Suspended Animation in C. elegans Requires the Spindle Checkpoint

Science

Volumn 302, Issue 5647, 2003, Pages 1038-1041

  Nystul, Todd G ^a   Goldmark, Jesse P ^a   Padilla, Pamela A ^b   Roth, Mark B ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF NORTH TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMATION; CELLS; DATA REDUCTION; GENES; MICROSCOPIC EXAMINATION;

ENVIRONMENTAL SIGNALS;

MICROORGANISMS;

ANOXIA; GENE;

ARTICLE; CAENORHABDITIS ELEGANS; CELL CYCLE; CELL HYPOXIA; CELL VIABILITY; CHROMOSOME STRUCTURE; GENE; GENE IDENTIFICATION; MITOSIS INHIBITION; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL; SAN 1 GENE;

ANAPHASE; ANEUPLOIDY; ANIMALS; BLASTOMERES; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL CYCLE PROTEINS; CHROMOSOME SEGREGATION; GENES, HELMINTH; METAPHASE; MITOSIS; MITOTIC SPINDLE APPARATUS; OPEN READING FRAMES; OXYGEN; RNA INTERFERENCE; TELOPHASE;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; INVERTEBRATA; NEMATODA;

EID: 0242494080     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1089705     Document Type: Article

References (25)

1. M. B. Renfree, G. Shaw, Annu. Rev. Physiol. 62, 353 (2000).
2. P. A. Padilta, M. B. Roth, Proc. Natl. Acad. Sci. U.S.A. 98, 7331 (2001).
3. J. E. Podrabsky, S. C. Hand, J. Exp. Biol. 202 (Pt 19), 2567 (1999).
4. V. E. Foe, B. M. Alberts, J. Cell. Biol. 100, 1623 (1985).
5. J. Clegg, J. Exp. Biol. 200, 467 (1997).
6. D. C. Jackson, J. Physiol. 543, 731 (2002).
7. K. B. Storey, Comp. Biochem. Physiol. Part A Mol. Integr. Physiol. 133, 733 (2002).
8. P. Safar et al., Crit. Care Med. 28, N214 (2000).
9. H. B. Alam et al., Surgery 132, 278 (2002).
10. P. A. Padilla, T. G. Nystul, R. A. Zager, A. C. Johnson, M. B. Roth, Mol. Biol. Cell. 13, 1473 (2002).
11. J. Lopez-Barneo, R. Pardal, P. Ortega-Saenz, Annu. Rev. Physiol. 63, 259 (2001).
12. P. W. Hochachka, L. T. Buck, C. J. Doll, S. C. Land, Proc. Natl. Acad. Sci. U.S.A. 93, 9493 (1996).
13. G. L. Semenza, Cell 107, 1 (2001).
14. K. Guillemin, M. A. Krasnow, Cell 89, 9 (1997).
15. H. Jiang, R. Guo, J. A. Powell-Coffman, Proc. Natl. Acad. Sci. U.S.A. 98, 7916 (2001).
16. A. G. Fraser et al., Nature 408, 325 (2000).
17. T. G. Nystul, J. P. Goldmark, P. A. Padilla, M. B. Roth, data not shown.
18. B. J. Buchwitz, K. Ahmad, L. L. Moore, M. B. Roth, S. Henikoff, Nature 401, 547 (1999).
19. R. Kitagawa, A. M. Rose, Nature Cell. Biol. 1, 514 (1999).
20. K. G. Hardwick, R. C. Johnston, D. L. Smith, A. W. Murray, J. Cell Biol. 148, 871 (2000).
21. S. S. Taylor, E. Ha, F. McKeon, J. Cell Biol. 142, 1 (1998).
22. Materials and methods are available as supplementary material on Science Online.
23. T. Fukushige, M. J. Hendzel, D. P. Bazett-Jones, J. D. McGhee, Proc. Natl. Acad. Sci. U.S.A. 96, 11883 (1999).
24. R. M. Douglas, G. G. Haddad, J. Appl. Physiol. 94, 2068 (2003).
25. The authors would like to thank T. Record and M. Capp for providing Lac1 repressor protein, J. McGhee for providing tagged nematode strain jm93, S. Biggins and B. Buchwitz for critical reading of the manuscript, J. Stear for advice and technical assistance, T. Stiernagle for providing nematode strains, and J. Ahringer and the Owning Organisation and Scientist and Distributing Organisation for making the Chromosome I RNAi Library available. Funding for this work was provided by NIH grant GM48435 to M.R. T.G.N. is supported by National Research Service award T32 GM07270, J.P.G. Is supported by an NSF Graduate Research Fellowship, and P.A.P. is supported by NSF Postdoctoral Fellowship 0112253, NSF Research Starter grant 0307491, and a University of North Texas Health Science Center American Cancer Society Institutional Research grant.