1371/journal.pgen.0040024
-
Hansen, M., Chandra, A., Mitic, L. L., Onken, B., Driscoll, M., and Kenyon, C. (2008). A role for autophagy in the extension of lifespan by dietary restriction in C. elegans. PLoS Genet. 4, e24. doi: 10.1371/journal.pgen.0040024
-
(2008)
PLoS Genet
, vol.4
-
-
Hansen, M.1
Chandra, A.2
Mitic, L.L.3
Onken, B.4
Driscoll, M.5
Kenyon, C.6
-
60
-
-
33645472504
-
New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen
-
doi:10.1371/journal.pgen.0010017
-
Hansen, M., Hsu, A. L., Dillin, A., and Kenyon, C. (2005). New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. PLoS Genet. 1, e17. doi: 10.1371/journal.pgen.0010017
-
(2005)
PLoS Genet
, vol.1
-
-
Hansen, M.1
Hsu, A.L.2
Dillin, A.3
Kenyon, C.4
-
61
-
-
33846423520
-
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
-
Hansen, M., Taubert, S., Crawford, D., Libina, N., Lee, S. J., and Kenyon, C. (2007). Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6, 95-110.
-
(2007)
Aging Cell
, vol.6
, pp. 95-110
-
-
Hansen, M.1
Taubert, S.2
Crawford, D.3
Libina, N.4
Lee, S.J.5
Kenyon, C.6
-
62
-
-
80053035284
-
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
-
Hardie, D. G. (2011). AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev. 25,1895-1908.
-
(2011)
Genes Dev
, vol.25
, pp. 1895-1908
-
-
Hardie, D.G.1
-
63
-
-
79951772967
-
Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism
-
Hardie, D. G. (2011). Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism. Proc. Nutr. Soc. 70, 92-99.
-
(2011)
Proc. Nutr. Soc.
, vol.70
, pp. 92-99
-
-
Hardie, D.G.1
-
64
-
-
0038199737
-
Management of cellular energy by the AMP-activatedprotein kinase system
-
Hardie, D. G., Scott, J. W., Pan, D. A., and Hudson, E. R. (2003) Management of cellular energy by the AMP-activatedprotein kinase system. FEBSLett. 546, 113-120.
-
(2003)
FEBSLett
, vol.546
, pp. 113-120
-
-
Hardie, D.G.1
Scott, J.W.2
Pan, D.A.3
Hudson, E.R.4
-
65
-
-
79960652801
-
Molecular chaperones in protein folding and proteostasis
-
Hartl, F. U., Bracher, A., and Hayer-Hartl, M. (2011). Molecular chaperones in protein folding and proteostasis. Nature 475, 324-332.
-
(2011)
Nature
, vol.475
, pp. 324-332
-
-
Hartl, F.U.1
Bracher, A.2
Hayer-Hartl, M.3
-
66
-
-
0029796904
-
Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
-
Hochachka, P. W., Buck, L. T., Doll, C. J., and Land, S. C. (1996). Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc. Natl. Acad. Sci. U.S.A. 93, 9493-9498.
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9493-9498
-
-
Hochachka, P.W.1
Buck, L.T.2
Doll, C.J.3
Land, S.C.4
-
67
-
-
0027467912
-
Oxygen-dependent perturbation of life span and aging rate in the nematode
-
Honda, S., Ishii, N., Suzuki, K., and Matsuo, M. (1993). Oxygen-dependent perturbation of life span and aging rate in the nematode. J. Gerontol. 48, B57-B61.
-
(1993)
J. Gerontol.
, vol.48
-
-
Honda, S.1
Ishii, N.2
Suzuki, K.3
Matsuo, M.4
-
68
-
-
0032782364
-
The daf-2 gene network for longevity regulates oxi dative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
-
Honda, Y., and Honda, S. (1999). The daf-2 gene network for longevity regulates oxi dative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEBJ. 13,1385-1393.
-
(1999)
FASEBJ
, vol.13
, pp. 1385-1393
-
-
Honda, Y.1
Honda, S.2
-
69
-
-
22144488142
-
Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans
-
Houthoofd, K., Fidalgo, M. A., Hoogewijs, D., Braeckman, B. P., Lenaerts, I., Brys, K., et al. (2005). Metabolism, physiology and stress defense in three aging Ins/IGF-1 mutants of the nematode Caenorhabditis elegans. Aging Cell 4, 87-95.
-
(2005)
Aging Cell
, vol.4
, pp. 87-95
-
-
Houthoofd, K.1
Fidalgo, M.A.2
Hoogewijs, D.3
Braeckman, B.P.4
Lenaerts, I.5
Brys, K.6
-
70
-
-
38449105152
-
Dauer
-
Hu, P. J. (2007). Dauer. WormBook, 1-19.
-
(2007)
WormBook
, pp. 1-19
-
-
Hu, P.J.1
-
71
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1alpha
-
Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., et al. (1998). Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1alpha. Genes Dev. 12, 149-162.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
-
72
-
-
58849160520
-
Ceramide and neurode-generation: susceptibility of neurons and oligodendrocytes to cell damage and death
-
Jana, A., Hogan, E. L., and Pahan, K. (2009). Ceramide and neurode-generation: susceptibility of neurons and oligodendrocytes to cell damage and death. J. Neurol. Sci. 278, 5-15.
-
(2009)
J. Neurol. Sci.
, vol.278
, pp. 5-15
-
-
Jana, A.1
Hogan, E.L.2
Pahan, K.3
-
73
-
-
77950828364
-
Molecular mechanism for H(2)S-induced activation of K(ATP) channels
-
Jiang, B., Tang, G., Cao, K., Wu, L., and Wang, R. (2010). Molecular mechanism for H(2)S-induced activation of K(ATP) channels. Antioxid. Redox Signal. 15,1167-1178.
-
(2010)
Antioxid. Redox Signal.
, vol.15
, pp. 1167-1178
-
-
Jiang, B.1
Tang, G.2
Cao, K.3
Wu, L.4
Wang, R.5
-
74
-
-
0034940761
-
The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia
-
Jiang, H., Guo, R., and Powell-Coffman, J. A. (2001). The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia. Proc. Natl. Acad. Sci. U.S.A. 98, 7916-7921.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 7916-7921
-
-
Jiang, H.1
Guo, R.2
Powell-Coffman, J.A.3
-
75
-
-
80053641483
-
Increased transsulfuration mediates longevity and dietary restriction in Drosophila
-
Kabil, H., Kabil, O., Banerjee, R., Harshman, L. G., and Pletcher, S. D. (2011). Increased transsulfuration mediates longevity and dietary restriction in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 108, 16831-16836.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 16831-16836
-
-
Kabil, H.1
Kabil, O.2
Banerjee, R.3
Harshman, L.G.4
Pletcher, S.D.5
-
76
-
-
54549113030
-
The von Hippel-Lindau tumour supressor protein: O2 sensing and cancer
-
Kaelin, W. G. (2008). The von Hippel-Lindau tumour supressor protein: O2 sensing and cancer. Nat. Rev. Cancer 8, 865-873.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 865-873
-
-
Kaelin, W.G.1
-
77
-
-
0037088576
-
Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity
-
Katschinski, D. M., Le, L., Heinrich, D., Wagner, K. F., Hofer, T., Schindler, S. G., et al. (2002). Heat induction of the unphosphorylated form of hypoxia-inducible factor-1alpha is dependent on heat shock protein-90 activity. J. Biol. Chem. 277, 9262-9267.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9262-9267
-
-
Katschinski, D.M.1
Le, L.2
Heinrich, D.3
Wagner, K.F.4
Hofer, T.5
Schindler, S.G.6
-
78
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith, B., and Simon, M. C. (2007). Hypoxia-inducible factors, stem cells, and cancer. Cell 129,465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
79
-
-
0027771804
-
A C. elegans mutant that lives twice as long as wild type
-
Kenyon, C., Chang, J., Gensch, E., Rudner, A., and Tabtiang, R. (1993). A C. elegans mutant that lives twice as long as wild type. Nature 366,461-464.
