-
1
-
-
7444223594
-
Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells
-
KA Ahmad KB Iskandar JL Hirpara MV Clement S Pervaiz 2004 Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells Cancer Res 64 7867 7878
-
(2004)
Cancer Res
, vol.64
, pp. 7867-7878
-
-
Ahmad, K.A.1
Iskandar, K.B.2
Hirpara, J.L.3
Clement, M.V.4
Pervaiz, S.5
-
2
-
-
33644816650
-
Molecular physiology of SLC4 anion exchangers
-
SL Alper 2006 Molecular physiology of SLC4 anion exchangers Exp Physiol 91 153 161
-
(2006)
Exp Physiol
, vol.91
, pp. 153-161
-
-
Alper, S.L.1
-
3
-
-
0029032815
-
Extracellular and intracellular alkalinization and the constriction of rat cerebral arterioles
-
M Apkon WF Boron 1995 Extracellular and intracellular alkalinization and the constriction of rat cerebral arterioles J Physiol 484 Pt 3 743 753
-
(1995)
J Physiol
, vol.484
, Issue.PART 3
, pp. 743-753
-
-
Apkon, M.1
Boron, W.F.2
-
4
-
-
58149390625
-
Targeting Src signaling in metastatic bone disease
-
J Araujo C Logothetis 2009 Targeting Src signaling in metastatic bone disease Int J Cancer 124 1 6
-
(2009)
Int J Cancer
, vol.124
, pp. 1-6
-
-
Araujo, J.1
Logothetis, C.2
-
6
-
-
0035858878
-
Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts
-
KA Beningo M Dembo I Kaverina JV Small YL Wang 2001 Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts J Cell Biol 153 881 888
-
(2001)
J Cell Biol
, vol.153
, pp. 881-888
-
-
Beningo, K.A.1
Dembo, M.2
Kaverina, I.3
Small, J.V.4
Wang, Y.L.5
-
7
-
-
59149085858
-
Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis
-
AM Bode YY Cho D Zheng F Zhu ME Ericson WY Ma K Yao Z Dong 2009 Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis Cancer Res 69 905 913
-
(2009)
Cancer Res
, vol.69
, pp. 905-913
-
-
Bode, A.M.1
Cho, Y.Y.2
Zheng, D.3
Zhu, F.4
Ericson, M.E.5
Ma, W.Y.6
Yao, K.7
Dong, Z.8
-
8
-
-
0035412186
-
Sodium-coupled bicarbonate transporters
-
WF Boron 2001 Sodium-coupled bicarbonate transporters Jop 2 176 181
-
(2001)
Jop
, vol.2
, pp. 176-181
-
-
Boron, W.F.1
-
9
-
-
0024194385
-
Role of monocarboxylate transport in the regulation of intracellular pH of renal proximal tubule cells
-
WF Boron AW Siebens NL Nakhoul 1988 Role of monocarboxylate transport in the regulation of intracellular pH of renal proximal tubule cells Ciba Found Symp 139 91 105
-
(1988)
Ciba Found Symp
, vol.139
, pp. 91-105
-
-
Boron, W.F.1
Siebens, A.W.2
Nakhoul, N.L.3
-
10
-
-
3042692979
-
CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion
-
LY Bourguignon PA Singleton F Diedrich R Stern E Gilad 2004 CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion J Biol Chem 279 26991 27007
-
(2004)
J Biol Chem
, vol.279
, pp. 26991-27007
-
-
Bourguignon, L.Y.1
Singleton, P.A.2
Diedrich, F.3
Stern, R.4
Gilad, E.5
-
11
-
-
47249143701
-
Integrin-associated proteins as potential therapeutic targets
-
JM Cantor MH Ginsberg DM Rose 2008 Integrin-associated proteins as potential therapeutic targets Immunol Rev 223 236 251
-
(2008)
Immunol Rev
, vol.223
, pp. 236-251
-
-
Cantor, J.M.1
Ginsberg, M.H.2
Rose, D.M.3
-
12
-
-
48549104131
-
Pollen tube growth oscillations and intracellular calcium levels are reversibly modulated by actin polymerization
-
L Cardenas A Lovy-Wheeler JG Kunkel PK Hepler 2008 Pollen tube growth oscillations and intracellular calcium levels are reversibly modulated by actin polymerization Plant Physiol 146 1611 1621
-
(2008)
Plant Physiol
, vol.146
, pp. 1611-1621
-
-
Cardenas, L.1
Lovy-Wheeler, A.2
Kunkel, J.G.3
Hepler, P.K.4
-
13
-
-
21844438240
-
Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines
-
RA Cardone A Bagorda A Bellizzi G Busco L Guerra A Paradiso V Casavola M Zaccolo SJ Reshkin 2005 Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines Mol Biol Cell 16 3117 3127
-
(2005)
Mol Biol Cell
, vol.16
, pp. 3117-3127
-
-
Cardone, R.A.1
Bagorda, A.2
Bellizzi, A.3
Busco, G.4
Guerra, L.5
Paradiso, A.6
Casavola, V.7
Zaccolo, M.8
Reshkin, S.J.9
-
14
-
-
25844528025
-
The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis
-
RA Cardone V Casavola SJ Reshkin 2005 The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis Nat Rev Cancer 5 786 795
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 786-795
-
-
Cardone, R.A.1
Casavola, V.2
Reshkin, S.J.3
-
15
-
-
58249094845
-
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH
-
J Chiche K Ilc J Laferriere E Trottier F Dayan NM Mazure MC Brahimi-Horn J Pouyssegur 2009 Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH Cancer Res 69 358 368
-
(2009)
Cancer Res
, vol.69
, pp. 358-368
-
-
Chiche, J.1
Ilc, K.2
Laferriere, J.3
Trottier, E.4
Dayan, F.5
Mazure, N.M.6
Brahimi-Horn, M.C.7
Pouyssegur, J.8
-
16
-
-
34250830244
-
The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration
-
YY Chuang A Valster SJ Coniglio JM Backer M Symons 2007 The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration J Cell Sci 120 1927 1934
-
(2007)
J Cell Sci
, vol.120
, pp. 1927-1934
-
-
Chuang, Y.Y.1
Valster, A.2
Coniglio, S.J.3
Backer, J.M.4
Symons, M.5
-
17
-
-
0035947085
-
Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa
-
CY Chung G Potikyan RA Firtel 2001 Control of cell polarity and chemotaxis by Akt/PKB and PI3 kinase through the regulation of PAKa Mol Cell 7 937 947
-
(2001)
Mol Cell
, vol.7
, pp. 937-947
-
-
Chung, C.Y.1
Potikyan, G.2
Firtel, R.A.3
-
18
-
-
31444441418
-
TRPM7, a novel regulator of actomyosin contractility and cell adhesion
-
