Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na+/H+ exchange, motility, and invasion induced by serum deprivation

Journal of Biological Chemistry

Volumn 275, Issue 8, 2000, Pages 5361-5369

  Reshkin, Stephan J ^a   Bellizzi, Antonia ^a   Albarani, Valentina ^b   Guerra, Lorenzo ^a   Tommasino, Massimo ^c   Paradiso, Angelo ^b   Casavola, Valeria ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE;

ARTICLE; BREAST CANCER; CANCER INVASION; CARCINOGENESIS; CELL MOTILITY; CELL TRANSFORMATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON SODIUM EXCHANGE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOSINE TRIPHOSPHATE; AMILORIDE; AMMONIUM CHLORIDE; ANDROSTADIENES; BLOOD; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; LACTIC ACID; NEOPLASM INVASIVENESS; SODIUM-HYDROGEN ANTIPORTER; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0034058373     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.8.5361     Document Type: Article

References (56)

1. Lengauer, C., Kinzler, K. W., and Vogelstein B. (1998) Nature 396, 643-649
2. Price, J. E. (1994) J. Cell. Biochem. 13, 16-22
3. Farber, E. (1990) Biochem. Pharmacol. 39, 1837-1846
4. D'Amato, G., and Patarca, R. (1998) Crit. Rev. Oncog. 9, 275-373
5. Vaupel, P. W., Kallinowski F., and Okunieff P. (1989) Cancer Res. 49, 6449-6465
6. Vaupel, P. W. (1997) Klin. Padiatr. 209, 243-249
7. Fodstad, O. and Kjinniksen I. (1994) J. Cell. Biochem. 56, 23-28
8. Reynolds T. Y., Rockwell S., and Glazer P. M. (1996) Cancer Res. 56, 5754-5757
9. Cuvier, C., Jang, A., and Hill, R. P. (1997) Clin. Exp. Metastasis 15, 19-25
10. Gatenby, R. A., and Gawlinski E. T. (1996) Cancer Res. 56, 5745-5753
11. Martinez-Zaguilan, R., Seftor, E. A., Seftor, R. E. B., Chu, Y., Gillies, R. J., and Hendrix, M. J. C. (1996) Clin. Exp. Metastasis 14, 176-186
12. Mazure, N. M., Chen, E. Y., Yeh P., Laderoute K. R., and Giaccia, A. J. (1996) Cancer Res. 56, 3436-3440
13. Mazure, N. M., Chen E. Y., Laderoute, K. R., and Giaccia, A. J. (1997) Blood 90, 3322-3331
14. Griffiths, L., Dachs, G. U., Bicknell, R., Harris, A. L., and Stratford, I. J. (1997) Cancer Res. 57, 570-572
15. Scott, P. A., Gleadle, J. M., Bicknell, R., and Harris, A. L. (1998) Int. J. Cancer 75, 706-712
16. Graeber T. G., Osmanian C., Jacks, T., Housman D. E., Koch C. J., Lowe S.W., and Giaccia A. J. (1996) Nature 379, 88-90
17. Singh, R. K., Tsan, R., and Radinsky, R. (1997) Clin. Exp. Metastasis 15, 140-150
18. An, W. G., Kanekal, M., Simon, M. C., Maltepe, E., Blagosklonny, M. V., and Neckers, L. M. (1998) Nature 392, 405-408
19. Carmeliet, P., Dor, Y., Herbert, J-M., Fukumura, D., Brusselmans, K., Dewerchin, M., Neeman, M., Bono, F., Abramovitch, R., Maxwell, P., Koch, C. J., Ratcliffe. P., Moons, L., Jain, R. K., Collen D., and Keshert, E. (1998) Nature 394, 485-490
20. Radinsky, R. (1995) Cancer Metastasis Rev. 14, 323-338
21. Kraus, M., and Wolf, B. (1996) Tumour Biol. 17, 133-154
22. Webb, S. D., Sherratt, J. A., and Fish, R. G. (1999) J. Theor. Biol. 196, 237-250
23. Yamagata, M., Hasuda, K., Stamato, T., and Tannock, I. F. (1997) Br. J. Cancer 77, 1726-1731