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
Chang, J.2
Gensch, E.3
Rudner, A.4
Tabtiang, R.5
-
80
-
-
16644373473
-
Role of VHL gene mutation in human cancer
-
Kim, W Y, and Kaelin, W. G. (2004). Role of VHL gene mutation in human cancer.J. Clin. Oncol. 22, 4991-5004.
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 4991-5004
-
-
Kim, W.Y.1
Kaelin, W.G.2
-
81
-
-
78651457395
-
Hydrogen sulfide: its production, release and functions
-
Kimura, H. (2011). Hydrogen sulfide: its production, release and functions. Amino Acids 41,113-121.
-
(2011)
Amino Acids
, vol.41
, pp. 113-121
-
-
Kimura, H.1
-
82
-
-
80051940012
-
Cyto-protective actions of hydrogen sulfide in ischaemia-reperfusion injury
-
King, A. L., and Lefer, D. J. (2011). Cyto-protective actions of hydrogen sulfide in ischaemia-reperfusion injury. Exp. Physiol. 96, 840-846.
-
(2011)
Exp. Physiol.
, vol.96
, pp. 840-846
-
-
King, A.L.1
Lefer, D.J.2
-
83
-
-
0037312020
-
How does calorie restriction work?
-
Koubova, J., and Guarente, L. (2003). How does calorie restriction work? Genes Dev. 17,313-321.
-
(2003)
Genes Dev
, vol.17
, pp. 313-321
-
-
Koubova, J.1
Guarente, L.2
-
84
-
-
33745840203
-
5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments
-
Laderoute, K. R., Amin, K., Calaoagan, J. M., Knapp, M., Le, T., Orduna, J., et al. (2006). 5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments. Mol. Cell. Biol. 26, 5336-5347.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 5336-5347
-
-
Laderoute, K.R.1
Amin, K.2
Calaoagan, J.M.3
Knapp, M.4
Le, T.5
Orduna, J.6
-
85
-
-
84869488061
-
Lessons from C. elegans: signaling pathways for longevity
-
doi:10.1016/j.tem.2012.07.007 [Epub ahead of print]
-
Lapierre, L. R., and Hansen, M. (2012). Lessons from C. elegans: signaling pathways for longevity. Trends Endocrinol. Metab. doi: 10.1016/j.tem.2012.07.007 [Epub ahead of print].
-
(2012)
Trends Endocrinol. Metab.
-
-
Lapierre, L.R.1
Hansen, M.2
-
86
-
-
79751481650
-
Environmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegans
-
doi:10.1371/journal. pone.0016790
-
LaRue, B. L., and Padilla, P. A. (2011). Environmental and genetic preconditioning for long-term anoxia responses requires AMPK in Caenorhabditis elegans. PLoS ONE 6, e16790. doi: 10.1371/journal. pone.0016790
-
(2011)
PLoS ONE
, vol.6
-
-
LaRue, B.L.1
Padilla, P.A.2
-
87
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
Lee, C., Raffaghello, L., Brandhorst, S., Safdie, E M., Bianchi, G., Martin-Montalvo, A., et al. (2012). Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci. Transl. Med. 4, 124ra27.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
Safdie, E.M.4
Bianchi, G.5
Martin-Montalvo, A.6
-
88
-
-
57349122102
-
An RNA interference screen identifies a novel regulator of target of rapamycin that mediates hypoxia suppression of translation in DrosophilaS2 cells
-
Lee, S.-J., Feldman, R., and O'Farrell, P. H. (2008). An RNA interference screen identifies a novel regulator of target of rapamycin that mediates hypoxia suppression of translation in DrosophilaS2 cells. Mol. Biol. Cell 19, 4051-4061.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4051-4061
-
-
Lee, S.-J.1
Feldman, R.2
O'Farrell, P.H.3
-
89
-
-
0037466652
-
DAF-16 target genes that control C. elegans life-span and metabolism
-
Lee, S. S., Kennedy, S., Tolonen, A. C., and Ruvkun, G. (2003). DAF-16 target genes that control C. elegans life-span and metabolism. Science 300, 644-647
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
90
-
-
79952582588
-
HIF-1 modulates longevity and healthspan in a temperature-dependent manner
-
Leiser, S. F., Begun, A., and Kaeberlein, M. (2011). HIF-1 modulates longevity and healthspan in a temperature-dependent manner. Aging Cell 10,318-326.
-
(2011)
Aging Cell
, vol.10
, pp. 318-326
-
-
Leiser, S.F.1
Begun, A.2
Kaeberlein, M.3
-
91
-
-
79959823394
-
Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity
-
doi:10.1371/journal.pgen.1002119
-
Li, X., Matilainen, O., Jin, C., Glover-Cutter, K. M., Holmberg, C. I., and Blackwell, T. K. (2011). Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS Genet. 7, e1002119. doi: 10.1371/journal.pgen.1002119
-
(2011)
PLoS Genet
, vol.7
-
-
Li, X.1
Matilainen, O.2
Jin, C.3
Glover-Cutter, K.M.4
Holmberg, C.I.5
Blackwell, T.K.6
-
92
-
-
79958021506
-
Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels
-
Liang, G. H., Adebiyi, A., Leo, M. D., McNally, E. M., Leffler, C. W., and Jaggar, J. H. (2011). Hydrogen sulfide dilates cerebral arterioles by activating smooth muscle cell plasma membrane KATP channels. Am. J. Physiol. Heart Circ. Physiol. 300, H2088-H2095.
-
(2011)
Am. J. Physiol. Heart Circ. Physiol.
, vol.300
-
-
Liang, G.H.1
Adebiyi, A.2
Leo, M.D.3
McNally, E.M.4
Leffler, C.W.5
Jaggar, J.H.6
-
93
-
-
77955499804
-
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha
-
Lim, J.-H., Lee, Y.-M., Chun, Y.-S., Chen, J., Kim, J.-E., and Park, J.-W. (2010). Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. Mol. Cell 38, 864-878.
