Physiology, pharmacology and pathophysiology of the ph regulatory transport proteins NHE1 and NBCN1: Similarities, differences, and implications for cancer therapy

Current Pharmaceutical Design

Volumn 18, Issue 10, 2012, Pages 1345-1371

  Boedtkjer, E ^a   Bunch, L ^b   Pedersen, S F ^c  

^a AARHUS UNIVERSITY   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Acidification; Bicarbonate; Cancer; Cariporide; DIDS; EIPA; S0859; SLC4A7; SLC9A1

Indexed keywords

5 (N,N DIMETHYL)AMILORIDE; 5' N ETHYLISOPROPYLAMILORIDE; AMILORIDE; CALMODULIN; CARIPORIDE; CARRIER PROTEINS AND BINDING PROTEINS; CIMETIDINE; ENIPORIDE; EZRIN; GUANIDINE DERIVATIVE; HARMALINE; HEAT SHOCK PROTEIN 70; HEMOGLOBIN; IMIDAZOLINE DERIVATIVE; KR 32570; KR 33028; MOESIN; NBCN1 PROTEIN; POTASSIUM SPARING DIURETIC AGENT; PROTEIN INHIBITOR; PYRAZINE DERIVATIVE; RADIXIN; SABIPORIDE; SL 591227; SODIUM PROTON EXCHANGE PROTEIN; SODIUM PROTON EXCHANGE PROTEIN 1; SODIUM PROTON EXCHANGE PROTEIN 1 INHIBITOR; T 162559; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZONIPORIDE;

APOPTOSIS; ARTICLE; BINDING SITE; BLOOD; CANCER CELL; CANCER THERAPY; CARDIOVASCULAR SYSTEM; CELL DEATH; CELL FUNCTION; CELL HYPOXIA; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CIRCULAR DICHROISM; CLINICAL TRIAL (TOPIC); CRYSTAL STRUCTURE; CYTOSOL; DIMERIZATION; DRUG MECHANISM; DRUG TARGETING; GASTROINTESTINAL TRACT; GENE EXPRESSION; HEART DISEASE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HOMEOSTASIS; HUMAN; IC 50; IMMUNE SYSTEM; IN VITRO GENE TRANSFER; IN VIVO STUDY; KIDNEY; NEOPLASM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXYGEN SATURATION; PATHOPHYSIOLOGY; PHARMACOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PULMONARY HYPERTENSION; REGULATORY MECHANISM; REPERFUSION INJURY; STOICHIOMETRY; X RAY CRYSTALLOGRAPHY;

EID: 84857735672     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/138161212799504830     Document Type: Article

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