K Clark M Langeslag B van Leeuwen L Ran AG Ryazanov CG Figdor WH Moolenaar K Jalink FN van Leeuwen 2006 TRPM7, a novel regulator of actomyosin contractility and cell adhesion EMBO J 25 290 301
-
(2006)
EMBO J
, vol.25
, pp. 290-301
-
-
Clark, K.1
Langeslag, M.2
Van Leeuwen, B.3
Ran, L.4
Ryazanov, A.G.5
Figdor, C.G.6
Moolenaar, W.H.7
Jalink, K.8
Van Leeuwen, F.N.9
-
19
-
-
0345059766
-
Intravital imaging of cell movement in tumours
-
J Condeelis JE Segall 2003 Intravital imaging of cell movement in tumours Nat Rev Cancer 3 921 930
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 921-930
-
-
Condeelis, J.1
Segall, J.E.2
-
20
-
-
8744300054
-
Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion
-
DR Critchley 2004 Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion Biochem Soc Trans 32 831 836
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 831-836
-
-
Critchley, D.R.1
-
21
-
-
48749116621
-
Exposure to occupational carcinogens and lung cancer risk. Evolution of epidemiological estimates of attributable fraction
-
S De Matteis D Consonni PA Bertazzi 2008 Exposure to occupational carcinogens and lung cancer risk. Evolution of epidemiological estimates of attributable fraction Acta Biomed 79 Suppl 1 34 42
-
(2008)
Acta Biomed
, vol.79
, Issue.SUPPL. 1
, pp. 34-42
-
-
De Matteis, S.1
Consonni, D.2
Bertazzi, P.A.3
-
22
-
-
0037164808
-
Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1
-
SP Denker DL Barber 2002 Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1 J Cell Biol 159 1087 1096
-
(2002)
J Cell Biol
, vol.159
, pp. 1087-1096
-
-
Denker, S.P.1
Barber, D.L.2
-
24
-
-
0344309120
-
The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site
-
JA Eble DS Tuckwell 2003 The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site Biochem J 376 77 85
-
(2003)
Biochem J
, vol.376
, pp. 77-85
-
-
Eble, J.A.1
Tuckwell, D.S.2
-
25
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
M Egeblad Z Werb 2002 New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2 161 174
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
-
26
-
-
42449113812
-
Cell-collagen interactions: The use of peptide Toolkits to investigate collagen-receptor interactions
-
RW Farndale T Lisman D Bihan S Hamaia CS Smerling N Pugh A Konitsiotis B Leitinger PG de Groot GE Jarvis N Raynal 2008 Cell-collagen interactions: the use of peptide Toolkits to investigate collagen-receptor interactions Biochem Soc Trans 36 241 250
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 241-250
-
-
Farndale, R.W.1
Lisman, T.2
Bihan, D.3
Hamaia, S.4
Smerling, C.S.5
Pugh, N.6
Konitsiotis, A.7
Leitinger, B.8
De Groot, P.G.9
Jarvis, G.E.10
Raynal, N.11
-
27
-
-
58149293622
-
Cofilin is a pH sensor for actin free barbed end formation: Role of phosphoinositide binding
-
C Frantz G Barreiro L Dominguez X Chen R Eddy J Condeelis MJ Kelly MP Jacobson DL Barber 2008 Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding J Cell Biol 183 865 879
-
(2008)
J Cell Biol
, vol.183
, pp. 865-879
-
-
Frantz, C.1
Barreiro, G.2
Dominguez, L.3
Chen, X.4
Eddy, R.5
Condeelis, J.6
Kelly, M.J.7
Jacobson, M.P.8
Barber, D.L.9
-
28
-
-
65249168811
-
Interaction of monocarboxylate transporter 4 with {beta}1-integrin and its role in cell migration
-
SM Gallagher JJ Castorino NJ Philp 2009 Interaction of monocarboxylate transporter 4 with {beta}1-integrin and its role in cell migration Am J Physiol Cell Physiol 296 C414 C421
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Gallagher, S.M.1
Castorino, J.J.2
Philp, N.J.3
-
31
-
-
33751206869
-
A role for p130Cas in mechanotransduction
-
B Geiger 2006 A role for p130Cas in mechanotransduction Cell 127 879 881
-
(2006)
Cell
, vol.127
, pp. 879-881
-
-
Geiger, B.1
-
32
-
-
0034093495
-
The pH difference between tumor and normal tissue offers a tumor specific target for the treatment of cancer
-
LE Gerweck 2000 The pH difference between tumor and normal tissue offers a tumor specific target for the treatment of cancer Drug Resist Updat 3 49 50
-
(2000)
Drug Resist Updat
, vol.3
, pp. 49-50
-
-
Gerweck, L.E.1
-
33
-
-
0029971428
-
Cellular pH gradient in tumor versus normal tissue: Potential exploitation for the treatment of cancer
-
LE Gerweck K Seetharaman 1996 Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer Cancer Res 56 1194 1198
-
(1996)
Cancer Res
, vol.56
, pp. 1194-1198
-
-
Gerweck, L.E.1
Seetharaman, K.2
-
34
-
-
33745110220
-
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
-
LE Gerweck S Vijayappa S Kozin 2006 Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics Mol Cancer Ther 5 1275 1279
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1275-1279
-
-
Gerweck, L.E.1
Vijayappa, S.2
Kozin, S.3
-
35
-
-
0025771650
-
Are cancer cells acidic?
-
JR Griffiths 1991 Are cancer cells acidic? Br J Cancer 64 425 427
-
(1991)
Br J Cancer
, vol.64
, pp. 425-427
-
-
Griffiths, J.R.1
-
36
-
-
44949234777
-
Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration
-
SC Grifoni SE McKey HA Drummond 2008 Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration Am J Physiol Heart Circ Physiol 294 H2022 2030
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
, pp. 2022-2030
-
-
Grifoni, S.C.1
Drummond, H.A.2
-
37
-
-
0027500849
-
Focal localization of the NHE-1 isoform of the Na+/H+ antiport: Assessment of effects on intracellular pH
-
S Grinstein M Woodside TK Waddell GP Downey J Orlowski J Pouyssegur DC Wong JK Foskett 1993 Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH EMBO J 12 5209 5218
-
(1993)
EMBO J