-
(2010)
Mol. Cell
, vol.38
, pp. 864-878
-
-
Lim, J.-H.1
Lee, Y.-M.2
Chun, Y.-S.3
Chen, J.4
Kim, J.-E.5
Park, J.-W.6
-
94
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton, P. (1999). Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568.
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
95
-
-
0029123058
-
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
-
Lithgow, G. J., White, T. M., Melov, S., and Johnson, T. E. (1995). Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. U.S.A. 92,7540-7544.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7540-7544
-
-
Lithgow, G.J.1
White, T.M.2
Melov, S.3
Johnson, T.E.4
-
96
-
-
32444433450
-
Hypoxia-induced energy stress regulates mRNA translation and cell growth
-
Liu, L., Cash, T. P., Jones, R. G., Keith, B., Thompson, C. B., and Simon, M. C. (2006). Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol. Cell 21, 521-531.
-
(2006)
Mol. Cell
, vol.21
, pp. 521-531
-
-
Liu, L.1
Cash, T.P.2
Jones, R.G.3
Keith, B.4
Thompson, C.B.5
Simon, M.C.6
-
97
-
-
77957568899
-
Hypoxia-inducible factor- 1alpha is involved in the proangiogenic effect of hydrogen sulfide under hypoxic stress
-
Liu, X., Pan, L., Zhuo, Y., Gong, Q., Rose, P., and Zhu,Y. (2010). Hypoxia-inducible factor- 1alpha is involved in the pro-angiogenic effect of hydrogen sulfide under hypoxic stress. Biol. Pharm. Bull. 33, 1550-1554.
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 1550-1554
-
-
Liu, X.1
Pan, L.2
Zhuo, Y.3
Gong, Q.4
Rose, P.5
Zhu, Y.6
-
98
-
-
57349140895
-
Linking sirtuins, IGF-I signaling, and starvation
-
Longo, V. D. (2009). Linking sirtuins, IGF-I signaling, and starvation. Exp. Gerontol. 44, 70-74.
-
(2009)
Exp. Gerontol.
, vol.44
, pp. 70-74
-
-
Longo, V.D.1
-
99
-
-
11144301980
-
Embryonic diapause and its regulation
-
Lopes, E L., Desmarais, J. A., and Murphy, B. D. (2004). Embryonic diapause and its regulation. Reproduction 128, 669-678.
-
(2004)
Reproduction
, vol.128
, pp. 669-678
-
-
Lopes, E.L.1
Desmarais, J.A.2
Murphy, B.D.3
-
100
-
-
84858056556
-
2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans
-
2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans. Neuron 73, 925-940.
-
(2012)
Neuron
, vol.73
, pp. 925-940
-
-
Ma, D.K.1
Vozdek, R.2
Bhatla, N.3
Horvitz, H.R.4
-
101
-
-
62449091135
-
Systematic identification of gene activities promoting hypoxic death
-
Mabon, M. E., Mao, X., Jiao, Y., Scott, B. A., and Crowder, C. M. (2009). Systematic identification of gene activities promoting hypoxic death. Genetics 181,483-496.
-
(2009)
Genetics
, vol.181
, pp. 483-496
-
-
Mabon, M.E.1
Mao, X.2
Jiao, Y.3
Scott, B.A.4
Crowder, C.M.5
-
102
-
-
70949092200
-
Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway
-
doi:10.1371/journal.pone.0007937
-
Mabon, M. E., Scott, B. A., and Crowder, C. M. (2009). Divergent mechanisms controlling hypoxic sensitivity and lifespan by the DAF-2/insulin/IGF-receptor pathway. PLoS ONE 4, e7937. doi: 10.1371/journal.pone.0007937
-
(2009)
PLoS ONE
, vol.4
-
-
Mabon, M.E.1
Scott, B.A.2
Crowder, C.M.3
-
103
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
Majmundar, A. J., Wong, W. J., and Simon, M. C. (2010). Hypoxia-inducible factors and the response to hypoxic stress. Mol. Cell 40,294-309.
-
(2010)
Mol. Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
104
-
-
79953233802
-
Re-evaluating the general(ized) roles of AMPK in cellular metabolism
-
Mantovani, J., and Roy, R. (2011). Re-evaluating the general(ized) roles of AMPK in cellular metabolism. FEBS Lett. 585, 967-972.
-
(2011)
FEBS Lett
, vol.585
, pp. 967-972
-
-
Mantovani, J.1
Roy, R.2
-
105
-
-
77957826835
-
Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery
-
Mao, X. R., and Crowder, C. M. (2010). Protein misfolding induces hypoxic preconditioning via a subset of the unfolded protein response machinery. Mol. Cell. Biol. 30, 5033-5042.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5033-5042
-
-
Mao, X.R.1
Crowder, C.M.2
-
106
-
-
66349098677
-
Proteasomal regulation of the hypoxic response modulates aging in C. elegans
-
Mehta, R., Steinkraus, K. A., Sutphin, G. L., Ramos, F. J., Shamieh, L. S., Huh, A., et al. (2009). Proteasomal regulation of the hypoxic response modulates aging in C. elegans. Science 324,1196-1198.
-
(2009)
Science
, vol.324
, pp. 1196-1198
-
-
Mehta, R.1
Steinkraus, K.A.2
Sutphin, G.L.3
Ramos, F.J.4
Shamieh, L.S.5
Huh, A.6
-
107
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
Meléndez, A., Tallóczy, Z., Seaman, M., Eskelinen, E.-L., Hall, D. H., and Levine, B. (2003). Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Meléndez, A.1
Tallóczy, Z.2
Seaman, M.3
Eskelinen, E.-L.4
Hall, D.H.5
Levine, B.6
-
108
-
-
33751350245
-
Glyceraldehyde-3-phosphate dehydrogenase mediates anoxia response and survival in Caenorhabditis elegans
-
Mendenhall, A. R., LaRue, B., and Padilla, P. A. (2006). Glyceraldehyde-3-phosphate dehydrogenase mediates anoxia response and survival in Caenorhabditis elegans. Genetics 174, 1173-1187.
-
(2006)
Genetics
, vol.174
, pp. 1173-1187
-
-
Mendenhall, A.R.1
LaRue, B.2
Padilla, P.A.3
-
109
-
-
65249102170
-
Protection of C. elegans from anoxia by HYL-2 ceramide synthase
-
Menuz, V., Howell, K. S., Gentina, S., Epstein, S., Riezman, I., Fornallaz-Mulhauser, M., et al. (2009). Protection of C. elegans from anoxia by HYL-2 ceramide synthase. Science 324,381-384.
-
(2009)
Science
, vol.324
, pp. 381-384
-
-
Menuz, V.1
Howell, K.S.2
Gentina, S.3
Epstein, S.4
Riezman, I.5
Fornallaz-Mulhauser, M.6
-
110
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagyand metabolism
-
Mihaylova, M. M., and Shaw, R. J. (2011). The AMPK signalling pathway coordinates cell growth, autophagyand metabolism. Nat. Cell Biol. 13, 1016-1023.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
111
-
-
38049180882
-
Hydrogen sulfide increases thermo-tolerance and lifespan in Caenorhabditis elegans
-
Miller, D. L., and Roth, M. B. (2007). Hydrogen sulfide increases thermo-tolerance and lifespan in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 104,20618-20622.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20618-20622
-
-
Miller, D.L.1
Roth, M.B.2
-
112
-
-
67650963694
-
C. elegans are protected from lethal hypoxia by an embryonic diapause
-
Miller, D. L., and Roth, M. B. (2009). C. elegans are protected from lethal hypoxia by an embryonic diapause. Curr. Biol. 19, 1233-1237.
