Acidic pH enhances the invasive behavior of human melanoma cells

Clinical and Experimental Metastasis

Volumn 14, Issue 2, 1996, Pages 176-186

  Martínez Zaguilán, Raul ^a   Seftor, Elisabeth A ^c   Seftor, Richard E B ^c   Chu, Yi Wen ^b   Gillies, Robert J ^a,b   Hendrix, Mary J C ^c,d  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Pediatric Research Institute   (United States)

Author keywords

Fluorescence; FURA 2; Intracellular Ca2+; Intracellular pH; Invasion; Melanoma; SNARF 1

Indexed keywords

ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MELANOMA; METASTASIS; PH;

CALCIUM; CELL MOVEMENT; CYTOPLASM; GELATINASES; HUMANS; HYDROGEN-ION CONCENTRATION; MELANOMA; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; TUMOR CELLS, CULTURED;

EID: 0029982979     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00121214     Document Type: Article

References (68)

1. Wike-Hooley JL, Haveman J and Reinhold HS, 1991, The relevance of tumour pH to the treatment of malignant disease. Radiother Oncol, 2, 343-66.
2. Griffiths JR, 1991, Are cancer cells acidic? Br J Cancer, 64, 425-7.
3. 31P NMR measurement of extracellular pH in situ using 3-aminopropylphosphonate. Am J Physiol, 267 (Cell Physiology 36), C195-C203.
4. Warburg O, 1926, Über den Stoffwechsel der Tumoren. Cambridge University Press.
5. Sevick EM and Jain RK, 1988, Blood flow and venous pH of tissue-isolated Walker 256 carcinoma during hyperglycemia. Cancer Res, 48, 1201-7.
6. Vaupel P, Kallinowski F and Okunieff P, 1989, Blood flow, oxygen and nutrient supply, and metabolic microenvironment. Cancer Res, 49, 6449-65.
7. 2H NMR spectroscopy. Proc 10th Ann Mtg Soc Magn Reson Med, p. 984.
8. Bhujwalla ZM, Tozer GM, Feld SB, Maxwell RJ and Griffiths JR, 1990, Energy metabolism of RIF-1 tumors following hydralazine. Radiother Oncol, 19, 281-91.
9. Hendrix MJC, Seftor EA, Seftor REB and Fidler IJ, 1987, A simple quantitative assay for studying the invasive potential of high and low human metastatic variants. Cancer Lett, 38, 137-47.
10. Schlappack OK, Zimmermann A and Hill RP, 1991, Glucose starvation and acidosis: effect on experimental metastasic potential, DNA content and MTX resistance of murine tumour cells. Int J Cancer, 64, 663-70.
11. Stetler-Stevenson WG, 1990, Type IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev, 9, 289-303.
12. Nicolson GL, 1992, Paracrine/autocrine growth mechanisms in tumor metastasis. Oncol Res. 4, 389-99.
13. Miller FR and Heppner GH, 1990, Cellular interactions in metastasis. Cancer Metastasis Rev, 9, 21-34.
14. Fidler IJ, 1991, Cancer metastasis. Br Med Bull, 47, 157-77.
15. Lah TT, Kokalj-Kunovar M, Strukelj B, et al. 1992, Stefins and lysosomal cathepsins B, L and D in human breast carcinoma. Int J Cancer, 50, 36-44.
16. Matrisian LM, 1992, The matrix-degrading metallo-proteinases. Bioessays, 14, 455-63.
17. Tryggvason K, Hoyhtya M and Pyke C, 1993, Type IV collagenases in invasive tumors. Breast Canc Res Treat, 24, 209-18.
18. Vassalli J-D, Sappino AP and Belin D, 1991, The plasminogen activator/plasmin system. J Clin Invest, 88, 1067-72.
19. Vassalli J-D and Pepper MS, 1994, Membrane proteases in focus. Nature, 370, 14-15.
20. Morisset M, Capony F and Rochefort H, 1986, The 52-kDa estrogen-induced protein secreted by MCF-7 cells is a lysosomal acidic protease. Biochim Biophys Res Commun, 138, 102-9.
21. Rozhin J, Sameni M, Siegler G and Sloane BF, 1994, Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. Cancer Res, 54, 6517-25.