, vol.12
, pp. 5209-5218
-
-
Grinstein, S.1
Woodside, M.2
Waddell, T.K.3
Downey, G.P.4
Orlowski, J.5
Pouyssegur, J.6
Wong, D.C.7
Foskett, J.K.8
-
38
-
-
37349018272
-
The integrin-extracellular matrix axis in pancreatic cancer
-
JJ Grzesiak JC Ho AR Moossa M Bouvet 2007 The integrin-extracellular matrix axis in pancreatic cancer Pancreas 35 293 301
-
(2007)
Pancreas
, vol.35
, pp. 293-301
-
-
Grzesiak, J.J.1
Ho, J.C.2
Moossa, A.R.3
Bouvet, M.4
-
39
-
-
33751252276
-
Cancer metastasis: Building a framework
-
GP Gupta J Massague 2006 Cancer metastasis: building a framework Cell 127 679 695
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
40
-
-
1242340302
-
The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
-
AP Halestrap D Meredith 2004 The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond Pflugers Arch 447 619 628
-
(2004)
Pflugers Arch
, vol.447
, pp. 619-628
-
-
Halestrap, A.P.1
Meredith, D.2
-
41
-
-
24944481656
-
The role of pH dynamics and the Na+/H+ antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin-one single nature
-
S Harguindey G Orive J Luis Pedraz A Paradiso SJ Reshkin 2005 The role of pH dynamics and the Na+/H+ antiporter in the etiopathogenesis and treatment of cancer. Two faces of the same coin-one single nature Biochim Biophys Acta 1756 1 24
-
(2005)
Biochim Biophys Acta
, vol.1756
, pp. 1-24
-
-
Harguindey, S.1
Orive, G.2
Luis Pedraz, J.3
Paradiso, A.4
Reshkin, S.J.5
-
42
-
-
0036554644
-
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
-
G Helmlinger A Sckell M Dellian NS Forbes RK Jain 2002 Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism Clin Cancer Res 8 1284 1291
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1284-1291
-
-
Helmlinger, G.1
Sckell, A.2
Dellian, M.3
Forbes, N.S.4
Jain, R.K.5
-
43
-
-
55549090009
-
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes
-
M Hilvo L Baranauskiene AM Salzano A Scaloni D Matulis A Innocenti A Scozzafava SM Monti A Di Fiore G De Simone M Lindfors J Janis J Valjakka S Pastorekova J Pastorek MS Kulomaa HR Nordlund CT Supuran S Parkkila 2008 Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes J Biol Chem 283 27799 27809
-
(2008)
J Biol Chem
, vol.283
, pp. 27799-27809
-
-
Hilvo, M.1
Baranauskiene, L.2
Salzano, A.M.3
Scaloni, A.4
Matulis, D.5
Innocenti, A.6
Scozzafava, A.7
Monti, S.M.8
Di Fiore, A.9
De Simone, G.10
Lindfors, M.11
Janis, J.12
Valjakka, J.13
Pastorekova, S.14
Pastorek, J.15
Kulomaa, M.S.16
Nordlund, H.R.17
Supuran, C.T.18
Parkkila, S.19
-
46
-
-
0028342808
-
Calmodulin-dependent enzymes undergo a protein-induced conformational change that is associated with their interactions with calmodulin
-
S Huang GM Carlson WY Cheung 1994 Calmodulin-dependent enzymes undergo a protein-induced conformational change that is associated with their interactions with calmodulin J Biol Chem 269 7631 7638
-
(1994)
J Biol Chem
, vol.269
, pp. 7631-7638
-
-
Huang, S.1
Carlson, G.M.2
Cheung, W.Y.3
-
47
-
-
0027953972
-
H+ is involved in the activation of calcineurin by calmodulin
-
S Huang WY Cheung 1994 H+ is involved in the activation of calcineurin by calmodulin J Biol Chem 269 22067 22074
-
(1994)
J Biol Chem
, vol.269
, pp. 22067-22074
-
-
Huang, S.1
Cheung, W.Y.2
-
49
-
-
62549084241
-
Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells
-
WC Huang P Swietach RD Vaughan-Jones MD Glitsch 2009 Differentiation impairs low pH-induced Ca2+ signaling and ERK phosphorylation in granule precursor tumour cells Cell Calcium 45 391 399
-
(2009)
Cell Calcium
, vol.45
, pp. 391-399
-
-
Huang, W.C.1
Swietach, P.2
Vaughan-Jones, R.D.3
Glitsch, M.D.4
-
50
-
-
0037145037
-
Integrins: Bidirectional, allosteric signaling machines
-
RO Hynes 2002 Integrins: bidirectional, allosteric signaling machines Cell 110 673 687
-
(2002)
Cell
, vol.110
, pp. 673-687
-
-
Hynes, R.O.1
-
51
-
-
0032843103
-
Localized depolymerization of the major sperm protein cytoskeleton correlates with the forward movement of the cell body in the amoeboid movement of nematode sperm
-
JE Italiano Jr M Stewart TM Roberts 1999 Localized depolymerization of the major sperm protein cytoskeleton correlates with the forward movement of the cell body in the amoeboid movement of nematode sperm J Cell Biol 146 1087 1096
-
(1999)
J Cell Biol
, vol.146
, pp. 1087-1096
-
-
Italiano Jr, J.E.1
Stewart, M.2
Roberts, T.M.3
-
52
-
-
23744484892
-
Potentiation of TRPM7 inward currents by protons
-
J Jiang M Li L Yue 2005 Potentiation of TRPM7 inward currents by protons J Gen Physiol 126 137 150
-
(2005)
J Gen Physiol
, vol.126
, pp. 137-150
-
-
Jiang, J.1
Li, M.2
Yue, L.3
-
54
-
-
20144378365
-
Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling
-
Y Kato CA Lambert AC Colige P Mineur A Noel F Frankenne JM Foidart M Baba R Hata K Miyazaki M Tsukuda 2005 Acidic extracellular pH induces matrix metalloproteinase-9 expression in mouse metastatic melanoma cells through the phospholipase D-mitogen-activated protein kinase signaling J Biol Chem 280 10938 10944
-
(2005)
J Biol Chem
, vol.280
, pp. 10938-10944
-
-
Kato, Y.1
Lambert, C.A.2
Colige, A.C.3
Mineur, P.4
Noel, A.5
Frankenne, F.6
Foidart, J.M.7
Baba, M.8
Hata, R.9
Miyazaki, K.10
Tsukuda, M.11
-
55
-
-
34249790593
-
Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma
-
Y Kato S Ozawa M Tsukuda E Kubota K Miyazaki Y St-Pierre R Hata 2007 Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma FEBS J 274 3171 3183
-
(2007)
FEBS J
, vol.274
, pp. 3171-3183
-
-
Kato, Y.1
Ozawa, S.2