-
(2009)
Curr. Biol.
, vol.19
, pp. 1233-1237
-
-
Miller, D.L.1
Roth, M.B.2
-
113
-
-
80053338536
-
HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans
-
doi:10.1371/journal.pone.0025476
-
Miller, D. L., Budde, M. W., and Roth, M.B. (2011). HIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans. PLoS ONE 6, e25476. doi: 10.1371/journal.pone.0025476
-
(2011)
PLoS ONE
, vol.6
-
-
Miller, D.L.1
Budde, M.W.2
Roth, M.B.3
-
114
-
-
76249106732
-
Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice
-
Mitchell, J. R., Verweij, M., Brand, K., van de Ven, M., Goemaere, N., van den Engel, S., et al. (2010). Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice. Aging Cell 9, 40-53.
-
(2010)
Aging Cell
, vol.9
, pp. 40-53
-
-
Mitchell, J.R.1
Verweij, M.2
Brand, K.3
van de Ven, M.4
Goemaere, N.5
van den Engel, S.6
-
115
-
-
33746650587
-
Effects of caloric restriction are species-specific
-
Mockett, R. J., Cooper, T. M., Orr, W. C., and Sohal, R. S. (2006). Effects of caloric restriction are species-specific. Biogerontology 7, 157-160.
-
(2006)
Biogerontology
, vol.7
, pp. 157-160
-
-
Mockett, R.J.1
Cooper, T.M.2
Orr, W.C.3
Sohal, R.S.4
-
116
-
-
78651027469
-
George E. Brown Memorial Lecture: oxygen tension of tissues
-
Montgomery, H. (1957). George E. Brown Memorial Lecture: oxygen tension of tissues in vivo. Circulation 15,646-660.
-
(1957)
in vivo. Circulation
, vol.15
, pp. 646-660
-
-
Montgomery, H.1
-
117
-
-
80052317552
-
Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels
-
Mungai, P. T., Waypa, G. B., Jairaman, A., Prakriya, M., Dokic, D., Ball, M. K., et al. (2011). Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Mol. Cell. Biol. 31, 3531-3545.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 3531-3545
-
-
Mungai, P.T.1
Waypa, G.B.2
Jairaman, A.3
Prakriya, M.4
Dokic, D.5
Ball, M.K.6
-
118
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy, C. T., McCarroll, S. A., Bargmann, C. I., Fraser, A., Kamath, R.S.,Ahringer,J., et al. (2003). Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424,277-283.
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
-
119
-
-
66449084646
-
Signaling by gasotransmitters
-
Mustafa, A. K., Gadalla, M. M., and Snyder, S. H. (2009). Signaling by gasotransmitters. Sci. Signal. 2, re2.
-
(2009)
Sci. Signal.
, vol.2
-
-
Mustafa, A.K.1
Gadalla, M.M.2
Snyder, S.H.3
-
120
-
-
33645090940
-
Inhibition of germline proliferation during C. elegans dauer development requires PTEN
-
Narbonne, P., and Roy, R. (2006). Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling. Development 133, 611-619.
-
(2006)
LKB1 and AMPK signalling. Development
, vol.133
, pp. 611-619
-
-
Narbonne, P.1
Roy, R.2
-
121
-
-
79251604405
-
Hypoxia-inducible factor-1 (HIF-1)-independent microvascular angio-genesis in the aged rat brain
-
Ndubuizu, O. I., Tsipis, C. P., Li, A., and LaManna, J. C. (2010). Hypoxia-inducible factor-1 (HIF-1)-independent microvascular angio-genesis in the aged rat brain. Brain Res. 1366,101-109.
-
(2010)
Brain Res
, vol.1366
, pp. 101-109
-
-
Ndubuizu, O.I.1
Tsipis, C.P.2
Li, A.3
LaManna, J.C.4
-
122
-
-
77955269222
-
Hydrogen sulfide and ischemia-reperfusion injury
-
Nicholson, C. K., and Calvert, J. W. (2010). Hydrogen sulfide and ischemia-reperfusion injury. Pharmacol. Res. 62, 289-297.
-
(2010)
Pharmacol. Res.
, vol.62
, pp. 289-297
-
-
Nicholson, C.K.1
Calvert, J.W.2
-
123
-
-
2942643921
-
Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans
-
Nystul, T. G., and Roth, M. B. (2004). Carbon monoxide-induced suspended animation protects against hypoxic damage in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 101,9133-9136.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 9133-9136
-
-
Nystul, T.G.1
Roth, M.B.2
-
124
-
-
0242494080
-
Suspended animation in C. elegans requires the spindle checkpoint
-
Nystul, T. G., Goldmark, J. P., Padilla, P. A., and Roth, M. B. (2003). Suspended animation in C. elegans requires the spindle checkpoint. Science 302,1038-1041.
-
(2003)
Science
, vol.302
, pp. 1038-1041
-
-
Nystul, T.G.1
Goldmark, J.P.2
Padilla, P.A.3
Roth, M.B.4
-
125
-
-
0035107440
-
Conserved responses to oxygen deprivation
-
O'Farrell, P. H. (2001). Conserved responses to oxygen deprivation. J. Clin. Invest. 107,671-674.
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 671-674
-
-
O'Farrell, P.H.1
-
126
-
-
70350625466
-
Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf
-
Oliveira, R. P., Porter Abate, J., Dilks, K., Landis, J., Ashraf, J., Murphy, C. T., et al. (2009). Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging Cell 8, 524-541.
-
(2009)
Aging Cell
, vol.8
, pp. 524-541
-
-
Oliveira, R.P.1
Porter Abate, J.2
Dilks, K.3
Landis, J.4
Ashraf, J.5
Murphy, C.T.6
-
127
-
-
84866684700
-
Mitochondrial adaptations to utilize hydrogen sul-fide for energy and signaling
-
Olson, K. R. (2012). Mitochondrial adaptations to utilize hydrogen sul-fide for energy and signaling.J. Comp. Physiol. B. 182,881-897.
-
(2012)
J. Comp. Physiol. B.
, vol.182
, pp. 881-897
-
-
Olson, K.R.1
-
128
-
-
0035912835
-
Oxygen deprivation causes suspended animation in the zebrafish embryo
-
Padilla, P. A., and Roth, M. B. (2001). Oxygen deprivation causes suspended animation in the zebrafish embryo. Proc. Natl. Acad. Sci. U.S.A. 98,7331-7335.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7331-7335
-
-
Padilla, P.A.1
Roth, M.B.2
-
129
-
-
0035999972
-
Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans
-
Padilla, P. A., Nystul, T. G., Zager, R. A., Johnson, A. C. M., and Roth, M. B. (2002). Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans. Mol. Biol. Cell 13, 1473-1483.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1473-1483
-
-
Padilla, P.A.1
Nystul, T.G.2
Zager, R.A.3
Johnson, A.C.M.4
Roth, M.B.5
-
130
-
-
84860727307
-
Suspended animation, diapause and quiescence: arresting the cell cycle in C. elegans
-
Padilla, P. A., and Ladage, M. L. (2012). Suspended animation, diapause and quiescence: arresting the cell cycle in C. elegans. Cell Cycle 11, 1672-1679.