22. Kramer MD, Robinson P, Vlodavsky I, et al. 1985, Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line. Eur J Cancer Clin Oncol, 21, 307-16.
23. Ishihara A, Nabeshima K and Koono M, 1986, Partial purification and characterization of serum protease from tumor-bearing rats which cleaves type IV collagen. Invasion & Metastasis, 6, 225-45.
24. Slivka SR and Loskutoff DJ, 1991. Platelets stimulate endothelial cells to synthesize type 1 plasminogen activator inhibitor. Evaluation of the role of transforming growth factor beta. Blood, 77, 1013-19.
25. Kato Y, Nakayama Y, Umeda M and Miyazaki K, 1992, Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines. J Biol Chem, 267, 11424-30.
26. Baker MS, Liang XM and Doe, WF, 1992, Occupancy of the cancer cell urokinase receptor (uPAR): effects of acid elution and exogenous uPA on cell surface urokinase (uPA). Biochim Biophys Acta, 1117, 143-52.
27. Uchino T, Sakurai Y, Nishigai M, et al. 1993, Isolation and characterization of a novel serine proteinase complexed with alpha 2-macroglobulin from porcine gastric mucosa. J Biol Chem, 268, 527-33.
28. Hendrix MJC, Seftor EA, Chu Y-W, et al. 1992, Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastasic potential. J Natl Cancer Inst, 84, 165-74.
29. Chu Y-W, Duffy JJ, Seftor REB, Nagle, RB and Hendrix M JC, 1991, Transfection of a deleted CK18 cDNA into a highly metastatic melanoma cell line decreases the invasive potential. Clin Biotech, 3, 27-33.
30. Schwartz MA, Both G and Lechene C, 1989, Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts. Proc Natl Acad Sci USA, 86, 4525-9.
31. Stossel TP, 1989, From signal to pseudopod. How cells control cytoplasmic actin assembly. J Biol Chem, 264, 18261-4.
32. Soifer D, 1986, Dynamic aspects of microtubule biology. Ann NY Acad Sci, 466, 1-978.
33. 2+ using the fluorescence of SNARF-1 and Fura-2. Am J Physiol, 260, C297-C307.
34. Degen DL, Estensen RD, Nagamine Y and Reich E, 1985, Induction and desensitization of plasminogen activator gene expression by tumor promoters. J Biol Chem, 260, 12426-33.
35. Angel P, Baumann I, Stein B, Delius H, Rahmsdorf HJ and Herrlich P, 1987, 12-O-Tetradecanoyld-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region. Molec Cell Biol, 7, 2256-66.
36. Frisch SM, Clark EJ and Werb Z, 1987, Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes. Proc Natl Acad Sci, USA, 84, 2600-4.
37. Edwards DR, Waterhouse P, Holman LM and Denhardt DT, 1986, A growth factor-inducible gene (16C8) in mouse fibroblasts is homologous to human tissue inhibitor of metalloproteinases. Nucl Acid Res, 14, 8863-78.
38. Murphy G and Reynolds JJ, 1985, Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin-1 in parallel with collagenase. J Biol Chem, 260, 3079-83.
39. 2+ mobilization and protein kinase C induction of spontaneous metastasis by mouse mammary adenocarcinoma cells. Cancer Res, 49, 2597-602.
40. Brinckerhoff CE, Plucinska I, Sheldon L and O'Connor GT, 1986, Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retinoic acid or dexamethasone. Biochemistry, 25, 6378-84.
41. Takenaga K and Takahashi K, 1986, Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonization ability of Lewis lung carcinoma cells. Cancer Res, 40, 375-80.
42. Gopalakrishna R and Barsky SH, 1988, Tumor-promoter induced membrane-bound kinase C regulates hematogenous metastasis. Proc Natl Acad Sci, USA, 85, 612-16.