Tsukuda, M.3
Kubota, E.4
Miyazaki, K.5
St-Pierre, Y.6
Hata, R.7
-
56
-
-
2442505682
-
Pericellular proteolysis by leukocytes and tumor cells on substrates: Focal activation and the role of urokinase-type plasminogen activator
-
AL Kindzelskii I Amhad D Keller MJ Zhou RP Haugland BA Garni-Wagner MR Gyetko RF Todd 3rd HR Petty 2004 Pericellular proteolysis by leukocytes and tumor cells on substrates: focal activation and the role of urokinase-type plasminogen activator Histochem Cell Biol 121 299 310
-
(2004)
Histochem Cell Biol
, vol.121
, pp. 299-310
-
-
Kindzelskii, A.L.1
Amhad, I.2
Keller, D.3
Zhou, M.J.4
Haugland, R.P.5
Garni-Wagner, B.A.6
Gyetko, M.R.7
Todd III, R.F.8
Petty, H.R.9
-
57
-
-
0028353858
-
Regulation of the Ascaris major sperm protein (MSP) cytoskeleton by intracellular pH
-
KL King J Essig TM Roberts TS Moerland 1994 Regulation of the Ascaris major sperm protein (MSP) cytoskeleton by intracellular pH Cell Motil Cytoskelet 27 193 205
-
(1994)
Cell Motil Cytoskelet
, vol.27
, pp. 193-205
-
-
King, K.L.1
Essig, J.2
Roberts, T.M.3
Moerland, T.S.4
-
58
-
-
0034061827
-
Polarization of Na(+)/H(+) and Cl(-)/HCO(3)(-) exchangers in migrating renal epithelial cells
-
M Klein P Seeger B Schuricht SL Alper A Schwab 2000 Polarization of Na(+)/H(+) and Cl(-)/HCO(3)(-) exchangers in migrating renal epithelial cells J Gen Physiol 115 599 608
-
(2000)
J Gen Physiol
, vol.115
, pp. 599-608
-
-
Klein, M.1
Seeger, P.2
Schuricht, B.3
Alper, S.L.4
Schwab, A.5
-
60
-
-
68149151734
-
Relevance of N-glycosidic linkages of the glycocalyx for cell migration
-
H Krähling S Mally A Schwab C Stock 2008 Relevance of N-glycosidic linkages of the glycocalyx for cell migration Acta Physiol 192 Suppl 663 73
-
(2008)
Acta Physiol
, vol.192
, Issue.SUPPL. 663
, pp. 73
-
-
Krähling, H.1
Mally, S.2
Schwab, A.3
Stock, C.4
-
61
-
-
44449147036
-
Tumor cell metabolism: Cancer's Achilles' heel
-
G Kroemer J Pouyssegur 2008 Tumor cell metabolism: cancer's Achilles' heel Cancer Cell 13 472 482
-
(2008)
Cancer Cell
, vol.13
, pp. 472-482
-
-
Kroemer, G.1
Pouyssegur, J.2
-
62
-
-
0033739497
-
Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1
-
A Lagana J Vadnais PU Le TN Nguyen R Laprade IR Nabi J Noel 2000 Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1 J Cell Sci 113 Pt 20 3649 3662
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 20
, pp. 3649-3662
-
-
Lagana, A.1
Vadnais, J.2
Le, P.U.3
Nguyen, T.N.4
Laprade, R.5
Nabi, I.R.6
Noel, J.7
-
63
-
-
57049169143
-
Kindlins: Essential regulators of integrin signalling and cell-matrix adhesion
-
H Larjava EF Plow C Wu 2008 Kindlins: essential regulators of integrin signalling and cell-matrix adhesion EMBO Rep 9 1203 1208
-
(2008)
EMBO Rep
, vol.9
, pp. 1203-1208
-
-
Larjava, H.1
Plow, E.F.2
Wu, C.3
-
64
-
-
0033575007
-
Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy
-
PP Lehenkari MA Horton 1999 Single integrin molecule adhesion forces in intact cells measured by atomic force microscopy Biochem Biophys Res Commun 259 645 650
-
(1999)
Biochem Biophys Res Commun
, vol.259
, pp. 645-650
-
-
Lehenkari, P.P.1
Horton, M.A.2
-
65
-
-
23744490092
-
PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage
-
S Li R Bordoy F Stanchi M Moser A Braun O Kudlacek UM Wewer PD Yurchenco R Fassler 2005 PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage J Cell Sci 118 2913 2921
-
(2005)
J Cell Sci
, vol.118
, pp. 2913-2921
-
-
Li, S.1
Bordoy, R.2
Stanchi, F.3
Moser, M.4
Braun, A.5
Kudlacek, O.6
Wewer, U.M.7
Yurchenco, P.D.8
Fassler, R.9
-
66
-
-
33646854205
-
Cathepsin D: Newly discovered functions of a long-standing aspartic protease in cancer and apoptosis
-
E Liaudet-Coopman M Beaujouin D Derocq M Garcia M Glondu-Lassis V Laurent-Matha C Prebois H Rochefort F Vignon 2006 Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis Cancer Lett 237 167 179
-
(2006)
Cancer Lett
, vol.237
, pp. 167-179
-
-
Liaudet-Coopman, E.1
Beaujouin, M.2
Derocq, D.3
Garcia, M.4
Glondu-Lassis, M.5
Laurent-Matha, V.6
Prebois, C.7
Rochefort, H.8
Vignon, F.9
-
69
-
-
68149127795
-
Long-term treatment with the NHE1-inhibitor cariporide extends the normal lifespan of Wistar Kyoto rats
-
LW LH A Weichert U Albus 2001 Long-term treatment with the NHE1-inhibitor cariporide extends the normal lifespan of Wistar Kyoto rats Eur Heart J 22 1481
-
(2001)
Eur Heart J
, vol.22
, pp. 1481
-
-
Lh, L.W.1
Weichert, A.2
Albus, U.3
-
70
-
-
37249083542
-
Cell-matrix adhesion complexes: Master control machinery of cell migration
-
JG Lock B Wehrle-Haller S Stromblad 2008 Cell-matrix adhesion complexes: master control machinery of cell migration Semin Cancer Biol 18 65 76
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 65-76
-
-
Lock, J.G.1
Wehrle-Haller, B.2
Stromblad, S.3
-
71
-
-
33749239639
-
Oscillatory increases in alkalinity anticipate growth and may regulate actin dynamics in pollen tubes of lily
-
A Lovy-Wheeler JG Kunkel EG Allwood PJ Hussey PK Hepler 2006 Oscillatory increases in alkalinity anticipate growth and may regulate actin dynamics in pollen tubes of lily Plant Cell 18 2182 2193
-
(2006)
Plant Cell
, vol.18
, pp. 2182-2193
-
-
Lovy-Wheeler, A.1
Kunkel, J.G.2
Allwood, E.G.3
Hussey, P.J.4
Hepler, P.K.5
-
72
-
-
0042322842
-
Proton-sensing G-protein-coupled receptors
-
MG Ludwig M Vanek D Guerini JA Gasser CE Jones U Junker H Hofstetter RM Wolf K Seuwen 2003 Proton-sensing G-protein-coupled receptors Nature 425 93 98
-
(2003)
Nature
, vol.425
, pp. 93-98
-
-