-
(2012)
Cell Cycle
, vol.11
, pp. 1672-1679
-
-
Padilla, P.A.1
Ladage, M.L.2
-
131
-
-
33846418352
-
Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
-
Pan, K. Z., Palter, J. E., Rogers, A. N., Olsen, A., Chen, D., Lithgow, G. J., et al. (2007). Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6, 111-119.
-
(2007)
Aging Cell
, vol.6
, pp. 111-119
-
-
Pan, K.Z.1
Palter, J.E.2
Rogers, A.N.3
Olsen, A.4
Chen, D.5
Lithgow, G.J.6
-
132
-
-
52149101812
-
Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L
-
Papandreou, I., Lim, A. L., Laderoute, K., andDenko, N. C. (2008). Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3, and BNIP3L. Cell Death Differ. 15, 1572-1581.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1572-1581
-
-
Papandreou, I.1
Lim, A.L.2
Laderoute, K.3
Denko, N.C.4
-
133
-
-
33747376305
-
Hypoxia protects HepG2 cells against etoposide-induced apoptosis via a HIF-1-independent pathway
-
Piret, J.-P., Cosse, J.-P., Ninane, N., Raes, M., and Michiels, C. (2006). Hypoxia protects HepG2 cells against etoposide-induced apoptosis via a HIF-1-independent pathway. Exp. Cell Res. 312,2908-2920.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 2908-2920
-
-
Piret, J.-P.1
Cosse, J.-P.2
Ninane, N.3
Raes, M.4
Michiels, C.5
-
134
-
-
48149113439
-
Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
-
Pocock, R., and Hobert, O. (2008). Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans. Nat. Neurosci. 11, 894-900.
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 894-900
-
-
Pocock, R.1
Hobert, O.2
-
135
-
-
77954310408
-
Hypoxia signaling and resistance in C. elegans
-
Powell-Coffman, J. A. (2010). Hypoxia signaling and resistance in C. elegans. Trends Endocrinol Metab. 21, 435-440.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 435-440
-
-
Powell-Coffman, J.A.1
-
136
-
-
46149107882
-
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
-
Raffaghello, L., Lee, C., Safdie, F. M., Wei, M., Madia, F., Bianchi, G., et al. (2008). Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy. Proc. Natl. Acad. Sci. U.S.A. 105,8215-8220.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 8215-8220
-
-
Raffaghello, L.1
Lee, C.2
Safdie, F.M.3
Wei, M.4
Madia, F.5
Bianchi, G.6
-
137
-
-
78649882284
-
Fasting and differential chemotherapy protection in patients
-
Raffaghello, L., Safdie, F., Bianchi, G., Dorff, T., Fontana, L., and Longo, V. D. (2010). Fasting and differential chemotherapy protection in patients. Cell Cycle 9, 4474-4476.
-
(2010)
Cell Cycle
, vol.9
, pp. 4474-4476
-
-
Raffaghello, L.1
Safdie, F.2
Bianchi, G.3
Dorff, T.4
Fontana, L.5
Longo, V.D.6
-
138
-
-
77957845608
-
Lifespan and oxidative stress show a non-linear response to atmospheric oxygen in Drosophila
-
Rascón, B., and Harrison, J. F. (2010). Lifespan and oxidative stress show a non-linear response to atmospheric oxygen in Drosophila. J. Exp. Biol. 213,3441-3448.
-
(2010)
J. Exp. Biol.
, vol.213
, pp. 3441-3448
-
-
Rascón, B.1
Harrison, J.F.2
-
140
-
-
33645778794
-
Temperature regulates hypoxia-inducible factor-1 (HIF-1) in a poikilothermic vertebrate, crucian carp (Carassius carassius)
-
Rissanen, E., Tranberg, H. K., Sollid, J., Nilsson, G. E., and Nikinmaa, M. (2006). Temperature regulates hypoxia-inducible factor-1 (HIF-1) in a poikilothermic vertebrate, crucian carp (Carassius carassius). J. Exp. Biol. 209, 994-1003.
-
(2006)
J. Exp. Biol.
, vol.209
, pp. 994-1003
-
-
Rissanen, E.1
Tranberg, H.K.2
Sollid, J.3
Nilsson, G.E.4
Nikinmaa, M.5
-
141
-
-
84860461929
-
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
-
Robida-Stubbs, S., Glover-Cutter, K., Lamming, D. W., Mizunuma, M., Narasimhan, S. D., Neumann-Haefelin, E., et al. (2012). TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metab. 15, 713-724.
-
(2012)
Cell Metab
, vol.15
, pp. 713-724
-
-
Robida-Stubbs, S.1
Glover-Cutter, K.2
Lamming, D.W.3
Mizunuma, M.4
Narasimhan, S.D.5
Neumann-Haefelin, E.6
-
142
-
-
82755195292
-
Tumor cell metabolism: an integral view
-
Romero-Garcia, S., Lopez-Gonzalez, J. S., Báez-Viveros, J. L., Aguilar-Cazares, D., and Prado-Garcia, H. (2011). Tumor cell metabolism: an integral view. Cancer Biol. Ther. 12, 939-948.
-
(2011)
Cancer Biol. Ther.
, vol.12
, pp. 939-948
-
-
Romero-Garcia, S.1
Lopez-Gonzalez, J.S.2
Báez-Viveros, J.L.3
Aguilar-Cazares, D.4
Prado-Garcia, H.5
-
143
-
-
68349135032
-
Regulation of autophagy through multiple independent hypoxic signaling pathways
-
Rouschop, K. M., and Wouters, B. G. (2009). Regulation of autophagy through multiple independent hypoxic signaling pathways. Curr. Mol.Med. 9,417-424.
-
(2009)
Curr. Mol.Med.
, vol.9
, pp. 417-424
-
-
Rouschop, K.M.1
Wouters, B.G.2
-
144
-
-
58149089765
-
Autophagy protects against hypoxic injury in C. elegans
-
Samokhvalov, V., Scott, B. A., and Crowder, C. M. (2008). Autophagy protects against hypoxic injury in C. elegans. Autophagy 4, 1034-1041.
-
(2008)
Autophagy
, vol.4
, pp. 1034-1041
-
-
Samokhvalov, V.1
Scott, B.A.2
Crowder, C.M.3
-
145
-
-
38549125566
-
Egg-laying
-
Schafer, W. R. (2005). Egg-laying. WormBook, 1-7.
