Inhibition of Na+/H+ exchanger 1 by 5-(N-ethyl-N-isopropyl) amiloride reduces hypoxia-induced hepatocellular carcinoma invasion and motility

Cancer Letters

Volumn 295, Issue 2, 2010, Pages 198-204

  Yang, Xuekang ^a   Wang, Desheng ^a   Dong, Wei ^a   Song, Zhenshun ^a   Dou, Kefeng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Hepatocellular carcinoma; Invasion; Migration; Na+ H+ exchanger 1; Tumor microenvironment

Indexed keywords

5 (N ETHYL N ISOPROPYL)AMILORIDE; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SODIUM PROTON EXCHANGE PROTEIN 1; VASCULOTROPIN;

ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL MIGRATION; CELL PH; CELL STRAIN HEPG2; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SYNTHESIS; HYPOXIA; INHIBITION KINETICS; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; WESTERN BLOTTING;

AMILORIDE; CARCINOMA, HEPATOCELLULAR; CATION TRANSPORT PROTEINS; CELL HYPOXIA; CELL MOVEMENT; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LIVER NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; SODIUM-HYDROGEN ANTIPORTER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77954034986     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.03.001     Document Type: Article

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