24. Parkins, C. S., Stratford, M. R., Dennis, M. F., Stubbs M., and Chaplin D. J. (1997) Br. J. Cancer 75, 319-323
25. Roos, A., and Boron, W. F. (1981) Physiol. Rev. 61, 296-343
26. Boyer, M. J., and Tannock, I. F. (1992) Cancer Res. 52, 4441-4447
27. Stubbs, M., Veech, R. L., and Griffiths, J. R. (1995) Adv. Enzyme Regul. 35, 101-115
28. Hopkins, D. M., Morris, J. A., Oates K., Huddart, H., and Staff, W. G. (1992) J. Pathol. 166, 317-322
29. Soule, H. D., Maloney, T. M., Wolman, S. R., Peterson, W. D., Jr., Brenz, R., McGrath, C. M., Russo, J., Pauley, R. J., Jones, R. F., and Brooks, S. C. (1990) Cancer Res 50, 6075-6086
30. Soule, H. D., Vasquez, J., Long, A., Albert, S., and Brennan, M. (1973) J. Natl. Cancer Inst. 51, 1409-1413
31. Cailleau, R., Olivé, M., and Cruciger, Q. V. J. (1978) In Vitro 14, 911-915
32. Krayer-Pawlowska, D., Helmle-Kolb, C., Montrose, M. H., Krapf R., and Murer, H. (1991) J. Membr. Biol. 120, 173-183
33. Boron, W. F., and DeWeer, P. (1976) J. Gen. Physiol. 67, 91-112
34. Tedone, T., Correale, M., Barbarossa, G., Casavola, V., Paradiso, A., and Reshkin, S. J. (1997) FASEB J. 11, 785-792
35. Habets, G. G., Scholtes, E. H., Zuydgeest, D., van der Kammen, R. A., Stam, J. C., Berns, A., and Collard, J. G. (1994) Cell 77, 537-549
36. Brandt, R. B. (1982) Methods Enzymol. 89, 35-40
37. Reshkin, S. J., Pezzetta, A., Albarani, V., and Paradiso, A. (1995). Int. J. Oncol. 7, 371-375
38. Siczkowski, M., Davies, J. E., and Ng, L. L. (1994) Am. J. Physiol. 267, C745-C752
39. Hakomori, S. (1989) Adv. Cancer Res. 52, 257-331
40. Noel, J., and Pouysségur, J. (1995) Am. J. Physiol. 288, C283-C296
41. Gupta, A., Schweining, C. J., and Boron, W. F. (1994) Am. J. Physiol. 266, C1083-C1092
42. Kaplan, D. L., and Boron, W. F. (1994) J. Biol. Chem. 269, 4116-4124
43. Shaw, L. M., Rabinovitz, I., Wang, H. H.-F., Toker, A., and Mercurio, A. M. (1997) Cell 91, 949-960
44. Demaurex, N., Romanek, R. R., Orlowski, J., and Grinstein, S. (1997) J. Gen. Physiol. 109, 117-128
45. Price, J. E. (1996) Breast Cancer Res. Treat. 39, 93-102
46. Montcourrier, P., Silver, I., Farnoud, R., Bird, I., and Rochefort, H. (1997) Clin. Exp. Metastasis 15, 382-392
47. Watson, A. J., Levine, S., Donowitz, M., and Montrose, M. H. (1992) J. Biol. Chem. 267, 956-962
48. Reif, K., Lucas, S., and Cantrell, D. (1997) Curr. Biol. 7, 285-293
49. Hunter, T. (1997) Cell 88, 333-346
50. Rodriguez-Viciana, P., Warne, P. H., Khwaja, A., Marte, B. M., Dappin, D., Das, P., Waterfield, M. D., Ridley, A., and Downward, J. (1997) Cell 89, 457-467
51. Sander, E. E., van Delft, S., Ten Hooster, J. P., Reid, T., van der Kammen, R. A., Michiels, F., and Collard, J. G. (1998) J. Cell Biol 143, 1385-1398
52. Keely, P. J., Westwick, J. K., Whitehead, I. P., Der, C. J., and Parise, L. V. (1997) Nature 390, 632-635
53. Tominaga, T., Ishizaki, T., Narumiya, S., and Barber, D. L. (1998) EMBO J. 17, 4712-4722
54. Itoh, K., Yoshioka, K., Akedo, H., Uehata, M., Ishizaki, T., and Narumiya, S. (1999) Nat. Med. 5, 221-225
55. Plopper, G. E., McNamee, H. P., Dike, L. E., Bojanowski, K., and Ingber, D. E. (1995) Mol. Biol. Cell 6, 1349-1365
56. Tominaga, T., and Barber, D. L. (1998) Mol. Biol. Cell 9, 2287-2303