-
(2005)
WormBook
, pp. 1-7
-
-
Schafer, W.R.1
-
146
-
-
38649123072
-
Conserved metabolic regulatory functions of sirtuins
-
Schwer, B., and Verdin, E. (2008). Conserved metabolic regulatory functions of sirtuins. Cell Metab. 7, 104-112.
-
(2008)
Cell Metab
, vol.7
, pp. 104-112
-
-
Schwer, B.1
Verdin, E.2
-
147
-
-
0037189303
-
Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2
-
Scott, B. A., Avidan, M. S., and Crowder, C. M. (2002). Regulation of hypoxic death in C. elegans by the insulin/IGF receptor homolog DAF-2. Science 296,2388-2391.
-
(2002)
Science
, vol.296
, pp. 2388-2391
-
-
Scott, B.A.1
Avidan, M.S.2
Crowder, C.M.3
-
148
-
-
82555184793
-
The oogenic germline starvation response in C. elegans
-
doi:10.1371/journal.pone.0028074
-
Seidel, H. S., and Kimble, J. (2011). The oogenic germline starvation response in C. elegans. PLoS ONE 6, e28074. doi: 10.1371/journal.pone.0028074
-
(2011)
PLoS ONE
, vol.6
-
-
Seidel, H.S.1
Kimble, J.2
-
149
-
-
77952267258
-
State of the science: hypoxic ischemic encephalopathy and hypothermic intervention for neonates
-
Selway, L. D. (2010). State of the science: hypoxic ischemic encephalopathy and hypothermic intervention for neonates. Adv. Neonatal Care 10, 60-66.
-
(2010)
Adv. Neonatal Care
, vol.10
, pp. 60-66
-
-
Selway, L.D.1
-
150
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
Semenza, G. L. (2009). Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology (Bethesda) 24, 97-106.
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 97-106
-
-
Semenza, G.L.1
-
151
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
Semenza, G. L. (2010). Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics. Oncogene 29, 625-634.
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
152
-
-
80051625243
-
Oxygen sensing, homeostasis, and disease
-
Semenza, G. L. (2011). Oxygen sensing, homeostasis, and disease. N. Engl. J. Med. 365, 537-547.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 537-547
-
-
Semenza, G.L.1
-
153
-
-
84856739946
-
Hypoxia-inducible factors in physiology and medicine
-
Semenza, G. L. (2012). Hypoxia-inducible factors in physiology and medicine. Cell 148, 399-408.
-
(2012)
Cell
, vol.148
, pp. 399-408
-
-
Semenza, G.L.1
-
154
-
-
84873152384
-
The VHL/HIF axis in clear cell renal carcinoma
-
Shen, C., and Kaelin, W. G. Jr. (2012). The VHL/HIF axis in clear cell renal carcinoma. Semin. Cancer Biol. 483, 484-488.
-
(2012)
Semin. Cancer Biol
, vol.483
, pp. 484-488
-
-
Shen, C.1
Kaelin Jr, W.G.2
-
155
-
-
0038468454
-
Genetic analysis of hypoxia signaling and response in C. elegans
-
Shen, C., and Powell-Coffman, J. A. (2003). Genetic analysis of hypoxia signaling and response in C. elegans. Ann. N Y. Acad. Sci. 995, 191-199.
-
(2003)
Ann. N Y. Acad. Sci.
, vol.995
, pp. 191-199
-
-
Shen, C.1
Powell-Coffman, J.A.2
-
156
-
-
20144362749
-
Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans
-
Shen, C., Nettleton, D., Jiang, M., Kim, S. K., and Powell-Coffman, J. A. (2005). Roles of the HIF-1 hypoxia-inducible factor during hypoxia response in Caenorhabditis elegans. J. Biol. Chem. 280,20580-20588.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20580-20588
-
-
Shen, C.1
Nettleton, D.2
Jiang, M.3
Kim, S.K.4
Powell-Coffman, J.A.5
-
157
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
Simonsen, A., Cumming, R. C., Brech, A., Isakson, P., Schubert, D. R., and Finley, K. D. (2008). Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila. Autophagy 4, 176-184.
-
(2008)
Autophagy
, vol.4
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
158
-
-
3142729014
-
Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine
-
Stipanuk, M. H. (2004). Sulfur amino acid metabolism: pathways for production and removal of homocysteine and cysteine. Annu. Rev. Nutr. 24,539-577.
-
(2004)
Annu. Rev. Nutr.
, vol.24
, pp. 539-577
-
-
Stipanuk, M.H.1
-
159
-
-
1442291120
-
Metabolic rate depression in animals: transcriptional and translational controls
-
Storey, K. B., and Storey, J. M. (2004). Metabolic rate depression in animals: transcriptional and translational controls. Biol. Rev. Camb. Philos. Soc. 79, 207-233.
-
(2004)
Biol. Rev. Camb. Philos. Soc.
, vol.79
, pp. 207-233
-
-
Storey, K.B.1
Storey, J.M.2
-
160
-
-
79955580819
-
Therapeutic hypothermia after cardiac arrest: where are we now? Curr
-
Sunde, K., and Søreide, E. (2011). Therapeutic hypothermia after cardiac arrest: where are we now? Curr. Opin. Crit. Care 17,247-253.
-
(2011)
Opin. Crit. Care
, vol.17
, pp. 247-253
-
-
Sunde, K.1
Søreide, E.2
-
161
-
-
84855886815
-
Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan
-
Swindell, W. R. (2012). Dietary restriction in rats and mice: a meta-analysis and review of the evidence for genotype-dependent effects on lifespan. Ageing Res. Rev. 11, 254-270.
-
(2012)
Ageing Res. Rev.
, vol.11
, pp. 254-270
-
-
Swindell, W.R.1
-
162
-
-
35748959038
-
Hydrogen sulphide and its therapeutic potential
-
Szabó, C. (2007). Hydrogen sulphide and its therapeutic potential. Nat. Rev. DrugDiscov. 6, 917-935.
-
(2007)
Nat. Rev. DrugDiscov.
, vol.6
, pp. 917-935
-
-
Szabó, C.1
-
163
-
-
38749134454
-
Regulation of gonad development and respiratory metabolism associated with food availability and reproductive diapause in the rice bug Leptocorisa chinensis
-
Tachibana, S.-I., and Watanabe, T. (2008). Regulation of gonad development and respiratory metabolism associated with food availability and reproductive diapause in the rice bug Leptocorisa chinensis. J. Insect Physiol. 54,445-453.
-
(2008)
J. Insect Physiol.
, vol.54
, pp. 445-453
-
-
Tachibana, S.-I.1
Watanabe, T.2
-
164
-
-
59849109415
-
Essential role of SBP-1 activation in oxygen deprivation induced lipid accumulation and increase in body width/length ratio in Caenorhabditis elegans
-
Taghibiglou, C., Martin, H. G. S., Rose, J. K., Ivanova, N., Lin, C. H. C., Lau, H. L., et al. (2009). Essential role of SBP-1 activation in oxygen deprivation induced lipid accumulation and increase in body width/length ratio in Caenorhabditis elegans. FEBS Lett. 583,831-834.