Ludwig, M.G.1
Vanek, M.2
Guerini, D.3
Gasser, J.A.4
Jones, C.E.5
Junker, U.6
Hofstetter, H.7
Wolf, R.M.8
Seuwen, K.9
-
73
-
-
0034625120
-
Calcium regulation of gelsolin and adseverin: A natural test of the helix latch hypothesis
-
A Lueck HL Yin DJ Kwiatkowski PG Allen 2000 Calcium regulation of gelsolin and adseverin: a natural test of the helix latch hypothesis Biochemistry 39 5274 5279
-
(2000)
Biochemistry
, vol.39
, pp. 5274-5279
-
-
Lueck, A.1
Yin, H.L.2
Kwiatkowski, D.J.3
Allen, P.G.4
-
74
-
-
0032834211
-
Functional hierarchy of simultaneously expressed adhesion receptors: Integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices
-
K Maaser K Wolf CE Klein B Niggemann KS Zanker EB Brocker P Friedl 1999 Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices Mol Biol Cell 10 3067 3079
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3067-3079
-
-
Maaser, K.1
Wolf, K.2
Klein, C.E.3
Niggemann, B.4
Zanker, K.S.5
Brocker, E.B.6
Friedl, P.7
-
75
-
-
0027373117
-
Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells
-
R Martinez-Zaguilan RM Lynch GM Martinez RJ Gillies 1993 Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells Am J Physiol 265 C1015 1029
-
(1993)
Am J Physiol
, vol.265
, pp. 1015-1029
-
-
Martinez-Zaguilan, R.1
Lynch, R.M.2
Martinez, G.M.3
Gillies, R.J.4
-
76
-
-
0345040164
-
PH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines
-
R Martinez-Zaguilan N Raghunand RM Lynch W Bellamy GM Martinez B Rojas D Smith WS Dalton RJ Gillies 1999 pH and drug resistance. I. Functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines Biochem Pharmacol 57 1037 1046
-
(1999)
Biochem Pharmacol
, vol.57
, pp. 1037-1046
-
-
Martinez-Zaguilan, R.1
Raghunand, N.2
Lynch, R.M.3
Bellamy, W.4
Martinez, G.M.5
Rojas, B.6
Smith, D.7
Dalton, W.S.8
Gillies, R.J.9
-
77
-
-
34250683573
-
Beyond ion translocation: Structural functions of the sodium-hydrogen exchanger isoform-1
-
ME Meima JR Mackley DL Barber 2007 Beyond ion translocation: structural functions of the sodium-hydrogen exchanger isoform-1 Curr Opin Nephrol Hypertens 16 365 372
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 365-372
-
-
Meima, M.E.1
MacKley, J.R.2
Barber, D.L.3
-
79
-
-
50949128414
-
High expression of vanilloid receptor-1 is associated with better prognosis of patients with hepatocellular carcinoma
-
X Miao G Liu X Xu C Xie F Sun Y Yang T Zhang S Hua W Fan Q Li S Huang Q Wang G Liu D Zhong 2008 High expression of vanilloid receptor-1 is associated with better prognosis of patients with hepatocellular carcinoma Cancer Genet Cytogenet 186 25 32
-
(2008)
Cancer Genet Cytogenet
, vol.186
, pp. 25-32
-
-
Miao, X.1
Liu, G.2
Xu, X.3
Xie, C.4
Sun, F.5
Yang, Y.6
Zhang, T.7
Hua, S.8
Fan, W.9
Li, Q.10
Huang, S.11
Wang, Q.12
Liu, G.13
Zhong, D.14
-
80
-
-
44449089860
-
Acid treatment of melanoma cells selects for invasive phenotypes
-
RE Moellering KC Black C Krishnamurty BK Baggett P Stafford M Rain RA Gatenby RJ Gillies 2008 Acid treatment of melanoma cells selects for invasive phenotypes Clin Exp Metastasis 25 411 425
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 411-425
-
-
Moellering, R.E.1
Black, K.C.2
Krishnamurty, C.3
Baggett, B.K.4
Stafford, P.5
Rain, M.6
Gatenby, R.A.7
Gillies, R.J.8
-
81
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
MM Mohamed BF Sloane 2006 Cysteine cathepsins: multifunctional enzymes in cancer Nat Rev Cancer 6 764 775
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
82
-
-
44249086425
-
Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
-
JR Molina P Yang SD Cassivi SE Schild AA Adjei 2008 Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship Mayo Clin Proc 83 584 594
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 584-594
-
-
Molina, J.R.1
Yang, P.2
Cassivi, S.D.3
Schild, S.E.4
Adjei, A.A.5
-
83
-
-
33947236451
-
Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen
-
S Monaco M Gioia J Rodriguez GF Fasciglione D Di Pierro G Lupidi L Krippahl S Marini M Coletta 2007 Modulation of the proteolytic activity of matrix metalloproteinase-2 (gelatinase A) on fibrinogen Biochem J 402 503 513
-
(2007)
Biochem J
, vol.402
, pp. 503-513
-
-
Monaco, S.1
Gioia, M.2
Rodriguez, J.3
Fasciglione, G.F.4
Di Pierro, D.5
Lupidi, G.6
Krippahl, L.7
Marini, S.8
Coletta, M.9
-
84
-
-
34547793020
-
Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters
-
PE Morgan S Pastorekova AK Stuart-Tilley SL Alper JR Casey 2007 Interactions of transmembrane carbonic anhydrase, CAIX, with bicarbonate transporters Am J Physiol Cell Physiol 293 C738 748
-
(2007)
Am J Physiol Cell Physiol
, vol.293
, pp. 738-748
-
-
Morgan, P.E.1
Pastorekova, S.2
Stuart-Tilley, A.K.3
Alper, S.L.4
Casey, J.R.5
-
86
-
-
0034631961
-
Purification and characterization of beta-actin-rich tumor cell pseudopodia: Role of glycolysis
-
TN Nguyen HJ Wang S Zalzal A Nanci IR Nabi 2000 Purification and characterization of beta-actin-rich tumor cell pseudopodia: role of glycolysis Exp Cell Res 258 171 183
-
(2000)
Exp Cell Res
, vol.258
, pp. 171-183
-
-
Nguyen, T.N.1
Wang, H.J.2
Zalzal, S.3
Nanci, A.4
Nabi, I.R.5
-
87
-
-
0021364780
-
Calcium binding to calmodulin: Effects of ionic strength, Mg2+, pH and temperature
-
Y Ogawa M Tanokura 1984 Calcium binding to calmodulin: effects of ionic strength, Mg2+, pH and temperature J Biochem 95 19 28
-
(1984)
J Biochem
, vol.95
, pp. 19-28
-
-
Ogawa, Y.1
Tanokura, M.2
-
88
-
-
38849201787
-
Carbonic anhydrase IX/G250/MN: A molecule too good to be true?