43. Whitfield JF, Durkin JP, Franks DJ, et al. 1987, Calcium, cyclic AMP and protein kinase C: partners in mitogenesis. Cancer Metastasis Rev, 5, 205-50.
44. Barbero MC, Garcia M, Almena A and Alino SF, 1991, Correlation between secretion pattern and metastatic potential from drug-treated 3LL tumor cells line. Cell Molec Biol, 37, 501-8.
45. Moolenaar WH, 1986, Effects of growth factors on intracellular pH regulation. Ann Rev Physiol, 48, 363-76.
46. Berridge MJ, 1987, Inositol triphosphate and diacylglycerol: two interacting second messengers. Ann Rev Biochem, 56, 156-93.
47. 2+ and pH: putative signals for the control of cell growth. Life Sci, 38, 2269-76.
48. Rozengurt E, 1986, Early signals in the mitogenic response. Science, 234, 161-6.
49. Hesketh TR, Moore JP, Morris JDH, et al., 1985, A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells. Nature, 313, 481-4.
50. + exchange in mammalian cells. J Cell Physiol, 139, 125-30.
51. Marcel MM, Van Roy FM and De Baetselier P, 1990, The invasive phenotype. Cancer Metastasis Rev, 9, 45-62.
52. 2+ trt human neutrophils. J Cell Biol, 110, 43-52.
53. Milne JL and Coukell MB, 1991, A transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors. J Cell Biol, 112, 103-10.
54. Savarese DM, Russell JT, Fatatis A and Liotta LA, 1992, Type IV collagen stimulates an increase in intracellular calcium. Potential role in tumor cell motility. J Biol Chem, 267, 21928-35.
55. in in cultured cells by fluorescence spectroscopy. In: Watson, RR, ed. In Vitro Methods of Toxicology. Boca Raton, FL: CRC Press, pp. 217-36.
56. Kleinman HK, McGarvey ML, Liotta LA, et al, 1982, Isolation and characterization of type IV procollagen, laminin and heparan sulfate proteoglycan from the EHS sarcoma. Biochemistry, 21, 6188-93.
57. Bregman MD, Peters E, Sander D and Meyskens FL Jr, 1983, Dexamethasone, prostaglandin A, and retinoic acid modulation of murine and human melanoma cells grown in soft agar. J Natl Cancer Inst, 71, 927-32.
58. Gillies RJ, Martinez-Zaguilan R, Martinez GM, Serrano R and Perona R, 1990, Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. Proc Natl Acad Sci, USA, 87, 7414-18.
59. Lattanzio FA, 1990, The effects of pH and temperature on fluorescent calcium indicators as determined with chelex-100 and EDTA buffer systems. Biochem Biophys Res Commun, 171, 102-8.
60. 2+] and pH in single MDCK and glomerular epithelial cells. Am J Physiol, 265, C1184-C1190.
61. Gillies RJ, Didier N and Denton M, 1986, Determination of cell number in monolayer cultures. Analyt Biochem, 159, 109-13.
62. Matrisian LM, 1990, Metalloproteinases and their inhibitors in matrix remodeling. Trends Genetics, 6, 121-5.
63. Woessner JF, 1991, Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J, 5, 2145-54.
64. Duffy MJ, 1992, The role of proteolytic enzymes in cancer invasion and metastasis. Clin Exp Metastasis, 10, 145-55.
65. Seftor REB, 1994, Electrophoretic analysis of proteins associated with tumor cell invasion. Electrophoresis, 15, 454-62.
66. Khandjian EW, 1990, Acidic extracellular environment induces only a subset of heat-shock proteins in primary mouse kidney cell cultures. Biochem Cell Biol, 68, 804-7.
67. Mosser DD, Kotzbauer PT, Sarge KD and Morimoto RI, 1990, In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation. Proc Natl Acad Sci, USA, 87, 3748-52.
68. LeBoeuf RA, Kerckaert GA, Aardema MJ and Gibson DP, 1990, Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.7. Cancer Res, 50, 3722-9.