-
(2009)
FEBS Lett
, vol.583
, pp. 831-834
-
-
Taghibiglou, C.1
Martin, H.G.S.2
Rose, J.K.3
Ivanova, N.4
Lin, C.H.C.5
Lau, H.L.6
-
165
-
-
84860701457
-
In vivo up-regulation of the unfolded protein response after hypoxia
-
Tagliavacca, L., Caretti, A., Bianciardi, P., and Samaja, M. (2012). In vivo up-regulation of the unfolded protein response after hypoxia. Biochim. Biophys. Acta 1820, 900-906.
-
(2012)
Biochim. Biophys. Acta
, vol.1820
, pp. 900-906
-
-
Tagliavacca, L.1
Caretti, A.2
Bianciardi, P.3
Samaja, M.4
-
166
-
-
0001263703
-
Negligible senescence during reproductive dormancy in Drosophila melanogaster
-
Tatar, M., Chien, S. A., and Priest, N. K. (2001). Negligible senescence during reproductive dormancy in Drosophila melanogaster. Am. Nat. 158,248-258.
-
(2001)
Am. Nat.
, vol.158
, pp. 248-258
-
-
Tatar, M.1
Chien, S.A.2
Priest, N.K.3
-
167
-
-
0031106001
-
Balancing hypoxia and hypothermia in cold-submerged frogs
-
Tattersall, G. J., and Boutilier, R. G. (1997). Balancing hypoxia and hypothermia in cold-submerged frogs. J. Exp. Biol. 200, 1031-1038.
-
(1997)
J. Exp. Biol.
, vol.200
, pp. 1031-1038
-
-
Tattersall, G.J.1
Boutilier, R.G.2
-
168
-
-
77950865453
-
Hydrogen sulfide protects neurons against hypoxic injury via stimulation of ATP-sensitive potassium channel/protein kinase C/extracellular signal-regulated kinase/heat shock protein 90 pathway
-
Tay, A. S., Hu, L. F., Lu, M., Wong, P. T. H., and Bian, J. S. (2010). Hydrogen sulfide protects neurons against hypoxic injury via stimulation of ATP-sensitive potassium channel/protein kinase C/extracellular signal-regulated kinase/heat shock protein 90 pathway. Neuroscience 167, 277-286.
-
(2010)
Neuroscience
, vol.167
, pp. 277-286
-
-
Tay, A.S.1
Hu, L.F.2
Lu, M.3
Wong, P.T.H.4
Bian, J.S.5
-
170
-
-
0037415685
-
Nitric oxide-induced suspended animation promotes survival during hypoxia
-
Teodoro, R. O., and O'Farrell, P. H. (2003). Nitric oxide-induced suspended animation promotes survival during hypoxia. EMBO J. 22, 580-587.
-
(2003)
EMBO J
, vol.22
, pp. 580-587
-
-
Teodoro, R.O.1
O'Farrell, P.H.2
-
171
-
-
0037787922
-
Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times
-
Theissen, U., Hoffmeister, M., Grieshaber, M., and Martin, W. (2003). Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times. Mol. Biol. Evol. 20, 1564-1574.
-
(2003)
Mol. Biol. Evol.
, vol.20
, pp. 1564-1574
-
-
Theissen, U.1
Hoffmeister, M.2
Grieshaber, M.3
Martin, W.4
-
172
-
-
0043128522
-
HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans
-
Treinin, M., Shliar, J., Jiang, H., Powell-Coffman, J. A., Bromberg, Z., and Horowitz, M. (2003). HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans. Physiol. Genomics 14, 17-24.
-
(2003)
Physiol. Genomics
, vol.14
, pp. 17-24
-
-
Treinin, M.1
Shliar, J.2
Jiang, H.3
Powell-Coffman, J.A.4
Bromberg, Z.5
Horowitz, M.6
-
173
-
-
0036862532
-
The FAD- and O2-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum
-
Tu, B. P., and Weissman, J. S. (2002). The FAD- and O2-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum. Mol. Cell 10, 983-994.
-
(2002)
Mol. Cell
, vol.10
, pp. 983-994
-
-
Tu, B.P.1
Weissman, J.S.2
-
174
-
-
40849118472
-
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
-
Tullet, J. M. A., Hertweck, M., An, J. H., Baker, J., Hwang, J. Y., Liu, S., et al. (2008). Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132, 1025-1038.
-
(2008)
Cell
, vol.132
, pp. 1025-1038
-
-
Tullet, J.M.A.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Hwang, J.Y.5
Liu, S.6
-
175
-
-
33644876383
-
Dietary restriction compromises resistance to gut ischemia-reperfusion, despite reduction in circulating leukocyte activation
-
Ueno, C., Fukatsu, K., Maeshima, Y., Moriya, T., Shinto, E., Hara, E., et al. (2005). Dietary restriction compromises resistance to gut ischemia-reperfusion, despite reduction in circulating leukocyte activation. J. Parenter. Enteral Nutr. 29, 345-352.
-
(2005)
J. Parenter. Enteral Nutr.
, vol.29
, pp. 345-352
-
-
Ueno, C.1
Fukatsu, K.2
Maeshima, Y.3
Moriya, T.4
Shinto, E.5
Hara, E.6
-
176
-
-
84862508732
-
Hydrogen sulfide: a gaso-transmitter of clinical relevance
-
Vandiver, M. S., and Snyder, S. H. (2012). Hydrogen sulfide: a gaso-transmitter of clinical relevance. J. Mol. Med. (Berl) 90, 255-263.
-
(2012)
J. Mol. Med. (Berl)
, vol.90
, pp. 255-263
-
-
Vandiver, M.S.1
Snyder, S.H.2
-
177
-
-
0033613204
-
Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate
-
Van Voorhies, W. A., and Ward, S. (1999). Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate. Proc. Natl. Acad. Sci. U.S.A. 96, 11399-11403.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 11399-11403
-
-
Van Voorhies, W.A.1
Ward, S.2
-
178
-
-
82955196857
-
Preoperative fasting protects mice against hepatic ischemia/reperfusion injury: mechanisms and effects on liver regeneration
-
Verweij, M., van Ginhoven, T. M., Mitchell, J. R., Sluiter, W., van den Engel, S., Roest, H. P., et al. (2011). Preoperative fasting protects mice against hepatic ischemia/reperfusion injury: mechanisms and effects on liver regeneration. Liver Transpl. 17, 695-704.
-
(2011)
Liver Transpl
, vol.17
, pp. 695-704
-
-
Verweij, M.1
van Ginhoven, T.M.2
Mitchell, J.R.3
Sluiter, W.4
van den Engel, S.5
Roest, H.P.6
-
179
-
-
35848947531
-
Plasticity of the responses to chronic hypoxia and dietary restriction in an aged organism: evidence from the Drosophila model
-
Vigne, P., and Frelin, C. (2007). Plasticity of the responses to chronic hypoxia and dietary restriction in an aged organism: evidence from the Drosophila model. Exp. Gerontol. 42, 1162-1166.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 1162-1166
-
-
Vigne, P.1
Frelin, C.2
-
180
-
-
65549123532
-
Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries
-
doi:10.1371/journal.pone.0005422
-
Vigne, P., Tauc, M., and Frelin, C. (2009). Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries. PLoS ONE 4, e5422. doi: 10.1371/journal.pone.0005422
-
(2009)
PLoS ONE
, vol.4
-
-
Vigne, P.1
Tauc, M.2
Frelin, C.3
-
181
-
-
41149146946
-
Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse
-
Volpato, G. P., Searles, R., Yu, B., Scherrer-Crosbie, M., Bloch, K. D., Ichinose, F., et al. (2008). Inhaled hydrogen sulfide: a rapidly reversible inhibitor of cardiac and metabolic function in the mouse. Anesthesiology 108, 659-668.