-
E Oosterwijk 2008 Carbonic anhydrase IX/G250/MN: a molecule too good to be true? BJU Int 101 527 528
-
(2008)
BJU Int
, vol.101
, pp. 527-528
-
-
Oosterwijk, E.1
-
89
-
-
0027462558
-
Antibody localization in human renal cell carcinoma: A phase i study of monoclonal antibody G250
-
E Oosterwijk NH Bander CR Divgi S Welt JC Wakka RD Finn EA Carswell SM Larson SO Warnaar GJ Fleuren 1993 Antibody localization in human renal cell carcinoma: a phase I study of monoclonal antibody G250 J Clin Oncol 11 738 750
-
(1993)
J Clin Oncol
, vol.11
, pp. 738-750
-
-
Oosterwijk, E.1
Bander, N.H.2
Divgi, C.R.3
Welt, S.4
Wakka, J.C.5
Finn, R.D.6
Carswell, E.A.7
Larson, S.M.8
Warnaar, S.O.9
Fleuren, G.J.10
-
90
-
-
47549089080
-
Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development
-
LS Orlichenko DC Radisky 2008 Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development Clin Exp Metastasis 25 593 600
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 593-600
-
-
Orlichenko, L.S.1
Radisky, D.C.2
-
91
-
-
1242272754
-
Diversity of the mammalian sodium/proton exchanger SLC9 gene family
-
J Orlowski S Grinstein 2004 Diversity of the mammalian sodium/proton exchanger SLC9 gene family Pflugers Arch 447 549 565
-
(2004)
Pflugers Arch
, vol.447
, pp. 549-565
-
-
Orlowski, J.1
Grinstein, S.2
-
93
-
-
21644447431
-
The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells
-
A Paradiso RA Cardone A Bellizzi A Bagorda L Guerra M Tommasino V Casavola SJ Reshkin 2004 The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells Breast Cancer Res 6 R616 628
-
(2004)
Breast Cancer Res
, vol.6
, pp. 616-628
-
-
Paradiso, A.1
Cardone, R.A.2
Bellizzi, A.3
Bagorda, A.4
Guerra, L.5
Tommasino, M.6
Casavola, V.7
Reshkin, S.J.8
-
94
-
-
33748079158
-
Tumor-associated carbonic anhydrases and their clinical significance
-
S Pastorekova S Parkkila J Zavada 2006 Tumor-associated carbonic anhydrases and their clinical significance Adv Clin Chem 42 167 216
-
(2006)
Adv Clin Chem
, vol.42
, pp. 167-216
-
-
Pastorekova, S.1
Parkkila, S.2
Zavada, J.3
-
95
-
-
0034064851
-
Inhibition of the human intermediate-conductance, Ca2+-activated K+ channel by intracellular acidification
-
KA Pedersen NK Jorgensen BS Jensen SP Olesen 2000 Inhibition of the human intermediate-conductance, Ca2+-activated K+ channel by intracellular acidification Pflugers Arch 440 153 156
-
(2000)
Pflugers Arch
, vol.440
, pp. 153-156
-
-
Pedersen, K.A.1
Jorgensen, N.K.2
Jensen, B.S.3
Olesen, S.P.4
-
96
-
-
0037459075
-
Cellular motility driven by assembly and disassembly of actin filaments
-
TD Pollard GG Borisy 2003 Cellular motility driven by assembly and disassembly of actin filaments Cell 112 453 465
-
(2003)
Cell
, vol.112
, pp. 453-465
-
-
Pollard, T.D.1
Borisy, G.G.2
-
97
-
-
9144231428
-
Expression profile of genes regulated by activity of the Na-H exchanger NHE1
-
LK Putney DL Barber 2004 Expression profile of genes regulated by activity of the Na-H exchanger NHE1 BMC Genomics 5 46
-
(2004)
BMC Genomics
, vol.5
, pp. 46
-
-
Putney, L.K.1
Barber, D.L.2
-
98
-
-
8844224030
-
Microenvironmental and cellular consequences of altered blood flow in tumours
-
N Raghunand RA Gatenby RJ Gillies 2003 Microenvironmental and cellular consequences of altered blood flow in tumours Br J Radiol 76 Spec No 1 S11 S22
-
(2003)
Br J Radiol
, vol.76
, Issue.SPEC. NO 1
-
-
Raghunand, N.1
Gatenby, R.A.2
Gillies, R.J.3
-
99
-
-
0034058373
-
Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation
-
SJ Reshkin A Bellizzi V Albarani L Guerra M Tommasino A Paradiso V Casavola 2000 Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation J Biol Chem 275 5361 5369
-
(2000)
J Biol Chem
, vol.275
, pp. 5361-5369
-
-
Reshkin, S.J.1
Bellizzi, A.2
Albarani, V.3
Guerra, L.4
Tommasino, M.5
Paradiso, A.6
Casavola, V.7
-
100
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
AJ Ridley MA Schwartz K Burridge RA Firtel MH Ginsberg G Borisy JT Parsons AR Horwitz 2003 Cell migration: integrating signals from front to back Science 302 1704 1709
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
Borisy, G.6
Parsons, J.T.7
Horwitz, A.R.8
-
101
-
-
33746149756
-
Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice
-
EK Rofstad B Mathiesen K Kindem K Galappathi 2006 Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice Cancer Res 66 6699 6707
-
(2006)
Cancer Res
, vol.66
, pp. 6699-6707
-
-
Rofstad, E.K.1
Mathiesen, B.2
Kindem, K.3
Galappathi, K.4
-
103
-
-
33644959986
-
AlphaPIX and betaPIX and their role in focal adhesion formation
-
G Rosenberger K Kutsche 2006 AlphaPIX and betaPIX and their role in focal adhesion formation Eur J Cell Biol 85 265 274
-
(2006)
Eur J Cell Biol
, vol.85
, pp. 265-274
-
-
Rosenberger, G.1
Kutsche, K.2
-
104
-
-
57349151455
-
Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38
-
C Sauvant M Nowak C Wirth B Schneider A Riemann M Gekle O Thews 2008 Acidosis induces multi-drug resistance in rat prostate cancer cells (AT1) in vitro and in vivo by increasing the activity of the p-glycoprotein via activation of p38 Int J Cancer 123 2532 2542
-
(2008)
Int J Cancer
, vol.123
, pp. 2532-2542
-
-
Sauvant, C.1
Nowak, M.2
Wirth, C.3
Schneider, B.4
Riemann, A.5
Gekle, M.6
Thews, O.7
-
105
-
-
38649095658
-
H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts
-
L Schneider TK Klausen C Stock S Mally ST Christensen SF Pedersen EK Hoffmann A Schwab 2008 H-ras transformation sensitizes volume-activated anion channels and increases migratory activity of NIH3T3 fibroblasts Pflugers Arch 455 1055 1062
-
(2008)
Pflugers Arch
, vol.455
, pp. 1055-1062
-
-
Schneider, L.1
Klausen, T.K.2
Stock, C.3
Mally, S.4
Christensen, S.T.5
Pedersen, S.F.6
Hoffmann, E.K.7
Schwab, A.8
-
106
-
-
0035035910
-
Function and spatial distribution of ion channels and transporters in cell migration
-
A Schwab 2001 Function and spatial distribution of ion channels and transporters in cell migration Am J Physiol Renal Physiol 280 F739 747
-
(2001)
Am J Physiol Renal Physiol
, vol.280
, pp. 739-747
-
-
Schwab, A.1
-
107
-
-
0035257983
-
Ion channels and transporters on the move
-
A Schwab 2001 Ion channels and transporters on the move News Physiol Sci 16 29 33
-
(2001)
News Physiol Sci
, vol.16
, pp. 29-33
-
-
Schwab, A.1
-
110
-
-
27644530863
-
- Cotransport in migration of transformed renal epithelial cells
-
- cotransport in migration of transformed renal epithelial cells J Physiol 568 445 458
