Tumour-stromal interactions in acid-mediated invasion: A mathematical model

Journal of Theoretical Biology

Volumn 267, Issue 3, 2010, Pages 461-470

  Martin, Natasha K ^a,b   Gaffney, Eamonn A ^a   Gatenby, Robert A ^c   Maini, Philip K ^a,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Acidity; Cancer; Microenvironment; PH; Proteases

Indexed keywords

MATRIX METALLOPROTEINASE;

ACIDITY; CANCER; CELL ORGANELLE; ENZYME; NUMERICAL MODEL; PH; TUMOR;

ACIDIFICATION; ARTICLE; CANCER INVASION; CELL DEATH; CELL DESTRUCTION; CELL ENCAPSULATION; CELL INTERACTION; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME INHIBITION; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; MATHEMATICAL MODEL; MOLECULAR INTERACTION; PREDICTION; PRIORITY JOURNAL; PROCESS MODEL; SENSITIVITY ANALYSIS; STROMA; TISSUE INTERACTION; TUMOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

ALGORITHMS; ANIMALS; CELL DEATH; COMPUTER SIMULATION; CONNECTIVE TISSUE; EXTRACELLULAR MATRIX; HUMANS; HYDROGEN-ION CONCENTRATION; METALLOPROTEASES; MODELS, BIOLOGICAL; NEOPLASM INVASIVENESS; NEOPLASMS; STROMAL CELLS; TUMOR MICROENVIRONMENT;

EID: 77958151212     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2010.08.028     Document Type: Article

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