-
(2008)
Anesthesiology
, vol.108
, pp. 659-668
-
-
Volpato, G.P.1
Searles, R.2
Yu, B.3
Scherrer-Crosbie, M.4
Bloch, K.D.5
Ichinose, F.6
-
182
-
-
0027427588
-
Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
-
Wang, G. L., and Semenza, G. L. (1993). Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J. Biol. Chem. 268,21513-21518.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21513-21518
-
-
Wang, G.L.1
Semenza, G.L.2
-
183
-
-
84860117196
-
Physiological implications of hydrogen sulfide: a whiff exploration that blossomed
-
Wang, R. (2012). Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. Physiol. Rev. 92,791-796.
-
(2012)
Physiol. Rev.
, vol.92
, pp. 791-796
-
-
Wang, R.1
-
184
-
-
58749099124
-
SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention - the TULIP Study
-
doi:10.1186/1471-2350-9-100
-
Weyrich, P., Machicao, F., Reinhardt, J., Machann, J., Schick, F., Tschritter, O., et al. (2008). SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention - the TULIP Study. BMC Med. Genet. 9, 100. doi: 10.1186/1471-2350-9-100
-
(2008)
BMC Med. Genet.
, vol.9
, pp. 100
-
-
Weyrich, P.1
Machicao, F.2
Reinhardt, J.3
Machann, J.4
Schick, F.5
Tschritter, O.6
-
185
-
-
33751351093
-
Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans
-
Wheeler, J. M., and Thomas, J. H. (2006). Identification of a novel gene family involved in osmotic stress response in Caenorhabditis elegans. Genetics 174,1327-1336.
-
(2006)
Genetics
, vol.174
, pp. 1327-1336
-
-
Wheeler, J.M.1
Thomas, J.H.2
-
186
-
-
24344485624
-
Control of the hypoxic response through regulation of mRNA translation
-
Wouters, B. G., van den Beucken, T., Magagnin, M. G., Koritzinsky, M., Fels, D., and Koumenis, C. (2005). Control of the hypoxic response through regulation of mRNA translation. Semin. Cell Dev. Biol. 16, 487-501.
-
(2005)
Semin. Cell Dev. Biol.
, vol.16
, pp. 487-501
-
-
Wouters, B.G.1
van den Beucken, T.2
Magagnin, M.G.3
Koritzinsky, M.4
Fels, D.5
Koumenis, C.6
-
187
-
-
33745654084
-
SIRT1 and endocrine signaling
-
Yang, T., Fu, M., Pestell, R., and Sauve, A. A. (2006). SIRT1 and endocrine signaling. Trends Endocrinol. Metab. 17, 186-191.
-
(2006)
Trends Endocrinol. Metab.
, vol.17
, pp. 186-191
-
-
Yang, T.1
Fu, M.2
Pestell, R.3
Sauve, A.A.4
-
188
-
-
84858706456
-
Neuroprotective mechanisms of hypothermia in brain ischaemia
-
Yenari, M. A., and Han, H. S. (2012). Neuroprotective mechanisms of hypothermia in brain ischaemia. Nat. Rev. Neurosci. 13, 267-278.
-
(2012)
Nat. Rev. Neurosci.
, vol.13
, pp. 267-278
-
-
Yenari, M.A.1
Han, H.S.2
-
189
-
-
77951887561
-
Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers
-
Yin, J., Miyazaki, K., Shaner, R. L., Merrill, A. H., and Kannagi, R. (2010). Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers. FEBS Lett. 584, 1872-1878.
-
(2010)
FEBS Lett
, vol.584
, pp. 1872-1878
-
-
Yin, J.1
Miyazaki, K.2
Shaner, R.L.3
Merrill, A.H.4
Kannagi, R.5
-
190
-
-
0035030625
-
Sulfide oxidation coupled to ATP synthesis in chicken liver mitochondria
-
Yong, R., and Searcy, D. G. (2001). Sulfide oxidation coupled to ATP synthesis in chicken liver mitochondria. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 129, 129-137.
-
(2001)
Comp. Biochem. Physiol. B. Biochem. Mol. Biol.
, vol.129
, pp. 129-137
-
-
Yong, R.1
Searcy, D.G.2
-
191
-
-
70350441907
-
The role of sirtuins in the control of metabolic homeostasis
-
Yu, J., and Auwerx, J. (2009). The role of sirtuins in the control of metabolic homeostasis. Ann. N Y. Acad. Sci. 1173(Suppl. 1), E10-E19.
-
(2009)
Ann. N Y. Acad. Sci.
, vol.1173
, Issue.SUPPL. 1
-
-
Yu, J.1
Auwerx, J.2
-
192
-
-
0001611514
-
Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism
-
Yu, Z. F., and Mattson, M. P. (1999). Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism. J. Neurosci. Res. 57, 830-839.
-
(1999)
J. Neurosci. Res.
, vol.57
, pp. 830-839
-
-
Yu, Z.F.1
Mattson, M.P.2
-
193
-
-
79960897419
-
Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation
-
doi:10.1371/journal.pbio.1001112
-
Zhang, H., Zhang, G., Gonzalez, E J., Park, S.-M., and Cai, D. (2011). Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation. PLoS Biol. 9, e1001112. doi: 10.1371/journal.pbio.1001112
-
(2011)
PLoS Biol
, vol.9
-
-
Zhang, H.1
Zhang, G.2
Gonzalez, E.J.3
Park, S.-M.4
Cai, D.5
-
194
-
-
68149149835
-
The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans
-
doi:10.1371/journal.pone.0006348
-
Zhang, Y., Shao, Z., Zhai, Z., Shen, C., and Powell-Coffman, J. A. (2009). The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans. PLoS ONE 4, e6348. doi: 10.1371/journal.pone.0006348
-
(2009)
PLoS ONE
, vol.4
-
-
Zhang, Y.1
Shao, Z.2
Zhai, Z.3
Shen, C.4
Powell-Coffman, J.A.5
-
195
-
-
84863474509
-
Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP
-
Zheng, X., Zheng, X., Wang, X., Ma, Z., Gupta Sunkari, V., Botusan, I., et al. (2012). Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP. Cell Death Dis. 3, e322.
-
(2012)
Cell Death Dis
, vol.3
-
-
Zheng, X.1
Zheng, X.2
Wang, X.3
Ma, Z.4
Gupta Sunkari, V.5
Botusan, I.6
|