-
(2005)
J Physiol
, vol.568
, pp. 445-458
-
-
Schwab, A.1
Rossmann, H.2
Klein, M.3
Dieterich, P.4
Gassner, B.5
Neff, C.6
Stock, C.7
Seidler, U.8
-
112
-
-
0347885319
-
Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000
-
K Shibuya CD Mathers C Boschi-Pinto AD Lopez CJ Murray 2002 Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000 BMC Cancer 2 37
-
(2002)
BMC Cancer
, vol.2
, pp. 37
-
-
Shibuya, K.1
Mathers, C.D.2
Boschi-Pinto, C.3
Lopez, A.D.4
Murray, C.J.5
-
113
-
-
2942737069
-
Siah proteins, HIF prolyl hydroxylases, and the physiological response to hypoxia
-
MC Simon 2004 Siah proteins, HIF prolyl hydroxylases, and the physiological response to hypoxia Cell 117 851 853
-
(2004)
Cell
, vol.117
, pp. 851-853
-
-
Simon, M.C.1
-
115
-
-
33847240145
-
Intracellular pH sensors: Design principles and functional significance
-
J Srivastava DL Barber MP Jacobson 2007 Intracellular pH sensors: design principles and functional significance Physiology (Bethesda) 22 30 39
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 30-39
-
-
Srivastava, J.1
Barber, D.L.2
Jacobson, M.P.3
-
116
-
-
55749092149
-
Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling
-
J Srivastava G Barreiro S Groscurth AR Gingras BT Goult DR Critchley MJ Kelly MP Jacobson DL Barber 2008 Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling Proc Natl Acad Sci U S A 105 14436 14441
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14436-14441
-
-
Srivastava, J.1
Barreiro, G.2
Groscurth, S.3
Gingras, A.R.4
Goult, B.T.5
Critchley, D.R.6
Kelly, M.J.7
Jacobson, M.P.8
Barber, D.L.9
-
117
-
-
0035930581
-
A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers
-
D Sterling RA Reithmeier JR Casey 2001 A transport metabolon. Functional interaction of carbonic anhydrase II and chloride/bicarbonate exchangers J Biol Chem 276 47886 47894
-
(2001)
J Biol Chem
, vol.276
, pp. 47886-47894
-
-
Sterling, D.1
Reithmeier, R.A.2
Casey, J.R.3
-
118
-
-
0035188727
-
How matrix metalloproteinases regulate cell behavior
-
MD Sternlicht Z Werb 2001 How matrix metalloproteinases regulate cell behavior Annu Rev Cell Dev Biol 17 463 516
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
119
-
-
0036846879
-
- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domain
-
- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domain J Gen Physiol 120 707 722
-
(2002)
J Gen Physiol
, vol.120
, pp. 707-722
-
-
Stewart, A.K.1
Chernova, M.N.2
Shmukler, B.E.3
Wilhelm, S.4
Alper, S.L.5
-
121
-
-
23844449323
-
Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange
-
C Stock B Gassner CR Hauck H Arnold S Mally JA Eble P Dieterich A Schwab 2005 Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange J Physiol 567 225 238
-
(2005)
J Physiol
, vol.567
, pp. 225-238
-
-
Stock, C.1
Gassner, B.2
Hauck, C.R.3
Arnold, H.4
Mally, S.5
Eble, J.A.6
Dieterich, P.7
Schwab, A.8
-
123
-
-
33744832157
-
Role of the Na/H exchanger NHE1 in cell migration
-
C Stock A Schwab 2006 Role of the Na/H exchanger NHE1 in cell migration Acta Physiol (Oxf) 187 149 157
-
(2006)
Acta Physiol (Oxf)
, vol.187
, pp. 149-157
-
-
Stock, C.1
Schwab, A.2
-
124
-
-
27544508598
-
Preventing chronic diseases: How many lives can we save?
-
K Strong C Mathers S Leeder R Beaglehole 2005 Preventing chronic diseases: how many lives can we save? Lancet 366 1578 1582
-
(2005)
Lancet
, vol.366
, pp. 1578-1582
-
-
Strong, K.1
Mathers, C.2
Leeder, S.3
Beaglehole, R.4
-
125
-
-
36649014657
-
PH dependence of melanoma cell migration: Protons extruded by NHE1 dominate protons of the bulk solution
-
L Stuwe M Muller A Fabian J Waning S Mally J Noel A Schwab C Stock 2007 pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution J Physiol 585 351 360
-
(2007)
J Physiol
, vol.585
, pp. 351-360
-
-
Stuwe, L.1
Muller, M.2
Fabian, A.3
Waning, J.4
Mally, S.5
Noel, J.6
Schwab, A.7
Stock, C.8
-
126
-
-
33744961824
-
TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain
-
LT Su MA Agapito M Li WT Simonson A Huttenlocher R Habas L Yue LW Runnels 2006 TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain J Biol Chem 281 11260 11270
-
(2006)
J Biol Chem
, vol.281
, pp. 11260-11270
-
-
Su, L.T.1
Agapito, M.A.2
Li, M.3
Simonson, W.T.4
Huttenlocher, A.5
Habas, R.6
Yue, L.7
Runnels, L.W.8
-
128
-
-
8844249356
-
Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH
-
E Svastova A Hulikova M Rafajova M Zat'ovicova A Gibadulinova A Casini A Cecchi A Scozzafava CT Supuran J Pastorek S Pastorekova 2004 Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH FEBS Lett 577 439 445
-
(2004)
FEBS Lett
, vol.577
, pp. 439-445
-
-
Svastova, E.1
Hulikova, A.2
Rafajova, M.3
Zat'Ovicova, M.4
Gibadulinova, A.5
Casini, A.6
Cecchi, A.7
Scozzafava, A.8
Supuran, C.T.9
Pastorek, J.10
Pastorekova, S.11
-
129
-
-
0035870263
-
An intracellular form of cathepsin B contributes to invasiveness in cancer
-
AM Szpaderska A Frankfater 2001 An intracellular form of cathepsin B contributes to invasiveness in cancer Cancer Res 61 3493 3500
-
(2001)
Cancer Res
, vol.61
, pp. 3493-3500
-
-
Szpaderska, A.M.1
Frankfater, A.2
-
130
-
-
35548939067
-
Structural basis for ligand recognition by integrins
-
J Takagi 2007 Structural basis for ligand recognition by integrins Curr Opin Cell Biol 19 557 564
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 557-564
-
-
Takagi, J.1
-
131
-
-
0030872194
-
Release of the aspartyl protease cathepsin D is associated with and facilitates human breast cancer cell invasion
-
T Tedone M Correale G Barbarossa V Casavola A Paradiso SJ Reshkin 1997 Release of the aspartyl protease cathepsin D is associated with and facilitates human breast cancer cell invasion FASEB J 11 785 792
-
(1997)
FASEB J
, vol.11
, pp. 785-792
-
-
Tedone, T.1
Correale, M.2
Barbarossa, G.3
Casavola, V.4
Paradiso, A.5
Reshkin, S.J.6
-
132
-
-
44949190364
-
Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs
-
A Thiry CT Supuran B Masereel JM Dogne 2008 Recent developments of carbonic anhydrase inhibitors as potential anticancer drugs J Med Chem 51 3051 3056
-
(2008)
J Med Chem
, vol.51
, pp. 3051-3056
-
-
Thiry, A.1
Supuran, C.T.2
Masereel, B.3
Dogne, J.M.4
-
133
-
-
0028898489
-
Role of extracellular and intracellular acidosis for hypercapnia-induced inhibition of tension of isolated rat cerebral arteries
-
R Tian P Vogel NA Lassen MJ Mulvany F Andreasen C Aalkjaer 1995 Role of extracellular and intracellular acidosis for hypercapnia-induced inhibition of tension of isolated rat cerebral arteries Circ Res 76 269 275
-
(1995)
Circ Res
, vol.76
, pp. 269-275
-
-
Tian, R.1
Vogel, P.2
Lassen, N.A.3
Mulvany, M.J.4
Andreasen, F.5
Aalkjaer, C.6
-
134
-
-
0345446024
-
Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing
-
O Trabold S Wagner C Wicke H Scheuenstuhl MZ Hussain N Rosen A Seremetiev HD Becker TK Hunt 2003 Lactate and oxygen constitute a fundamental regulatory mechanism in wound healing Wound Repair Regen 11 504 509
-
(2003)
Wound Repair Regen
, vol.11
, pp. 504-509
-
-
Trabold, O.1
Wagner, S.2
Wicke, C.3
Scheuenstuhl, H.4
Hussain, M.Z.5
Rosen, N.6
Seremetiev, A.7
Becker, H.D.8
Hunt, T.K.9
-
135
-
-
7044224479
-
Physiological and pathological roles of alpha3beta1 integrin
-
T Tsuji 2004 Physiological and pathological roles of alpha3beta1 integrin J Membr Biol 200 115 132
-
(2004)
J Membr Biol
, vol.200
, pp. 115-132
-
-
Tsuji, T.1
-
136
-
-
0033666291
-
Paxillin and focal adhesion signalling
-
CE Turner 2000 Paxillin and focal adhesion signalling Nat Cell Biol 2 E231 236
-
(2000)
Nat Cell Biol
, vol.2
, pp. 231-236
-
-
Turner, C.E.1
-
137
-
-
0034529411
-
Paxillin interactions
-
CE Turner 2000 Paxillin interactions J Cell Sci 113 Pt 23 4139 4140
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 23
, pp. 4139-4140
-
-
Turner, C.E.1
-
138
-
-
0036965605
-
Role of bicarbonate in the regulation of intracellular pH in the mammalian ventricular myocyte
-
RD Vaughan-Jones KW Spitzer 2002 Role of bicarbonate in the regulation of intracellular pH in the mammalian ventricular myocyte Biochem Cell Biol 80 579 596
-
(2002)
Biochem Cell Biol
, vol.80
, pp. 579-596
-
-
Vaughan-Jones, R.D.1
Spitzer, K.W.2
-
139
-
-
10644270846
-
Tumor hypoxia: Causative factors, compensatory mechanisms, and cellular response
-
P Vaupel L Harrison 2004 Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response Oncologist 9 Suppl 5 4 9
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 5
, pp. 4-9
-
-
Vaupel, P.1
Harrison, L.2
-
140
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
P Vaupel F Kallinowski P Okunieff 1989 Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review Cancer Res 49 6449 6465
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
142
-
-
37249030836
-
Reorganisation of the dendritic actin network during cancer cell migration and invasion
-
D Vignjevic G Montagnac 2008 Reorganisation of the dendritic actin network during cancer cell migration and invasion Semin Cancer Biol 18 12 22
-
(2008)
Semin Cancer Biol
, vol.18
, pp. 12-22
-
-
Vignjevic, D.1
Montagnac, G.2
-
143
-
-
33745863036
-
Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells
-
WH Vila-Carriles GG Kovacs B Jovov ZH Zhou AK Pahwa G Colby O Esimai GY Gillespie TB Mapstone JM Markert CM Fuller JK Bubien DJ Benos 2006 Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells J Biol Chem 281 19220 19232
-
(2006)
J Biol Chem
, vol.281
, pp. 19220-19232
-
-
Vila-Carriles, W.H.1
Kovacs, G.G.2
Jovov, B.3
Zhou, Z.H.4
Pahwa, A.K.5
Colby, G.6
Esimai, O.7
Gillespie, G.Y.8
Mapstone, T.B.9
Markert, J.M.10
Fuller, C.M.11
Bubien, J.K.12
Benos, D.J.13
-
144
-
-
70449246776
-
Calculation of intracellular pH from the distribution of 5, 5-dimethyl-2, 4-oxazolidinedione (DMO); Application to skeletal muscle of the dog
-
WJ Waddell TC Butler 1959 Calculation of intracellular pH from the distribution of 5, 5-dimethyl-2, 4-oxazolidinedione (DMO); application to skeletal muscle of the dog J Clin Invest 38 720 729
-
(1959)
J Clin Invest
, vol.38
, pp. 720-729
-
-
Waddell, W.J.1
Butler, T.C.2
-
145
-
-
34249281332
-
The cofilin pathway in breast cancer invasion and metastasis
-
W Wang R Eddy J Condeelis 2007 The cofilin pathway in breast cancer invasion and metastasis Nat Rev Cancer 7 429 440
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 429-440
-
-
Wang, W.1
Eddy, R.2
Condeelis, J.3
-
146
-
-
34248580501
-
A novel function of capsaicin-sensitive TRPV1 channels: Involvement in cell migration
-
J Waning J Vriens G Owsianik L Stuwe S Mally A Fabian C Frippiat B Nilius A Schwab 2007 A novel function of capsaicin-sensitive TRPV1 channels: involvement in cell migration Cell Calcium 42 17 25
-
(2007)
Cell Calcium
, vol.42
, pp. 17-25
-
-
Waning, J.1
Vriens, J.2
Owsianik, G.3
Stuwe, L.4
Mally, S.5
Fabian, A.6
Frippiat, C.7
Nilius, B.8
Schwab, A.9
-
147
-
-
0036222784
-
Adhesion assembly, disassembly and turnover in migrating cells-over and over and over again
-
DJ Webb JT Parsons AF Horwitz 2002 Adhesion assembly, disassembly and turnover in migrating cells-over and over and over again Nat Cell Biol 4 E97 100
-
(2002)
Nat Cell Biol
, vol.4
, pp. 97-100
-
-
Webb, D.J.1
Parsons, J.T.2
Horwitz, A.F.3
-
148
-
-
0037211938
-
Actin, microtubules and focal adhesion dynamics during cell migration
-
B Wehrle-Haller BA Imhof 2003 Actin, microtubules and focal adhesion dynamics during cell migration Int J Biochem Cell Biol 35 39 50
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 39-50
-
-
Wehrle-Haller, B.1
Imhof, B.A.2
-
150
-
-
0038037737
-
RhoA and ROCK promote migration by limiting membrane protrusions
-
RA Worthylake K Burridge 2003 RhoA and ROCK promote migration by limiting membrane protrusions J Biol Chem 278 13578 13584
-
(2003)
J Biol Chem
, vol.278
, pp. 13578-13584
-
-
Worthylake, R.A.1
Burridge, K.2
-
151
-
-
0034671307
-
Hypoxia-inducible expression of tumor-associated carbonic anhydrases
-
CC Wykoff NJ Beasley PH Watson KJ Turner J Pastorek A Sibtain GD Wilson H Turley KL Talks PH Maxwell CW Pugh PJ Ratcliffe AL Harris 2000 Hypoxia-inducible expression of tumor-associated carbonic anhydrases Cancer Res 60 7075 7083
-
(2000)
Cancer Res
, vol.60
, pp. 7075-7083
-
-
Wykoff, C.C.1
Beasley, N.J.2
Watson, P.H.3
Turner, K.J.4
Pastorek, J.5
Sibtain, A.6
Wilson, G.D.7
Turley, H.8
Talks, K.L.9
Maxwell, P.H.10
Pugh, C.W.11
Ratcliffe, P.J.12
Harris, A.L.13
-
152
-
-
0042354714
-
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
-
J Xu F Wang A Van Keymeulen P Herzmark A Straight K Kelly Y Takuwa N Sugimoto T Mitchison HR Bourne 2003 Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils Cell 114 201 214
-
(2003)
Cell
, vol.114
, pp. 201-214
-
-
Xu, J.1
Wang, F.2
Van Keymeulen, A.3
Herzmark, P.4
Straight, A.5
Kelly, K.6
Takuwa, Y.7
Sugimoto, N.8
Mitchison, T.9
Bourne, H.R.10
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